1,221
Views
28
CrossRef citations to date
0
Altmetric
Research Paper

Shape in migration

 Quantitative image analysis of migrating chemoresistant HCT-8 colon cancer cells

, , , , , , , & show all
Pages 450-459 | Received 08 Aug 2013, Accepted 09 Oct 2013, Published online: 22 Oct 2013

References

  • Cunningham D, Atkin W, Lenz HJ, Lynch HT, Minsky B, Nordlinger B, Starling N. Colorectal cancer. Lancet 2010; 375:1030 - 47; http://dx.doi.org/10.1016/S0140-6736(10)60353-4; PMID: 20304247
  • Crea F, Nobili S, Paolicchi E, Perrone G, Napoli C, Landini I, Danesi R, Mini E. Epigenetics and chemoresistance in colorectal cancer: an opportunity for treatment tailoring and novel therapeutic strategies. Drug Resist Updat 2011; 14:280 - 96; http://dx.doi.org/10.1016/j.drup.2011.08.001; PMID: 21955833
  • De Angelis PM, Svendsrud DH, Kravik KL, Stokke T. Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery. Mol Cancer 2006; 5:20; http://dx.doi.org/10.1186/1476-4598-5-20; PMID: 16709241
  • Dallas NA, Xia L, Fan F, Gray MJ, Gaur P, van Buren G 2nd, Samuel S, Kim MP, Lim SJ, Ellis LM. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res 2009; 69:1951 - 7; http://dx.doi.org/10.1158/0008-5472.CAN-08-2023; PMID: 19244128
  • Cristini V, Frieboes HB, Gatenby R, Caserta S, Ferrari M, Sinek J. Morphologic instability and cancer invasion. Clin Cancer Res 2005; 11:6772 - 9; http://dx.doi.org/10.1158/1078-0432.CCR-05-0852; PMID: 16203763
  • Ferreira SC Jr., Martins ML, Vilela MJ. Morphology transitions induced by chemotherapy in carcinomas in situ. Phys Rev E Stat Nonlin Soft Matter Phys 2003; 67:051914; http://dx.doi.org/10.1103/PhysRevE.67.051914; PMID: 12786185
  • Heckman CA, Jamasbi RJ. Describing shape dynamics in transformed cells through latent factors. Exp Cell Res 1999; 246:69 - 82; http://dx.doi.org/10.1006/excr.1998.4242; PMID: 9882516
  • Bizzarri M, Pasqualato A, Cucina A, Pasta V. Physical forces and non linear dynamics mould fractal cell shape: quantitative morphological parameters and cell phenotype. Histol Histopathol 2013; 28:155 - 74; PMID: 23275300
  • Dinicola S, D’Anselmi F, Pasqualato A, Proietti S, Lisi E, Cucina A, Bizzarri M. A systems biology approach to cancer: fractals, attractors, and nonlinear dynamics. OMICS 2011; 15:93 - 104; http://dx.doi.org/10.1089/omi.2010.0091; PMID: 21319994
  • Ingber DE. How cells (might) sense microgravity. FASEB J 1999; 13:Suppl S3 - 15; PMID: 10352140
  • Heckman CA. Geometrical constraints on the shape of cultured cells. Cytometry 1990; 11:771 - 83; http://dx.doi.org/10.1002/cyto.990110703; PMID: 2272242
  • Kamran SC, Reichman DE, Missmer SA, Correia KF, Karaca N, Romano A, Racowsky C. Day 3 embryo shape as a morphologic selection parameter in in vitro fertilization. J Assist Reprod Genet 2012; 29:1135 - 9; http://dx.doi.org/10.1007/s10815-012-9842-7; PMID: 22890423
  • Ficsor L, Varga VS, Tagscherer A, Tulassay Z, Molnar B. Automated classification of inflammation in colon histological sections based on digital microscopy and advanced image analysis. Cytometry A 2008; 73:230 - 7; http://dx.doi.org/10.1002/cyto.a.20527; PMID: 18228558
  • Pasqualato A, Palombo A, Cucina A, Mariggiò MA, Galli L, Passaro D, Dinicola S, Proietti S, D’Anselmi F, Coluccia P, et al. Quantitative shape analysis of chemoresistant colon cancer cells: correlation between morphotype and phenotype. Exp Cell Res 2012; 318:835 - 46; http://dx.doi.org/10.1016/j.yexcr.2012.01.022; PMID: 22342954
  • Marshall WF. Origins of cellular geometry. BMC Biol 2011; 9:57 - 71; http://dx.doi.org/10.1186/1741-7007-9-57; PMID: 21880160
  • Yilmaz M, Christofori G. Mechanisms of motility in metastasizing cells. Mol Cancer Res 2010; 8:629 - 42; http://dx.doi.org/10.1158/1541-7786.MCR-10-0139; PMID: 20460404
  • Palmer TD, Ashby WJ, Lewis JD, Zijlstra A. Targeting tumor cell motility to prevent metastasis. Adv Drug Deliv Rev 2011; 63:568 - 81; http://dx.doi.org/10.1016/j.addr.2011.04.008; PMID: 21664937
  • Sullivan R, Holden T, Tremberger G Jr., Cheung E, Branch C, Burrero J, Surpris G, Quintana S, Rameau A, Gadura N, et al. Fractal dimension of breast cancer cell migration in a wound healing assay. Int. J. Biol. Life Sci. 2011; 7:170 - 5
  • Swaminathan V, Mythreye K, O’Brien ET, Berchuck A, Blobe GC, Superfine R. Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines. Cancer Res 2011; 71:5075 - 80; http://dx.doi.org/10.1158/0008-5472.CAN-11-0247; PMID: 21642375
  • Wirtz D, Konstantopoulos K, Searson PC. The physics of cancer: the role of physical interactions and mechanical forces in metastasis. Nat Rev Cancer 2011; 11:512 - 22; http://dx.doi.org/10.1038/nrc3080; PMID: 21701513
  • Xu W, Mezencev R, Kim B, Wang L, McDonald J, Sulchek T. Cell stiffness is a biomarker of the metastatic potential of ovarian cancer cells. PLoS One 2012; 7:e46609; http://dx.doi.org/10.1371/journal.pone.0046609; PMID: 23056368
  • Byun S, Son S, Amodei D, Cermak N, Shaw J, Kang JH, Hecht VC, Winslow MM, Jacks T, Mallick P, et al. Characterizing deformability and surface friction of cancer cells. Proc Natl Acad Sci U S A 2013; 110:7580 - 5; http://dx.doi.org/10.1073/pnas.1218806110; PMID: 23610435
  • Friedl P, Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol 2009; 10:445 - 57; http://dx.doi.org/10.1038/nrm2720; PMID: 19546857
  • Huang S, Ingber DE. Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks. Exp Cell Res 2000; 261:91 - 103; http://dx.doi.org/10.1006/excr.2000.5044; PMID: 11082279
  • Watson PA. Function follows form: generation of intracellular signals by cell deformation. FASEB J 1991; 5:2013 - 9; PMID: 1707019
  • Jaasma MJ, Jackson WM, Keaveny TM. The effects of morphology, confluency, and phenotype on whole-cell mechanical behavior. Ann Biomed Eng 2006; 34:759 - 68; http://dx.doi.org/10.1007/s10439-005-9052-x; PMID: 16604293
  • Ingber DE. Mechanical control of tissue growth: function follows form. Proc Natl Acad Sci U S A 2005; 102:11571 - 2; http://dx.doi.org/10.1073/pnas.0505939102; PMID: 16091458
  • Jahnen-Dechent W, Simon U. Function follows form: shape complementarity and nanoparticle toxicity. Nanomedicine (Lond) 2008; 3:601 - 3; http://dx.doi.org/10.2217/17435889.3.5.601; PMID: 18817462
  • Watt FM, Jordan PW, O’Neill CH. Cell shape controls terminal differentiation of human epidermal keratinocytes. Proc Natl Acad Sci U S A 1988; 85:5576 - 80; http://dx.doi.org/10.1073/pnas.85.15.5576; PMID: 2456572
  • Roskelley CD, Desprez PY, Bissell MJ. Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc Natl Acad Sci U S A 1994; 91:12378 - 82; http://dx.doi.org/10.1073/pnas.91.26.12378; PMID: 7528920
  • Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE. Geometric control of cell life and death. Science 1997; 276:1425 - 8; http://dx.doi.org/10.1126/science.276.5317.1425; PMID: 9162012
  • McBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen CS. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell 2004; 6:483 - 95; http://dx.doi.org/10.1016/S1534-5807(04)00075-9; PMID: 15068789
  • Cross SS. Fractals in pathology. J Pathol 1997; 182:1 - 8; http://dx.doi.org/10.1002/(SICI)1096-9896(199705)182:1<1::AID-PATH808>3.0.CO;2-B; PMID: 9227334
  • Cesar RM Jr.. Application and assessment of multiscale bending energy for morphometric characterization of neural cells. Rev Sci Instrum 1997; 68:2177 - 86; http://dx.doi.org/10.1063/1.1148112
  • Ferranti F, D’Anselmi F, Caruso M, Lei V, Dinicola S, Pasqualato A, Cucina A, Palombo A, Ricci G, Catizone A, et al. TCam-2 seminoma cells exposed to egg-derived microenvironment modify their shape, adhesive pattern and migratory behaviour: a molecular and morphometric analysis. PLoS One 2013; 8:e76192; http://dx.doi.org/10.1371/journal.pone.0076192; PMID: 24098438
  • Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, et al, Physical Sciences - Oncology Centers Network. A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep 2013; 3:1449; http://dx.doi.org/10.1038/srep01449; PMID: 23618955
  • Guck J, Schinkinger S, Lincoln B, Wottawah F, Ebert S, Romeyke M, Lenz D, Erickson HM, Ananthakrishnan R, Mitchell D, et al. Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence. Biophys J 2005; 88:3689 - 98; http://dx.doi.org/10.1529/biophysj.104.045476; PMID: 15722433
  • Sołtys Z, Ziaja M, Pawlínski R, Setkowicz Z, Janeczko K. Morphology of reactive microglia in the injured cerebral cortex. Fractal analysis and complementary quantitative methods. J Neurosci Res 2001; 63:90 - 7; http://dx.doi.org/10.1002/1097-4547(20010101)63:1<90::AID-JNR11>3.0.CO;2-9; PMID: 11169618
  • Suresh S, Spatz J, Mills JP, Micoulet A, Dao M, Lim CT, Beil M, Seufferlein T. Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria. Acta Biomater 2005; 1:15 - 30; http://dx.doi.org/10.1016/j.actbio.2004.09.001; PMID: 16701777

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.