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Future Medicinal Chemistry Volume 3, 2011 - Issue 7
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Editorial

The Risks of Subconscious Biases in Drug-Discovery Decision Making

Matthew Segalla Optibrium Ltd, 7226 IQ Cambridge, Beach Drive, Cambridge, CB25 9TL, UKCorrespondence[email protected]
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Andrew Chadwickb Tessella Plc, Bretby Business Park, Ashby Road, Stanhope Bretby, Burton upon Trent, DE15 0YZ, UKView further author information
Pages 771-774 | Published online: 06 Jun 2011

Bibliography

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  • Chadwick AT , SegallMD. Overcoming psychological barriers to good discovery decisions.Drug Discov. Today15(13–14), 561–569 (2010).
  • Sanfey AG , ChangLJ. Of two minds when making a decision. Scientific American. 3 June 2008.
  • Tversky A , KahnemanD. Judgment under uncertainty: heuristics and biases.Science185(4157), 1124–1131 (1974).
  • Lichtenstein S , SlovicP, FischhoffB, LaymanM, CombsB. Judged frequency of lethal events.J. Exp. Psychol. Hum. Learn.4(6), 551–578 (1978).
  • Hardman D . Judgment and Decision Making. BPS Blackwell, Oxford, UK (2009).
  • Segall MD , BeresfordAP, GolaJM, HawksleyD, TarbitMH. Focus on success: using in silico optimization to achieve an optimal balance of properties. Expert Opin. Drug Metab. Toxicol.2(2), 325–337 (2006).

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