AKAP350C targets to mitochondria via a novel amphipathic alpha helical domain

References

• Horbinski C, Chu CT. Kinase signaling cascades in the mitochondrion: a matter of life or death. Free Radic Biol Med 2005; 38:2-11; PMID: 15589366; http://dx.doi.org/10.1016/j.freeradbiomed.2004.09.030
   PubMed Web of Science ®Google Scholar
• Gunter TE, Buntinas L, Sparagna G, Eliseev R, Gunter K. Mitochondrial calcium transport: mechanisms and functions. Cell Calcium 2000; 28:285-96; PMID: 11115368; http://dx.doi.org/10.1054/ceca.2000.0168
   PubMed Web of Science ®Google Scholar
• Dorn GW, 2nd, Scorrano L. Two close, too close: sarcoplasmic reticulum-mitochondrial crosstalk and cardiomyocyte fate. Circ Res 2010; 107:689-99; PMID: 20847324; http://dx.doi.org/10.1161/CIRCRESAHA.110.225714
   PubMed Web of Science ®Google Scholar
• Carlucci A, Lignitto L, Feliciello A. Control of mitochondria dynamics and oxidative metabolism by cAMP, AKAPs and the proteasome. Trends Cell Biol 2008; 18:604-13; PMID: 18951795; http://dx.doi.org/10.1016/j.tcb.2008.09.006
   PubMed Web of Science ®Google Scholar
• Fulda S, Gorman AM, Hori O, Samali A. Cellular stress responses: cell survival and cell death. Int J Cell Biol 2010; 2010:214074; PMID: 20182529
   PubMedGoogle Scholar
• Nishida H, Sato T, Ogura T, Nakaya H. New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: mitochondrial ion channels and cardioprotection. J Pharmacol Sci 2009; 109:341-7; PMID: 19270424; http://dx.doi.org/10.1254/jphs.08R24FM
   PubMed Web of Science ®Google Scholar
• Chen H, Chan DC. Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases. Hum Mol Genet 2009; 18:R169-76; PMID: 19808793; http://dx.doi.org/10.1093/hmg/ddp326
   PubMed Web of Science ®Google Scholar
• Zuchner S, Mersiyanova IV, Muglia M, Bissar-Tadmouri N, Rochelle J, Dadali EL, Zappia M, Nelis E, Patitucci A, Senderek J, Parman Y, et al. Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat Genet 2004; 36:449-51; PMID: 15064763; http://dx.doi.org/10.1038/ng1341
   PubMed Web of Science ®Google Scholar
• Eiberg H, Kjer B, Kjer P, Rosenberg T. Dominant optic atrophy (OPA1) mapped to chromosome 3q region. I. Linkage analysis. Hum Mol Genet 1994; 3:977-80; PMID: 7951248; http://dx.doi.org/10.1093/hmg/3.6.977
   PubMed Web of Science ®Google Scholar
• Liesa M, Palacin M, Zorzano A. Mitochondrial dynamics in mammalian health and disease. Physiol Rev 2009; 89:799-845; PMID: 19584314; http://dx.doi.org/10.1152/physrev.00030.2008
   PubMed Web of Science ®Google Scholar
• Rambold AS, Lippincott-Schwartz J. Mechanisms of mitochondria and autophagy crosstalk. Cell Cycle 2011; 10:4032-8; PMID: 22101267; http://dx.doi.org/10.4161/cc.10.23.18384
   PubMed Web of Science ®Google Scholar
• Chang CR, Blackstone C. Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology. J Biol Chem 2007; 282:21583-7; PMID: 17553808; http://dx.doi.org/10.1074/jbc.C700083200
   PubMed Web of Science ®Google Scholar
• Chen KH, Guo X, Ma D, Guo Y, Li Q, Yang D, Li P, Qiu X, Wen S, Xiao RP, Tang J. Dysregulation of HSG triggers vascular proliferative disorders. Nat Cell Biol 2004; 6:872-83; PMID: 15322553; http://dx.doi.org/10.1038/ncb1161
   PubMed Web of Science ®Google Scholar
• Theurkauf WE, Vallee RB. Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2. J Biol Chem 1982; 257:3284-90; PMID: 6277931
   PubMed Web of Science ®Google Scholar
• Lohmann SM, DeCamilli P, Einig I, Walter U. High-affinity binding of the regulatory subunit (RII) of cAMP-dependent protein kinase to microtubule-associated and other cellular proteins. Proc Natl Acad Sci U S A 1984; 81:6723-7; PMID: 6093118; http://dx.doi.org/10.1073/pnas.81.21.6723
   PubMed Web of Science ®Google Scholar
• Wong W, Scott JD. AKAP signalling complexes: focal points in space and time. Nat Rev Mol Cell Biol 2004; 5:959-70; PMID: 15573134; http://dx.doi.org/10.1038/nrm1527
   PubMed Web of Science ®Google Scholar
• Carnegie GK, Means CK, Scott JD. A-kinase anchoring proteins: from protein complexes to physiology and disease. IUBMB Life 2009; 61:394-406; PMID: 19319965; http://dx.doi.org/10.1002/iub.168
   PubMed Web of Science ®Google Scholar
• Welch EJ, Jones BW, Scott JD. Networking with AKAPs: context-dependent regulation of anchored enzymes. Mol Interv 2010; 10:86-97; PMID: 20368369; http://dx.doi.org/10.1124/mi.10.2.6
   PubMed Web of Science ®Google Scholar
• Ma Y, Taylor SS. A molecular switch for targeting between endoplasmic reticulum (ER) and mitochondria: conversion of a mitochondria-targeting element into an ER-targeting signal in DAKAP1. J Biol Chem 2008; 283:11743-51; PMID: 18287098; http://dx.doi.org/10.1074/jbc.M710494200
   PubMed Web of Science ®Google Scholar
• Rogne M, Stokka AJ, Tasken K, Collas P, Kuntziger T. Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network. Hum Mol Genet 2009; 18:978-87; PMID: 19074462
   PubMed Web of Science ®Google Scholar
• Perrino C, Feliciello A, Schiattarella GG, Esposito G, Guerriero R, Zaccaro L, Del Gatto A, Saviano M, Garbi C, Carangi R, et al. AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress. Cardiovasc Res 2010; 88:101-10; PMID: 20511238; http://dx.doi.org/10.1093/cvr/cvq155
   PubMed Web of Science ®Google Scholar
• Affaitati A, Cardone L, de Cristofaro T, Carlucci A, Ginsberg MD, Varrone S, Gottesman ME, Avvedimento EV, Feliciello A. Essential role of A-kinase anchor protein 121 for cAMP signaling to mitochondria. J Biol Chem 2003; 278:4286-94; PMID: 12427737; http://dx.doi.org/10.1074/jbc.M209941200
   PubMed Web of Science ®Google Scholar
• Bui M, Gilady SY, Fitzsimmons RE, Benson MD, Lynes EM, Gesson K, Alto NM, Strack S, Scott JD, Simmen T. Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties. J Biol Chem 2010; 285:31590-602; PMID: 20670942; http://dx.doi.org/10.1074/jbc.M110.101584
   PubMed Web of Science ®Google Scholar
• Schmidt PH, Dransfield DT, Claudio JO, Hawley RG, Trotter KW, Milgram SL, Goldenring JR. AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes. J Biol Chem 1999; 274:3055-66; PMID: 9915845; http://dx.doi.org/10.1074/jbc.274.5.3055
   PubMed Web of Science ®Google Scholar
• Witczak O, Skalhegg BS, Keryer G, Bornens M, Tasken K, Jahnsen T, Orstavik S. Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450. Embo J 1999; 18:1858-68; PMID: 10202149; http://dx.doi.org/10.1093/emboj/18.7.1858
   PubMed Web of Science ®Google Scholar
• Takahashi M, Shibata H, Shimakawa M, Miyamoto M, Mukai H, Ono Y. Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus. J Biol Chem 1999; 274:17267-74; PMID: 10358086; http://dx.doi.org/10.1074/jbc.274.24.17267
   PubMed Web of Science ®Google Scholar
• Shanks RA, Steadman BT, Schmidt PH, Goldenring JR. AKAP350 at the Golgi apparatus. I. Identification of a distinct Golgi apparatus targeting motif in AKAP350. J Biol Chem 2002; 277:40967-72; PMID: 12163481; http://dx.doi.org/10.1074/jbc.M203307200
   PubMed Web of Science ®Google Scholar
• Gillingham AK, Munro S. The PACT domain, a conserved centrosomal targeting motif in the coiled-coil proteins AKAP450 and pericentrin. EMBO Rep 2000; 1:524-9; PMID: 11263498; http://dx.doi.org/10.1093/embo-reports/kvd105
   PubMed Web of Science ®Google Scholar
• Otera H, Wang C, Cleland MM, Setoguchi K, Yokota S, Youle RJ, Mihara K. Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells. J Cell Biol 2010; 191:1141-58; PMID: 21149567; http://dx.doi.org/10.1083/jcb.201007152
   PubMed Web of Science ®Google Scholar
• Otera H, Mihara K. Discovery of the membrane receptor for mitochondrial fission GTPase Drp1. Small GTPases 2011; 2:167-72; PMID: 21776419; http://dx.doi.org/10.4161/sgtp.2.3.16486
   PubMedGoogle Scholar
• Santel A, Frank S, Gaume B, Herrler M, Youle RJ, Fuller MT. Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells. J Cell Sci 2003; 116:2763-74; PMID: 12759376; http://dx.doi.org/10.1242/jcs.00479
   PubMed Web of Science ®Google Scholar
• Pich S, Bach D, Briones P, Liesa M, Camps M, Testar X, Palacin M, Zorzano A. The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system. Hum Mol Genet 2005; 14:1405-15; PMID: 15829499; http://dx.doi.org/10.1093/hmg/ddi149
   PubMed Web of Science ®Google Scholar
• Gelb BD, Adams V, Jones SN, Griffin LD, MacGregor GR, McCabe ER. Targeting of hexokinase 1 to liver and hepatoma mitochondria. Proc Natl Acad Sci U S A 1992; 89:202-6; PMID: 1309605; http://dx.doi.org/10.1073/pnas.89.1.202
   PubMed Web of Science ®Google Scholar
• Sui D, Wilson JE. Structural determinants for the intracellular localization of the isozymes of mammalian hexokinase: intracellular localization of fusion constructs incorporating structural elements from the hexokinase isozymes and the green fluorescent protein. Arch Biochem Biophys 1997; 345:1-11-25; http://dx.doi.org/10.1006/abbi.1997.0241
   Web of Science ®Google Scholar
• Ma Y, Taylor S. A 15-residue bifunctional element in D-AKAP1 is required for both endoplasmic reticulum and mitochondrial targeting. J Biol Chem 2002; 277:27328-36; PMID: 11994283; http://dx.doi.org/10.1074/jbc.M201421200
   PubMed Web of Science ®Google Scholar
• Youle RJ, van der Bliek AM. Mitochondrial fission, fusion, and stress. Science 2012; 337:1062-5; PMID: 22936770; http://dx.doi.org/10.1126/science.1219855
   PubMed Web of Science ®Google Scholar
• Kolobova E, Efimov A, Kaverina I, Rishi AK, Schrader JW, Ham AJ, Larocca MC, Goldenring JR. Microtubule-dependent association of AKAP350A and CCAR1 with RNA stress granules. Exp Cell Res 2009; 315:542-55; PMID: 19073175; http://dx.doi.org/10.1016/j.yexcr.2008.11.011
   PubMed Web of Science ®Google Scholar
• Mason TA, Kolobova E, Liu J, Roland JT, Chiang C, Goldenring JR. Darinaparsin is a multivalent chemotherapeutic which induces incomplete stress response with disruption of microtubules and Shh signaling. PLoS One 2011; 6:e27699; PMID: 22110729; http://dx.doi.org/10.1371/journal.pone.0027699
   PubMedGoogle Scholar
• Chen H, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, Chan DC. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 2003; 160:189-200; PMID: 12527753; http://dx.doi.org/10.1083/jcb.200211046
   PubMed Web of Science ®Google Scholar
• Joseph AM, Joanisse DR, Baillot RG, Hood DA. Mitochondrial dysregulation in the pathogenesis of diabetes: potential for mitochondrial biogenesis-mediated interventions. Exp Diabetes Res 2012; 2012:642038; PMID: 22203837; http://dx.doi.org/10.1155/2012/642038
   PubMed Web of Science ®Google Scholar