1,346
Views
0
CrossRef citations to date
0
Altmetric
Preliminary Communication

Comparison of Liquid–Liquid Extraction, Microextraction and Ultrafiltration for Measuring Free Concentrations of Testosterone and Phenytoin

, , &
Pages 195-204 | Received 10 Nov 2021, Accepted 20 Dec 2021, Published online: 17 Jan 2022

References

  • Musteata FM , PawliszynJ, QianMG, WuJT, MiwaGT. Determination of drug plasma protein binding by solid phase microextraction. J. Pharm. Sci.95(8), 1712–1722 (2006).
  • Musteata FM , PawliszynJ. Bioanalytical applications of solid-phase microextraction. Trends Analyt. Chem.26(1), 36–45 (2007).
  • Musteata FM . Monitoring free drug concentrations – challenges. Bioanalysis3(15), 1751–1766 (2011).
  • Kodama H , KodamaY, ItokazuN, ShinozawaS, KanemaruR, SugimotoT. Effect of temperature on serum protein binding characteristics of phenytoin in monotherapy paediatric patients with epilepsy. J. Clin. Pharm. Ther.26(3), 175–179 (2001).
  • Dutta S , FaughtE, LimdiNA. Valproate protein binding following rapid intravenous administration of high doses of valproic acid in patients with epilepsy. J. Clin. Pharm. Ther.32(4), 365–371 (2007).
  • Mamiya K , YukawaE, MatsumotoT, AitaC, GotoS. Synergistic effect of valproate coadministration and hypoalbuminemia on the serum-free phenytoin concentration in patients with severe motor and intellectual disabilities. Clin. Neuropharmacol.25(4), 230–233 (2002).
  • Hackbarth JS , HoyneJB, GrebeSK, SinghRJ. Accuracy of calculated free testosterone differs between equations and depends on gender and SHBG concentration. Steroids76(1–2), 48–55 (2011).
  • Anderson GD , PakC, DoaneKWet al. Revised Winter-Tozer equation for normalized phenytoin concentrations in trauma and elderly patients with hypoalbuminemia. Ann. Pharmacother.31(3), 279–284 (1997).
  • Akhlaghi F , TrullAK. Distribution of cyclosporin in organ transplant recipients. Clin. Pharmacokinet.41(9), 615–637 (2002).
  • Seyfinejad B , OzkanSA, JouybanA. Recent advances in the determination of unbound concentration and plasma protein binding of drugs: analytical methods. Talanta225, Article 122052 (2021).
  • Seyfinejad B , KhoubnasabjafariM, ZiaeiSE, OzkanSA, JouybanA. Electromembrane extraction as a new approach for determination of free concentration of phenytoin in plasma using capillary electrophoresis. Daru. J. Pharm. Sci.28(2), 615–624 (2020).
  • Kratzer A , LiebchenU, SchleibingerM, KeesMG, KeesF. Determination of free vancomycin, ceftriaxone, cefazolin and ertapenem in plasma by ultrafiltration: impact of experimental conditions. J. Chromatogr. B961, 97–102 (2014).
  • Li X , WangF, XuBet al. Determination of the free and total concentrations of vancomycin by two-dimensional liquid chromatography and its application in elderly patients. J. Chromatogr. B969, 181–189 (2014).
  • Peltenburg H , BosmanIJ, HermensJLM. Sensitive determination of plasma protein binding of cationic drugs using mixed-mode solid-phase microextraction. J. Pharm. Biomed. Anal.115, 534–542 (2015).
  • Musteata FM . Calculation of normalized drug concentrations in the presence of altered plasma protein binding. Clin. Pharmacokinet.51(1), 55–68 (2012).
  • Cibotaru D , CelestinMN, KaneMP, MusteataFM. Method for simultaneous determination of free concentration, total concentration, and plasma binding capacity in clinical samples. J. Pharm. Sci.110(3), 1401–1411 (2021).
  • Clement M , VuT, TayefehBet al. An ultrafiltration assay for assessing the extent of whole plasma protein binding of antisense oligonucleotides in human and various species plasma (2021). https://altasciences.com/sites/default/files/Ultrafiltration%20Assay%20Assessing%20Whole%20Plasma%20Protein%20Binding%20of%20Antisense%20Oligonucleotides%20Human%20and%20Species_1.pdf

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.