Sox2: A multitasking networker

References

• Masui S, Nakatake Y, Toyooka Y, Shimosato D, Yagi R, Takahashi K, Okochi H, Okuda A, Matoba R, Sharov AA, et al. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 2007; 9:625-35; PMID:17515932; http://dx.doi.org/10.1038/ncb1589
   PubMed Web of Science ®Google Scholar
• Bylund M, Andersson E, Novitch BG, Muhr J. Vertebrate neurogenesis is counteracted by Sox1-3 activity. Nat Neurosc 2003; 6:1162-8; PMID:14517545; http://dx.doi.org/10.1038/nn1131
   PubMed Web of Science ®Google Scholar
• Graham V, Khudyakov J, Ellis P, Pevny L. SOX2 functions to maintain neural progenitor identity. Neuron 2003; 39:749-65; PMID:12948443; http://dx.doi.org/10.1016/S0896-6273(03)00497-5
   PubMed Web of Science ®Google Scholar
• Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126:663-76; PMID: 16904174; http://dx.doi.org/10.1016/j.cell.2006.07.024
   PubMed Web of Science ®Google Scholar
• Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 2003; 17:126-40; PMID:12514105; http://dx.doi.org/10.1101/gad.224503
   PubMed Web of Science ®Google Scholar
• Zhao S, Nichols J, Smith AG, Li M. SoxB transcription factors specify neuroectodermal lineage choice in ES cells. Mol Cell Neurosci 2004; 27:332-42; PMID:15519247; http://dx.doi.org/10.1016/j.mcn.2004.08.002
   PubMed Web of Science ®Google Scholar
• Thomson M, Liu SJ, Zou LN, Smith Z, Meissner A, Ramanathan S. Pluripotency factors in embryonic stem cells regulate differentiation into germ layers. Cell 2011; 145:875-89; PMID:21663792; http://dx.doi.org/10.1016/j.cell.2011.05.017
   PubMed Web of Science ®Google Scholar
• Ferri AL, Cavallaro M, Braida D, Di Cristofano A, Canta A, Vezzani A, Ottolenghi S, Pandolfi PP, Sala M, DeBiasi S, et al. Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development 2004; 131:3805-19; PMID:15240551; http://dx.doi.org/10.1242/dev.01204
   PubMed Web of Science ®Google Scholar
• Kuwabara T, Hsieh J, Muotri A, Yeo G, Warashina M, Lie DC, Moore L, Nakashima K, Asashima M, Gage FH. Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nat Neurosci 2009; 12:1097-105; PMID:19701198; http://dx.doi.org/10.1038/nn.2360
   PubMed Web of Science ®Google Scholar
• Muotri AR, Chu VT, Marchetto MC, Deng W, Moran JV, Gage FH. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature 2005; 435:903-10; PMID:15959507; http://dx.doi.org/10.1038/nature03663
   PubMed Web of Science ®Google Scholar
• Wegner M. SOX after SOX: SOXession regulates neurogenesis. Genes Dev 2011; 25:2423-8; PMID:22156204; http://dx.doi.org/10.1101/gad.181487.111
   PubMed Web of Science ®Google Scholar
• Bergsland M, Ramskold D, Zaouter C, Klum S, Sandberg R, Muhr J. Sequentially acting Sox transcription factors in neural lineage development. Genes Dev 2011; 25:2453-64; PMID:22085726; http://dx.doi.org/10.1101/gad.176008.111
   PubMed Web of Science ®Google Scholar
• Engelen E, Akinci U, Bryne JC, Hou J, Gontan C, Moen M, Szumska D, Kockx C, van Ijcken W, Dekkers DH, et al. Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes. Nat Genet 2011; 43:607-11; PMID:21532573; http://dx.doi.org/10.1038/ng.825
   PubMed Web of Science ®Google Scholar
• Cimadamore F, Amador-Arjona A, Chen C, Huang CT, Terskikh AV. SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors. Proc Nat Acad Sci U S A 2013; 110:E3017-26; PMID:23884650; http://dx.doi.org/10.1073/pnas.1220176110
   PubMedGoogle Scholar
• Hoffmann SA, Hos D, Küspert M, Lang RA, Lovell-Badge R, Wegner M, Reiprich S. Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes. Development 2014; 141:39-50; PMID: 24257626; http://dx.doi.org/10.1242/dev.098418
   PubMed Web of Science ®Google Scholar
• Taranova OV, Magness ST, Fagan BM, Wu Y, Surzenko N, Hutton SR, Pevny LH. SOX2 is a dose-dependent regulator of retinal neural progenitor competence. Genes Dev 2006; 20:1187-202; PMID:16651659; http://dx.doi.org/10.1101/gad.1407906
   PubMed Web of Science ®Google Scholar
• Cavallaro M, Mariani J, Lancini C, Latorre E, Caccia R, Gullo F, Valotta M, DeBiasi S, Spinardi L, Ronchi A, et al. Impaired generation of mature neurons by neural stem cells from hypomorphic Sox2 mutants. Development 2008; 135:541-57; PMID:18171687; http://dx.doi.org/10.1242/dev.010801
   PubMed Web of Science ®Google Scholar
• Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, Bartsch U, Wegner M. Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev 2002; 16:165-70; PMID:11799060; http://dx.doi.org/10.1101/gad.215802
   PubMed Web of Science ®Google Scholar
• Hornig J, Fröb F, Vogl MR, Hermans-Borgmeyer I, Tamm ER, Wegner M. The transcription factors Sox10 and Myrf define an essential regulatory network module in differentiating oligodendrocytes. PLoS Genet 2013; 9:e1003907; PMID:24204311; http://dx.doi.org/10.1371/journal.pgen.1003907
   PubMed Web of Science ®Google Scholar
• Yu Y, Chen Y, Kim B, Wang H, Zhao C, He X, Liu L, Liu W, Wu LM, Mao M, et al. Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell 2013; 152:248-61; PMID:23332759; http://dx.doi.org/10.1016/j.cell.2012.12.006
   PubMed Web of Science ®Google Scholar
• Emery B, Agalliu D, Cahoy JD, Watkins TA, Dugas JC, Mulinyawe SB, Ibrahim A, Ligon KL, Rowitch DH, Barres BA. Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell 2009; 138:172-85; PMID:19596243; http://dx.doi.org/10.1016/j.cell.2009.04.031
   PubMed Web of Science ®Google Scholar
• Vogl MR, Reiprich S, Küspert M, Kosian T, Schrewe H, Nave KA, Wegner M. Sox10 Cooperates with the Mediator Subunit 12 during Terminal Differentiation of Myelinating Glia. J Neurosci 2013; 33:6679-90; PMID:23575864; http://dx.doi.org/10.1523/JNEUROSCI.5178-12.2013
   PubMed Web of Science ®Google Scholar
• Fang X, Yoon JG, Li L, Yu W, Shao J, Hua D, Zheng S, Hood L, Goodlett DR, Foltz G, et al. The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis. BMC Genomics 2011; 12:11; PMID:21211035; http://dx.doi.org/10.1186/1471-2164-12-11
   PubMed Web of Science ®Google Scholar