Chromosome segregation and organization are targets of 5′-Fluorouracil in eukaryotic cells

References

• Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer 2003; 3:330-8; PMID:12724731; http://dx.doi.org/10.1038/nrc1074
   PubMed Web of Science ®Google Scholar
• Santi DV, McHenry CS, Sommer H. Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. Biochemistry 1974; 13:471-81; PMID:4203910; http://dx.doi.org/10.1021/bi00700a012
   PubMed Web of Science ®Google Scholar
• Parker WB, Cheng YC. Metabolism and mechanism of action of 5-fluorouracil. Pharmacol Ther 1990; 48:381-95; PMID:1707544; http://dx.doi.org/10.1016/0163-7258(90)90056-8
   PubMed Web of Science ®Google Scholar
• Kufe DW, Major PP. 5-Fluorouracil incorporation into human breast carcinoma RNA correlates with cytotoxicity. J Biol Chem 1981; 256:9802-5; PMID:7275977
   PubMed Web of Science ®Google Scholar
• Glazer RI, Lloyd LS. Association of cell lethality with incorporation of 5-fluorouracil and 5-fluorouridine into nuclear RNA in human colon carcinoma cells in culture. Mol Pharmacol 1982; 21:468-73; PMID:7099147
   PubMed Web of Science ®Google Scholar
• Mojardin L, Botet J, Quintales L, Moreno S, Salas M. New insights into the RNA-based mechanism of action of the anticancer drug 5’-Fluorouracil in eukaryotic cells. PLoS One 2013; 8:e78172; PMID:24223771; http://dx.doi.org/10.1371/journal.pone.0078172
   PubMed Web of Science ®Google Scholar
• Takeda K, Mori A, Yanagida M. Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe. PLoS One 2011; 6:e22021; PMID:21760946; http://dx.doi.org/10.1371/journal.pone.0022021
   PubMed Web of Science ®Google Scholar
• Zhou X, Ma Y, Fang Y, gerile W, Jaiseng W, Yamada Y, Kuno T. A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe. PLoS One 2013; 8:e65904; PMID:23738021; http://dx.doi.org/10.1371/journal.pone.0065904
   PubMed Web of Science ®Google Scholar
• Fang Y, Hu L, Zhou X, Jaiseng W, Zhang B, Takami T, Kuno T (2012) A genomewide screen in Schizosaccharomyces pombe for genes affecting the sensitivity of antifungal drugs that target ergosterol biosynthesis. Antimicrob Agents Chemother 2012; 56:1949-59; PMID:22252817; http://dx.doi.org/10.1128/AAC.05126-11
   PubMed Web of Science ®Google Scholar
• Zhang L, Ma N, Liu Q, Ma Y. Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast. PLoS One 2013; 8:e68738; PMID:23861937; http://dx.doi.org/10.1371/journal.pone.0068738
   PubMed Web of Science ®Google Scholar
• Clayton AL, Hazzalin CA, Mahadevan LC. Enhanced histone acetylation and transcription: a dynamic perspective. Mol Cell 2006; 23:289-96; PMID:16885019; http://dx.doi.org/10.1016/j.molcel.2006.06.017
   PubMed Web of Science ®Google Scholar
• Carrozza MJ, Utley RT, Workman JL, Cote J. The diverse functions of histone acetyltransferase complexes. Trends Genet 2003; 19:321-9; PMID:12801725; http://dx.doi.org/10.1016/S0168-9525(03)00115-X
   PubMed Web of Science ®Google Scholar
• Rodriguez-Navarro S. Insights into SAGA function during gene expression. EMBO Rep 2009; 10:843-50; PMID:19609321; http://dx.doi.org/10.1038/embor.2009.168
   PubMed Web of Science ®Google Scholar
• Doyon Y, Selleck W, Lane WS, Tan S, Cote J. Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans. Mol Cell Biol 2004; 24:1884-96; PMID:14966270; http://dx.doi.org/10.1128/MCB.24.5.1884-1896.2004
   PubMed Web of Science ®Google Scholar
• Yang XJ, Seto E. The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men. Nat Rev Mol Cell Biol 2008; 9:206-18; PMID:18292778; http://dx.doi.org/10.1038/nrm2346
   PubMed Web of Science ®Google Scholar
• Dehé PM, Dichtl B, Schaft D, Roguev A, Pamblanco M, Lebrun R, Rodríguez-Gil A, Mkandawire M, Landsberg K, Shevchenko A, et al. Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation. J Biol Chem 2006; 281:35404-12; http://dx.doi.org/10.1074/jbc.M603099200
   PubMed Web of Science ®Google Scholar
• Dehé PM, Géli V. The multiple faces of Set1. Biochem Cell Biol 2006; 84:536-48; http://dx.doi.org/10.1139/o06-081
   PubMed Web of Science ®Google Scholar
• Guillemette B, Gaudreau L. Reuniting the contrasting functions of H2A.Z. Biochem Cell Biol 2006; 84:528-35; PMID:16936825; http://dx.doi.org/10.1139/o06-077
   PubMed Web of Science ®Google Scholar
• Hou H, Wang Y, Kallgren SP, Thompson J, Yates JR 3rd, Jia S. Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast. J Biol Chem 2010; 285:1909-18; PMID:19910462; http://dx.doi.org/10.1074/jbc.M109.058487
   PubMed Web of Science ®Google Scholar
• Rangasamy D, Greaves I, Tremethick DJ. RNA interference demonstrates a novel role for H2A.Z in chromosome segregation. Nat Struct Mol Biol 2004; 11: 650-65; PMID:15195148; http://dx.doi.org/10.1038/nsmb786
   PubMed Web of Science ®Google Scholar
• Greaves IK, Rangasamy D, Ridgway P, Tremethick DJ. H2A.Z contributes to the unique 3D structure of the centromere. Proc Natl Acad Sci U S A 2007; 104:525-30; PMID:17194760; http://dx.doi.org/10.1073/pnas.0607870104
   PubMed Web of Science ®Google Scholar
• Zofall M, Grewal SI. HULC, a histone H2B ubiquitinating complex, modulates heterochromatin independent of histone methylation in fission yeast. J Biol Chem 2007; 282:14065-72; PMID:17363370; http://dx.doi.org/10.1074/jbc.M700292200
   PubMed Web of Science ®Google Scholar
• Sadeghi L, Siggens L, Svensson JP, Ekwall K. Centromeric histone H2B monoubiquitination promotes noncoding transcription and chromatin integrity. Nat Struct Mol Biol 2014; 21:236-43; PMID:24531659; http://dx.doi.org/10.1038/nsmb.2776
   PubMed Web of Science ®Google Scholar
• Zhang K, Mosch K, Fischle W, Grewal SI. Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin. Nat Struct Mol Biol 2008; 15:381-8; PMID:18345014; http://dx.doi.org/10.1038/nsmb.1406
   PubMed Web of Science ®Google Scholar
• Verdel A, Jia S, Gerber S, Sugiyama T, Gygi S, Grewal SI, Moazed D. RNAi-mediated targeting of heterochromatin by the RITS complex. Science 2004; 303:672-6; PMID:14704433; http://dx.doi.org/10.1126/science.1093686
   PubMed Web of Science ®Google Scholar
• Creamer KM, Partridge JF. RITS-connecting transcription, RNA interference, and heterochromatin assembly in fission yeast. Wiley Interdiscip Rev 2011; RNA 2:632-46; http://dx.doi.org/10.1002/wrna.80
   Google Scholar
• Martin V, Du LL, Rozenzhak S, Russell P. Protection of telomeres by a conserved Stn1-Ten1 complex. Proc Natl Acad Sci U S A 2007; 104:14038-43; PMID:17715303; http://dx.doi.org/10.1073/pnas.0705497104
   PubMed Web of Science ®Google Scholar
• Bryan C, Rice C, Harkisheimer M, Schultz DC, Skordalakes E. Structure of the human telomeric Stn1-Ten1 capping complex. PLoS One 2013; 8:e66756; PMID:23826127; http://dx.doi.org/10.1371/journal.pone.0066756
   PubMed Web of Science ®Google Scholar
• Lee JH, Park JH, Jung Y, Kim JH, Jong HS, Kim TY, Bang YJ. Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells. Mol Cancer Ther 2006; 5:3085-95; PMID:17172411; http://dx.doi.org/10.1158/1535-7163.MCT-06-0419
   PubMed Web of Science ®Google Scholar
• Iwahashi S, Ishibashi H, Utsunomiya T, Morine Y, Ochir TL, Hanaoka J, Mori H, Ikemoto T, Imura S, Shimada M. Effect of histone deacetylase inhibitor in combination with 5-fluorouracil on pancreas cancer and cholangiocarcinoma cell lines. J Med Invest 2011; 58:106-9; PMID:21372494; http://dx.doi.org/10.2152/jmi.58.106
   PubMedGoogle Scholar
• Yu SL, Lee DC, Son JW, Park CG, Lee HY, Kang J. Histone deacetylase 4 mediates SMAD family member 4 deacetylation and induces 5-fluorouracil resistance in breast cancer cells. Oncol Rep 2013; 30:1293-300; PMID:23817620
   PubMed Web of Science ®Google Scholar
• Matuo R, Sousa FG, Bonatto D, Mielniczki-Pereira AA, Saffi J, Soares DG, Escargueil AE, Larsen AK, Henriques JA. ATP-dependent chromatin remodeling and histone acetyltransferases in 5-FU cytotoxicity in Saccharomyces cerevisiae. Genet Mol Res 2013; 12:1440-56; PMID:23661467; http://dx.doi.org/10.4238/2013.April.26.6
   PubMed Web of Science ®Google Scholar
• Kanellopoulou C, Muljo SA, Kung AL, Ganesan S, Drapkin R, Jenuwein T, Livingston DM, Rajewsky K. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 2005; 19:489-501; PMID:15713842; http://dx.doi.org/10.1101/gad.1248505
   PubMed Web of Science ®Google Scholar
• Fukagawa T, Nogami M, Yoshikawa M, Ikeno M, Okazaki T, Takami Y, Nakayama T, Oshimura M. Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat Cell Biol 2004; 6:784-91; PMID:15247924; http://dx.doi.org/10.1038/ncb1155
   PubMed Web of Science ®Google Scholar
• Motamedi MR, Verdel A, Colmenares SU, Gerber SA, Gygi SP, Moazed D. Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell 2004; 119:789-802; PMID:15607976; http://dx.doi.org/10.1016/j.cell.2004.11.034
   PubMed Web of Science ®Google Scholar
• Ekwall K, Javerzat JP, Lorentz A, Schmidt H, Cranston G, Allshire R. The chromodomain protein Swi6: a key component at fission yeast centromeres. Science 1995; 269:1429-31; PMID:7660126; http://dx.doi.org/10.1126/science.7660126
   PubMed Web of Science ®Google Scholar
• Allshire RC, Nimmo ER, Ekwall K, Javerzat JP, Cranston G. Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation. Genes Dev 1995; 9:218-33; PMID:7851795; http://dx.doi.org/10.1101/gad.9.2.218
   PubMed Web of Science ®Google Scholar
• Peters AH, O’Carroll D, Scherthan H, Mechtler K, Sauer S, Schofer C, Weipoltshammer K, Pagani M, Lachner M, Kohlmaier A, et al. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 2001; 107:323-37; PMID:11701123; http://dx.doi.org/10.1016/S0092-8674(01)00542-6
   PubMed Web of Science ®Google Scholar
• Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 2001; 410:120-4; PMID:11242054; http://dx.doi.org/10.1038/35065138
   PubMed Web of Science ®Google Scholar
• Cheutin T, McNairn AJ, Jenuwein T, Gilbert DM, Singh PB, Misteli T. Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science 2003; 299:721-5; PMID:12560555; http://dx.doi.org/10.1126/science.1078572
   PubMed Web of Science ®Google Scholar
• Bernard P, Maure JF, Partridge JF, Genier S, Javerzat JP, Allshire RC. Requirement of heterochromatin for cohesion at centromeres. Science 2001; 294:2539-42; PMID:11598266; http://dx.doi.org/10.1126/science.1064027
   PubMed Web of Science ®Google Scholar
• Tanaka K, Hao Z, Kai M, Okayama H. Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism. EMBO J 2001; 20:5779-90; PMID:11598020; http://dx.doi.org/10.1093/emboj/20.20.5779
   PubMed Web of Science ®Google Scholar
• Wang SW, Read RL, Norbury CJ. Fission yeast Pds5 is required for accurate chromosome segregation and for survival after DNA damage or metaphase arrest. J Cell Sci 2002; 115:587-98; PMID:11861765
   PubMed Web of Science ®Google Scholar
• Losada A, Yokochi T, Hirano T. Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts. J Cell Sci 2005; 118:2133-41; PMID:15855230; http://dx.doi.org/10.1242/jcs.02355
   PubMed Web of Science ®Google Scholar
• Bhattacharjee S, Osman F, Feeney L, Lorenz A, Bryer C, Whitby MC. MHF1-2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination. Open Biol 2013; 3:130102; PMID:24026537; http://dx.doi.org/10.1098/rsob.130102
   PubMed Web of Science ®Google Scholar
• Nishino T, Takeuchi K, Gascoigne KE, Suzuki A, Hori T, Oyama T, Morikawa K, Cheeseman IM, Fukagawa T. CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. Cell 2012; 148:487-501; PMID:22304917; http://dx.doi.org/10.1016/j.cell.2011.11.061
   PubMed Web of Science ®Google Scholar
• Garcia MA, Vardy L, Koonrugsa N, Toda T. Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpoint. EMBO J 2001; 20:3389-401; PMID:11432827; http://dx.doi.org/10.1093/emboj/20.13.3389
   PubMed Web of Science ®Google Scholar
• King MC, Drivas TG, Blobel G. A network of nuclear envelope membrane proteins linking centromeres to microtubules. Cell 2008; 134:427-38; PMID:18692466; http://dx.doi.org/10.1016/j.cell.2008.06.022
   PubMed Web of Science ®Google Scholar
• Chen ES, Zhang K, Nicolas E, Cam HP, Zofall M, Grewal SI. Cell cycle control of centromeric repeat transcription and heterochromatin assembly. Nature 2008; 451:734-7; PMID:18216783; http://dx.doi.org/10.1038/nature06561
   PubMed Web of Science ®Google Scholar
• Lu J, Gilbert DM. Cell cycle regulated transcription of heterochromatin in mammals vs. fission yeast: functional conservation or coincidence? Cell Cycle 2008; 7:1907-10; PMID:18604169; http://dx.doi.org/10.4161/cc.7.13.6206
   PubMed Web of Science ®Google Scholar
• Kloc A, Zaratiegui M, Nora E, Martienssen R. RNA interference guides histone modification during the S phase of chromosomal replication. Curr Biol 2008; 18:490-5; PMID:18394897; http://dx.doi.org/10.1016/j.cub.2008.03.016
   PubMed Web of Science ®Google Scholar
• Li MH, Ito D, Sanada M, Odani T, Hatori M, Iwase M, Nagumo M. Effect of 5-fluorouracil on G1 phase cell cycle regulation in oral cancer cell lines. Oral Oncol 2004; 40:63-70; PMID:14662417; http://dx.doi.org/10.1016/S1368-8375(03)00136-2
   PubMed Web of Science ®Google Scholar
• Aygün O, Grewal SI. Assembly and functions of heterochromatin in the fission yeast genome. Cold Spring Harb Symp Quant Biol 2010; 75:259-67; PMID:21502415; http://dx.doi.org/10.1101/sqb.2010.75.055
   PubMedGoogle Scholar
• Bühler M, Spies N, Bartel DP, Moazed D. TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway. Nat Struct Mol Biol 2008; 15:1015-23; PMID:18776903; http://dx.doi.org/10.1038/nsmb.1481
   PubMed Web of Science ®Google Scholar
• Cam HP, Sugiyama T, Chen ES, Chen X, FitzGerald PC, Grewal SI. Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome. Nat Genet 2005; 37:809-19; PMID:15976807; http://dx.doi.org/10.1038/ng1602
   PubMed Web of Science ®Google Scholar
• Stråfors A, Walfridsson J, Bhuiyan H, Ekwall K. The FUN30 chromatin remodeler, Fft3, protects centromeric and subtelomeric domains from euchromatin formation. PLoS Genet 2011; 7:e1001334; http://dx.doi.org/10.1371/journal.pgen.1001334
   Google Scholar
• Kato H, Goto DB, Martienssen RA, Urano T, Furukawa K, Murakami Y. RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Science 2005; 309:467-9; PMID:15947136; http://dx.doi.org/10.1126/science.1114955
   PubMed Web of Science ®Google Scholar
• Volpe TA, Kidner C, Hall IM, Teng G, Grewal SI, Martienssen RA. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 2002; 297:1833-7; PMID:12193640; http://dx.doi.org/10.1126/science.1074973
   PubMed Web of Science ®Google Scholar
• Debeauchamp JL, Moses A, Noffsinger VJ, Ulrich DL, Job G, Kosinski AM, Partridge JF. Chp1-Tas3 interaction is required to recruit RITS to fission yeast centromeres and for maintenance of centromeric heterochromatin. Mol Cell Biol 2008; 28:2154-66; PMID:18212052; http://dx.doi.org/10.1128/MCB.01637-07
   PubMed Web of Science ®Google Scholar
• Lan F, Zaratiegui M, Villen J, Vaughn MW, Verdel A, Huarte M, Shi Y, Gygi SP, Moazed D, Martienssen RA. S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. Mol Cell 2007; 26:89-101; PMID:17434129; http://dx.doi.org/10.1016/j.molcel.2007.02.023
   PubMed Web of Science ®Google Scholar
• Scott KC, White CV, Willard HF. An RNA polymerase III-dependent heterochromatin barrier at fission yeast centromere 1. PLoS One 2007; 2:e1099; PMID:17971862; http://dx.doi.org/10.1371/journal.pone.0001099
   PubMedGoogle Scholar
• Fahrner JA, Eguchi S, Herman JG, Baylin SB. Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Res 2002; 62:7213-8; PMID:12499261
   PubMed Web of Science ®Google Scholar
• Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004; 4:143-53; PMID:14732866; http://dx.doi.org/10.1038/nrc1279
   PubMed Web of Science ®Google Scholar
• Manuyakorn A, Paulus R, Farrell J, Dawson NA, Tze S, Cheung-Lau G, Hines OJ, Reber H, Seligson DB, Horvath S, et al. Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704. J Clin Oncol 2010; 28:1358-65; PMID:20142597; http://dx.doi.org/10.1200/JCO.2009.24.5639
   PubMed Web of Science ®Google Scholar
• Grewal SI, Jia S. Heterochromatin revisited. Nat Rev Genet 2007; 8:35-46; PMID:17173056; http://dx.doi.org/10.1038/nrg2008
   PubMed Web of Science ®Google Scholar
• Takahashi K, Takayama Y, Masuda F, Kobayashi Y, Saitoh S. Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle. Philos Trans R Soc Lond B Biol Sci 2005; 360:595-606; PMID:15897182; http://dx.doi.org/10.1098/rstb.2004.1614
   PubMed Web of Science ®Google Scholar
• Uhlmann F. Chromosome cohesion and segregation in mitosis and meiosis. Curr Opin Cell Biol 2001; 13:754-61; PMID:11698193; http://dx.doi.org/10.1016/S0955-0674(00)00279-9
   PubMed Web of Science ®Google Scholar
• Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell 2006; 127:983-97; PMID:17129783; http://dx.doi.org/10.1016/j.cell.2006.09.039
   PubMed Web of Science ®Google Scholar
• Niwa O, Matsumoto T, Chikashige Y, Yanagida M. Characterization of Schizosaccharomyces pombe minichromosome deletion derivatives and a functional allocation of their centromere. EMBO J 1989; 8:3045-52; PMID:2583093
   PubMed Web of Science ®Google Scholar
• Ekwall K, Nimmo ER, Javerzat JP, Borgstrom B, Egel R, Cranston G, Allshire R. Mutations in the fission yeast silencing factors clr4+ and rik1+ disrupt the localisation of the chromo domain protein Swi6p and impair centromere function. J Cell Sci 1996; 109:2637-48; PMID:8937982
   PubMed Web of Science ®Google Scholar
• Cha HJ, Byrom M, Mead PE, Ellington AD, Wallingford JB, Marcotte EM. Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol 2012; 10:e1001379; PMID:22927795; http://dx.doi.org/10.1371/journal.pbio.1001379
   PubMedGoogle Scholar
• Shih C, Teicher BA. Cryptophycins: a novel class of potent antimitotic antitumor depsipeptides. Curr Pharm Des 2001; 7:1259-76; PMID:11472266; http://dx.doi.org/10.2174/1381612013397474
   PubMed Web of Science ®Google Scholar
• Burris HA, 3rd. Docetaxel in combination with fluorouracil for advanced solid tumors. Oncology (Williston Park) 1997; 11:50-2; PMID:9364544
   PubMedGoogle Scholar
• Zhou Y, Lin J, Johnson RG Jr. KOS-862 (epothilone D) and 5′-deoxy-5-fluorouridine or 5-fluorouracil in human breast cancer cells: marked synergistic antitumor effects and induction of thymidine phosphorylase expression. Proc Am Assoc Cancer Res 2004; 45:Abstr 5429.
   Google Scholar
• Kniola B, O’Toole E, McIntosh JR, Mellone B, Allshire R, Mengarelli S, Hultenby K, Ekwall K. The domain structure of centromeres is conserved from fission yeast to humans. Mol Biol Cell 2001; 12:2767-75; PMID:11553715; http://dx.doi.org/10.1091/mbc.12.9.2767
   PubMed Web of Science ®Google Scholar
• Bernstein E, Allis CD. RNA meets chromatin. Genes Dev 2005; 19:1635-55; PMID:16024654; http://dx.doi.org/10.1101/gad.1324305
   PubMed Web of Science ®Google Scholar
• Cam HP, Chen ES, Grewal SI. Transcriptional scaffolds for heterochromatin assembly. Cell 2009; 136:610-4; PMID:19239883; http://dx.doi.org/10.1016/j.cell.2009.02.004
   PubMed Web of Science ®Google Scholar
• Lantermann AB, Straub T, Stralfors A, Yuan GC, Ekwall K, Korber P. Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae. Nat Struct Mol Biol 2010; 17:251-7; PMID:20118936; http://dx.doi.org/10.1038/nsmb.1741
   PubMed Web of Science ®Google Scholar