Multiwalled carbon nanotubes enhance human bone marrow mesenchymal stem cells’ spreading but delay their proliferation in the direction of differentiation acceleration

References

• Khang D, Park GE, Webster TJ. Enhanced chondrocyte densities on carbon nanotube composites: the combined role of nanosurface roughness and electrical stimulation. J Biomed Mater Res A 2008; 86(1):253-60; PMID:18186050; http://dx.doi.org/10.1002/jbm.a.31803
   PubMed Web of Science ®Google Scholar
• Mattson MP, Haddon RC, Rao AM. Molecular functionalization of carbon nanotubes and use as substrates for neuronal growth. J Mol Neurosci 2000; 14(3):175-82; PMID:10984193; http://dx.doi.org/10.1385/JMN:14:3:175
   PubMed Web of Science ®Google Scholar
• Zanello LP, Zhao Bin, Hu Hui, and Haddon Robert C. Bone Cell Proliferation on Carbon Nanotubes. NanoLetters 2006; 6:562-7; PMID:16522063; http://dx.doi.org/10.1021/nl051861e
   PubMedGoogle Scholar
• Li X, Liu H, Niu X, Yu B, Fan Y, Feng Q, Cui FZ, Watari F. The use of carbon nanotubes to induce osteogenic differentiation of human adipose-derived MSCs in vitro and ectopic bone formation in vivo. Biomaterials 2012; 33:4818-27; PMID:22483242; http://dx.doi.org/10.1016/j.biomaterials.2012.03.045
   PubMed Web of Science ®Google Scholar
• Aoki N, Akasaka T, Watari F, and Yokoyama A. Carbon nanotubes as scaffolds for cell culture and effect on cellular function. Dent Mater J 2007; 26(2):178-85; PMID:17621932; http://dx.doi.org/10.4012/dmj.26.178
   PubMedGoogle Scholar
• Zhang D, Yi C, Zhang J, Chen Y, Yao X, and Yang M. Effects of carbon nanotubes on the proliferation and differentiation of primary osteoblasts. Nanotechnology 2007; 18:475102-10; http://dx.doi.org/10.1088/0957-4484/18/47/475102
   Web of Science ®Google Scholar
• Tutak W, Park KH, Vasilov A, Starovoytov V, Fanchini G, Cai SQ, Partridge NC, Sesti F, Chhowalla M. Toxicity induced enhanced extracellular matrix production in osteoblastic cells cultured on single-walled carbon nanotube networks. Nanotechnology 2009; 20:255101; PMID:19487801; http://dx.doi.org/10.1088/0957-4484/20/25/255101
   PubMedGoogle Scholar
• George JH, Shaffer MS, and Stevens MM. Investigating the cellular response to nanofibrous materials by use of a multi-walled carbon nanotube model. J Exp Nanosci 2006; 1(1):1-12; http://dx.doi.org/10.1080/17458080500463149
   Web of Science ®Google Scholar
• Ishikawa K, Akasaka T, Yawaka Y, Watari F. High functional expression of osteoblasts on imogolite, aluminosilicate nanotubes. J Biomed Nanotechnology 2010; 6:59-65; PMID: 20499833; http://dx.doi.org/10.1166/jbn.2010.1092
   PubMedGoogle Scholar
• 10. Akasaka T, Yokoyama A, Matsuoka M, et al. Adhesion of human osteoblast-like cells (Saos-2) to carbon nanotube sheets. Biomed Mater Eng 2009; 19:147-53; PMID:19581708; http://dx.doi.org/10.3233/BME-2009-0574
   PubMedGoogle Scholar
• Kilpadi KL, Sawyer AA, Prince CW, Chang PL, and Bellis SL. Primary human marrow stromal cells and SaOs-2 osteosarcoma cells use different mechanisms to adhere to hydroxylapatite. J Biomed Mater Res A 2004; 68A:273-85 PMID:14704969
   PubMedGoogle Scholar
• Kroustalli AA, Kourkouli SN, Deligianni DD. Cellular function and adhesion mechanisms of human bone marrow mesenchymal stem cells on multi-walled carbon nanotubes. Ann Biomed Eng 2013; 41(12):2655-65; PMID:23820769; http://dx.doi.org/10.1007/s10439-013-0860-0
   PubMedGoogle Scholar
• Klein MO, Bijelic A, Ziebart T, Koch F, Kämmerer PW, Wieland M, Konerding MA, Al-Nawas B. Scale-Structured Hydrophilic Titanium Surfaces Promote Early Osteogenic Gene Response for Cell Adhesion and Cell Differentiation. Clin Implant Dent Rel Res 2011; 15(2):166-75; PMID: 21682843; http://dx.doi.org/10.1111/j.1708-8208.2011.00339.x
   PubMedGoogle Scholar
• Boyan BD, Lossdörfer S, Wang L, Zhao G, Lohmann CH, Cochran DL and Schwartz Z. Osteoblasts generate an osteogenic microenvironment when grown on surfaces with rough microtopographies. European cells and Materials 2003; 6:22-7; PMID:14577052
   PubMedGoogle Scholar
• Khang D, Choi J, Im Y-M, Kim Y-J, Jang J-H, Kang S S, Nam T-H, Song J and Park J-W. Role of subnano-, nano- and submicron-surface features on osteoblast differentiation of bone marrow mesenchymal stem cells. Biomaterials 2012; 33:5997-6007; PMID:22632766; http://dx.doi.org/10.1016/j.biomaterials.2012.05.005
   PubMed Web of Science ®Google Scholar
• Gittens RA, Olivares-Navarrete R, McLachlan T, Cai Y, Hyzy SL, Schneider JM, Schwartz Z, Sandhage KH, Boyan BD. Differential responses of osteoblast lineage cells to nanotopographically-modified, microroughened titanium-aluminum-vanadium alloy surfaces. Biomaterials 2012; 33:8986-94; PMID:22989383; http://dx.doi.org/10.1016/j.biomaterials.2012.08.059
   PubMed Web of Science ®Google Scholar
• Schofer MD, Veltum A, Theisen C, Chen F, Agarwal S, Fuchs-Winkelmann S, Paletta JRJ. Functionalisation of PLLA nanofiber scaffolds using a possible cooperative effect between collagen type I and BMP-2: impact on growth and osteogenic differentiation of human mesenchymal stem cells. J Mater Sci Mater Med 2011; 22:1753-62; PMID:21604139; http://dx.doi.org/10.1007/s10856-011-4341-4
   PubMedGoogle Scholar
• Chang J-C, Fujita S, Tonami H, Kato K, Iwata H and Hsu S. Cell orientation and regulation of cell–cell communication in human mesenchymal stem cells on different patterns of electrospun fibers. Biomed Mater 2013; 8:055002; PMID:24002690; http://dx.doi.org/10.1088/1748-6041/8/5/055002
   PubMedGoogle Scholar
• Oh S, Brammer KS, Julie Li YS, Teng D, Engler AJ, Chien S, and Jin S. Stem cell fate dictated solely by altered nanotube dimension. PNAS 2009; 106: 2130-35; PMID:19179282; http://dx.doi.org/10.1073/pnas.0813200106
   PubMed Web of Science ®Google Scholar
• Knabe C, Stiller M, Berger G, Reif D, Gildenhaar R, Howlett CR, Zreiqat H. The effect of bioactive glass ceramics on the expression of bone-related genes and proteins in vitro. Clin Oral Impl Res 2005; 16:119-27; PMID:15642039; http://dx.doi.org/10.1111/j.1600-0501.2004.01066.x
   PubMed Web of Science ®Google Scholar
• Lian JB and Stein GS. Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation. Iowa Orthop J 1995; 15:118-40; PMID:7634023
   PubMedGoogle Scholar
• McBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen CS. Cell shape, cytoskeletal tension, and rhoA regulate stem cell lineage commitment. Dev Cell 2004; 6:483-95; PMID:15068789; http://dx.doi.org/10.1016/S1534-5807(04)00075-9
   PubMed Web of Science ®Google Scholar
• Linez-Bataillon P, Monchau F, Bigerelle M, Hildebrand HF. In vitro MC3T3 osteoblast adhesion with respect to surface roughness of Ti6Al4V substrates. Biomol Eng 2002; 19:133-41; PMID:12202174; http://dx.doi.org/10.1016/S1389-0344(02)00024-2
   PubMedGoogle Scholar
• Brunette DM. The effects of implant surface topography on the behavior of cells. Int J Oral Maxillofac Implants 1988; 3:231-46; PMID:3075965
   PubMedGoogle Scholar
• Zhao G, Raines AL, Wieland M, Schwartz Z, and Boyan BD. Requirement for Both Micron and Submicron Scale Structure for Synergistic Responses of Osteoblasts to Substrate Surface Energy and Topography. Biomaterials 2007; 28: 2821-29; PMID:17368532; http://dx.doi.org/10.1016/j.biomaterials.2007.02.024
   PubMed Web of Science ®Google Scholar
• Born AK, Rottmar M, Lischer S, Pleskova M, Bruinink A, and Maniura-Weber K. Correlating cell architecture with osteogenesis: first steps towards live single cell monitoring. European Cells and Materials 2009; 18:49-62; PMID:19856264
   PubMedGoogle Scholar
• Yourek G, Hussain MA, Mao JJ. Cytoskeletal changes of mesenchymal stem cells during differentiation. ASAIO J 2007; 53:219-28; PMID:17413564; http://dx.doi.org/10.1097/MAT.0b013e31802deb2d
   PubMed Web of Science ®Google Scholar
• Boettiger D. Mechanical control of integrin-mediated adhesion and signaling. Current Opinion in Cell Biology 2012; 24:592-599; PMID:22857903; http://dx.doi.org/10.1016/j.ceb.2012.07.002
   PubMed Web of Science ®Google Scholar
• Teo BK, Wong ST, Lim CK, Kung TY, Yap CH, Ramagopal Y, Romer LH, Yim EK. Nanotopography modulates mechanotransduction of stem cells and induces differentiation through focal adhesion kinase. ACS Nano 2013; 7:4785-98; PMID:23672596; http://dx.doi.org/10.1021/nn304966z
   PubMed Web of Science ®Google Scholar
• Berrier AL, Yamada KM. Cell-matrix adhesion. J Cell Physiol 2007; 213:565-73; PMID:17680633; http://dx.doi.org/10.1002/jcp.21237
   PubMed Web of Science ®Google Scholar
• Huttenlocher A, Sandborg RR and Horwitz AF. Adhesion in cell migration, Current Opinion in Cell Biology 1995; 7:697-706; PMID:8573345; http://dx.doi.org/10.1016/0955-0674(95)80112-X
   PubMed Web of Science ®Google Scholar
• Hwang NS, Varghese S and Elisseeff J. Controlled differentiation of stem cells. Adv Drug Deliv Rev 2008; 60:199-214; PMID:18006108; http://dx.doi.org/10.1016/j.addr.2007.08.036
   PubMed Web of Science ®Google Scholar
• Reddy AR, Reddy YN, Krishna DR, Himabindu V. Multi wall carbon nanotubes induce oxidative stress and cytotoxicity in human embryonic kidney (HEK293) cells. Toxicology 2010; 272:11-6; PMID:20371264; http://dx.doi.org/10.1016/j.tox.2010.03.017
   PubMed Web of Science ®Google Scholar
• Firme CP 3rd, Bandaru PR. Toxicity issues in the application of carbon nanotubes to biological systems. Nanomedicine 2010; 6:245-256; PMID:19699321; http://dx.doi.org/10.1016/j.nano.2009.07.003
   PubMed Web of Science ®Google Scholar
• Tsukahara T, Haniu H. Cellular cytotoxic response induced by highly purified multi-wall carbon nanotube in human lung cells. Mol Cell Biochem 2011; 352:57-63; PMID:21298324; http://dx.doi.org/10.1007/s11010-011-0739-z
   PubMed Web of Science ®Google Scholar