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Research Paper

Identification of Nkx2–3 and TGFB1I1 expression levels as potential biomarkers to predict the effects of FOLFOX4 chemotherapy

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Pages 443-449 | Received 10 Oct 2011, Accepted 09 Jan 2012, Published online: 01 Apr 2012

References

  • Weitz J, Koch M, Debus J, Höhler T, Galle PR, Büchler MW. Colorectal cancer. Lancet 2005; 365:153 - 65; http://dx.doi.org/10.1016/S0140-6736(05)17706-X; PMID: 15639298
  • Arnold CN, Goel A, Blum HE, Boland CR. Molecular pathogenesis of colorectal cancer: implications for molecular diagnosis. Cancer 2005; 104:2035 - 47; http://dx.doi.org/10.1002/cncr.21462; PMID: 16206296
  • Lorenz M, Staib-Sebler E, Hochmuth K, Heinrich S, Gog C, Vetter G, et al. Surgical resection of liver metastases of colorectal carcinoma: short and long-term results. Semin Oncol 2000; 27:Suppl 10 112 - 9; PMID: 11049042
  • Goldberg RM, Sargent DJ, Morton RF, Fuchs CS, Ramanathan RK, Williamson SK, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004; 22:23 - 30; http://dx.doi.org/10.1200/JCO.2004.09.046; PMID: 14665611
  • Grothey A, Sargent D. Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line. J Clin Oncol 2005; 23:9441 - 2; http://dx.doi.org/10.1200/JCO.2005.04.4792; PMID: 16361649
  • Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005; 23:1011 - 27; http://dx.doi.org/10.1200/JCO.2005.06.081; PMID: 15585754
  • Jain RK, Duda DG, Clark JW, Loeffler JS. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 2006; 3:24 - 40; http://dx.doi.org/10.1038/ncponc0403; PMID: 16407877
  • Saltz LB, Clarke S, Díaz-Rubio E, Scheithauer W, Figer A, Wong R, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008; 26:2013 - 9; http://dx.doi.org/10.1200/JCO.2007.14.9930; PMID: 18421054
  • Meyer UA. Pharmacogenetics and adverse drug reactions. Lancet 2000; 356:1667 - 71; http://dx.doi.org/10.1016/S0140-6736(00)03167-6; PMID: 11089838
  • Pullarkat ST, Stoehlmacher J, Ghaderi V, Xiong YP, Ingles SA, Sherrod A, et al. Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J 2001; 1:65 - 70; http://dx.doi.org/10.1038/sj.tpj.6500012; PMID: 11913730
  • Gustavsson B, Kaiser C, Carlsson G, Wettergren Y, Odin E, Lindskog EB, et al. Molecular determinants of efficacy for 5-FU-based treatments in advanced colorectal cancer: mRNA expression for 18 chemotherapy-related genes. Int J Cancer 2009; 124:1220 - 6; http://dx.doi.org/10.1002/ijc.23852; PMID: 19051292
  • Kwon HC, Roh MS, Oh SY, Kim SH, Kim MC, Kim JS, et al. Prognostic value of expression of ERCC1, thymidylate synthase, and glutathione S-transferase P1 for 5-fluorouracil/oxaliplatin chemotherapy in advanced gastric cancer. Ann Oncol 2007; 18:504 - 9; http://dx.doi.org/10.1093/annonc/mdl430; PMID: 17322540
  • Selvakumaran M, Pisarcik DA, Bao R, Yeung AT, Hamilton TC. Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines. Cancer Res 2003; 63:1311 - 6; PMID: 12649192
  • Chang PM, Tzeng CH, Chen PM, Lin JK, Lin TC, Chen WS, et al. ERCC1 codon 118 C-T polymorphism associated with ERCC 1 expression and outcome of FOLFOX-4 treatment in Asian patients with metastatic colorectal carcinoma. J. Cancer Sci 2008; 12:278 - 83
  • Park DJ, Zhang W, Stoehlmacher J, Tsao-Wei D, Groshen S, Gil J, et al. ERCC1 gene polymorphism as a predictor for clinical outcome in advanced colorectal cancer patients treated with platinum-based chemotherapy. Clin Adv Hematol Oncol 2003; 1:162 - 6; PMID: 16224397
  • Ryu JS, Hong YC, Han HS, Lee JE, Kim S, Park YM, et al. Association between polymorphisms of ERCC1 and XPD and survival in non small-cell lung cancer patients treated wide cisplatin combination chemothempy. Lung Cancer 2004; 1:311 - 6; http://dx.doi.org/10.1016/j.lungcan.2003.11.019
  • Su D, Ma S, Liu P, Jiang Z, Lv W, Zhang Y, et al. Genetic polymorphisms and treatment response in advanced non-small cell lung cancer. Lung Cancer 2007; 56:281 - 8; http://dx.doi.org/10.1016/j.lungcan.2006.12.002; PMID: 17222938
  • Viguier J, Boige V, Miquel C, Pocard M, Giraudeau B, Sabourin JC, et al. ERCC1 codon 118 polymorphism is a predictive factor for the tumor response to oxaliplatin/5-fluorouracil combination chemotherapy in patients with advanced colorectal cancer. Clin Cancer Res 2005; 11:6212 - 7; http://dx.doi.org/10.1158/1078-0432.CCR-04-2216; PMID: 16144923
  • Chen J, Xie F, Chen K, Wang D, Jiang H, Li J, et al. ERCC5 promoter polymorphisms at -763 and +25 predict the response to oxaliplatin-based chemotherapy in patients with advanced colorectal cancer. Cancer Biol Ther 2009; 8:1424 - 30; http://dx.doi.org/10.4161/cbt.8.14.8889; PMID: 19458483
  • Suh KW, Kim JH, Kim Y, Kim YB, Lee C, Choi S. Which gene is a dominant predictor of response during FOLFOX chemotherapy for the treatment of metastatic colorectal cancer, the MTHFR or XRCC1 gene?. Ann Surg Oncol 2006; 13:1379 - 85; http://dx.doi.org/10.1245/s10434-006-9112-y; PMID: 17009149
  • Stoehlmacher J, Park DJ, Zhang W, Groshen S, Tsao-Wei DD, Yu MC, et al. Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J Natl Cancer Inst 2002; 94:936 - 42; http://dx.doi.org/10.1093/jnci/94.12.936; PMID: 12072547
  • Braun MS, Richman SD, Quirke P, Daly C, Adlard JW, Elliott F, et al. Predictive biomarkers of chemotherapy efficacy in colorectal cancer: results from the UK MRC FOCUS trial. J Clin Oncol 2008; 26:2690 - 8; http://dx.doi.org/10.1200/JCO.2007.15.5580; PMID: 18509181
  • Koopman M, Venderbosch S, Nagtegaal ID, van Krieken JH, Punt CJ. A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned?. Eur J Cancer 2009; 45:1935 - 49; http://dx.doi.org/10.1016/j.ejca.2009.04.023; PMID: 19473832
  • Hou L, Li Y, Jia YH, Wang B, Xin Y, Ling MY, et al. Molecular mechanism about lymphogenous metastasis of hepatocarcinoma cells in mice. World J Gastroenterol 2001; 7:532 - 6; PMID: 11819823
  • Duggan DJ, Bittner M, Chen Y, Meltzer P, Trent JM. Expression Profiling using DNA microarrays. Nature Gene ties Supplement 1999; 21:10-14.
  • Wen WH, Bernstein L, Lescallett J, Beazer-Barclay Y, Sullivan-Halley J, White M, et al. Comparison of TP53 mutations identified by oligonucleotide microarray and conventional DNA sequence analysis. Cancer Res 2000; 60:2716 - 22; PMID: 10825146
  • Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92:205 - 16; http://dx.doi.org/10.1093/jnci/92.3.205; PMID: 10655437
  • Yu W, Lin Z, Pastor DM, Hegarty JP, Chen X, Kelly AA, et al. Genes regulated by Nkx2-3 in sporadic and inflammatory bowel disease-associated colorectal cancer cell lines. Dig Dis Sci 2010; 55:3171 - 80; http://dx.doi.org/10.1007/s10620-010-1138-0; PMID: 20165982
  • Wang X, Zbou C, Qiu G, Fan J, Tang H, Peng Z. Screening of new tumor suppressor genes in sporadic colorectal cancer patients. Hepatogastroenterology 2008; 55:2039 - 44; PMID: 19260473
  • Cai G, Huang H, Shapiro E, Zhou H, Yeh S, Melamed J, et al. Expression of androgen receptor associated protein 55 (ARA55) in the developing human fetal prostate. J Urol 2005; 173:2190 - 3; http://dx.doi.org/10.1097/01.ju.0000158119.34126.70; PMID: 15879885
  • Yund EE, Hill JA, Keller RS. Hic-5 is required for fetal gene expression and cytoskeletal organization of neonatal cardiac myocytes. J Mol Cell Cardiol 2009; 47:520 - 7; http://dx.doi.org/10.1016/j.yjmcc.2009.06.006; PMID: 19540241
  • Heitzer MD, DeFranco DB. Hic-5/ARA55, a LIM domain-containing nuclear receptor coactivator expressed in prostate stromal cells. Cancer Res 2006; 66:7326 - 33; http://dx.doi.org/10.1158/0008-5472.CAN-05-2379; PMID: 16849583
  • Dabiri G, Tumbarello DA, Turner CE, Van de Water L. Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-beta1 autocrine loop. J Invest Dermatol 2008; 128:2518 - 25; http://dx.doi.org/10.1038/jid.2008.90; PMID: 18401422
  • Dabiri G, Tumbarello DA, Turner CE, Van de Water L. TGF-beta1 slows the growth of pathogenic myofibroblasts through a mechanism requiring the focal adhesion protein, Hic-5. J Invest Dermatol 2008; 128:280 - 91; PMID: 17671518
  • Wang H, Song K, Krebs TL, Yang J, Danielpour D. Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55. Oncogene 2008; 27:6791 - 805; http://dx.doi.org/10.1038/onc.2008.291; PMID: 18762808
  • Stavit Drori1, Geoffrey D. Girnun, Liqiang Tou, Jeffrey D. Szwaya, Elisabetta Mueller, Xia Kia, et al. Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev 2005; 19(3): 361-375.
  • Osada M, Ohmori T, Yatomi Y, Satoh K, Hosogaya S, Ozaki Y. Involvement of Hic-5 in platelet activation: integrin alphaIIbbeta3-dependent tyrosine phosphorylation and association with proline-rich tyrosine kinase 2. Biochem J 2001; 355:691 - 7; PMID: 11311131
  • Nishiya N, Tachibana K, Shibanuma M, Mashimo J-I. Kiyoshi Nose1. Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase. Mol Cell Biol 2001; 21:5331 - 45; http://dx.doi.org/10.1128/MCB.21.16.5332-5345.2001
  • Shibanuma M, Iwabuchi Y, Nose K. Possible involvement of hic-5, a focal adhesion protein, in the differentiation of C2C12 myoblasts. Cell Struct Funct 2002; 27:21 - 7; http://dx.doi.org/10.1247/csf.27.21; PMID: 11937715
  • Gao ZL, Deblis R, Glenn H, Schwartz LM. Differential roles of HIC-5 isoforms in the regulation of cell death and myotube formation during myogenesis. Exp Cell Res 2007; 313:4000 - 14; http://dx.doi.org/10.1016/j.yexcr.2007.05.023; PMID: 17935713
  • Shibanuma M, Kim-Kaneyama JR, Sato S, Nose K. A LIM protein, Hic-5, functions as a potential coactivator for Sp1. J Cell Biochem 2004; 91:633 - 45; http://dx.doi.org/10.1002/jcb.10754; PMID: 14755691
  • Carneiro AM, Blakely RD. Serotonin-, protein kinase C-, and Hic-5-associated redistribution of the platelet serotonin transporter. J Biol Chem 2006; 281:24769 - 80; http://dx.doi.org/10.1074/jbc.M603877200; PMID: 16803896
  • Hetey SE, Lalonde DP, Turner CE. Tyrosine-phosphorylated Hic-5 inhibits epidermal growth factor-induced lamellipodia formation. Exp Cell Res 2005; 311:147 - 56; http://dx.doi.org/10.1016/j.yexcr.2005.08.011; PMID: 16183059
  • Shibanuma M, Mashimo J, Kuroki T, Nose K. Characterization of the TGF beta 1-inducible hic-5 gene that encodes a putative novel zinc finger protein and its possible involvement in cellular senescence. J Biol Chem 1994; 269:26767 - 74; PMID: 7929412
  • Heitzer MD, DeFranco DB. Hic-5/ARA55: a prostate stroma-specific AR coactivator. Steroids 2007; 72:218 - 20; http://dx.doi.org/10.1016/j.steroids.2006.11.010; PMID: 17166536
  • Fujimoto N, Mizokami A, Harada S, Matsumoto T. Different expression of androgen receptor coactivators in human prostate. Urology 2001; 58:289 - 94; http://dx.doi.org/10.1016/S0090-4295(01)01117-7; PMID: 11489729
  • Rahman MM, Miyamoto H, Lardy H, Chang C. Inactivation of androgen receptor coregulator ARA55 inhibits androgen receptor activity and agonist effect of antiandrogens in prostate cancer cells. Proc Natl Acad Sci U S A 2003; 100:5124 - 9; http://dx.doi.org/10.1073/pnas.0530097100; PMID: 12700349
  • Mestayer1 C, Blanchère M, Jaubert F, Dufour B, Mowszowicz I. Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines. Prostate 2003; 56:191 - 200
  • Bertucci F, Salas S, Eysteries S, Nasser V, Finetti P, Ginestier C, et al. Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters. Oncogene 2004; 23:1377 - 91; http://dx.doi.org/10.1038/sj.onc.1207262; PMID: 14973550
  • Cui W, Wang X, Liu YC, Wan YL, Guo HJ, Zhu J. [Expression of HIC-5/ARA55 in colonrectal cancer and its mechanisms of action]. Beijing Da Xue Xue Bao 2006; 38:280 - 3; PMID: 16778972

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