References
- Rogers E , AlderdiceF , McCallE , JenkinsJ , CraigS. Reducing nosocomial infections in neonatal intensive care. J. Matern. Fetal Neonatal. Med.23(9), 1039–1046 (2010).
- American Thoracic Society IDSoA . Guidelines for the management of adults with hospital-acquired, ventilator-associated and healthcare-associated pneumonia. Am. J. Respir. Crit. Care Med.171(4), 388–416 (2005).
- Rello J , DiazE. Pneumonia in the intensive care unit. Crit. Care Med.31(10), 2544–2551 (2003).
- Fagon JY , ChastreJ , HanceAJ , DomartY , TrouilletJL , GibertC. Evaluation of clinical judgment in the identification and treatment of nosocomial pneumonia in ventilated patients. Chest103(2), 547–553 (1993).
- Ewig S , TorresA , El-EbiaryMet al. Bacterial colonization patterns in mechanically ventilated patients with traumatic and medical head injury. Incidence, risk factors and association with ventilator-associated pneumonia. Am. J. Respir. Crit. Care Med.159(1), 188–198 (1999).
- Safdar N , CrnichCJ , MakiDG. The pathogenesis of ventilator-associated pneumonia: its relevance to developing effective strategies for prevention. Respir. Care50(6), 725–739739–741 (2005).
- Drulis-Kawa Z , GubernatorJ , Dorotkiewicz-JachA , DoroszkiewiczW , KozubekA. In vitro antimicrobial activity of liposomal meropenem against Pseudomonas aeruginosa strains. Int. J. Pharm.315(1–2), 59–66 (2006).
- Bassetti M , LuytCE , NicolauDP , PuginJ. Characteristics of an ideal nebulized antibiotic for the treatment of pneumonia in the intubated patient. Ann. Intensive Care6(1), 35 (2016).
- Cabov T , MacanD , HusedzinovicIet al. The impact of oral health and 0.2% chlorhexidine oral gel on the prevalence of nosocomial infections in surgical intensive-care patients: a randomized placebo-controlled study. Wien Klin Wochenschr.122(13–14), 397–404 (2010).
- Li Bassi G , SenussiT , AguileraXiol E. Prevention of ventilator-associated pneumonia. Curr. Opin. Infect. Dis.30(2), 214–220 (2017).
- Jeong B , KimSW , BaeYH. Thermosensitive sol–gel reversible hydrogels. Adv. Drug Deliv. Rev.54(1), 37–51 (2002).
- Giuliano E , PaolinoD , FrestaM , CoscoD. Drug-loaded biocompatible nanocarriers embedded in poloxamer 407 hydrogels as therapeutic formulations. Medicines (Basel)6(1), 7 (2018).
- Bakker-Woudenberg IA , StormG , WoodleMC. Liposomes in the treatment of infections. J. Drug Target.2(5), 363–371 (1994).
- Vanaja K , WahlMA , BukaricaL , HeinleH. Liposomes as carriers of the lipid soluble antioxidant resveratrol: evaluation of amelioration of oxidative stress by additional antioxidant vitamin. Life Sci.93(24), 917–923 (2013).
- Shobha Rani R , VanajaK. Application of plackett burman screening design in the formulation of ultradeformable liposomes containing methotrexate. Indian Drugs45(3), 181 (2008).
- Tristram-Nagle SA . Preparation of oriented, fully hydrated lipid samples for structure determination using x-ray scattering. Methods Mol. Biol.400, 63–75 (2007).
- Yu-Xin Zhao C-LG , Wei-TaoYao , Qi-QinCai , Yi-ShengWang , Jia-QiangWang. Vitamin E TPGS based liposomal delivery of doxorubicin in osteosarcoma cancer cells. Biomed. Res.28(3), 1344–1349 (2017).
- Vanaja K , ShobhaRani RH , SacchidanandaS. Formulation and clinical evaluation of ultradeformable liposomes in the topical treatment of psoriasis. Clin. Res. Regulatory Affairs25(1), 41–52 (2008).
- Mendez AS , SteppeM , SchapovalEE. Validation of HPLC and UV spectrophotometric methods for the determination of meropenem in pharmaceutical dosage form. J. Pharm. Biomed. Anal.33(5), 947–954 (2003).
- Jin R , HiemstraC , ZhongZ , FeijenJ. Enzyme-mediated fast in situ formation of hydrogels from dextran-tyramine conjugates. Biomaterials28(18), 2791–2800 (2007).
- Pendekal SM , TegginamatKP. Formulation and evaluation of a bioadhesive patch for buccal delivery of tizanidine. Acta Pharm. Sin. B2(3), 318–324 (2012).
- Zuidam NJ , LeeSS , CrommelinDJ. Gamma-irradiation of non-frozen, frozen and freeze-dried liposomes. Pharm. Res.12(11), 1761–1768 (1995).
- Turker S , OzerAY , KiliçE , OzalpM , ColakS , KorkmazM. Gamma-irradiated liposome/noisome and lipogelosome/niogelosome formulations for the treatment of rheumatoid arthritis. Interv. Med. Appl. Sci.5(2), 60–69 (2013).
- Gregoriadis G . Engineering liposomes for drug delivery: progress and problems. Trends Biotechnol.13(12), 527–537 (1995).
- Sharma A , SharmaUS. Liposomes in drug delivery: progress and limitations. Int. J. Pharm.154(2), 123–140 (1997).
- Zahra MJ , HamedH , MohammadRY , NosratollahZ , AkbarzadehA , MortezaM. Evaluation and study of antimicrobial activity of nanoliposomal meropenem against Pseudomonas aeruginosa isolates. Artificial Cells45(5), 975–980 (2017).
- Abdelbary G , El-GendyN. Niosome-encapsulated gentamicin for ophthalmic controlled delivery. AAPS PharmSciTech9(3), 740–747 (2008).
- Elhissi AM , GiebultowiczJ , StecAAet al. Nebulization of ultradeformable liposomes: the influence of aerosolization mechanism and formulation excipients. Int. J. Pharm.436(1–2), 519–526 (2012).
- Ahad A , Al-SalehAA , Al-MohizeaAMet al. Formulation and characterization of novel soft nanovesicles for enhanced transdermal delivery of eprosartan mesylate. Saudi Pharm. J.25(7), 1040–1046 (2017).
- Ruel-Gariepy E , LeclairG , HildgenP , GuptaA , LerouxJC. Thermosensitive chitosan-based hydrogel containing liposomes for the delivery of hydrophilic molecules. J. Control. Rel.82(2–3), 373–383 (2002).
- Mourtas S , FotopoulouS , DurajS , SfikaV , TsakiroglouC , AntimisiarisSG. Liposomal drugs dispersed in hydrogels: effect of liposome, drug and gel properties on drug release kinetics. Colloids Surf. B Biointerfaces55(2), 212–221 (2007).
- Pavelic Z , Skalko-BasnetN , SchubertR , JalsenjakI. Liposomal gels for vaginal drug delivery. Methods Enzymol.387, 287–299 (2004).
- Zuidam NJ , VersluisC , VernooyEA , CrommelinDJ. Gamma-irradiation of liposomes composed of saturated phospholipids: effect of bilayer composition, size, concentration and absorbed dose on chemical degradation and physical destabilization of liposomes. Biochim. Biophys. Acta1280(1), 135–148 (1996).
- Jean SS , HsuehPR. Current review of antimicrobial treatment of nosocomial pneumonia caused by multidrug-resistant pathogens. Expert Opin. Pharmacother.12(14), 2145–2148 (2011).
- Spencer RC . Predominant pathogens found in the European Prevalence of Infection in Intensive Care Study. Eur. J. Clin. Microbiol. Infect. Dis.15(4), 281–285 (1996).
- Jaruratanasirikul S , SriwiriyajanS. Stability of meropenem in normal saline solution after storage at room temperature. Southeast Asian J. Trop. Med. Public Health34(3), 627–629 (2003).
- Alhajlan M , AlhaririM , OmriA. Efficacy and safety of liposomal clarithromycin and its effect on Pseudomonas aeruginosa virulence factors. Antimicrob. Agents Chemother.57(6), 2694–2704 (2013).
- Nicolau DP . Pharmacokinetic and pharmacodynamic properties of meropenem. Clin. Infect. Dis.47(Suppl. 1), S32–S40 (2008).
- Iorgulescu G . Saliva between normal and pathological. Important factors in determining systemic and oral health. J. Med. Life2(3), 303–307 (2009).
- Gregoriadis G . Overview of liposomes. J. Antimicrob. Chemother.28(Suppl. B), 39–48 (1991).
- Ong HX , TrainiD , CipollaDet al. Liposomal nanoparticles control the uptake of ciprofloxacin across respiratory epithelia. Pharm. Res.29(12), 3335–3346 (2012).
- Mitsopoulos P , OmriA , AlipourM , VermeulenN , SmithMG , SuntresZE. Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. Int. J. Pharm.363(1–2), 106–111 (2008).
- Drulis-Kawa Z , GubernatorJ , Dorotkiewicz-JachA , DoroszkiewiczW , KozubekA. A comparison of the in vitro antimicrobial activity of liposomes containing meropenem and gentamicin. Cell. Mol. Biol. Lett.11(3), 360–375 (2006).
- Park SN , LeeMH , KimSJ , YuER. Preparation of quercetin and rutin-loaded ceramide liposomes and drug-releasing effect in liposome-in-hydrogel complex system. Biochem. Biophys. Res. Commun.435(3), 361–366 (2013).
- Hurler J , ZakeljS , MravljakJet al. The effect of lipid composition and liposome size on the release properties of liposomes-in-hydrogel. Int. J. Pharm.456(1), 49–57 (2013).
- Giuliano E , PaolinoD , FrestaM , CoscoD. Mucosal applications of poloxamer 407-based hydrogels: an overview. Pharmaceutics10(3), 159 (2018).