129
Views
0
CrossRef citations to date
0
Altmetric
Research Article

PAAP: A Web Server for Predicting Antihypertensive Activity of Peptides

, , , &
Pages 1749-1767 | Received 27 Nov 2017, Accepted 25 Apr 2018, Published online: 24 Jul 2018

References

  • Varounis C Katsi V Nihoyannopoulos P Lekakis J Tousoulis D . Cardiovascular hypertensive crisis: recent evidence and review of the literature. Front. Cardiovasc. Med.3, 51 (2016).
  • Ikeda N Sapienza D Guerrero R et al. Control of hypertension with medication: a comparative analysis of national surveys in 20 countries. Bull. World Health Organ.92 (1), C10 – C19 (2014).
  • Loga-Zec S Asceric M Loga-Andrijic N Kapetanovic B Zerem E . The incidence of antihypertensive drug-induced side effects in patients with diabetes mellitus Type 2 and hypertension. Med. Arch.68 (6), 372 – 375 (2014).
  • Husserl FE Messerli FH . Adverse effects of antihypertensive drugs. Drugs22 (3), 188 – 210 (1981).
  • Kovell LC Ahmed HM Misra S et al. US hypertension management guidelines: a review of the recent past and recommendations for the future. J. Am. Heart Assoc.4 (12), pii:e002315 (2015).
  • Bernstein KE Giani JF Shen XZ Gonzalez-Villalobos RA . Renal angiotensin-converting enzyme and blood pressure control. Curr. Opin. Nephrol. Hypertens.23 (2), 106 – 112 (2014).
  • Wang X Wang J Lin Y et al. QSAR study on angiotensin-converting enzyme inhibitor oligopeptides based on a novel set of sequence information descriptors. J. Mol. Model.17 (7), 1599 – 1606 (2011).
  • Kumar R Chaudhary K Singh Chauhan J et al. An in silico platform for predicting, screening and designing of antihypertensive peptides. Sci. Rep.5, 12512 (2015).
  • Chou K-C . Some remarks on protein attribute prediction and pseudo amino acid composition. J. Theor. Biol.273 (1), 236 – 247 (2011).
  • Xiao N Cao D-S Zhu M-F Xu Q-S . protr/ProtrWeb: R package and web server for generating various numerical representation schemes of protein sequences. Bioinformatics31 (11), 1857 – 1859 (2015).
  • Win TS Malik AA Prachayasittikul V S Wikberg JE Nantasenamat C Shoombuatong W . HemoPred: a web server for predicting the hemolytic activity of peptides. Future Med. Chem.9 (3), 275 – 291 (2017).
  • Simeon S Shoombuatong W Anuwongcharoen N et al. osFP: a web server for predicting the oligomeric states of fluorescent proteins. J. Cheminform.8, 72 (2016).
  • Simeon S Anuwongcharoen N Shoombuatong W et al. Probing the origins of human acetylcholinesterase inhibition via QSAR modeling and molecular docking. PeerJ4, e2322 (2016).
  • Anuwongcharoen N Shoombuatong W Tantimongcolwat T Prachayasittikul V Nantasenamat C . Exploring the chemical space of influenza neuraminidase inhibitors. PeerJ4, e1958 (2016).
  • Shoombuatong W Prachayasittikul V Prachayasittikul V Nantasenamat C . Prediction of aromatase inhibitory activity using the efficient linear method (ELM). EXCLI J.14, 452 – 464 (2015).
  • Shoombuatong W Prachayasittikul V Anuwongcharoen N et al. Navigating the chemical space of dipeptidyl peptidase-4 inhibitors. Drug Des. Devel. Ther.9, 4515 – 4549 (2015).
  • Shoombuatong W Hongjaisee S Barin F Chaijaruwanich J Samleerat T . HIV-1 CRF01_AE coreceptor usage prediction using kernel methods based logistic model trees. Comput. Biol. Med.42 (9), 885 – 889 (2012).
  • Breiman L . Random Forests. Machine Learning45, 5 – 32 (2001).
  • Pratiwi R Malik AA Schaduangrat N et al. CryoProtect: a web server for classifying antifreeze proteins from nonantifreeze proteins. J. Chem. 2017, 9861752 (2017).
  • Wang L Huang C Yang JY . Predicting siRNA potency with random forests and support vector machines. BMC. Genomics.11 (Suppl. 3), S2 (2010).
  • Shoombuatong W Nabu S Simeon S et al. Extending proteochemometric modeling for unraveling the sorption behavior of compound–soil interaction. Chemometr. Intell. Lab. Syst.151, 219 – 227 (2016).
  • Wu J Aluko RE Nakai S . Structural requirements of angiotensin I-converting enzyme inhibitory peptides: quantitative structure-activity relationship study of di- and tripeptides. J. Agric. Food Chem.54 (3), 732 – 738 (2006).
  • Kumar R Chaudhary K Sharma M et al. AHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides. Nucleic Acids Res.43, D956 – D962 (2015).
  • Hernández-Ledesma B del Mar Contreras M Recio I . Antihypertensive peptides: production, bioavailability and incorporation into foods. Adv. Colloid. Interface Sci.165 (1), 23 – 35 (2011).
  • Yamamoto N Ejiri M Mizuno S . Biogenic peptides and their potential use. Curr. Pharm. Des.9 (16), 1345 – 1355 (2003).
  • Thévenet P Shen Y Maupetit J Guyon F Derreumaux P Tufféry P . PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides. Nucleic Acids Res.40, W288 – W293 (2012).
  • DeLano WL . The PyMOL Molecular Graphics System. Schrödinger, LLC., NY, USA. http://pymol.org
  • Siebert KJ . Quantitative structure–activity relationship modeling of peptide and protein behavior as a function of amino acid composition. J. Agric. Food Chem.49 (2), 851 – 858 (2001).
  • Mishra B Wang G . The importance of amino acid composition in natural amps: an evolutional, structural, and functional perspective. Front. Immunol.3, 221 (2012).
  • Nie L Siebert KJ . Modeling physicochemical properties and activity of aspartyl proteinases based on amino acid composition. J. Agric. Food Chem.57 (6), 2536 – 2543 (2009).
  • Yamamoto N Maeno M Takano T . Purification and characterization of an antihypertensive peptide from a yogurt-like product fermented by Lactobacillus helveticus CPN4. J. Dairy Sci.82 (7), 1388 – 1393 (1999).
  • Pan D Luo Y Tanokura M . Antihypertensive peptides from skimmed milk hydrolysate digested by cell-free extract of Lactobacillus helveticus JCM1004. Food. Chem.91 (1), 123 – 129 (2005).
  • Nakamura Y Yamamoto N Sakai K Takano T . Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme. J. Dairy Sci.78 (6), 1253 – 1257 (1995).
  • Sipola M Finckenberg P Korpela R Vapaatalo H Nurminen M-L . Effect of long-term intake of milk products on blood pressure in hypertensive rats. J. Dairy Res.69 (1), 103 – 111 (2002).
  • Lameu C Hayashi MAF Guerreiro JR et al. The central nervous system as target for antihypertensive actions of a proline-rich peptide from Bothrops jararaca venom. Cytometry A77 (3), 220 – 230 (2010).
  • Arcanjo DDR Vasconcelos AG Comerma-Steffensen SG et al. A novel vasoactive proline-rich oligopeptide from the skin secretion of the frog Brachycephalus ephippium. PLoS ONE10 (12), e0145071 (2015).
  • Jäkälä P Vapaatalo H . Antihypertensive peptides from milk proteins. Pharmaceuticals (Basel)3 (1), 251 – 272 (2010).
  • Nakamura Y Yamamoto N Sakai K Okubo A Yamazaki S Takano T . Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J. Dairy Sci.78 (4), 777 – 783 (1995).
  • Manzanares P Salom JB García-Tejedor A Fernández-Musoles R Ruiz-Giménez P Gimeno-Alcañíz JV . Unraveling the mechanisms of action of lactoferrin-derived antihypertensive peptides: ACE inhibition and beyond. Food Funct.6 (8), 2440 – 2452 (2015).
  • Robert M-C Razaname A Mutter M Juillerat MA . Identification of angiotensin-I-converting enzyme inhibitory peptides derived from sodium caseinate hydrolysates produced by Lactobacillus helveticus NCC 2765. J. Agric. Food. Chem.52 (23), 6923 – 6931 (2004).
  • Pripp AH . Initial proteolysis of milk proteins and its effect on formation of ACE-inhibitory peptides during gastrointestinal proteolysis: a bioinformatic, in silico, approach. Eur. Food. Res. Technol.221 (5), 712 – 716 (2005).
  • He R Ma H Zhao W et al. Modeling the QSAR of ACE-inhibitory peptides with ANN and its applied illustration. Int. J. Pept. 2012, 620609 (2012).
  • Mullally MM Meisel H FitzGerald RJ . Synthetic peptides corresponding to a-lactalbumin and b-lactoglobulin sequences with angiotensin-1-converting enzyme inhibitory activity. Biol. Chem. Hoppe Seyler.377 (4), 259 – 260 (1996).
  • Pihlanto-Leppala A Rokka T Korhonen H . Angiotensin I converting enzyme inhibitory peptides derived from bovine milk proteins. Int. Dairy J.8 (4), 325 – 331 (1998).
  • Pihlanto-Leppälä A Koskinen P Piilola K Tupasela T Korhonen H . Angiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. J. Dairy Res.67 (1), 53 – 64 (2000).
  • Pripp AH Isaksson T Stepaniak L S⊘rhaug T . Quantitative structure–activity relationship modelling of ACE-inhibitory peptides derived from milk proteins. Eur. Food Res. Technol.219 (6), 579 – 583 (2004).
  • Gebauer S Friebe S Scherer G Gubitz G Krauss G-J . High performance liquid chromatography on calixarene-bonded silica gels. III. Seperations of cis/trans isomers of proline-containing peptides. J. Chromatogr. Sci.36, 388 – 394 (1998).
  • Siltari A Viitanen R Kukkurainen S Vapaatalo H Valjakka J . Does the cis/trans configuration of peptide bonds in bioactive tripeptides play a role in ACE-1 enzyme inhibition?Biologics8, 59 – 65 (2014).
  • Li G-H Le G-W Shi Y-H Shrestha S . Angiotensin I– converting enzyme inhibitory peptidesderived from food proteins and their physiological andpharmacological effects. Nutr. Res.24, 469 – 486 (2004).
  • Kohmura M Nio N Kubo K Minoshima Y Munekata E Ariyoshi Y . Inhibition of angiotensin-converting enzyme by synthetic peptides of human β-casein. Agric. Biol. Chem.53 (8), 2107 – 2114 (1989).
  • Pripp AH Ardo Y . Modelling relationship between angiotensin-(I)-converting enzyme inhibition and the bitter taste of peptides. Food Chem.102 (2007), 880 – 888 (2006).
  • Wu S Qi W Su R Li T Lu D He Z . CoMFA and CoMSIA analysis of ACE-inhibitory, antimicrobial and bitter-tasting peptides. Eur. J. Med. Chem.84, 100 – 106 (2014).
  • Pereira MA Jacobs DR Van Horn L Slattery ML Kartashov AI Ludwig DS . Dairy consumption, obesity, and the insulin resistance syndrome in young adults: The CARDIA study. JAMA287, 2081 – 2089 (2002).
  • Appel LJ Moore TJ Obarzanek E et al. A clinical trial of the effects of dietary patterns on blood pressure. N. Engl. J. Med.336, 1117 – 1124 (1997).
  • van Beresteijn EC van Schaik M Schaafsma G . Milk: does it affect blood pressure? A controlled intervention study. J. Intern. Med.228, 477 – 482 (1990).
  • Alonso A Steffen LM Folsom AR . Dairy intake and changes in blood pressure over 9 years: the ARIC study. Eur. J. Clin. Nutr.63, 1272 – 1275 (2009).
  • Wang L . Dietary intake of dairy products, calcium, and vitamin D and the risk of hypertension in middle-aged and older women. Hypertension51, 1073 – 1079 (2008).
  • Toledo E Delgado-Rodríguez M Estruch R et al. Low-fat dairy products and blood pressure: follow-up of 2290 older persons at high cardiovascular risk participating the PREDIMED study. Br. J. Nutr.101, 59 – 67 (2009).
  • He J Whelton PK . Effect of dietary fiber and protein intake on blood pressure: a review of epidemiological evidence. Clin. Exp. Hypertens.21, 785 – 796 (1999).
  • Meisel H Bockelmann W . Bioactive peptides encrypted in milk proteins: proteolytic activation and thropho-functional properties. Antonie Van Leeuwenhoek76, 207 – 215 (1999).
  • Sipola M Finckenberg P Santisteban J Korpela R Vapaatalo H Nurminen ML . Long term intake of milk peptides attenuates development of hypertension in spontaneously hypertensive rats. J. Physiol. Pharmacol.52, 745 – 754 (2001).
  • Hata Y Yamamoto M Ohni M Nakajima K Nakamura Y Takano T . A placebo-controlled study of the effect of sour milk on blood pressure in hypertensive subjects. Am. J. Clin. Nutr.64, 767 – 71 (1996).
  • Seppo L Kerojoki O Suomalainen T Korpela R . The effect of a Lactobacillus helveticus LBK-16 H fermented milk on hypertension – a pilot study on humans. Milchwissenschaft57, 124 – 127 (2002).
  • Xu J-Y Qin L-Q Wang P-Y Li W Chang C . Effect of milk tripeptides on blood pressure: a meta-analysis of randomized controlled trials. Nutrition28, 933 (2008).
  • Pripp AH . Effect of peptides derived from food proteins on blood pressure: a meta-analysis of randomized controlled trials. Food Nutr. Res.52, 1 (2008).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.