1,836
Views
30
CrossRef citations to date
0
Altmetric
Review

Ring finger protein 146/Iduna is a Poly(ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase

, , &
Pages 463-471 | Received 12 Aug 2011, Accepted 10 Oct 2011, Published online: 01 Nov 2011

References

  • Fang S, Lorick KL, Jensen JP, Weissman AM. RING finger ubiquitin protein ligases: implications for tumorigenesis, metastasis and for molecular targets in cancer. Semin Cancer Biol 2003; 13:5 - 14; PMID: 12507552; http://dx.doi.org/10.1016/S1044-579X(02)00095-0
  • Ardley HC. Ring finger ubiquitin protein ligases and their implication to the pathogenesis of human diseases. Curr Pharm Des 2009; 15:3697 - 3715; PMID: 19925421; http://dx.doi.org/10.2174/138161209789271807
  • Zhang Y, Liu S, Mickanin C, Feng Y, Charlat O, Michaud GA, et al. RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling. Nat Cell Biol 2011; 13:623 - 629; PMID: 21478859; http://dx.doi.org/10.1038/ncb2222
  • Andrabi SA, Kang HC, Haince JF, Lee YI, Zhang J, Chi Z, et al. Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death. Nat Med 2011; 17:692 - 699; PMID: 21602803; http://dx.doi.org/10.1038/nm.2387
  • Kang HC, Lee YI, Shin JH, Andrabi SA, Chi Z, Gagné JP, et al. Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage. Proc Natl Acad Sci USA 2011; 108:14103 - 14108; PMID: 21825151; http://dx.doi.org/10.1073/pnas.1108799108
  • David KK, Andrabi SA, Dawson TM, Dawson VL. Parthanatos, a messenger of death. Front Biosci 2009; 14:1116 - 1128; PMID: 19273119; http://dx.doi.org/10.2741/3297
  • Wang LB, Zhang LY, Shan CH. A new form of cell death: Parthanatos. Yi Chuan 2010; 32:881 - 885; PMID: 20870608
  • Yung TM, Sato S, Satoh MS. Poly(ADP-ribosyl)ation as a DNA damage-induced post-translational modification regulating poly(ADP-ribose) polymerase-1-topoisomerase I interaction. J Biol Chem 2004; 279:39686 - 39696; PMID: 15247263; http://dx.doi.org/10.1074/jbc.M402729200
  • Andrabi SA, Dawson TM, Dawson VL. Mitochondrial and nuclear cross talk in cell death: parthanatos. Ann NY Acad Sci 2008; 1147:233 - 241; PMID: 19076445; http://dx.doi.org/10.1196/annals.1427.014
  • Wang Y, Kim NS, Haince JF, Kang HC, David KK, Andrabi SA, et al. Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). Sci Signal 2011; 4:20; PMID: 21467298; http://dx.doi.org/10.1126/scisignal.2000902
  • He X, Semenov M, Tamai K, Zeng X. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 2004; 131:1663 - 1677; PMID: 15084453; http://dx.doi.org/10.1242/dev.01117
  • Pecina-Slaus N. Wnt signal transduction pathway and apoptosis: a review. Cancer Cell Int 2010; 10:22; PMID: 20591184; http://dx.doi.org/10.1186/1475-2867-10-22
  • Latres E, Chiaur DS, Pagano M. The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. Oncogene 1999; 18:849 - 854; PMID: 10023660; http://dx.doi.org/10.1038/sj.onc.1202653
  • Lee E, Salic A, Kruger R, Heinrich R, Kirschner MW. The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol 2003; 1:10; PMID: 14551908; http://dx.doi.org/10.1371/journal.pbio.0000010
  • Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 2009; 461:614 - 620; PMID: 19759537; http://dx.doi.org/10.1038/nature08356
  • Fearon ER. PARsing the phrase “all in for Axin”-Wnt pathway targets in cancer. Cancer Cell 2009; 16:366 - 368; PMID: 19878868; http://dx.doi.org/10.1016/j.ccr.2009.10.007
  • Callow MG, Tran H, Phu L, Lau T, Lee J, Sandoval WN, et al. Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling. PLoS ONE 2011; 6:22595; PMID: 21799911; http://dx.doi.org/10.1371/journal.pone.0022595
  • Short B, Preisinger C, Körner R, Kopajtich R, Byron O, Barr FA. GRASP55-rab2 effector complex linking Golgi structure to membrane traffic. J Cell Biol 2001; 155:877 - 884; PMID: 11739401; http://dx.doi.org/10.1083/jcb.200108079
  • Duprez E, Tong JH, Dérré J, Shen SJ, Berger R, Chen Z, et al. JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4 promyelocytic leukaemia. Oncogene 1997; 14:1563 - 1570; PMID: 9129147; http://dx.doi.org/10.1038/sj.onc.1200995
  • Baguet A, Degot S, Cougot N, Bertrand E, Chenard MP, Wendling C, et al. The exon-junction-complexcomponent metastatic lymph node 51 functions in stress-granule assembly. J Cell Sci 2007; 120:2774 - 2784; PMID: 17652158; http://dx.doi.org/10.1242/jcs.009225
  • Noble CG, Song H. MLN51 stimulates the RNAhelicase activity of eIF4AIII. PLoS ONE 2007; 2:303; PMID: 17375189; http://dx.doi.org/10.1371/journal.pone.0000303
  • Degot S, Régnier CH, Wendling C, Chenard MP, Rio MC, Tomasetto C. Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer. Oncogene 2002; 21:4422 - 4434; PMID: 12080473; http://dx.doi.org/10.1038/sj.onc.1205611
  • Jackson PK, Eldridge AG. The SCF ubiquitin ligase: an extended look. Mol Cell 2002; 9:923 - 925; PMID: 12049727; http://dx.doi.org/10.1016/S1097-2765(02)00538-5
  • Cope GA, Deshaies RJ. COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 2003; 114:663 - 671; PMID: 14505567; http://dx.doi.org/10.1016/S0092-8674(03)00722-0
  • Bouchard VJ, Rouleau M, Poirier GG. PARP-1, a determinant of cell survival in response to DNA damage. Exp Hematol 2003; 31:446 - 454; PMID: 12829019; http://dx.doi.org/10.1016/S0301-472X(03)00083-3
  • Huber A, Bai P, de Murcia JM, de Murcia G. PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development. DNA Repair (Amst) 2004; 3:1103 - 1108; PMID: 15279798; http://dx.doi.org/10.1016/j.dnarep.2004.06.002
  • Vidakovic M, Poznanovic G, Bode J. DNA break repair: refined rules of an already complicated game. Biochem Cell Biol 2005; 83:365 - 373; PMID: 15959562; http://dx.doi.org/10.1139/o05-044
  • Mortusewicz O, Fouquerel E, Ame JC, Leonhardt H, Schreiber V. PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms. Nucleic Acids Res 2011; 39:5045 - 5056; PMID: 21398629; http://dx.doi.org/10.1093/nar/gkr099
  • Fisher AEO, Hochegger H, Takeda S, Caldecott KW. Poly(ADP-ribose) polymerase 1 accelerates sin-gle-strand break repair in concert with poly(ADP-ribose) glycohydrolase. Mol Cell Biol 2007; 27:5597 - 5605; PMID: 17548475; http://dx.doi.org/10.1128/MCB.02248-06
  • Erdélyi K, Bai P, Kovács I, Szabó E, Mocsár G, Kakuk A, et al. Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells. FASEB J 2009; 23:3553 - 3563; PMID: 19571039; http://dx.doi.org/10.1096/fj.09-133264
  • Lan L, Nakajima S, Oohata Y, Takao M, Okano S, Masutani M, et al. In situ analysis of repair processes for oxidative DNA damage in mammalian cells. Proc Natl Acad Sci USA 2004; 101:13738 - 13743; PMID: 15365186; http://dx.doi.org/10.1073/pnas.0406048101
  • Gold B, Kirchhof T, Stefanov S, Lautenberger J, Viale A, Garber J, et al. Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Proc Natl Acad Sci USA 2008; 105:4340 - 4345; PMID: 18326623; http://dx.doi.org/10.1073/pnas.0800441105
  • Menachem TD, Laitman Y, Kaufman B, Friedman E. The RNF146 and ECHDC1 genes as candidates for inherited breast and ovarian cancer in Jewish Ashkenazi women. Fam Cancer 2009; 8:399 - 402; PMID: 19517271; http://dx.doi.org/10.1007/s10689-009-9255-7
  • Campa D, Kaaks R, Le Marchand L, Haiman CA, Travis RC, Berg CD, et al. Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium. J Natl Cancer Inst 2011; 103:1252 - 1263; PMID: 21791674; http://dx.doi.org/10.1093/jnci/djr265
  • Nusse R, van Ooyen A, Cox D, Fung YK, Varmus H. Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature 1984; 307:131 - 136; PMID: 6318122; http://dx.doi.org/10.1038/307131a0
  • Tsukamoto AS, Grosschedl R, Guzman RC, Parslow T, Varmus HE. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell 1988; 55:619 - 625; PMID: 3180222; http://dx.doi.org/10.1016/0092-8674(88)90220-6
  • Mohinta S, Wu H, Chaurasia P, Watabe K. Wnt pathway and breast cancer. Front Biosci 2007; 12:4020 - 4033; PMID: 17485355; http://dx.doi.org/10.2741/2368
  • Veeck J, Bektas N, Hartmann A, Kristiansen G, Heindrichs U, Knüchel R, et al. Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours. Breast Cancer Res 2008; 10:82; PMID: 18826564; http://dx.doi.org/10.1186/bcr2151
  • Deng CX. BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution. Nucleic Acids Res 2006; 34:1416 - 1426; PMID: 16522651; http://dx.doi.org/10.1093/nar/gkl010
  • Deng CX. Tumorigenesis as a consequence of genetic instability in Brca1 mutant mice. Mutat Res 2001; 477:183 - 189; PMID: 11376699; http://dx.doi.org/10.1016/S0027-5107(01)00119-1
  • De Soto JA, Deng CX. PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2associated breast cancers?. Int J Med Sci 2006; 3:117 - 123; PMID: 16906222
  • von Rotz RC, Kins S, Hipfel R, von der Kammer H, Nitsch RM. The novel cytosolic RING finger protein dactylidin is upregulated in brains of patients with Alzheimer's disease. Eur J Neurosci 2005; 21:1289 - 1298; PMID: 15813938; http://dx.doi.org/10.1111/j.1460-9568.2005.03977.x
  • Gagné JP, Isabelle M, Lo KS, Bourassa S, Hendzel MJ, Dawson VL, et al. Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Res 2008; 36:6959 - 6976; PMID: 18981049; http://dx.doi.org/10.1093/nar/gkn771
  • Chen G, Li G. Increased Cul1 expression promotes melanoma cell proliferation through regulating p27 expression. Int J Oncol 2010; 37:1339 - 1344; PMID: 20878082
  • Chen G, Cheng Y, Martinka M, Li G. Cul1 expression is increased in early stages of human melanoma. Pigment Cell Melanoma Res 2010; 23:572 - 574; PMID: 20518860; http://dx.doi.org/10.1111/j.1755-148X.2010.00725.x
  • Bai J, Zhou Y, Chen G, Zeng J, Ding J, Tan Y, et al. Overexpression of Cullin1 is associated with poor prognosis of patients with gastric cancer. Hum Pathol 2011; 42:375 - 383; PMID: 21190721; http://dx.doi.org/10.1016/j.humpath.2010.09.003
  • Parsons JL, Tait PS, Finch D, Dianova II, Edelmann MJ, Khoronenkova SV, et al. Ubiquitin ligase ARFBP1/Mule modulates base excision repair. EMBO J 2009; 28:3207 - 3215; PMID: 19713937; http://dx.doi.org/10.1038/emboj.2009.243
  • Takeyama K, Aguiar RC, Gu L, He C, Freeman GJ, Kutok JL, et al. The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity. J Biol Chem 2003; 278:21930 - 21937; PMID: 12670957; http://dx.doi.org/10.1074/jbc.M301157200

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.