Recent Progress in Natural Products as DPP-4 Inhibitors

References

• Hung HY , QianKD, Morris-NatschkeSLet al. Recent discovery of plant-derived anti-diabetic natural products, Nat. Prod. Rep.29, 580–606 (2012).
   PubMed Web of Science ®Google Scholar
• Arif T , SharmaB, GahlautAet al. Anti-diabetic agents from medicinal plants: a review, Chem. Biol. Lett.1, 1–13 (2014).
   Google Scholar
• Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus, World Health Organization, http://whqlibdoc.who.int/hq/1999/who_ncd_ncs_99.2.pdf.
   Google Scholar
• Attele AS , ZhouYP, XieJTet al. Anti-diabetic effects of Panax ginseng berry extracts and the identification of an effective component. Diabetes51, 1851–1858 (2002).
   PubMed Web of Science ®Google Scholar
• Kshirsagar AD , AggarwalAS, HarleUNet al. DPP IV inhibitors: Ssuccesses, failures and future prospects. Diabetes Metab. Syndr.5, 105–112 (2011).
   PubMedGoogle Scholar
• Wang X , LiY, GuiXRet al. Progress in dipeptidyl peptidase-4 and its inhibitors. Chin. Pharm. J.48, 1789–1796 (2013).
   Google Scholar
• Gurudeeban S , SatyavaniK, RamanathanTet al. Dipeptidyl peptidase IV inhibitors derived from a mangrove flora Rhizophora mucronata: an in silico approach. Bangladesh J. Pharmacol.7, 203–210 (2012).
   Web of Science ®Google Scholar
• Mentlein R . Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides. Regul. Pept.85, 9–24 (1999).
   PubMed Web of Science ®Google Scholar
• Holst JJ , Vilsb⊘llT, DeaconCF. The incretin system and its role in type 2 diabetes mellitus. Mol. Cell. Endocrinol.297, 127–136 (2009).
   PubMed Web of Science ®Google Scholar
• Deacon CF . Circulation and degradation of GIP and GLP-1. Horm. Metab. Res.36, 761–765 (2004).
   PubMed Web of Science ®Google Scholar
• Duez H , CariouB, StaelsB. DPP-4 inhibitors in the treatment of type 2 diabetes. Biochem. Pharmacol.83, 823–832 (2012).
   PubMed Web of Science ®Google Scholar
• Richard KR , ShelburneJS, KirkJK. Tolerability of dipeptidyl peptidase-4 inhibitors: a review. Clin. Ther.33, 1609–1629 (2011).
   PubMed Web of Science ®Google Scholar
• Simpkins LM , BoltonS, PiZet al. Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors. Bioorg. Med. Chem. Lett.17, 6476–6480 (2007).
   PubMed Web of Science ®Google Scholar
• Jia XD , ZhangJ. Comparison of clinical pharmacokinetics of five marketed DPP-4 inhibitors. World Notes on Antibiotics, 35, 23–27 (2014).
   Google Scholar
• Noh YH , LimHS, JinSJet al. Effects of ketoconazole and rifampicin on the pharmacokinetics of gemigliptin, a dipeptidyl peptidase-IV inhibitor: a crossover drug-drug interaction study in healthy male Korean volunteers. Clin. Ther.34, 1182–1194 (2012).
   PubMed Web of Science ®Google Scholar
• Kishimoto M . Teneligliptin: a DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab. Syndr. Obes.6, 187–195 (2013).
   PubMedGoogle Scholar
• Filippatos TD , AthyrosVG, ElisafMS. The pharmacokinetic considerations and adverse effects of DPP-4 inhibitors. Expert Opin. Drug Metab. Toxicol. 10, 787–812 (2014).
   Google Scholar
• Prabhakar PK and DobleM. A Target Based Therapeutic Approach Towards Diabetes Mellitus Using Medicinal Plants. Curr. Diabetes Rev.4, 291–308 (2008).
   PubMedGoogle Scholar
• Fan Jf , JohnsonMH, LilaMAet al. Berry and citrus phenolic compounds inhibit dipeptidyl peptidase IV: implications in diabetes management. Evid. Based Complement. Alternat. Med.2013, 1–13 (2013).
   Web of Science ®Google Scholar
• Zhang L . Identification of Isoquercitrin as a Inhibitor of DPP-IV: Implications for Insulin Secretion and Hyperglycemic in Type 2 Diabetes Mice. Doctoral Dissertation, Jilin University, China, 1–99 (2013).
   Google Scholar
• Bower AM , Real HernandezLM, BerhowMAet al. Bioactive compounds from culinary herbs inhibit a molecular target for type-2 diabetes management, dipeptidyl peptidase-IV. J. Agric. Food Chem.62, 6147–6158 (2014).
   PubMed Web of Science ®Google Scholar
• Parmar HS , JainP, ChauhanDSet al. DPP-IV inhibitory potential of naringin: an in silico, in vitro and in vivo study. Diabetes Res. Clin. Pract.97, 105–111 (2012).
   PubMed Web of Science ®Google Scholar
• Al-masri IM , MohammadMK, TahaaMO. Inhibition of dipeptidyl peptidase IV (DPP IV) is one of the mechanisms explaining the hypoglycemic effect of berberine. J. Enzyme Inhib. Med. Chem.24, 1061–1066 (2009).
   PubMed Web of Science ®Google Scholar
• Bustanji Y , TahaMO, YousefAet al. Berberine potently inhibits protein tyrosine phosphatase 1B: investigation by docking simulation and experimental validation. J. Enzyme Inhib. Med. Chem.21, 163–171 (2006).
   PubMed Web of Science ®Google Scholar
• Guasch L , OjedaMJ, González-AbuínNet al. Identification of Novel Human Dipeptidyl Peptidase-IV Inhibitors of Natural Origin (Part I): Virtual Screening and Activity Assays. PLOS ONE7, 1–13 (2012).
   Web of Science ®Google Scholar
• Guasch L , SalaE, OjedaMJet al. Identification of novel human dipeptidyl peptidase-IV inhibitors of natural origin (Part II): <i>in silico</i> prediction in anti-diabetic extracts. PLOS ONE7, 1–7 (2012).
   Web of Science ®Google Scholar
• Geng Y , LuZM, HuangWet al. Bioassay-Guided Isolation of DPP-4 inhibitory fractions from extracts of submerged cultured of Inonotus obliquus. Molecules18, 1150–1161 (2013).
   PubMed Web of Science ®Google Scholar
• Huang NL . Inonotus obliquus. Edible Fungi of China21, 7–8 (2002).
   Google Scholar
• Ayachi H , MeradM, GhalemS. Study of interaction between dipeptidyl peptidase-4 and products extractsed from the stevia plant by molecular modeling. Int. J. Pharm. Sci. Rev. Res.23, 87–90 (2013).
   Google Scholar
• Umezawa H , AoyagiT, OgawaKet al. Diprotins A and B, inhibitors of dipeptidyl aminopeptidase IV, produced by bacteria. J. Antibiot.37, 422–425 (1984).
   PubMed Web of Science ®Google Scholar
• Pieter B . JW. WO 2006068480A2 (2006).
   Google Scholar
• Huang SL , JaoCL, HoKPet al. Dipeptidyl-peptidase IV inhibitory activity of peptides derived from tuna cooking juice hydrolysates. Peptides35, 114–121 (2012).
   PubMed Web of Science ®Google Scholar
• Tulipano G , SibiliaV, CaroliMAet al. Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors. Peptides32, 835–838 (2011).
   PubMed Web of Science ®Google Scholar
• Uchida M , OhshibaY, MogamiO. Novel Dipeptidyl Peptidase-4-Inhibiting Peptide Derived From β-Lactoglobulin. J. Pharmacol Sci.117, 63–66 (2011).
   PubMed Web of Science ®Google Scholar
• Tulipano G , CocchiD, CaroliAM. Comparison of goat and sheep β-lactoglobulin to bovine β-lactoglobulin as potential source of dipeptidyl peptidase IV (DPP-4) inhibitors. Int. Dairy J.24, 97–101 (2012).
   Web of Science ®Google Scholar
• Li-Chan ECY , HunagSL, JaoCLet al. Peptides derived from atlantic salmon skin gelatin as dipeptidyl-peptidase IV iInhibitors. J. Agric. Food Chem.60, 973–978 (2012).
   PubMed Web of Science ®Google Scholar
• Velarde-Salcedo AJ , Barrera-PachecoA, Lara-GonzálezSet al. In vitro inhibition of dipeptidyl peptidase IV by peptides derived from the hydrolysis of amaranth (Amaranthus hypochondriacus L.) proteins. Food Chem.136, 758–764 (2013).
   PubMed Web of Science ®Google Scholar
• González-Abuín N , Martínez-MicaeloN, BlayMet al. Grape seed-derived procyanidins decrease dipeptidyl-peptidase 4 activity and expression. J. Agric. Food Chem.60, 9055–9061 (2012).
   PubMed Web of Science ®Google Scholar
• Kosaraju J , DubalaA, ChinniSet al. A molecular connection of Pterocarpus marsupium, Eugenia jambolana and Gymnema sylvestre with dipeptidyl peptidase-4 in the treatment of diabetes. Pharm. Biol.52, 268–271 (2014).
   PubMed Web of Science ®Google Scholar
• Pascual I , LopézA, GómezHet al. Screening of inhibitors of porcine dipeptidyl peptidase IV activity in aqueous extracts from marine organisms. Enzyme Microb. Technol.40, 414–419 (2007).
   Web of Science ®Google Scholar
• Yang ZZ . Three Kinds of Plants in Xinjiang on Dipeptidyl Peptidase IV Inhibition Activity. Master Dissertation, Xinjiang Medical University, China, 1–45 (2012).
   Google Scholar
• Miao L . Screening the Dipeptidyl Peptidase IV Inhibitors from the Chinese Herb and it's Pharmacodynamics. Master Dissertation, Jiangnan University, China, 1–44 (2008).
   Google Scholar
• Bansal P , PaulP, MudgalJet al. Anti-diabetic, antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/streptozotocin-induced diabetes in mice. Exp. Toxicol. Pathol.64, 651–658 (2012).
   PubMed Web of Science ®Google Scholar
• Wang HJ and ChiangBH. Anti-diabetic effect of a traditional Chinese medicine formula. Food Funct.3, 1161–1169 (2012).
   PubMed Web of Science ®Google Scholar
• Hu JZ , HuGW. Screeing for dipeptidyl peptidase IV inhibition research. Food Sci. Technol.2, 42–43 (2012).
   Google Scholar
• Li WL , WangJX, WuXMet al. Recent progress in research and development of dipeptidyl peptidase IV inhibitors. Chin. J. New Drugs17, 1739–1745 (2008).
   Google Scholar
• Cragg GM , GrothausPG, NewmanDJ. Impact of natural products on developing new anti-cancer agents. Chem. Rev.109, 3012–3043 (2009).
   PubMed Web of Science ®Google Scholar