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Bioengineered Bugs Volume 1, 2010 - Issue 1
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In vivo persistence and protective efficacy of the Bacille Calmette Guérin vaccine overexpressing the HspX latency antigen

Joanne M. Spratt Centenary Institute of Cancer Medicine and Cell Biology, Discipline of Infectious Diseases and Immunology, University of Sydney, Australia
,
Warwick J. Britton Centenary Institute of Cancer Medicine and Cell Biology; Discipline of Medicine and Discipline of Infectious Diseases and Immunology, University of Sydney, Australia
&
James A. Triccas Centenary Institute of Cancer Medicine and Cell Biology; Microbial Pathogenesis and Immunity Group, Discipline of Infectious Diseases and Immunology, University of Sydney, AustraliaCorrespondence[email protected]
Pages 61-65 | Received 18 Aug 2009, Accepted 09 Sep 2009, Published online: 01 Jan 2010

References

  • Dye C, Bassili A, Bierrenbach AL, Broekmans JF, Chadha VK, Glaziou P, et al. Measuring tuberculosis burden, trends and the impact of control programmes. Lancet Infect Dis 2008; 8:233 - 243
  • Hoft DF. Tuberculosis vaccine development: goals, immunological design and evaluation. Lancet 2008; 372:164 - 175
  • Vitoria M, Granich R, Gilks CF, Gunneberg C, Hosseini M, Were W, et al. The global fight against HIV/AIDS, tuberculosis and malaria: current status and future perspectives. Am J Clin Pathol 2009; 131:844 - 848
  • Karakousis PC, Yoshimatsu T, Lamichhane G, Woolwine SC, Nuermberger EL, Grosset J. Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice. J Exp Med 2004; 200:647 - 657
  • Chang Z, Primm TP, Jakana J, Lee IH, Serysheva I, Chiu W, et al. Mycobacterium tuberculosis 16-kDa antigen (Hsp16.3) functions as an oligomeric structure in vitro to suppress thermal aggregation. J Biol Chem 1996; 271:7218 - 7223
  • Yuan Y, Crane DD, Simpson RM, Zhu YQ, Hickey MJ, Sherman DR, et al. The 16-kDa alpha-crystallin (Acr) protein of Mycobacterium tuberculosis is required for growth in macrophages. Proc Natl Acad Sci USA 1998; 95:9578 - 9583
  • Sherman DR, Voskuil M, Schnappinger D, Liao R, Harrell MI, Schoolnik GK. Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding alpha-crystallin. Proc Natl Acad Sci USA 2001; 98:7534 - 7539
  • Garbe TR, Hibler NS, Deretic V. Response to reactive nitrogen intermediates in Mycobacterium tuberculosis: induction of the 16-kilodalton alpha-crystallin homolog by exposure to nitric oxide donors. Infect Immun 1999; 67:460 - 465
  • Shi L, Jung YJ, Tyagi S, Gennaro ML, North RJ. Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of nonreplicating persistence. Proc Natl Acad Sci USA 2003; 100:241 - 246
  • Demissie A, Leyten EM, Abebe M, Wassie L, Aseffa A, Abate G, et al. Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clin Vaccine Immunol 2006; 13:179 - 186
  • Geluk A, Lin MY, van Meijgaarden KE, Leyten EM, Franken KL, Ottenhoff TH, et al. T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination. Infect Immun 2007; 75:2914 - 2921
  • Lin MY, Geluk A, Smith SG, Stewart AL, Friggen AH, Franken KL, et al. Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. Infect Immun 2007; 75:3523 - 3530
  • Stover CK, de la Cruz VF, Fuerst TR, Burlein JE, Benson LA, Bennett LT, et al. New use of BCG for recombinant vaccines. Nature 1991; 351:456 - 460
  • Andersen P. Vaccine strategies against latent tuberculosis infection. Trends Microbiol 2007; 15:7 - 13
  • Yuan Y, Crane DD, Barry CE 3rd. Stationary phase-associated protein expression in Mycobacterium tuberculosis: function of the mycobacterial alpha-crystallin homolog. J Bacteriol 1996; 178:4484 - 4492
  • Via LE, Lin PL, Ray SM, Carrillo J, Allen SS, Eum SY, et al. Tuberculous granulomas are hypoxic in guinea pigs, rabbits and nonhuman primates. Infect Immun 2008; 76:2333 - 2340
  • Hu Y, Movahedzadeh F, Stoker NG, Coates AR. Deletion of the Mycobacterium tuberculosis alpha-crystallin-like hspX gene causes increased bacterial growth in vivo. Infect Immun 2006; 74:861 - 868
  • Roupie V, Romano M, Zhang L, Korf H, Lin MY, Franken KL, et al. Immunogenicity of eight dormancy regulon-encoded proteins of Mycobacterium tuberculosis in DNA-vaccinated and tuberculosis-infected mice. Infect Immun 2007; 75:941 - 949
  • Triccas J, Britton W, Gicquel B. Isolation of strong expression signals of Mycobacterium tuberculosis. Microbiology 2001; 147:1253 - 1258
  • Palendira U, Kamath AT, Feng CG, Martin E, Chaplin PJ, Triccas JA, et al. Coexpression of interleukin-12 chains by a self-splicing vector increases the protective cellular immune response of DNA and Mycobacterium bovis BCG vaccines against Mycobacterium tuberculosis. Infect Immun 2002; 70:1949 - 1956

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