886
Views
13
CrossRef citations to date
0
Altmetric
Research Paper

Preliminary pharmacology of galactosylated chitosan/5-fluorouracil nanoparticles and its inhibition of hepatocellular carcinoma in mice

, , , , , , , , , , & show all
Pages 1407-1416 | Received 22 Apr 2012, Accepted 29 Aug 2012, Published online: 06 Sep 2012

References

  • Kim NH, Kim SN, Oh JS, Lee S, Kim YK. Anti-mitotic potential of 7-diethylamino-3(2′-benzoxazolyl)-coumarin in 5-fluorouracil-resistant human gastric cancer cell line SNU620/5-FU. Biochem Biophys Res Commun 2012; 418:616 - 21; http://dx.doi.org/10.1016/j.bbrc.2012.01.049; PMID: 22301191
  • Hsieh CH, Liu CY, Hsieh YJ, Tai HC, Wang LY, Tsai TH, et al. Matrix metalloproteinase-8 mediates the unfavorable systemic impact of local irradiation on pharmacokinetics of anti-cancer drug 5-Fluorouracil. PLoS One 2011; 6:e21000; http://dx.doi.org/10.1371/journal.pone.0021000; PMID: 21695264
  • Namikawa T, Fukudome I, Kitagawa H, Okabayashi T, Kobayashi M, Hanazaki K. Plasma diamine oxidase activity is a useful biomarker for evaluating gastrointestinal tract toxicities during chemotherapy with oral fluorouracil anti-cancer drugs in patients with gastric cancer. Oncology 2012; 82:147 - 52; http://dx.doi.org/10.1159/000336799; PMID: 22433290
  • Sakata Y, Komatsu Y, Takagi S, Saitoh S, Itoh T, Suzuki H, et al. Randomized controlled study of mitomycin C/carboquone/5-fluorouracil/OK-432 (MQ-F-OK) therapy and mitomycin C/5-fluorouracil/doxorubicin (FAM) therapy against advanced liver cancer. Cancer Chemother Pharmacol 1989; 23:Suppl S9 - 12; http://dx.doi.org/10.1007/BF00647230; PMID: 2647315
  • Kanetaka K, Enjoji A, Furui J, Nagata Y, Fujioka H, Shiogama T, et al, The Nagasaki Study Group for Digestive Organ Cancer Chemotherapy. Effects of Intermittent 5-Fluorouracil and Low-dose Cisplatin Therapy on Advanced and Recurrent Gastric Cancer. Anticancer Res 2012; 32:3495 - 9; PMID: 22843936
  • Sinha VR, Honey. Critical aspects in rationale design of fluorouracil-based adjuvant therapies for the management of colon cancer. Crit Rev Ther Drug Carrier Syst 2012; 29:89 - 148; http://dx.doi.org/10.1615/CritRevTherDrugCarrierSyst.v29.i2.10; PMID: 22577701
  • Kurosaki I, Kawachi Y, Nihei K, Tsuchiya Y, Aono T, Yokoyama N, et al. Liver perfusion chemotherapy with 5-Fluorouracil followed by systemic gemcitabine administration for resected pancreatic cancer: preliminary results of a prospective phase 2 study. Pancreas 2009; 38:161 - 7; http://dx.doi.org/10.1097/MPA.0b013e31818815f7; PMID: 18797423
  • Zhao HY, Huang H, Hu ZH, Huang Y, Lin SX, Tian Y, et al. Evaluations of biomarkers associated with sensitivity to 5-fluorouracil and taxanes for recurrent/advanced breast cancer patients treated with capecitabine-based first-line chemotherapy. Anticancer Drugs 2012; 23:534 - 42; http://dx.doi.org/10.1097/CAD.0b013e32834f7ef4; PMID: 22481060
  • White RM. Correct fluorouracil (5-FU) half-life comparator for a 5-FU prodrug plus a dihydropyrimidine dehydrogenase inhibitor. J Clin Oncol 2001; 19:2970; PMID: 11387375
  • Dikken C, Sitzia J. Patients’ experiences of chemotherapy: side-effects associated with 5-fluorouracil + folinic acid in the treatment of colorectal cancer. J Clin Nurs 1998; 7:371 - 9; http://dx.doi.org/10.1046/j.1365-2702.1998.00159.x; PMID: 9830978
  • Wettergren Y, Carlsson G, Odin E, Gustavsson B. Pretherapeutic uracil and dihydrouracil levels of colorectal cancer patients are associated with sex and toxic side effects during adjuvant 5-fluorouracil-based chemotherapy. Cancer 2012; 118:2935 - 43; http://dx.doi.org/10.1002/cncr.26595; PMID: 22020693
  • Wilson B, Ambika TV, Dharmesh Kumar Patel R, Jenita JL, Priyadarshini SR. Nanoparticles based on albumin: Preparation, characterization and the use for 5-flurouracil delivery. Int J Biol Macromol 2012; http://dx.doi.org/10.1016/j.ijbiomac.2012.07.014; PMID: 22820011
  • Chandy T, Das GS, Rao GH. 5-Fluorouracil-loaded chitosan coated polylactic acid microspheres as biodegradable drug carriers for cerebral tumours. J Microencapsul 2000; 17:625 - 38; http://dx.doi.org/10.1080/026520400417676; PMID: 11038121
  • Zhu L, Ma J, Jia N, Zhao Y, Shen H. Chitosan-coated magnetic nanoparticles as carriers of 5-fluorouracil: preparation, characterization and cytotoxicity studies. Colloids Surf B Biointerfaces 2009; 68:1 - 6; http://dx.doi.org/10.1016/j.colsurfb.2008.07.020; PMID: 19013060
  • Lai LF, Guo HX. Preparation of new 5-fluorouracil-loaded zein nanoparticles for liver targeting. Int J Pharm 2011; 404:317 - 23; http://dx.doi.org/10.1016/j.ijpharm.2010.11.025; PMID: 21094232
  • Lai LF, Guo HX. Preparation of new 5-fluorouracil-loaded zein nanoparticles for liver targeting. Int J Pharm 2011; 404:317 - 23; http://dx.doi.org/10.1016/j.ijpharm.2010.11.025; PMID: 21094232
  • Kim TH, Park IK, Nah JW, Choi YJ, Cho CS. Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier. Biomaterials 2004; 25:3783 - 92; http://dx.doi.org/10.1016/j.biomaterials.2003.10.063; PMID: 15020154
  • Fallon RJ, Danaher M, Saxena A. The asialoglycoprotein receptor is associated with a tyrosine kinase in HepG2 cells. J Biol Chem 1994; 269:26626 - 9; PMID: 7929394
  • Cheng M, Li Q, Wan T, Hong X, Chen H, He B, et al. Synthesis and efficient hepatocyte targeting of galactosylated chitosan as a gene carrier in vitro and in vivo. J Biomed Mater Res B Appl Biomater 2011; 99:70 - 80; http://dx.doi.org/10.1002/jbm.b.31873; PMID: 21656667
  • Chang CJ, Chen YH, Huang KW, Cheng HW, Chan SF, Tai KF, et al. Combined GM-CSF and IL-12 gene therapy synergistically suppresses the growth of orthotopic liver tumors. Hepatology 2007; 45:746 - 54; http://dx.doi.org/10.1002/hep.21560; PMID: 17326190
  • Wang XH, Liu BR, Qu B, Xing H, Gao SL, Yin JM, et al. Silencing STAT3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: potential uses for gene therapy. Neoplasma 2011; 58:158 - 71; http://dx.doi.org/10.4149/neo_2011_02_158; PMID: 21275467
  • Dung TD, Chang HC, Chen CY, Peng WH, Tsai CH, Tsai FJ, et al. Zanthoxylum avicennae extracts induce cell apoptosis through protein phosphatase 2A activation in HA22T human hepatocellular carcinoma cells and block tumor growth in xenografted nude mice. Int J Mol Med 2011; 28:927 - 36; PMID: 21874223
  • Khurana A, McKean H, Kim H, Kim SH, McGuire J, Roberts LR, et al. Silencing of HSulf-2 expression in MCF10DCIS.com cells attenuate ductal carcinoma in situ progression to invasive ductal carcinoma in vivo. Breast Cancer Res 2012; 14:R43; http://dx.doi.org/10.1186/bcr3140; PMID: 22410125
  • Li DC, Zhong XK, Zeng ZP, Jiang JG, Li L, Zhao MM, et al. Application of targeted drug delivery system in Chinese medicine. J Control Release 2009; 138:103 - 12; http://dx.doi.org/10.1016/j.jconrel.2009.05.008; PMID: 19433120
  • Whitesides GM. The ‘right’ size in nanobiotechnology. Nat Biotechnol 2003; 21:1161 - 5; http://dx.doi.org/10.1038/nbt872; PMID: 14520400
  • Marcucci F, Lefoulon F. Active targeting with particulate drug carriers in tumor therapy: fundamentals and recent progress. Drug Discov Today 2004; 9:219 - 28; http://dx.doi.org/10.1016/S1359-6446(03)02988-X; PMID: 14980540
  • Alex SM, Rekha MR, Sharma CP. Spermine grafted galactosylated chitosan for improved nanoparticle mediated gene delivery. Int J Pharm 2011; 410:125 - 37; http://dx.doi.org/10.1016/j.ijpharm.2011.02.067; PMID: 21396993
  • Jiang H, Wu H, Xu YL, Wang JZ, Zeng Y. Preparation of galactosylated chitosan/tripolyphosphate nanoparticles and application as a gene carrier for targeting SMMC7721 cells. J Biosci Bioeng 2011; 111:719 - 24; http://dx.doi.org/10.1016/j.jbiosc.2011.01.012; PMID: 21334972
  • Kim JH, Kim YS, Park K, Lee S, Nam HY, Min KH, et al. Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice. J Control Release 2008; 127:41 - 9; http://dx.doi.org/10.1016/j.jconrel.2007.12.014; PMID: 18234388
  • Yu BT, Sun X, Zhang ZR. Enhanced liver targeting by synthesis of N1-stearyl-5-Fu and incorporation into solid lipid nanoparticles. Arch Pharm Res 2003; 26:1096 - 101; http://dx.doi.org/10.1007/BF02994764; PMID: 14723346
  • Yan C, Gu J, Guo Y, Chen D. In vivo biodistribution for tumor targeting of 5-fluorouracil (5-FU) loaded N-succinyl-chitosan (Suc-Chi) nanoparticles. Yakugaku Zasshi 2010; 130:801 - 4; http://dx.doi.org/10.1248/yakushi.130.801; PMID: 20519858
  • Sasaki K, Tsuno NH, Sunami E, Tsurita G, Kawai K, Okaji Y, et al. Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. BMC Cancer 2010; 10:370; http://dx.doi.org/10.1186/1471-2407-10-370; PMID: 20630104
  • Huang Z, Guo KJ, Guo RX, He SG. Effects of 5-fluouracil combined with sulfasalazine on human pancreatic carcinoma cell line BxPC-3 proliferation and apoptosis in vitro. Hepatobiliary Pancreat Dis Int 2007; 6:312 - 20; PMID: 17548258

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.