Role of histone deacetylase 9 in regulating adipogenic differentiation and high fat diet-induced metabolic disease

References

• Berry R, Jeffery E, Rodeheffer MS. Weighing in on Adipocyte Precursors. Cell Metab 2014; 19:8-20; PMID:24239569; http://dx.doi.org/10.1016/j.cmet.2013.10.003
   PubMed Web of Science ®Google Scholar
• Joe AW, Yi L, Even Y, Vogl AW, Rossi FM. Depot-specific differences in adipogenic progenitor abundance and proliferative response to high-fat diet. Stem Cells 2009; 27:2563-70; PMID:19658193; http://dx.doi.org/10.1002/stem.190
   PubMed Web of Science ®Google Scholar
• Rigamonti A, Brennand K, Lau F, Cowan CA. Rapid cellular turnover in adipose tissue. PLoS One 2011; 6:e17637; PMID:21407813; http://dx.doi.org/10.1371/journal.pone.0017637
   PubMed Web of Science ®Google Scholar
• Spalding KL, Arner E, Westermark PO, Bernard S, Buchholz BA, Bergmann O, Blomqvist L, Hoffstedt J, Näslund E, Britton T, et al. Dynamics of fat cell turnover in humans. Nature 2008; 453:783-7; PMID:18454136; http://dx.doi.org/10.1038/nature06902
   PubMed Web of Science ®Google Scholar
• Lee YH, Petkova AP, Granneman JG. Identification of an adipogenic niche for adipose tissue remodeling and restoration. Cell Metab 2013; 18:355-67; PMID:24011071; http://dx.doi.org/10.1016/j.cmet.2013.08.003
   PubMed Web of Science ®Google Scholar
• Wang QA, Tao C, Gupta RK, Scherer PE. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nat Med 2013; 19:1338-44; PMID:23995282; http://dx.doi.org/10.1038/nm.3324
   PubMed Web of Science ®Google Scholar
• Blüher M. Adipose tissue dysfunction contributes to obesity related metabolic diseases. Best Pract Res Clin Endocrinol Metab 2013; 27:163-77; PMID:23731879; http://dx.doi.org/10.1016/j.beem.2013.02.005
   PubMed Web of Science ®Google Scholar
• Hauner H. Adipose tissue inflammation: are small or large fat cells to blame? Diabetologia 2010; 53:223-5; PMID:19937224; http://dx.doi.org/10.1007/s00125-009-1605-3
   PubMed Web of Science ®Google Scholar
• Hauner H. Secretory factors from human adipose tissue and their functional role. Proc Nutr Soc 2005; 64:163-9; PMID:15960861; http://dx.doi.org/10.1079/PNS2005428
   PubMed Web of Science ®Google Scholar
• Chatterjee TK, Basford JE, Knoll E, Tong WS, Blanco V, Blomkalns AL, Rudich S, Lentsch AB, Hui DY, Weintraub NL. HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding. Diabetes 2014; 63:176-87; PMID:24101673; http://dx.doi.org/10.2337/db13-1148
   PubMedGoogle Scholar
• Cantone I, Fisher AG. Epigenetic programming and reprogramming during development. Nat Struct Mol Biol 2013; 20:282-9; PMID:23463313; http://dx.doi.org/10.1038/nsmb.2489
   PubMed Web of Science ®Google Scholar
• Chatterjee TK, Idelman G, Blanco V, Blomkalns AL, Piegore MG Jr., Weintraub DS, Kumar S, Rajsheker S, Manka D, Rudich SM, et al. Histone deacetylase 9 is a negative regulator of adipogenic differentiation. J Biol Chem 2011; 286:27836-47; PMID:21680747; http://dx.doi.org/10.1074/jbc.M111.262964
   PubMed Web of Science ®Google Scholar
• Chen YH, Yeh FL, Yeh SP, Ma HT, Hung SC, Hung MC, Li LY. Myocyte enhancer factor-2 interacting transcriptional repressor (MITR) is a switch that promotes osteogenesis and inhibits adipogenesis of mesenchymal stem cells by inactivating peroxisome proliferator-activated receptor gamma-2. J Biol Chem 2011; 286:10671-80; PMID:21247904; http://dx.doi.org/10.1074/jbc.M110.199612
   PubMed Web of Science ®Google Scholar
• Sun Z, Feng D, Fang B, Mullican SE, You SH, Lim HW, Everett LJ, Nabel CS, Li Y, Selvakumaran V, et al. Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor. Mol Cell 2013; 52:769-82; PMID:24268577; http://dx.doi.org/10.1016/j.molcel.2013.10.022
   PubMed Web of Science ®Google Scholar
• Herzig S, Wolfrum C. Brown and white fat: from signaling to disease. Biochim Biophys Acta 2013; 1831:895; PMID:23561705; http://dx.doi.org/10.1016/j.bbalip.2013.03.009
   PubMed Web of Science ®Google Scholar
• Wu J, Cohen P, Spiegelman BM. Adaptive thermogenesis in adipocytes: is beige the new brown? Genes Dev 2013; 27:234-50; PMID:23388824; http://dx.doi.org/10.1101/gad.211649.112
   PubMed Web of Science ®Google Scholar
• van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, Drossaerts JM, Kemerink GJ, Bouvy ND, Schrauwen P, Teule GJ. Cold-activated brown adipose tissue in healthy men. N Engl J Med 2009; 360:1500-8; PMID:19357405; http://dx.doi.org/10.1056/NEJMoa0808718
   PubMed Web of Science ®Google Scholar
• Vijgen GH, Bouvy ND, Teule GJ, Brans B, Schrauwen P, van Marken Lichtenbelt WD. Brown adipose tissue in morbidly obese subjects. PLoS One 2011; 6:e17247; PMID:21390318; http://dx.doi.org/10.1371/journal.pone.0017247
   PubMed Web of Science ®Google Scholar
• Vijgen GH, Bouvy ND, Teule GJ, Brans B, Hoeks J, Schrauwen P, van Marken Lichtenbelt WD. Increase in brown adipose tissue activity after weight loss in morbidly obese subjects. J Clin Endocrinol Metab 2012; 97:E1229-33; PMID:22535970; http://dx.doi.org/10.1210/jc.2012-1289
   PubMed Web of Science ®Google Scholar
• Schulz TJ, Huang P, Huang TL, Xue R, McDougall LE, Townsend KL, Cypess AM, Mishina Y, Gussoni E, Tseng YH. Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature 2013; 495:379-83; PMID:23485971; http://dx.doi.org/10.1038/nature11943
   PubMed Web of Science ®Google Scholar
• Lee YH, Petkova AP, Mottillo EP, Granneman JG. In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding. Cell Metab 2012; 15:480-91; PMID:22482730; http://dx.doi.org/10.1016/j.cmet.2012.03.009
   PubMed Web of Science ®Google Scholar
• Ye L, Wu J, Cohen P, Kazak L, Khandekar MJ, Jedrychowski MP, Zeng X, Gygi SP, Spiegelman BM. Fat cells directly sense temperature to activate thermogenesis. Proc Natl Acad Sci U S A 2013; 110:12480-5; PMID:23818608; http://dx.doi.org/10.1073/pnas.1310261110
   PubMed Web of Science ®Google Scholar
• Chen KY, Brychta RJ, Linderman JD, Smith S, Courville A, Dieckmann W, Herscovitch P, Millo CM, Remaley A, Lee P, et al. Brown fat activation mediates cold-induced thermogenesis in adult humans in response to a mild decrease in ambient temperature. J Clin Endocrinol Metab 2013; 98:E1218-23; PMID:23780370; http://dx.doi.org/10.1210/jc.2012-4213
   PubMed Web of Science ®Google Scholar
• Foltz IN, Hu S, King C, Wu X, Yang C, Wang W, Weiszmann J, Stevens J, Chen JS, Nuanmanee N, et al. Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex. Sci Transl Med 2012; 4:ra153; PMID:23197570; http://dx.doi.org/10.1126/scitranslmed.3004690
   PubMedGoogle Scholar
• Alisi A, Panera N, Nobili V. Commentary: FGF21 holds promises for treating obesity-related insulin resistance and hepatosteatosis. Endocrinology 2014; 155:343-6; PMID:24248463; http://dx.doi.org/10.1210/en.2013-1828
   PubMedGoogle Scholar
• Gaich G, Chien JY, Fu H, Glass LC, Deeg MA, Holland WL, Kharitonenkov A, Bumol T, Schilske HK, Moller DE. The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes. Cell Metab 2013; 18:333-40; PMID:24011069; http://dx.doi.org/10.1016/j.cmet.2013.08.005
   PubMed Web of Science ®Google Scholar
• Yilmaz Y, Eren F, Yonal O, Kurt R, Aktas B, Celikel CA, Ozdogan O, Imeryuz N, Kalayci C, Avsar E. Increased serum FGF21 levels in patients with nonalcoholic fatty liver disease. Eur J Clin Invest 2010; 40:887-92; PMID:20624171; http://dx.doi.org/10.1111/j.1365-2362.2010.02338.x
   PubMed Web of Science ®Google Scholar
• Hondares E, Rosell M, Gonzalez FJ, Giralt M, Iglesias R, Villarroya F. Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat. Cell Metab 2010; 11:206-12; PMID:20197053; http://dx.doi.org/10.1016/j.cmet.2010.02.001
   PubMed Web of Science ®Google Scholar
• Lee P, Werner CD, Kebebew E, Celi FS. Functional thermogenic beige adipogenesis is inducible in human neck fat. Int J Obes 2014; 38:170-6; PMID:23736373; http://dx.doi.org/10.1038/ijo.2013.82
   PubMed Web of Science ®Google Scholar
• Fisher FM, Kleiner S, Douris N, Fox EC, Mepani RJ, Verdeguer F, Wu J, Kharitonenkov A, Flier JS, Maratos-Flier E, et al. FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis. Genes Dev 2012; 26:271-81; PMID:22302939; http://dx.doi.org/10.1101/gad.177857.111
   PubMed Web of Science ®Google Scholar
• De Sousa-Coelho AL, Relat J, Hondares E, Pérez-Martí A, Ribas F, Villarroya F, Marrero PF, Haro D. FGF21 mediates the lipid metabolism response to amino acid starvation. J Lipid Res 2013; 54:1786-97; PMID:23661803; http://dx.doi.org/10.1194/jlr.M033415
   PubMedGoogle Scholar
• Cuevas-Ramos D, Almeda-Valdes P, Aguilar-Salinas CA, Cuevas-Ramos G, Cuevas-Sosa AA, Gomez-Perez FJ. The role of fibroblast growth factor 21 (FGF21) on energy balance, glucose and lipid metabolism. Curr Diabetes Rev 2009; 5:216-20; PMID:19531026; http://dx.doi.org/10.2174/157339909789804396
   PubMedGoogle Scholar
• Murata Y, Konishi M, Itoh N. FGF21 as an Endocrine Regulator in Lipid Metabolism: From Molecular Evolution to Physiology and Pathophysiology. J Nutr Metab 2011; 2011:981315; PMID:21331285; http://dx.doi.org/10.1155/2011/981315
   PubMedGoogle Scholar
• Galmozzi A, Mitro N, Ferrari A, Gers E, Gilardi F, Godio C, Cermenati G, Gualerzi A, Donetti E, Rotili D, et al. Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue. Diabetes 2013; 62:732-42; PMID:23069623; http://dx.doi.org/10.2337/db12-0548
   PubMed Web of Science ®Google Scholar
• Lahm A, Paolini C, Pallaoro M, Nardi MC, Jones P, Neddermann P, Sambucini S, Bottomley MJ, Lo Surdo P, Carfí A, et al. Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases. Proc Natl Acad Sci U S A 2007; 104:17335-40; PMID:17956988; http://dx.doi.org/10.1073/pnas.0706487104
   PubMed Web of Science ®Google Scholar
• Zhang CL, McKinsey TA, Olson EN. The transcriptional corepressor MITR is a signal-responsive inhibitor of myogenesis. Proc Natl Acad Sci U S A 2001; 98:7354-9; PMID:11390982; http://dx.doi.org/10.1073/pnas.131198498
   PubMedGoogle Scholar
• Zhang CL, McKinsey TA, Lu JR, Olson EN. Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor. J Biol Chem 2001; 276:35-9; PMID:11022042; http://dx.doi.org/10.1074/jbc.M007364200
   PubMed Web of Science ®Google Scholar
• Sparrow DB, Miska EA, Langley E, Reynaud-Deonauth S, Kotecha S, Towers N, Spohr G, Kouzarides T, Mohun TJ. MEF-2 function is modified by a novel co-repressor, MITR. EMBO J 1999; 18:5085-98; PMID:10487760; http://dx.doi.org/10.1093/emboj/18.18.5085
   PubMed Web of Science ®Google Scholar
• Wong RH, Chang I, Hudak CS, Hyun S, Kwan HY, Sul HS. A role of DNA-PK for the metabolic gene regulation in response to insulin. Cell 2009; 136:1056-72; PMID:19303849; http://dx.doi.org/10.1016/j.cell.2008.12.040
   PubMed Web of Science ®Google Scholar
• Méjat A, Ramond F, Bassel-Duby R, Khochbin S, Olson EN, Schaeffer L. Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression. Nat Neurosci 2005; 8:313-21; PMID:15711539; http://dx.doi.org/10.1038/nn1408
   PubMed Web of Science ®Google Scholar
• Muralidhar SA, Ramakrishnan V, Kalra IS, Li W, Pace BS. Histone deacetylase 9 activates gamma-globin gene expression in primary erythroid cells. J Biol Chem 2011; 286:2343-53; PMID:21078662; http://dx.doi.org/10.1074/jbc.M110.115725
   PubMedGoogle Scholar
• Sugo N, Oshiro H, Takemura M, Kobayashi T, Kohno Y, Uesaka N, Song WJ, Yamamoto N. Nucleocytoplasmic translocation of HDAC9 regulates gene expression and dendritic growth in developing cortical neurons. Eur J Neurosci 2010; 31:1521-32; PMID:20525066
   PubMed Web of Science ®Google Scholar
• Yan K, Cao Q, Reilly CM, Young NL, Garcia BA, Mishra N. Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity. J Biol Chem 2011; 286:28833-43; PMID:21708950; http://dx.doi.org/10.1074/jbc.M111.233932
   PubMedGoogle Scholar
• Yuan Z, Peng L, Radhakrishnan R, Seto E. Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein. J Biol Chem 2010; 285:39329-38; PMID:20947501; http://dx.doi.org/10.1074/jbc.M110.179333
   PubMed Web of Science ®Google Scholar
• Archer KJ, Mas VR, Maluf DG, Fisher RA. High-throughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCV-associated hepatocellular carcinoma. Mol Genet Genomics 2010; 283:341-9; PMID:20165882; http://dx.doi.org/10.1007/s00438-010-0522-y
   PubMed Web of Science ®Google Scholar
• Lenoir O, Flosseau K, Ma FX, Blondeau B, Mai A, Bassel-Duby R, Ravassard P, Olson EN, Haumaitre C, Scharfmann R. Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9. Diabetes 2011; 60:2861-71; PMID:21953612; http://dx.doi.org/10.2337/db11-0440
   PubMed Web of Science ®Google Scholar
• Zhang CL, McKinsey TA, Olson EN. Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation. Mol Cell Biol 2002; 22:7302-12; PMID:12242305; http://dx.doi.org/10.1128/MCB.22.20.7302-7312.2002
   PubMed Web of Science ®Google Scholar
• Beier UH, Akimova T, Liu Y, Wang L, Hancock WW. Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells. Curr Opin Immunol 2011; 23:670-8; PMID:21798734; http://dx.doi.org/10.1016/j.coi.2011.07.002
   PubMedGoogle Scholar
• Markus HS, Mäkelä KM, Bevan S, Raitoharju E, Oksala N, Bis JC, O’Donnell C, Hainsworth A, Lehtimäki T. Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis. Stroke 2013; 44:1220-5; PMID:23449258; http://dx.doi.org/10.1161/STROKEAHA.111.000217
   PubMed Web of Science ®Google Scholar
• Bellenguez C, Bevan S, Gschwendtner A, Spencer CC, Burgess AI, Pirinen M, Jackson CA, Traylor M, Strange A, Su Z, et al.; International Stroke Genetics Consortium (ISGC); Wellcome Trust Case Control Consortium 2 (WTCCC2). Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet 2012; 44:328-33; PMID:22306652; http://dx.doi.org/10.1038/ng.1081
   PubMed Web of Science ®Google Scholar