Rosiglitazone delayed weight loss and anorexia while attenuating adipose depletion in mice with cancer cachexia

References

• Muscaritoli M, Anker SD, Argilés J, Aversa Z, Bauer JM, Biolo G, et al. Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) “cachexia-anorexia in chronic wasting diseases” and “nutrition in geriatrics”. Clin Nutr 2010; 29:154 - 9; http://dx.doi.org/10.1016/j.clnu.2009.12.004; PMID: 20060626
   PubMed Web of Science ®Google Scholar
• Argilés JM, Almendro V, Busquets S, Lopez-Soriano FJ. The pharmacological treatment of cachexia. Curr Drug Targets 2004; 5:265 - 77; http://dx.doi.org/10.2174/1389450043490505; PMID: 15058312
   PubMed Web of Science ®Google Scholar
• Dewys WD, Begg C, Lavin PT, Band PR, Bennett JM, Bertino JR, et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am J Med 1980; 69:491 - 7; http://dx.doi.org/10.1016/S0149-2918(05)80001-3; PMID: 7424938
   PubMed Web of Science ®Google Scholar
• Warren S. The immediate causes of death in cancer. Am J Med Sci 1932; 184:610 - 5; http://dx.doi.org/10.1097/00000441-193211000-00002
   Google Scholar
• Inagaki J, Rodriguez V, Bodey GP. Causes of death in cancer patients. Cancer 1974; 33:568 - 73; http://dx.doi.org/10.1002/1097-0142(197402)33:2<568::AID-CNCR2820330236>3.0.CO;2-2; PMID: 4591273
   PubMed Web of Science ®Google Scholar
• Argilés JM. López-Soriano, Busquets S. Novel approaches to the treatment of cachexia. Drug Discov Today 2008; 13:73 - 8; http://dx.doi.org/10.1016/j.drudis.2007.10.008; PMID: 18190867
   PubMed Web of Science ®Google Scholar
• Bozzetti F, Ammatuna M, Migliavacca S, Bonalumi MG, Facchetti G, Pupa A, et al. Total parenteral nutrition prevents further nutritional deterioration in patients with cancer cachexia. Ann Surg 1987; 205:138 - 43; http://dx.doi.org/10.1097/00000658-198702000-00007; PMID: 3101624
   PubMed Web of Science ®Google Scholar
• Rohdenburg GL, Bernhard A, Krehbiel O. Sugar tolerance in cancer. J Am Med Assoc 1919; 72:528 - 30
   Google Scholar
• Moley JF, Morrison SD, Norton JA. Preoperative insulin reverses cachexia and decreases mortality in tumor-bearing rats. J Surg Res 1987; 43:21 - 8; http://dx.doi.org/10.1016/0022-4804(87)90042-4; PMID: 3599982
   PubMed Web of Science ®Google Scholar
• Moley JF, Morrison SD, Gorschboth CM, Norton JA. Body composition changes in rats with experimental cancer cachexia: improvement with exogenous insulin. Cancer Res 1988; 48:2784 - 7; PMID: 3282649
   PubMed Web of Science ®Google Scholar
• Peacock JL, Norton JA. Impact of insulin on survival of cachectic tumor bearing rats. JPEN J Parenter Enteral Nutr 1988; 12:260 - 4; http://dx.doi.org/10.1177/0148607188012003260; PMID: 3392822
   PubMed Web of Science ®Google Scholar
• Beck SA, Tisdale MJ. Effect of insulin on weight loss and tumour growth in a cachexia model. Br J Cancer 1989; 59:677 - 81; http://dx.doi.org/10.1038/bjc.1989.140; PMID: 2736199
   PubMed Web of Science ®Google Scholar
• Pearlstone DB, Wolf RF, Berman RS, Burt M, Brennan MF. Effect of systemic insulin on protein kinetics in postoperative cancer patients. Ann Surg Oncol 1994; 1:321 - 32; http://dx.doi.org/10.1007/BF02303571; PMID: 7850531
   PubMed Web of Science ®Google Scholar
• Lundholm K, Körner U, Gunnebo L, Sixt-Ammilon P, Fouladiun M, Daneryd P, et al. Insulin treatment in cancer cachexia: effects on survival, metabolism and physical functioning. Clin Cancer Res 2007; 13:2699 - 706; http://dx.doi.org/10.1158/1078-0432.CCR-06-2720; PMID: 17473202
   PubMed Web of Science ®Google Scholar
• Cersosimo E, Pisters PW, Pesola G, Rogatko A, Vydelingum NA, Bajorunas D, et al. The effect of graded doses of insulin on peripheral glucose uptake and lactate release in cancer cachexia. Surgery 1991; 109:459 - 67; PMID: 2008651
   PubMed Web of Science ®Google Scholar
• Dodesini AR, Benedini S, Terruzzi I, Sereni LP, Luzi L. Protein, glucose and lipid metabolism in the cancer cachexia: A preliminary report. Acta Oncol 2007; 46:118 - 20; http://dx.doi.org/10.1080/02841860600791491; PMID: 17438714
   PubMed Web of Science ®Google Scholar
• Asp ML, Tian M, Wendel AA, Belury MA. Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice. Int J Cancer 2010; 126:756 - 63; http://dx.doi.org/10.1002/ijc.24784; PMID: 19634137
   PubMed Web of Science ®Google Scholar
• Schenk S, Saberi M, Olefsky JM. Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest 2008; 118:2992 - 3002; http://dx.doi.org/10.1172/JCI34260; PMID: 18769626
   PubMed Web of Science ®Google Scholar
• Hauner H. The mode of action of thiazolidinediones. Diabetes Metab Res Rev 2002; 18:S10 - 5; http://dx.doi.org/10.1002/dmrr.249; PMID: 11921433
   PubMed Web of Science ®Google Scholar
• Tisdale MJ. Mechanisms of cancer cachexia. Physiol Rev 2009; 89:381 - 410; http://dx.doi.org/10.1152/physrev.00016.2008; PMID: 19342610
   PubMed Web of Science ®Google Scholar
• Wang X, Hu Z, Hu J, Du J, Mitch WE. Insulin resistance accelerates muscle protein degradation: activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology 2006; 147:4160 - 8; http://dx.doi.org/10.1210/en.2006-0251; PMID: 16777975
   PubMed Web of Science ®Google Scholar
• Evans WJ, Morley JE, Argilés J, Bales C, Baracos V, Guttridge D, et al. Cachexia: a new definition. Clin Nutr 2008; 27:793 - 9; http://dx.doi.org/10.1016/j.clnu.2008.06.013; PMID: 18718696
   PubMed Web of Science ®Google Scholar
• Gomes MD, Lecker SH, Jagoe RT, Navon A, Goldberg AL. Atrogin-1, a muscle specific F-box protein highly expressed during muscle atrophy. Proc Natl Acad Sci USA 2001; 98:14440 - 5; http://dx.doi.org/10.1073/pnas.251541198; PMID: 11717410
   PubMed Web of Science ®Google Scholar
• Bodine SC, Latres E, Baumhueter S, Lai VKM, Nunez L, Clarke BA, et al. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 2001; 294:1704 - 8; http://dx.doi.org/10.1126/science.1065874; PMID: 11679633
   PubMed Web of Science ®Google Scholar
• Mammucari C, Milan G, Romanello V, Masiero E, Rudolf R, Del Piccolo P, et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 2007; 6:458 - 71; http://dx.doi.org/10.1016/j.cmet.2007.11.001; PMID: 18054315
   PubMed Web of Science ®Google Scholar
• Strassmann G, Fong M, Kenney JS, Jacob CO. Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J Clin Invest 1992; 89:1681 - 4; http://dx.doi.org/10.1172/JCI115767; PMID: 1569207
   PubMed Web of Science ®Google Scholar
• de Lange P, Moreno M, Silvestri E, Lombardi A, Goglia F, Lanni A. Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms. FASEB J 2007; 21:3431 - 41; http://dx.doi.org/10.1096/fj.07-8527rev; PMID: 17595346
   PubMed Web of Science ®Google Scholar
• Pecqueur C, Bui T, Gelly C, Hauchard J, Barbot C, Bouillaud F, et al. Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization. FASEB J 2008; 22:9 - 18; http://dx.doi.org/10.1096/fj.07-8945com; PMID: 17855623
   PubMed Web of Science ®Google Scholar
• Tian M, Kliewer KL, Asp ML, Sout MB, Belury MA. c9t11-Conjugated linoleic acid-rich oil fails to attenuate wasting in colon-26 tumor-induced late-stage cancer cachexia in male CD2F1 mice. Mol Nutr Food Res 2011; 55:268 - 77; http://dx.doi.org/10.1002/mnfr.201000176; PMID: 20827675
   PubMed Web of Science ®Google Scholar
• Lehrke M, Lazar MA. The many faces of PPARgamma. Cell 2005; 123:993 - 9; http://dx.doi.org/10.1016/j.cell.2005.11.026; PMID: 16360030
   PubMed Web of Science ®Google Scholar
• Guerre-Millo M. Adiponectin: an update. Diabetes Metab 2008; 34:12 - 8; PMID: 18069030
   PubMed Web of Science ®Google Scholar
• Acharyya S, Ladner KJ, Nelsen LL, Damrauer J, Reiser PJ, Swoap S, et al. Cancer cachexia is regulated by selective targeting of skeletal muscle gene products. J Clin Invest 2004; 114:370 - 8; PMID: 15286803
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real time quantitative PCR and the 2(-Delta Delta C(T)). Methods 2001; 25:402 - 8; http://dx.doi.org/10.1006/meth.2001.1262; PMID: 11846609
   PubMed Web of Science ®Google Scholar