References
- Gordon CP , KellerPA. Control of hepatitis C: a medicinal chemistry perspective. J. Med. Chem.48 (1), 01–20 (2004).
- Mouritsen CL , HillyardDR. Clinical analyzersMicrobiol. Anal. Chem.71 (12), 366–372 (1999).
- Huang Z , MurrayMG, SecristJA. Development of therapeutics for chronic HCV infection. Antiviral Res.71 (2–3), 351–362 (2006).
- Madela K , McGuiganC. Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs. Future Med. Chem.4 (5), 625–650 (2012).
- Leung D , AbbenanteG, FairlieDP. Protease inhibitors: current status and future prospects. J. Med. Chem.43 (3), 305–341 (2000).
- Nakamoto S , KandaT, WuSet al. Hepatitis C virus NS5A inhibitors and drug resistance mutations. World J. Gastroenterol.20 (11), 2902–2912 (2014).
- Gane EJ , AgarwalK. Directly acting antivirals (DAAs) for the treatment of chronic hepatitis C virus infection in liver transplant patients: “a flood of opportunity”. Am. J. Transplant.14 (5), 994–1002 (2014).
- Li H , ShiST. Non-nucleoside inhibitors of hepatitis C virus polymerase: current progress and future challenges. Future Med. Chem.2 (1), 121–141 (2010).
- Salam KA , FurutaA, NodaNet al. Inhibition of hepatitis C virus NS3 helicase by manoalide. J. Nat. Prod.75 (4), 650–54 (2012).
- Berger KL , LagacéL, TrikiIet al. Viral resistance in hepatitis C virus genotype 1-infected patients receiving the ns3 protease inhibitor faldaprevir (BI 2013 35) in a phase 1b multiple-rising-dose study. Antimicrob. Agents. Chemother.57 (10), 4928–4936 (2013).
- Delang L , VliegenI, FroeyenMet al. Comparative study of the genetic barriers and pathways towards resistance of selective inhibitors of hepatitis C virus replication. Antimicrob. Agents. Chemother.55, 4103–4113 (2011).
- Chatterji U , Garcia-RiveraJ, BaughJet al. The combination of alisporivir plus an NS5A inhibitor provides additive to synergistic anti-Hepatitis C virus activity without detectable cross-resistance. Antimicrob. Agents. Chemother.58 (9), 3327–3334 (2014).
- Guan L , DisneyMD. Recent advances in developing small molecules targeting RNA. ACS Chem. Biol.7 (1), 73–86 (2011).
- Chromy LR , PipasJM, GarceaRL. Chaperone-mediated in vitro assembly of polyomavirus capsids. Proc. Natl Acad. Sci. USA100 (18), 10477–10482 (2003).
- Ivanovic T , AgostoMA, ChandranKet al. A role for molecular chaperone Hsc70 in reovirus outer capsid disassembly. J. Biol. Chem.282 (16), 12210–12219 (2007).
- Parent R , QuXY, PetitMAet al. The heat shock cognate protein 70 is associated with hepatitis C virus particles and modulates virus infectivity. Hepatology49 (6), 1798–1809 (2007).
- Peng ZG , FanB, DuNNet al. Small molecular compounds that inhibit hepatitis C virus replication through destabilizing heat shock cognate 70 messenger RNA. Hepatology52 (3), 845–853 (2010).
- Liu T , DanielsCK, CaoSS. Comprehensive review on the Hsc70 functions, interactions with related molecules and involvement in clinical diseases and therapeutic potential. Pharmacol. Ther.136 (3), 354–374 (2012).
- Eddy EM . HSP70–2 heat-shock protein of mouse spermatogenic cells. J. Exp. Zool.282 (1–2), 261–271 (1998).
- Gang Z , FrancescPB, BoZet al. A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitor. Virology384 (1), 242–252 (2009).
- Gabrielsen B , MonathTP, HugginsJWet al. Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances. J. Nat. Prod.55 (11), 1569–1581 (1992).
- Ieven M , VlietinckAJ, VandenBDAet al. Plant antiviral agents. III. Isolation of alkaloids from Clivia miniata regel (Amaryllidaceae). J. Nat. Prod.45 (5), 564–573 (1982).
- Gorska M , MarinoGA, ZmijewskiMAet al. Geldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (Hsp60). PLoS ONE8 (8), e71135 (2013).
- Kim JA , KimY, KwonBMet al. The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 and Bcl-2-associated athanogene domain 3 expression by blocking heat shock factor 1 binding to promoters. J. Biol. Chem.288 (40), 28713–28726 (2013).
- Babine RE : WO 2002 018369A2 (2002).
- Lohmann V , KornerF, KochJOet al. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science285 (5424), 110–113 (1999).
- Lamoral-Theys D , AndolfiA, Van GoietsenovenGet al. Lycorine, the main phenanthridine amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight. J. Med. Chem.52 (20), 6244–6256 (2009).
- Toriizuka Y , KinoshitaE, KogureNet al. New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives. Bioorg. Med. Chem.16 (24), 10182–10189 (2008).
- Lee SS , VenkateshamU, RaoCPet al. Preparation of secolycorines against acetylcholinesterase. Bioorg. Med. Chem.15 (2), 1034–1043 (2007).