935
Views
4
CrossRef citations to date
0
Altmetric
Addendum

Impaired striatal function in Huntington's disease is due to aberrant p75NTR signaling

&
Article: e968482 | Received 15 Aug 2014, Accepted 18 Sep 2014, Published online: 03 Nov 2014

References

  • The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington“s disease chromosomes. Cell 1993; 72:971-83; PMID:8458085; http://dx.doi.org/10.1016/0092-8674(93)90585-E
  • Raymond LA, Andre VM, Cepeda C, Gladding CM, Milnerwood AJ, Levine MS. Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function. Neuroscience 2011; 198:252-73; PMID:21907762; http://dx.doi.org/10.1016/j.neuroscience.2011.08.052
  • Reiner A, Albin RL, Anderson KD, D'Amato CJ, Penney JB, Young AB. Differential loss of striatal projection neurons in Huntington disease. Proc Natl Acad Sci USA 1988; 85:5733-7; PMID:2456581; http://dx.doi.org/10.1073/pnas.85.15.5733
  • Alexander GE, Crutcher MD. Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 1990; 13:266-71; PMID:1695401; http://dx.doi.org/10.1016/0166-2236(90)90107-L
  • Gerfen CR, Surmeier DJ. Modulation of Striatal Projection Systems by Dopamine. Annu Rev Neurosci 2011; 34:441-66; PMID:21469956; http://dx.doi.org/10.1146/annurev-neuro-061010-113641
  • Zuccato C, Valenza M, Cattaneo E. Molecular mechanisms and potential therapeutical targets in Huntington's disease. Physiol Rev 2010; 90:905-81; PMID:20664076; http://dx.doi.org/10.1152/physrev.00041.2009
  • Zuccato C, Cattaneo E. Role of brain-derived neurotrophic factor in Huntington's disease. Prog Neurobiol 2007; 81:294-330; PMID:17379385; http://dx.doi.org/10.1016/j.pneurobio.2007.01.003
  • Altar CA, Cai N, Bliven T, Juhasz M, Conner JM, Acheson AL, Lindsay RM, Wiegand SJ. Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature 1997; 389:856-60; PMID:9349818; http://dx.doi.org/10.1038/39885
  • Kress GJ, Yamawaki N, Wokosin DL, Wickersham IR, Shepherd GMG, Surmeier DJ. Convergent cortical innervation of striatal projection neurons. Nat Neurosci 2013; 16:665-7; PMID:23666180; http://dx.doi.org/10.1038/nn.3397
  • Wall NR, La Parra De M, Callaway EM, Kreitzer AC. Differential Innervation of Direct- and Indirect-Pathway Striatal Projection Neurons. Neuron 2013; PMID:23810541
  • Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, MacDonald ME, Friedlander RM, Silani V, Hayden MR, et al. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 2001; 293:493-8; PMID:11408619; http://dx.doi.org/10.1126/science.1059581
  • Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu X-H, Tao J, Yamazaki I, Li S-H, Sun YE, et al. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice. J Neurosci 2008; 28:6182-95; PMID:18550760; http://dx.doi.org/10.1523/JNEUROSCI.0857-08.2008
  • Pfister C, Tatabiga MS, Roser F. Selection of suitable reference genes for quantitative real-time polymerase chain reaction in human meningiomas and arachnoidea. BMC Res Notes 2011; 4:275; PMID:21806841; http://dx.doi.org/10.1186/1756-0500-4-275
  • Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, et al. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 2004; 118:127-38; PMID:15242649; http://dx.doi.org/10.1016/j.cell.2004.06.018
  • Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Annu Rev Neurosci 1995; 18:223-53; PMID:7605062; http://dx.doi.org/10.1146/annurev.ne.18.030195.001255
  • Dechant G, Barde Y-A. The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system. Nat Neurosci 2002; 5:1131-6; PMID:12404007; http://dx.doi.org/10.1038/nn1102-1131
  • Brito V, Puigdellívol M, Giralt A, del Toro D, Alberch J, Ginés S. Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies. Cell Death Dis 2013; 4:e595; PMID:23598407; http://dx.doi.org/10.1038/cddis.2013.116
  • Todd D, Gowers I, Dowler SJ, Wall MD, McAllister G, Fischer DF, Dijkstra S, Fratantoni SA, van de Bospoort R, Veenman-Koepke J, et al. A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington's Disease. PLoS ONE 2014; 9:e87923; PMID:24503862; http://dx.doi.org/10.1371/journal.pone.0087923
  • Simmons DA, Belichenko NP, Yang T, Condon C, Monbureau M, Shamloo M, Jing D, Massa SM, Longo FM. A Small Molecule TrkB Ligand Reduces Motor Impairment and Neuropathology in R6/2 and BACHD Mouse Models of Huntington's Disease. J of Neurosci 2013; 33:18712-27; PMID:24285878; http://dx.doi.org/10.1523/JNEUROSCI.1310-13.2013
  • Milnerwood AJ, Gladding CM, Pouladi MA, Kaufman AM, Hines RM, Boyd JD, Ko RWY, Vasuta OC, Graham RK, Hayden MR, et al. Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice. Neuron 2010; 65:178-90; PMID:20152125; http://dx.doi.org/10.1016/j.neuron.2010.01.008
  • Ning K, Pei L, Liao M, Liu B, Zhang Y, Jiang W, Mielke JG, Li L, Chen Y, El-Hayek YH, et al. Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN. J Neurosci 2004; 24:4052-60; PMID:15102920; http://dx.doi.org/10.1523/JNEUROSCI.5449-03.2004
  • Hopkins BD, Hodakoski C, Barrows D, Mense SM, Parsons RE. PTEN function: the long and the short of it. Trends Biochem Sci 2014; 39:183-90; PMID: 24656806; http://dx.doi.org/10.1016/j.tibs.2014.02.006
  • MD DJJ, MD PKS, MD PJS. Cancer incidence in patients with polyglutamine diseases: a population-based study in Sweden. Lancet Oncol 2012; 13:642-8; PMID:22503213; http://dx.doi.org/10.1016/S1470-2045(12)70132-8