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Editorial

Subcutaneous Administration of Monoclonal antibodies: A Small Space to inject, a Big Challenge to Conquer

Pages 5-6 | Published online: 10 Dec 2015

References

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  • Shieu W Torhan S Chan E et al. Filling of high-concentration monoclonal antibody formulations into pre-filled syringes: filling parameter investigation and optimization. PDA J. Pharm. Sci. Tech.68 (5), 153–163 (2014).
  • Allmendinger A Fischer S Huwyler J et al. Rheological characterization and injection forces of concentrated protein formulations. An alternative predictive model for non-Newtonian solutions. Eur. J. Pharm. Biopharm.87 (2), 318–328 (2014).
  • Shameem M Mach H Chakraverty N . High-dose monoclonal antibodies via the subcutaneous route: challenges and technical solutions, an industry perspective. Ther. Deliv.3 (7), 889–900 (2012).

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