A single nucleotide polymorphism of the cholecystokinin-B receptor predicts risk for pancreatic cancer

References

• Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, et al. Cancer statistics, 2008. CA Cancer J Clin 2008; 58:71 - 96; PMID: 18287387; http://dx.doi.org/10.3322/CA.2007.0010
   PubMed Web of Science ®Google Scholar
• Rocha Lima CM, Centeno B. Update on pancreatic cancer. Curr Opin Oncol 2002; 14:424 - 430; PMID: 12130928; http://dx.doi.org/10.1097/00001622200207000-00010
   PubMed Web of Science ®Google Scholar
• Goldstein D, Carroll S, Apte M, Keogh G. Modern management of pancreatic carcinoma. Intern Med J 2004; 34:475 - 481; PMID: 15317546; http://dx.doi.org/10.1111/j.1444-0903.2004.00658.x
   PubMed Web of Science ®Google Scholar
• Wolff RA. Novel therapies for pancreatic cancer. Cancer J 2001; 7:349 - 258; PMID: 11561610
   PubMed Web of Science ®Google Scholar
• Montgomery RC, Hoffman JP, Riley LB, Rogatko A, Ridge JA, Eisenberg BL. Prediction of recurrence and survival by post-resection CA 19-9 values in patients with adenocarcinoma of the pancreas. Ann Surg Oncol 1997; 4:551 - 556; PMID: 9367020; http://dx.doi.org/10.1007/BF02305535
   PubMed Web of Science ®Google Scholar
• Louhimo J, Alfthan H, Stenman UH, Haglund C. Serum HCG beta and CA 72–4 are stronger prognostic factors than CEA, CA 19-9 and CA 242 in pancreatic cancer. Oncology 2004; 66:126 - 131; PMID: 15138364; http://dx.doi.org/10.1159/000077438
   PubMed Web of Science ®Google Scholar
• Koopmann J, Buckhaults P, Brown DA, Zahurak ML, Sato N, Fukushima N, et al. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers. Clin Cancer Res 2004; 10:2386 - 2392; PMID: 15073115; http://dx.doi.org/10.1158/1078-0432.CCR-03-0165
   PubMed Web of Science ®Google Scholar
• Koopmann J, Fedarko NS, Jain A, Maitra A, Iacobuzio-Donahue C, Rahman A, et al. Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma. Cancer Epidemiol Biomarkers Prev 2004; 13:487 - 491; PMID: 15006928
   PubMed Web of Science ®Google Scholar
• Garcea G, Neal CP, Pattenden CJ, Steward WP, Berry DP. Molecular prognostic markers in pancreatic cancer: a systematic review. Eur J Cancer 2005; 41:2213 - 2236; PMID: 16146690; http://dx.doi.org/10.1016/j.ejca.2005.04.044
   PubMed Web of Science ®Google Scholar
• Goggins M. Molecular markers of early pancreatic cancer. J Clin Oncol 2005; 23:4524 - 4531; PMID: 16002843; http://dx.doi.org/10.1200/JCO.2005.19.
   PubMed Web of Science ®Google Scholar
• Goggins M, Canto M, Hruban R. Can we screen high-risk individuals to detect early pancreatic carcinoma?. J Surg Oncol 2000; 74:243 - 248; PMID: 10962454; http://dx.doi.org/10.1002/1096-9098(200008)74:4<243::AIDJSO1>3.0.CO;2-C
   PubMed Web of Science ®Google Scholar
• Tada M, Omata M, Kawai S, Saisho H, Ohto M, Saiki RK, et al. Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma. Cancer Res 1993; 53:2472 - 2474; PMID: 8495407
   PubMed Web of Science ®Google Scholar
• Korc M. Driver Mutations. Cancer Biol Ther 2010; 10:588 - 591; PMID: 20716952; http://dx.doi.org/10.4161/cbt.10.6.13128
   PubMed Web of Science ®Google Scholar
• Pisegna JR, de Weerth A, Huppi K, Wank SA. Molecular cloning of the human brain and gastric cholecystokinin receptor: structure, functional expression and chromosomal localization. Biochem Biophys Res Commun 1992; 189:296 - 303; PMID: 1280419; http://dx.doi.org/10.1016/0006-291X(92)91557-7
   PubMed Web of Science ®Google Scholar
• Wank SA, Harkins R, Jensen RT, Shapira H, de Weerth A, Slattery T. Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas. Proc Natl Acad Sci USA 1992; 89:3125 - 3129; PMID: 1313582; http://dx.doi.org/10.1073/pnas.89.7.3125
   PubMed Web of Science ®Google Scholar
• Wank SA, Pisegna JR, de Weerth A. Brain and gastrointestinal cholecystokinin receptor family: structure and functional expression. Proc Natl Acad Sci USA 1992; 89:8691 - 8695; PMID: 1528881; http://dx.doi.org/10.1073/pnas.89.18.8691
   PubMed Web of Science ®Google Scholar
• Wank SA. G protein-coupled receptors in gastrointestinal physiology. I. CCK receptors: an exemplary family. Am J Physiol 1998; 274:G607 - G613; PMID: 9575840
   PubMed Web of Science ®Google Scholar
• Smith JP, Rickabaugh CA, McLaughlin PJ, Zagon IS. Cholecystokinin receptors and PANC-1 human pancreatic cancer cells. Am J Physiol 1993; 265:G149 - G155; PMID: 8338163
   PubMedGoogle Scholar
• Smith JP, Liu G, Soundararajan V, McLaughlin PJ, Zagon IS. Identification and characterization of CCK-B/gastrin receptors in human pancreatic cancer cell lines. Am J Physiol 1994; 266:R277 - R283; PMID: 8304551
   PubMed Web of Science ®Google Scholar
• Smith JP, Zagon IS. Cholecystokinin receptors and human pancreatic adenocarcinomas. Int J Pancreatol 1994; 16:243 - 246
   Google Scholar
• Weinberg DS, Ruggeri B, Barber MT, Biswas S, Miknyocki S, Waldman SA. Cholecystokinin A and B receptors are differentially expressed in normal pancreas and pancreatic adenocarcinoma. J Clin Invest 1997; 100:597 - 603; PMID: 9239407; http://dx.doi.org/10.1172/JCI119570
   PubMed Web of Science ®Google Scholar
• Smith JP, Verderame MF, McLaughlin P, Zagon IS. Characterization of the CCK-C (cancer) receptor in human pancreatic cancer. Digestion 1999; 60:401
   Google Scholar
• Smith JP, Verderame MF, McLaughlin P, Martenis M, Ballard E, Zagon IS. Characterization of the CCK-C (cancer) receptor in human pancreatic cancer. Int J Mol Med 2002; 10:689 - 694; PMID: 12429993
   PubMed Web of Science ®Google Scholar
• Hellmich MR, Rui XL, Hellmich HL, Fleming RY, Evers BM, Townsend CM Jr. Human colorectal cancers express a constitutively active cholecystokininB/gastrin receptor that stimulates cell growth. J Biol Chem 2000; 275:32122 - 32128; PMID: 10913157; http://dx.doi.org/10.1074/jbc.M005754200
   PubMed Web of Science ®Google Scholar
• Ding WQ, Kuntz SM, Miller LJ. A misspliced form of the cholecystokinin-B/gastrin receptor in pancreatic carcinoma: role of reduced sellular U2AF35 and a suboptimal 3′-splicing site leading to retention of the fourth intron. Cancer Res 2002; 62:947 - 952; PMID: 11830556
   PubMed Web of Science ®Google Scholar
• Biagini P, Monges G, Vuaroqueaux V, Parriaux D, Cantaloube JF, De Micco P. The human gastrin/cholecystokinin receptors: type B and type C expression in colonic tumors and cell lines. Life Sci 1997; 61:1009 - 1018; PMID: 9296339; http://dx.doi.org/10.1016/S0024-3205(97)00605-X
   PubMed Web of Science ®Google Scholar
• Song I, Brown DR, Wiltshire RN, Gantz I, Trent JM, Yamada T. The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs. Proc Natl Acad Sci USA 1993; 90:9085 - 9089; PMID: 8415658; http://dx.doi.org/10.1073/pnas.90.19.9085
   PubMed Web of Science ®Google Scholar
• Chao C, Goluszko E, Lee YT, Kolokoltsov AA, Davey RA, Uchida T, et al. Constitutively active CCK2 receptor splice variant increases Src-dependent HIF-1 alpha expression and tumor growth. Oncogene 2007; 26:1013 - 1019; PMID: 16909104; http://dx.doi.org/10.1038/sj.onc.1209862
   PubMed Web of Science ®Google Scholar
• Cheng ZJ, Harikumar KG, Ding WQ, Holicky EL, Miller LJ. Analysis of the cellular and molecular mechanisms of trophic action of a misspliced form of the type B cholecystokinin receptor present in colon and pancreatic cancer. Cancer Lett 2005; 222:95 - 105; PMID: 15837546; http://dx.doi.org/10.1016/j.canlet.2004.09.008
   PubMed Web of Science ®Google Scholar
• Laverman P, Roosenburg S, Gotthardt M, Park J, Oyen WJ, de Jong M, et al. Targeting of a CCK(2) receptor splice variant with (111)In-labelled cholecystokinin-8 (CCK8) and (111)In-labelled minigastrin. Eur J Nucl Med Mol Imaging 2008; 35:386 - 392; PMID: 17934729; http://dx.doi.org/10.1007/s00259-007-0604-1
   PubMed Web of Science ®Google Scholar
• Smith JP, Verderame MF, McLaughlin PJ, Zagon IS. Characterization of the CCK-C (cancer) receptor in human pancreatic cancer. Gastroenterology 1999; 116:A1164
   Web of Science ®Google Scholar
• Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958; 53:457 - 481; http://dx.doi.org/10.2307/2281868
   Web of Science ®Google Scholar
• Johnson AD, O'Donnell CJ. An open access database of genome-wide association results. BMC Med Genet 2009; 10:6; PMID: 19161620; http://dx.doi.org/10.1186/1471-2350-10-6
   PubMed Web of Science ®Google Scholar
• Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010; 467:1114 - 1117; PMID: 20981102; http://dx.doi.org/10.1038/nature09515
   PubMed Web of Science ®Google Scholar
• Carter H, Samayoa J, Hruban RH, Karchin R. Prioritization of driver mutations in pancreatic cancer-specific high-throughput annotation of somatic mutations (CHASM). Cancer Biol Ther 2010; 10:582 - 587; PMID: 20581473; http://dx.doi.org/10.4161/cbt.10.6.12537
   PubMed Web of Science ®Google Scholar
• Finn OJ. Cancer immunology. N Engl J Med 2008; 358:2704 - 2715; PMID: 18565863; http://dx.doi.org/10.1056/NEJMra072739
   PubMed Web of Science ®Google Scholar
• Palucka K, Ueno H, Banchereau J. Recent developments in cancer vaccines. J Immunol 2011; 186:1325 - 1331; PMID: 21248270; http://dx.doi.org/10.4049/jimmunol.0902539
   PubMed Web of Science ®Google Scholar
• Brinkman BM. Splice variants as cancer biomarkers. Clin Biochem 2004; 37:584 - 594; PMID: 15234240; http://dx.doi.org/10.1016/j.clinbiochem.2004.05.015
   PubMed Web of Science ®Google Scholar
• Gardina PJ, Clark TA, Shimada B, Staples MK, Yang Q, Veitch J, et al. Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array. BMC Genomics 2006; 7:325; PMID: 17192196; http://dx.doi.org/10.1186/14712164-7-325
   PubMed Web of Science ®Google Scholar
• Long JC, Caceres JF. The SR protein family of splicing factors: master regulators of gene expression. Biochem J 2009; 417:15 - 27; PMID: 19061484; http://dx.doi.org/10.1042/BJ20081501
   PubMed Web of Science ®Google Scholar
• Shepard PJ, Hertel KJ. The SR protein family. Genome Biol 2009; 10:242; PMID: 19857271; http://dx.doi.org/10.1186/gb-2009-10-10-242
   PubMed Web of Science ®Google Scholar