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Research Paper

E2F-1 lacking the transcriptional activity domain induces autophagy

, , , , , & show all
Pages 1091-1101 | Received 03 Apr 2012, Accepted 17 Jun 2012, Published online: 24 Jul 2012

References

  • Soengas MS, Lowe SW. Apoptosis and melanoma chemoresistance. Oncogene 2003; 22:3138 - 51; http://dx.doi.org/10.1038/sj.onc.1206454; PMID: 12789290
  • Hersey P, Zhang XD. Overcoming resistance of cancer cells to apoptosis. J Cell Physiol 2003; 196:9 - 18; http://dx.doi.org/10.1002/jcp.10256; PMID: 12767037
  • Zhang XD, Wu JJ, Gillespie S, Borrow J, Hersey P. Human melanoma cells selected for resistance to apoptosis by prolonged exposure to tumor necrosis factor-related apoptosis-inducing ligand are more vulnerable to necrotic cell death induced by cisplatin. Clin Cancer Res 2006; 12:1355 - 64; http://dx.doi.org/10.1158/1078-0432.CCR-05-2084; PMID: 16489094
  • Xanthoudakis S, Nicholson DW. Heat-shock proteins as death determinants. Nat Cell Biol 2000; 2:E163 - 5; http://dx.doi.org/10.1038/35023643; PMID: 10980714
  • Beere HM, Green DR. Stress management - heat shock protein-70 and the regulation of apoptosis. Trends Cell Biol 2001; 11:6 - 10; http://dx.doi.org/10.1016/S0962-8924(00)01874-2; PMID: 11146277
  • Deveraux QL, Reed JC. IAP family proteins--suppressors of apoptosis. Genes Dev 1999; 13:239 - 52; http://dx.doi.org/10.1101/gad.13.3.239; PMID: 9990849
  • Gozuacik D, Kimchi A. Autophagy and cell death. Curr Top Dev Biol 2007; 78:217 - 45; http://dx.doi.org/10.1016/S0070-2153(06)78006-1; PMID: 17338918
  • Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004; 304:1500 - 2; http://dx.doi.org/10.1126/science.1096645; PMID: 15131264
  • Yu L, Wan F, Dutta S, Welsh S, Liu Z, Freundt E, et al. Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci U S A 2006; 103:4952 - 7; http://dx.doi.org/10.1073/pnas.0511288103; PMID: 16547133
  • Newman RA, Kondo Y, Yokoyama T, Dixon S, Cartwright C, Chan D, et al. Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside. Integr Cancer Ther 2007; 6:354 - 64; http://dx.doi.org/10.1177/1534735407309623; PMID: 18048883
  • Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2001; 2:211 - 6; http://dx.doi.org/10.1038/35056522; PMID: 11265251
  • Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6:463 - 77; http://dx.doi.org/10.1016/S1534-5807(04)00099-1; PMID: 15068787
  • Tracy K, Dibling BC, Spike BT, Knabb JR, Schumacker P, Macleod KF. BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Mol Cell Biol 2007; 27:6229 - 42; http://dx.doi.org/10.1128/MCB.02246-06; PMID: 17576813
  • Kondo Y, Kanzawa T, Sawaya R, Kondo S. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 2005; 5:726 - 34; http://dx.doi.org/10.1038/nrc1692; PMID: 16148885
  • Bursch W, Ellinger A, Kienzl H, Török L, Pandey S, Sikorska M, et al. Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 1996; 17:1595 - 607; http://dx.doi.org/10.1093/carcin/17.8.1595; PMID: 8761415
  • Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000; 290:1717 - 21; http://dx.doi.org/10.1126/science.290.5497.1717; PMID: 11099404
  • Polager S, Ofir M, Ginsberg D. E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene 2008; 27:4860 - 4; http://dx.doi.org/10.1038/onc.2008.117; PMID: 18408756
  • Rodriguez-Rocha H, Gomez-Gutierrez JG, Garcia-Garcia A, Rao XM, Chen L, McMasters KM, et al. Adenoviruses induce autophagy to promote virus replication and oncolysis. Virology 2011; 416:9 - 15; http://dx.doi.org/10.1016/j.virol.2011.04.017; PMID: 21575980
  • Baehrecke EH. Autophagy: dual roles in life and death?. Nat Rev Mol Cell Biol 2005; 6:505 - 10; http://dx.doi.org/10.1038/nrm1666; PMID: 15928714
  • Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008; 4:151 - 75; PMID: 18188003
  • Sala A, Nicolaides NC, Engelhard A, Bellon T, Lawe DC, Arnold A, et al. Correlation between E2F-1 requirement in the S phase and E2F-1 transactivation of cell cycle-related genes in human cells. Cancer Res 1994; 54:1402 - 6; PMID: 8137237
  • Yang XH, Sladek TL. Overexpression of the E2F-1 transcription factor gene mediates cell transformation. Gene Expr 1995; 4:195 - 204; PMID: 7787412
  • Xu G, Livingston DM, Krek W. Multiple members of the E2F transcription factor family are the products of oncogenes. Proc Natl Acad Sci U S A 1995; 92:1357 - 61; http://dx.doi.org/10.1073/pnas.92.5.1357; PMID: 7877982
  • Shan B, Lee WH. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol Cell Biol 1994; 14:8166 - 73; PMID: 7969153
  • Johnson DG, Cress WD, Jakoi L, Nevins JR. Oncogenic capacity of the E2F1 gene. Proc Natl Acad Sci U S A 1994; 91:12823 - 7; http://dx.doi.org/10.1073/pnas.91.26.12823; PMID: 7809128
  • Bandara LR, Buck VM, Zamanian M, Johnston LH, La Thangue NB. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J 1993; 12:4317 - 24; PMID: 8223441
  • Gomez-Gutierrez JG, Rao XM, Garcia-Garcia A, Hao H, McMasters KM, Zhou HS. Developing adenoviral vectors encoding therapeutic genes toxic to host cells: comparing binary and single-inducible vectors expressing truncated E2F-1. Virology 2010; 397:337 - 45; http://dx.doi.org/10.1016/j.virol.2009.11.021; PMID: 20003994
  • Gomez-Gutierrez JG, Garcia-Garcia A, Hao H, Rao XM, Montes de Oca-Luna R, Zhou HS, et al. Adenovirus-mediated expression of truncated E2F-1 suppresses tumor growth in vitro and in vivo. Cancer 2010; 116:4420 - 32; http://dx.doi.org/10.1002/cncr.25322; PMID: 20549818
  • Ketteler R, Seed B. Quantitation of autophagy by luciferase release assay. Autophagy 2008; 4:801 - 6; PMID: 18641457
  • Ketteler R, Sun Z, Kovacs KF, He WW, Seed B. A pathway sensor for genome-wide screens of intracellular proteolytic cleavage. Genome Biol 2008; 9:R64; http://dx.doi.org/10.1186/gb-2008-9-4-r64; PMID: 18387192
  • Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19:5720 - 8; http://dx.doi.org/10.1093/emboj/19.21.5720; PMID: 11060023
  • Tanida I, Minematsu-Ikeguchi N, Ueno T, Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy 2005; 1:84 - 91; http://dx.doi.org/10.4161/auto.1.2.1697; PMID: 16874052
  • Mizushima N, Yamamoto A, Hatano M, Kobayashi Y, Kabeya Y, Suzuki K, et al. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol 2001; 152:657 - 68; http://dx.doi.org/10.1083/jcb.152.4.657; PMID: 11266458
  • Reef S, Zalckvar E, Shifman O, Bialik S, Sabanay H, Oren M, et al. A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death. Mol Cell 2006; 22:463 - 75; http://dx.doi.org/10.1016/j.molcel.2006.04.014; PMID: 16713577
  • Tyler MA, Ulasov IV, Lesniak MS. Cancer cell death by design: apoptosis, autophagy and glioma virotherapy. Autophagy 2009; 5:856 - 7; PMID: 19430207
  • Dong YB, Yang HL, Elliott MJ, McMasters KM. Adenovirus-mediated E2F-1 gene transfer sensitizes melanoma cells to apoptosis induced by topoisomerase II inhibitors. Cancer Res 2002; 62:1776 - 83; PMID: 11912154
  • Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, et al. The role of autophagy during the early neonatal starvation period. Nature 2004; 432:1032 - 6; http://dx.doi.org/10.1038/nature03029; PMID: 15525940
  • Mizushima N, Yoshimori T, Ohsumi Y. Role of the Apg12 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2003; 35:553 - 61; http://dx.doi.org/10.1016/S1357-2725(02)00343-6; PMID: 12672448
  • Alonso MM, Jiang H, Yokoyama T, Xu J, Bekele NB, Lang FF, et al. Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death. Mol Ther 2008; 16:487 - 93; http://dx.doi.org/10.1038/sj.mt.6300400; PMID: 18253154
  • Byun JY, Yoon CH, An S, Park IC, Kang CM, Kim MJ, et al. The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras. Carcinogenesis 2009; 30:1880 - 8; http://dx.doi.org/10.1093/carcin/bgp235; PMID: 19783847
  • Kim MJ, Woo SJ, Yoon CH, Lee JS, An S, Choi YH, et al. Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation. J Biol Chem 2011; 286:12924 - 32; http://dx.doi.org/10.1074/jbc.M110.138958; PMID: 21300795
  • Young MM, Takahashi Y, Khan O, Park S, Hori T, Yun J, et al. Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. J Biol Chem 2012; 287:12455 - 68; http://dx.doi.org/10.1074/jbc.M111.309104; PMID: 22362782
  • Zhang JQ, Li YM, Liu T, He WT, Chen YT, Chen XH, et al. Antitumor effect of matrine in human hepatoma G2 cells by inducing apoptosis and autophagy. World J Gastroenterol 2010; 16:4281 - 90; http://dx.doi.org/10.3748/wjg.v16.i34.4281; PMID: 20818811
  • Huang SW, Liu KT, Chang CC, Chen YJ, Wu CY, Tsai JJ, et al. Imiquimod simultaneously induces autophagy and apoptosis in human basal cell carcinoma cells. Br J Dermatol 2010; 163:310 - 20; http://dx.doi.org/10.1111/j.1365-2133.2010.09827.x; PMID: 20426785
  • Archer CR, Koomoa DL, Mitsunaga EM, Clerc J, Shimizu M, Kaiser M, et al. Syrbactin class proteasome inhibitor-induced apoptosis and autophagy occurs in association with p53 accumulation and Akt/PKB activation in neuroblastoma. Biochem Pharmacol 2010; 80:170 - 8; http://dx.doi.org/10.1016/j.bcp.2010.03.031; PMID: 20362557
  • Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L, et al. Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 2006; 8:1124 - 32; http://dx.doi.org/10.1038/ncb1482; PMID: 16998475
  • Codogno P, Meijer AJ. Atg5: more than an autophagy factor. Nat Cell Biol 2006; 8:1045 - 7; http://dx.doi.org/10.1038/ncb1006-1045; PMID: 17013414
  • Ko SH, Ueno T, Yoshimoto Y, Yoo JS, Abdel-Wahab OI, Abdel-Wahab Z, et al. Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity. Clin Cancer Res 2006; 12:289 - 97; http://dx.doi.org/10.1158/1078-0432.CCR-05-0210; PMID: 16397054
  • Resnitzky D, Gossen M, Bujard H, Reed SI. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol Cell Biol 1994; 14:1669 - 79; PMID: 8114703
  • Gossen M, Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci U S A 1992; 89:5547 - 51; http://dx.doi.org/10.1073/pnas.89.12.5547; PMID: 1319065
  • Bett AJ, Haddara W, Prevec L, Graham FL. An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc Natl Acad Sci U S A 1994; 91:8802 - 6; http://dx.doi.org/10.1073/pnas.91.19.8802; PMID: 8090727
  • Gomez-Gutierrez JG, Souza V, Hao HY, Montes de Oca-Luna R, Dong YB, Zhou HS, et al. Adenovirus-mediated gene transfer of FKHRL1 triple mutant efficiently induces apoptosis in melanoma cells. Cancer Biol Ther 2006; 5:875 - 83; http://dx.doi.org/10.4161/cbt.5.7.2911; PMID: 16861905

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