Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma

References

• Nyormoi O, Bar-Eli M. Transcriptional regulation of metastasis-related genes in human melanoma. Clin Exp Metastasis 2003; 20:251-63; PMID:12741683; http://dx.doi.org/10.1023/A: 1022991302172
   PubMed Web of Science ®Google Scholar
• Eckert D, Buhl S, Weber S, Jager R, Schorle H. The AP-2 family of transcription factors. Genome Biol 2005; 6:246; PMID:16420676; http://dx.doi.org/10.1186/gb-2005-6-13-246
   PubMed Web of Science ®Google Scholar
• Wenke AK, Bosserhoff AK. Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development. FEBS J 2010; 277:894-902; PMID:20050923; http://dx.doi.org/10.1111/j.1742-4658.2009.07509.x
   PubMed Web of Science ®Google Scholar
• Hilger-Eversheim K, Moser M, Schorle H, Buettner R. Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control. Gene 2000; 260:1-12; PMID:11137286; http://dx.doi.org/10.1016/S0378-1119(00)00454-6
   PubMed Web of Science ®Google Scholar
• Huang S, Jean D, Luca M, Tainsky MA, Bar-Eli M. Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis. EMBO J 1998; 17:4358-69; PMID:9687504; http://dx.doi.org/10.1093/emboj/17.15.4358
   PubMed Web of Science ®Google Scholar
• Tellez C, McCarty M, Ruiz M, Bar-Eli M. Loss of activator protein-2alpha results in overexpression of protease-activated receptor-1 and correlates with the malignant phenotype of human melanoma. J Biol Chem 2003; 278:46632-42; PMID:12975361; http://dx.doi.org/10.1074/jbc.M309159200
   PubMed Web of Science ®Google Scholar
• Berger AJ, Davis DW, Tellez C, Prieto VG, Gershenwald JE, Johnson MM, Rimm DL, Bar-Eli M. Automated quantitative analysis of activator protein-2alpha subcellular expression in melanoma tissue microarrays correlates with survival prediction. Cancer Res 2005; 65:11185-92; PMID:16322269; http://dx.doi.org/10.1158/0008-5472.CAN-05-2300
   PubMed Web of Science ®Google Scholar
• Brewer S, Feng W, Huang J, Sullivan S, Williams T. Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects. Dev Biol 2004; 267:135-52; PMID:14975722; http://dx.doi.org/10.1016/j.ydbio.2003.10.039
   PubMed Web of Science ®Google Scholar
• Knight RD, Javidan Y, Nelson S, Zhang T, Schilling T. Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest development. Dev Dyn 2004; 229:87-98; PMID:14699580; http://dx.doi.org/10.1002/dvdy.10494
   PubMed Web of Science ®Google Scholar
• O'Brien EK, d'Alencon SC, Bonde G, Li W, Schoenebeck J, Allende ML, Gelb BD, Yelon D, Eisen JS, Cornell RA. Transcription factor Ap-2alpha is necessary for development of embryonic melanophores, autonomic neurons and pharyngeal skeleton in zebrafish. Dev Biol 2004; 265:246-61; PMID:14697367; http://dx.doi.org/10.1016/j.ydbio.2003.09.029
   PubMed Web of Science ®Google Scholar
• Van Otterloo E, Li W, Bonde G, Day KM, Hsu MY, Cornell RA. Differentiation of zebrafish melanophores depends on transcription factors AP2 α and AP2 epsilon. PLoS Genet 2010; 6:e1001122; PMID:20862309; http://dx.doi.org/10.1371/journal.pgen.1001122
   PubMedGoogle Scholar
• Milunsky JM, Maher TM, Zhao G, Wang Z, Mulliken JB, Chitayat D, Clemens M, Stalker HJ, Bauer M, Burch M, et al. Genotype-phenotype analysis of the branchio-oculo-facial syndrome. Am J Med Genet A 2011; 155A:22-32; PMID:21204207; http://dx.doi.org/10.1002/ajmg.a.33783
   PubMed Web of Science ®Google Scholar
• Douglas DB, Akiyama Y, Carraway H, Belinsky SA, Esteller M, Gabrielson E, Weitzman S, Williams T, Herman JG, Baylin SB. Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer. Cancer Res 2004; 64:1611-20; PMID:14996719; http://dx.doi.org/10.1158/0008-5472.CAN-0318-2
   PubMed Web of Science ®Google Scholar
• Makhov PB, Golovine KV, Kutikov A, Canter DJ, Rybko VA, Roshchin DA, Matveev VB, Uzzo RG, Kolenko VM. Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells. Carcinogenesis 2011; 32:1773-81; PMID:21940908; http://dx.doi.org/10.1093/carcin/bgr212
   PubMed Web of Science ®Google Scholar
• Zeng L, Jarrett C, Brown K, Gillespie KM, Holly JM, Perks CM. Insulin-like growth factor binding protein-3 (IGFBP-3) plays a role in the anti-tumorigenic effects of 5-Aza-2′-deoxycytidine (AZA) in breast cancer cells. Exp Cell Res 2013; 319:2282-95; PMID:23810988; http://dx.doi.org/10.1016/j.yexcr.2013.06.011
   PubMed Web of Science ®Google Scholar
• Penna E, Orso F, Cimino D, Vercellino I, Grassi E, Quaglino E, Turco E, Taverna D. miR-214 coordinates melanoma progression by upregulating ALCAM through TFAP2 and miR-148b downmodulation. Cancer Res 2013; 73:4098-111; PMID:23667173; http://dx.doi.org/10.1158/0008-5472.CAN-12-3686
   PubMed Web of Science ®Google Scholar
• Melnikova VO, Dobroff AS, Zigler M, Villares GJ, Braeuer RR, Wang H, Huang L, Bar-Eli M. CREB inhibits AP-2alpha expression to regulate the malignant phenotype of melanoma. PLoS One 2010; 5:e12452; PMID:20805990; http://dx.doi.org/10.1371/journal.pone.0012452
   PubMedGoogle Scholar
• Livingstone E, Zimmer L, Piel S, Schadendorf D. PLX4032: does it keep its promise for metastatic melanoma treatment? Expert Opin Investing Drugs 2010; 19:1439-49; PMID:20942773; http://dx.doi.org/10.1517/13543784.2010.527945
   PubMed Web of Science ®Google Scholar
• Solit DB, Rosen N. Resistance to BRAF inhibition in melanomas. N Engl J Med 2011; 364:772-4; PMID:21345109; http://dx.doi.org/10.1056/NEJMcibr1013704
   PubMed Web of Science ®Google Scholar
• Gollob JA, Sciambi CJ, Peterson BL, Richmond T, Thoreson M, Moran K, Dressman HK, Jelinek J, Issa JP. Phase I trial of sequential low-dose 5-aza-2′-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma. Clin Cancer Res 2006; 12:4619-27; PMID:16899610; http://dx.doi.org/10.1158/1078-0432.CCR-06-0883
   PubMed Web of Science ®Google Scholar
• Li LC, Dahiya R. MethPrimer: designing primers for methylation PCRs. Bioinformatics 2002; 18:1427-31; PMID:12424112; http://dx.doi.org/10.1093/bioinformatics/18.11.1427
   PubMed Web of Science ®Google Scholar