References
- Swarbrick J . Pharmaceutical Technology. In: Encyclopedia of Pharmaceutical Technology (Volume 3). James Swarbrick (Ed.). Informa Health, Zug, Switzerland (2007).
- Bruin S , Van Zuilichem DJ, Stolp W. A review of fundamental and engineering aspects of extrusion of biopolymers in a single-screw extruder. J. Food Process Eng.2(1), 1–37 (1978).
- Ghebre-Sellassie I , MartinC, DekkerM. Pharmaceutical Extrusion Technology. Ghebre-Sellassie I, Martin C (Eds). CRC Press, Boca Raton, FL, USA, 1–16, 17–35 (2003).
- Particle Sciences Drug Development Services. Technical Brief Volume 3 – Hot-Melt Extrusion. Particle Sciences, Inc. Drug Development Services, PA, USA, 1–2 (2011).
- Quintavalle U , VoinovichD, PerissuttiBet al. Preparation of sustained release co-extrudates by hot-melt extrusion and mathematical modelling of in vitro/in vivo drug release profiles. Eur. J. Pharm. Sci. 33(3), 282–293 (2008).
- Giles HF . Extrusion: The Definitive Processing Guide and Handbook. William Andrew Publishing, Norwich, NY, USA (2005).
- Sinhal S , LoharVK, AroraV. Hot-melt extrusion technique. Webmed Central Pharm. Sci.1(2), WMC001459 (2011).
- Kolter K , KarlM, NalawadeS, RottmannS. Hot-Melt Extrusion with BASF Pharma Polymers. Extrusion Compendium. BASF. (2011).
- Repka MA . Hot-melt extrusion. Am. Pharm. Rev.12(6), 18–27 (2009).
- Andrews GP , JonesDS, Abu Diak O, Margetson DN. Hot-melt extrusion: an emerging drug-delivery technology. Pharm. Technol. Eur.21(1), 18–23 (2009).
- Breitenbach J . Melt extrusion: from process to drug delivery technology Eur. J. Pharm. Biopharm.54(2), 107–117 (2002).
- Potente H , AnsahlJ, KlarholzB. Design of tightly intermeshing co-rotating twin screw extruders. Int. Polym. Process.9(1), 11–15 (1994).
- Wagner JR . Multilayer flexible packaging. In: Technology and Applications for the Food, Personal Care and Over the Counter Pharmaceutical Industries. (Volume 1). John R, Wanger Jr (Eds). William Andrew Publishing, MA, USA (2009).
- Liesl KM . Chapter 65. Multilayer films – polyvinylidene chloride barriers. In: Permeability Properties of Plastics and Elastomers, Second Edition: a Guide to Packaging and Barrier Materials. Elsevier, Amsterdam, The Netherlands (2002).
- Saerens L , DierickxL, LenainB, VervaetC, RemonJP, BeerTD. Raman spectroscopy for the in-line polymer–drug quantification and solid state characterization during a pharmaceutical hot-melt extrusion process. Eur. J. Pharm. Biopharm.77(1), 158–163 (2011).
- Köster M , ThommesM. In-line dynamic torque measurement in twin-screw extrusion process. Chem. Eng. J.164(2–3), 371–375 (2010).
- Wang L , TianY, LiuR. Dependence of glass forming ability on liquid fragility: thermodynamics versus kinetics. Appl. Phys. Lett.97(18), 181901 (2010).
- Wang Y , SteinhoffB, BrinkmannC, AligI. In-line monitoring of the thermal degradation of poly(l-lactic acid) during melt extrusion by UV–vis spectroscopy. Polymer49(5), 1257–1265 (2008).
- Alig I , SteinhoffB, LellingerD. Monitoring of polymer melt processing. Meas. Sci. Technol.21(6), 1–19 (2010).
- Barnes SE , SibleyMG, EdwardsHGM, CoatesPD. Process monitoring of polymer melts using in-line spectroscopy. Trans. Inst. Meas. Control.29(5), 453–465 (2007).
- Leuner C , DressmanJ. Improving drug solubility for oral delivery using solid dispersions. Eur. J. Pharm. Biopharm.50, 47–60 (2000).
- Sinha S , BabootaS, AliM, KumarA, AliJ. Solid dispersion: an alternative technique for bioavailability enhancement of poorly soluble drugs. J. Dispers. Sci. Technol.30(10), 1458–1473 (2009).
- Serajuddin A , KowalskiJ, CaoY, LakshmanJ. Application of melt extrusion in the development of a physically and chemically stable high-energy amorphous solid dispersion of a poorly water-soluble drug. Mol. Pharm.5(6), 994–1002 (2008).
- Forster A , HempenstallJ, TuckerI, RadesT. Selection of excipients for meltextrusion with two poorly water-soluble drugs by solubility parameter calculation and thermal analysis. Int. J. Pharm.226(1–2), 147–161 (2001).
- Dinunzio J , BroughC, MillerD, WilliamsIR, McGinityJ. Fusion processing of itraconazole solid dispersions by KinetiSol® dispersing: a comparative study to hot-melt extrusion. J. Pharm. Sci.99, 1239–1253 (2010).
- Vasconcelos T , SarmentoB, CostaP. Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs. Drug Discov. Today12(23–24), 1068–1075 (2007).
- Brouwers J , BrewsterM, AugustijnsP. Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability? J. Pharm. Sci.98(8), 2549–2572 (2009).
- Shanbhag A , RabelS, NaukaEet al. Method for screening of solid dispersion formulations of low-solubility compounds – miniturization and automation of solvent casting and dissolution testing. Int. J. Pharm. 351, 209–218 (2008).
- Tiwari R , TiwariG, SrivastavaB, RaiA. Solid dispersions: an overview to modify bioavailability of poorly water soluble drugs. Int. J. Pharm. Tech. Res.1(4), 1338–1349 (2009).
- Patel PS , RavalJP, PatelHV. Review on the pharmaceutical applications of hot-melt extruder. J. Pharm. Clin. Res.3, 80–83 (2010).
- Kennedy M , HuJ, GaoPet al. Enhanced bioavailability of a poorly soluble vr1 antagonist using an amorphous solid dispersion approach: a case study. Mol. Pharm. 5, 981–993 (2008).
- Crowley MM , ZhangF, RepkaMAet al. Pharmaceutical applications of hot-melt extrusion: part I. Drug Dev. Ind. Pharm. 33(9), 909–926 (2007).
- Janssens S , Van den Mooter G. Review: physical chemistry of solid dispersions. J. Pharm. Pharmacol.61(12), 1571–1586 (2009).
- Verhoeven E , De Beer TRM, Van den Mooter G. Remon JP, Vervaet C. Influence of formulation and process parameters on the release characteristics of ethylcellulose sustained-release mini-matrices produced by hot-melt extrusion. Eur. J. Pharm. Biopharm.69(1), 312–319 (2008).
- Matsumoto T , ZografiG. Physical properties of solid molecular dispersions of indomethacin with poly(vinylopyrrolidone) and poly(vinylpyrrolidone-co-vinyl-acetate) in relation to indomethacin crystallization. Pharm. Res.16(11), 1722–1728 (1999).
- Van Arnum P . Exploring excipient functionality. Pharm. Tech.35(5), 6–11 (2011).
- Sauceau M , FagesJ, CommonA, NikitineC, RodierE. New challenges in polymer foaming: a review of extrusion processes assisted by supercritical carbon dioxide. Prog. Polym. Sci.36(6), 749–766 (2011).
Websites
- Slide Share. R&B Plastics Machinery. Basic screw geometry. Things your screw designer never told you about screws!! www.slideshare.net/rbplastics/things-your-extruder-screw-designer-never-told-you-about-screws-slideshow
- Thermo Scientific. Chirkot T, Halsey S, Swanborough A. Monitoring the output of pharmaceutical hot melt extruders with near-infrared spectroscopy. www.thermo.com/eThermo/CMA/PDFs/Various/File_53248.pdf (Accessed 10November2011)
- HAAKE. MiniLab II micro compounder. https://thermoscientific.com/ecomm/servlet/productsdetail_11152_L11280_82128_11961612_-1 (Accessed 24November2011)
- Caleva. Caleva mini screw extruder. www.caleva.com/caleva_mini_screw_extruder.html (Accessed 24November2011)
- Rondol. 10mm microlab. www.rondol.com/products/30/twin-screw-compounders.html (Accessed 24November2011)
- Leistritz. NANO 16 – extremely small volume combined with a revolutionary feeder system. www.leistritz.com/extrusion/en/04_products/laborextruder/nano16.html (Accessed 24November2011)
- Evonik. Degussa provides pharmaceutical melt extrusion technology services. http://corporate.evonik.com/en/media/press_releases/pages/news-details.aspx?newsid=20084 (Accessed 24November2011)
- Ashland Inc. Ashland Inc. adds clinical-scale, hot-melt extrusion technology for poorly soluble compounds. www.ashland.com/vgn-ext-templating/v/index.jsp?vgnextoid=d975d7c5c3043310VgnVCM1000004a373795RCRD (Accessed 24November2011)