CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion

References

• el-Deiry WS. Regulation of p53 downstream genes. Semin Cancer Biol 1998; 8:345 - 57; http://dx.doi.org/10.1006/scbi.1998.0097; PMID: 10101800
   PubMed Web of Science ®Google Scholar
• Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature 2000; 408:307 - 10; http://dx.doi.org/10.1038/35042675; PMID: 11099028
   PubMed Web of Science ®Google Scholar
• Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A, et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 1997; 90:809 - 19; http://dx.doi.org/10.1016/S0092-8674(00)80540-1; PMID: 9288759
   PubMed Web of Science ®Google Scholar
• Osada M, Ohba M, Kawahara C, Ishioka C, Kanamaru R, Katoh I, et al. Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nat Med 1998; 4:839 - 43; http://dx.doi.org/10.1038/nm0798-839; PMID: 9662378
   PubMed Web of Science ®Google Scholar
• Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dötsch V, et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 1998; 2:305 - 16; http://dx.doi.org/10.1016/S1097-2765(00)80275-0; PMID: 9774969
   PubMed Web of Science ®Google Scholar
• Dötsch V, Bernassola F, Coutandin D, Candi E, Melino G. p63 and p73, the ancestors of p53. Cold Spring Harb Perspect Biol 2010; 2:a004887; http://dx.doi.org/10.1101/cshperspect.a004887; PMID: 20484388
   PubMed Web of Science ®Google Scholar
• Barbieri CE, Pietenpol JA. p53 family members: similar biochemistry, different biology. Cancer Biol Ther 2005; 4:419 - 20; http://dx.doi.org/10.4161/cbt.4.4.1760; PMID: 15908776
   PubMed Web of Science ®Google Scholar
• Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, et al. The mutational landscape of head and neck squamous cell carcinoma. Science 2011; 333:1157 - 60; http://dx.doi.org/10.1126/science.1208130; PMID: 21798893
   PubMed Web of Science ®Google Scholar
• Zhang J, Chen X. The p53 family: prospect for cancer gene therapy. Cancer Biol Ther 2007; 6:116 - 8; http://dx.doi.org/10.4161/cbt.6.1.3790; PMID: 17612008
   PubMed Web of Science ®Google Scholar
• Chen F, Wang W, El-Deiry WS. Current strategies to target p53 in cancer. Biochem Pharmacol 2010; 80:724 - 30; http://dx.doi.org/10.1016/j.bcp.2010.04.031; PMID: 20450892
   PubMed Web of Science ®Google Scholar
• Leslie M. Brothers in arms against cancer. Science 2011; 331:1551 - 2; http://dx.doi.org/10.1126/science.331.6024.1551; PMID: 21436441
   PubMed Web of Science ®Google Scholar
• Lu C, Wang W, El-Deiry WS. Non-genotoxic anti-neoplastic effects of ellipticine derivative NSC176327 in p53-deficient human colon carcinoma cells involve stimulation of p73. Cancer Biol Ther 2008; 7:2039 - 46; http://dx.doi.org/10.4161/cbt.7.12.7461; PMID: 19106635
   PubMed Web of Science ®Google Scholar
• Sasaki Y, Negishi H, Koyama R, Anbo N, Ohori K, Idogawa M, et al. p53 family members regulate the expression of the apolipoprotein D gene. J Biol Chem 2009; 284:872 - 83; http://dx.doi.org/10.1074/jbc.M807185200; PMID: 19001418
   PubMed Web of Science ®Google Scholar
• Walia V, Ding M, Kumar S, Nie D, Premkumar LS, Elble RC. hCLCA2 Is a p53-Inducible Inhibitor of Breast Cancer Cell Proliferation. Cancer Res 2009; 69:6624 - 32; http://dx.doi.org/10.1158/0008-5472.CAN-08-4101; PMID: 19654313
   PubMed Web of Science ®Google Scholar
• el-Deiry WS, Kern SE, Pietenpol JA, Kinzler KW, Vogelstein B. Definition of a consensus binding site for p53. Nat Genet 1992; 1:45 - 9; http://dx.doi.org/10.1038/ng0492-45; PMID: 1301998
   PubMed Web of Science ®Google Scholar
• Sasaki Y, Ishida S, Morimoto I, Yamashita T, Kojima T, Kihara C, et al. The p53 family member genes are involved in the Notch signal pathway. J Biol Chem 2002; 277:719 - 24; http://dx.doi.org/10.1074/jbc.M108080200; PMID: 11641404
   PubMed Web of Science ®Google Scholar
• Bustin SA, Li SR, Dorudi S. Expression of the Ca2+-activated chloride channel genes CLCA1 and CLCA2 is downregulated in human colorectal cancer. DNA Cell Biol 2001; 20:331 - 8; http://dx.doi.org/10.1089/10445490152122442; PMID: 11445004
   PubMed Web of Science ®Google Scholar
• Li X, Cowell JK, Sossey-Alaoui K. CLCA2 tumour suppressor gene in 1p31 is epigenetically regulated in breast cancer. Oncogene 2004; 23:1474 - 80; http://dx.doi.org/10.1038/sj.onc.1207249; PMID: 14973555
   PubMed Web of Science ®Google Scholar
• Hoffmann EK. Ion channels involved in cell volume regulation: effects on migration, proliferation, and programmed cell death in non adherent EAT cells and adherent ELA cells. Cell Physiol Biochem 2011; 28:1061 - 78; http://dx.doi.org/10.1159/000335843; PMID: 22178996
   PubMed Web of Science ®Google Scholar
• Lang F, Föller M, Lang K, Lang P, Ritter M, Vereninov A, et al. Cell volume regulatory ion channels in cell proliferation and cell death. Methods Enzymol 2007; 428:209 - 25; http://dx.doi.org/10.1016/S0076-6879(07)28011-5; PMID: 17875419
   PubMed Web of Science ®Google Scholar
• Ransom CB, O’Neal JT, Sontheimer H. Volume-activated chloride currents contribute to the resting conductance and invasive migration of human glioma cells. J Neurosci 2001; 21:7674 - 83; PMID: 11567057
   PubMed Web of Science ®Google Scholar
• Abdel-Ghany M, Cheng HC, Elble RC, Pauli BU. Focal adhesion kinase activated by beta(4) integrin ligation to mCLCA1 mediates early metastatic growth. J Biol Chem 2002; 277:34391 - 400; http://dx.doi.org/10.1074/jbc.M205307200; PMID: 12110680
   PubMed Web of Science ®Google Scholar
• Parsons JT. Focal adhesion kinase: the first ten years. J Cell Sci 2003; 116:1409 - 16; http://dx.doi.org/10.1242/jcs.00373; PMID: 12640026
   PubMed Web of Science ®Google Scholar
• Hamadi A, Bouali M, Dontenwill M, Stoeckel H, Takeda K, Rondé P. Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397. J Cell Sci 2005; 118:4415 - 25; http://dx.doi.org/10.1242/jcs.02565; PMID: 16159962
   PubMed Web of Science ®Google Scholar
• Sieg DJ, Hauck CR, Schlaepfer DD. Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migration. J Cell Sci 1999; 112:2677 - 91; PMID: 10413676
   PubMed Web of Science ®Google Scholar
• Slack-Davis JK, Martin KH, Tilghman RW, Iwanicki M, Ung EJ, Autry C, et al. Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem 2007; 282:14845 - 52; http://dx.doi.org/10.1074/jbc.M606695200; PMID: 17395594
   PubMed Web of Science ®Google Scholar
• Golubovskaya VM, Finch R, Kweh F, Massoll NA, Campbell-Thompson M, Wallace MR, et al. p53 regulates FAK expression in human tumor cells. Mol Carcinog 2008; 47:373 - 82; http://dx.doi.org/10.1002/mc.20395; PMID: 17999388
   PubMed Web of Science ®Google Scholar
• Schlaepfer DD, Mitra SK. Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev 2004; 14:92 - 101; http://dx.doi.org/10.1016/j.gde.2003.12.002; PMID: 15108811
   PubMed Web of Science ®Google Scholar
• Siesser PM, Hanks SK. The signaling and biological implications of FAK overexpression in cancer. Clin Cancer Res 2006; 12:3233 - 7; http://dx.doi.org/10.1158/1078-0432.CCR-06-0456; PMID: 16740741
   PubMed Web of Science ®Google Scholar
• Golubovskaya VM, Kweh FA, Cance WG. Focal adhesion kinase and cancer. Histol Histopathol 2009; 24:503 - 10; PMID: 19224453
   PubMed Web of Science ®Google Scholar
• Tanikawa C, Nakagawa H, Furukawa Y, Nakamura Y, Matsuda K. CLCA2 as a p53-inducible senescence mediator. Neoplasia 2012; 14:141 - 9; PMID: 22431922
   PubMed Web of Science ®Google Scholar
• Golubovskaya VM, Conway-Dorsey K, Edmiston SN, Tse CK, Lark AA, Livasy CA, et al. FAK overexpression and p53 mutations are highly correlated in human breast cancer. Int J Cancer 2009; 125:1735 - 8; http://dx.doi.org/10.1002/ijc.24486; PMID: 19521985
   PubMed Web of Science ®Google Scholar
• Lim ST, Chen XL, Lim Y, Hanson DA, Vo TT, Howerton K, et al. Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation. Mol Cell 2008; 29:9 - 22; http://dx.doi.org/10.1016/j.molcel.2007.11.031; PMID: 18206965
   PubMed Web of Science ®Google Scholar
• Elble RC, Pauli BU. Tumor suppression by a proapoptotic calcium-activated chloride channel in mammary epithelium. J Biol Chem 2001; 276:40510 - 7; http://dx.doi.org/10.1074/jbc.M104821200; PMID: 11483609
   PubMed Web of Science ®Google Scholar
• Oshima Y, Sasaki Y, Negishi H, Idogawa M, Toyota M, Yamashita T, et al. Antitumor effect of adenovirus-mediated p53 family gene transfer on osteosarcoma cell lines. Cancer Biol Ther 2007; 6:1058 - 66; http://dx.doi.org/10.4161/cbt.6.7.4320; PMID: 17568187
   PubMed Web of Science ®Google Scholar
• Sasaki Y, Negishi H, Idogawa M, Yokota I, Koyama R, Kusano M, et al. p53 negatively regulates the hepatoma growth factor HDGF. Cancer Res 2011; 71:7038 - 47; http://dx.doi.org/10.1158/0008-5472.CAN-11-1053; PMID: 22006999
   PubMed Web of Science ®Google Scholar
• Miller LD, Smeds J, George J, Vega VB, Vergara L, Ploner A, et al. An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival. Proc Natl Acad Sci U S A 2005; 102:13550 - 5; http://dx.doi.org/10.1073/pnas.0506230102; PMID: 16141321
   PubMed Web of Science ®Google Scholar