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Therapeutic Delivery Volume 6, 2015 - Issue 3
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Editorial

The Potential Use of Trigeminal Nerve Stimulation in the Treatment of Epilepsy

Ian A Cooka University of California, Los Angeles, CA, USA;b NeuroSigma, Inc, Los Angeles, CA, USACorrespondence[email protected]
,
Colin P Kealeya University of California, Los Angeles, CA, USA;b NeuroSigma, Inc, Los Angeles, CA, USA
&
Christopher M DeGiorgioa University of California, Los Angeles, CA, USA;b NeuroSigma, Inc, Los Angeles, CA, USA
Pages 273-275 | Published online: 08 Apr 2015

References

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  • Murray CJ Vos T Lozano R et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet380 (9859), 2197–2223 (2012).
  • Téllez-Zenteno JF Hernández-Ronquillo L Buckley S Zahagun R Rizvi S . A validation of the new definition of drug-resistant epilepsy by the International League Against Epilepsy. Epilepsia55 (6), 829–834 (2014).
  • Fasano A Deuschl G . Patients and DBS targets: is there any rationale for selecting them?Basal Ganglia2 (4), 211–219 (2012).
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  • Fanselow EE Reid AP Nicolelis MA . Reduction of pentylenetetrazole-induced seizure activity in awake rats by seizure-triggered trigeminal nerve stimulation. J. Neurosci.20 (21), 8160–8168 (2000).
  • Fanselow EE . Central mechanisms of cranial nerve stimulation for epilepsy. Surg. Neurol. Int.3 (Suppl. 4), S247–S254 (2012).
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  • DeGiorgio CM Murray D Markovic D Whitehurst T . Trigeminal nerve stimulation for epilepsy: long-term feasibility and efficacy. Neurology72 (10), 936–938 (2009).
  • DeGiorgio CM Soss J Cook IA et al. Randomized controlled trial of trigeminal nerve stimulation for drug-resistant epilepsy. Neurology80 (9), 786–791 (2013).
  • Soss J Heck C Murray D et al. A prospective long-term study of external trigeminal nerve stimulation for drug-resistant epilepsy. Epilepsy Behav.42, 44–47 (2015).
  • Cook IA Schrader LM Degiorgio CM Miller PR Maremont ER Leuchter AF . Trigeminal nerve stimulation in major depressive disorder: acute outcomes in an open pilot study. Epilepsy Behav.28 (2), 221–226 (2013).
  • Pop J Murray D Markovic D DeGiorgio CM . Acute and long-term safety of external trigeminal nerve stimulation for drug-resistant epilepsy. Epilepsy Behav.22 (3), 574–576 (2011).
  • Sinha G . Charged by GSK investment, battery of electroceuticals advance. Nat. Med.19 (6), 654 (2013).

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