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Clinical Study

Clinical usefulness of human epidermal growth factor receptor-2 extracellular domain as a biomarker for monitoring cancer status and predicting the therapeutic efficacy in breast cancer

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Pages 20-28 | Received 10 Jun 2012, Accepted 22 Oct 2012, Published online: 31 Oct 2012

References

  • Cheung KL, Graves CR, Robertson JF. Tumour marker measurements in the diagnosis and monitoring of breast cancer. Cancer Treat Rev 2000; 26:91 - 102; http://dx.doi.org/10.1053/ctrv.1999.0151; PMID: 10772967
  • Bast RC Jr., Ravdin P, Hayes DF, Bates S, Fritsche H Jr., Jessup JM, et al. American Society of Clinical Oncology Tumor Makers Expert Panel: 2000 update of recommendations for the use of tumor makers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2001; 19:1865 - 78; PMID: 11251019
  • Molina R, Jo J, Filella X, Zanon G, Pahisa J, Mu noz M, et al. c-erbB-2 oncoprotein, CEA, and CA 15.3 in patients with breast cancer: prognostic value. Breast Cancer Res Treat 1998; 51:109 - 19; http://dx.doi.org/10.1023/A:1005734429304; PMID: 9879773
  • Berry DA, Cirrincione C, Henderson IC, Citron ML, Budman DR, Goldstein LJ, et al. Estrogen-receptor status and outcomes of modern chemotherapy for patients with node-positive breast cancer. JAMA 2006; 295:1658 - 67; http://dx.doi.org/10.1001/jama.295.14.1658; PMID: 16609087
  • Pritchard KI, Shepherd LE, O’Malley FP, Andrulis IL, Tu D, Bramwell VH, et al, National Cancer Institute of Canada Clinical Trials Group. HER2 and responsiveness of breast cancer to adjuvant chemotherapy. N Engl J Med 2006; 354:2103 - 11; http://dx.doi.org/10.1056/NEJMoa054504; PMID: 16707747
  • Penault-Llorca F, André F, Sagan C, Lacroix-Triki M, Denoux Y, Verriele V, et al. Ki67 expression and docetaxel efficacy in patients with estrogen receptor-positive breast cancer. J Clin Oncol 2009; 27:2809 - 15; http://dx.doi.org/10.1200/JCO.2008.18.2808; PMID: 19380452
  • Akiyama T, Sudo C, Ogawara H, Toyoshima K, Yamamoto T. The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activity. Science 1986; 232:1644 - 6; http://dx.doi.org/10.1126/science.3012781; PMID: 3012781
  • Hynes NE, Stern DF. The biology of erbB-2/neu/HER-2 and its role in cancer. Biochim Biophys Acta 1994; 1198:165 - 84; PMID: 7819273
  • Riese DJ 2nd, Stern DF. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 1998; 20:41 - 8; http://dx.doi.org/10.1002/(SICI)1521-1878(199801)20:1<41::AID-BIES7>3.0.CO;2-V; PMID: 9504046
  • Yarden Y. The EGFR family and its ligands in human cancer: signaling mechanisms and therapeutic opportunities. Eur J Cancer 2001; 37:Suppl 4 3 - 8; http://dx.doi.org/10.1016/S0959-8049(01)00230-1; PMID: 11342194
  • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235:177 - 82; http://dx.doi.org/10.1126/science.3798106; PMID: 3798106
  • Sjögren S, Inganäs M, Lindgren A, Holmberg L, Bergh J. Prognostic and predictive value of c-erbB-2 overexpression in primary breast cancer, alone and in combination with other prognostic markers. J Clin Oncol 1998; 16:462 - 9; PMID: 9469329
  • Gabos Z, Sinha R, Hanson J, Chauhan N, Hugh J, Mackey JR, et al. Prognostic significance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer. J Clin Oncol 2006; 24:5658 - 63; http://dx.doi.org/10.1200/JCO.2006.07.0250; PMID: 17102066
  • Vogel CL, Cobleigh MA, Tripathy D, Gutheil JC, Harris LN, Fehrenbacher L, et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002; 20:719 - 26; http://dx.doi.org/10.1200/JCO.20.3.719; PMID: 11821453
  • Roche PC, Ingle JN. Increased HER2 with U.S. Food and Drug Administration-approved antibody. J Clin Oncol 1999; 17:434; PMID: 10458264
  • Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344:783 - 92; http://dx.doi.org/10.1056/NEJM200103153441101; PMID: 11248153
  • Pauletti G, Dandekar S, Rong H, Ramos L, Peng H, Seshadri R, et al. Assessment of methods for tissue-based detection of the HER-2/neu alteration in human breast cancer: a direct comparison of fluorescence in situ hybridization and immunohistochemistry. J Clin Oncol 2000; 18:3651 - 64; PMID: 11054438
  • Press MF, Hung G, Godolphin W, Slamon DJ. Sensitivity of HER-2/neu antibodies in archival tissue samples: potential source of error in immunohistochemical studies of oncogene expression. Cancer Res 1994; 54:2771 - 7; PMID: 7909495
  • Zabrecky JR, Lam T, McKenzie SJ, Carney W. The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells, SK-BR-3. J Biol Chem 1991; 266:1716 - 20; PMID: 1671042
  • Leitzel K, Teramoto Y, Sampson E, Mauceri J, Langton BC, Demers L, et al. Elevated soluble c-erbB-2 antigen levels in the serum and effusions of a proportion of breast cancer patients. J Clin Oncol 1992; 10:1436 - 43; PMID: 1355522
  • Lüftner D, Cheli C, Mickelson K, Sampson E, Possinger K. ADVIA Centaur HER-2/neu shows value in monitoring patients with metastatic breast cancer. Int J Biol Markers 2004; 19:175 - 82; PMID: 15503818
  • Kuroda N, Kontani K, Kajikawa T, Taminato T. Study of the measurement of serum extracellular domain of HER-2/neu protein with CLIA method. Rinsho Byori 2010; 58:541 - 52; PMID: 20662264
  • Carney WP, Neumann R, Lipton A, Leitzel K, Ali S, Price CP. Potential clinical utility of serum HER-2/neu oncoprotein concentrations in patients with breast cancer. Clin Chem 2003; 49:1579 - 98; http://dx.doi.org/10.1373/49.10.1579; PMID: 14500583
  • Carney WP. The Emerging Role of monitoring serum HER-2/neu oncoprotein levels in women with metastatic breast cancer. Lab Med 2003; 34:58 - 64; http://dx.doi.org/10.1309/TY6M-DWB0-G2BU-6D5F
  • Sturgeon CM, Duffy MJ, Stenman UH, Lilja H, Brünner N, Chan DW, et al, National Academy of Clinical Biochemistry. National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers. Clin Chem 2008; 54:e11 - 79; http://dx.doi.org/10.1373/clinchem.2008.105601; PMID: 19042984
  • Hayes DF, Yamauchi H, Broadwater G, Cirrincione CT, Rodrigue SP, Berry DA, et al, Cancer and Leukemia Group B. Circulating HER-2/erbB-2/c-neu (HER-2) extracellular domain as a prognostic factor in patients with metastatic breast cancer: Cancer and Leukemia Group B Study 8662. Clin Cancer Res 2001; 7:2703 - 11; PMID: 11555582
  • Lipton A, Ali SM, Leitzel K, Demers L, Chinchilli V, Engle L, et al. Elevated serum Her-2/neu level predicts decreased response to hormone therapy in metastatic breast cancer. J Clin Oncol 2002; 20:1467 - 72; http://dx.doi.org/10.1200/JCO.20.6.1467; PMID: 11896093
  • Colomer R, Llombart-Cussac A, Lloveras B, Ramos M, Mayordomo JI, Fernández R, et al. High circulating HER2 extracellular domain levels correlate with reduced efficacy of an aromatase inhibitor in hormone receptor-positive metastatic breast cancer: a confirmatory prospective study. Cancer 2007; 110:2178 - 85; http://dx.doi.org/10.1002/cncr.23043; PMID: 17926331
  • Colomer R, Montero S, Lluch A, Ojeda B, Barnadas A, Casado A, et al. Circulating HER2 extracellular domain and resistance to chemotherapy in advanced breast cancer. Clin Cancer Res 2000; 6:2356 - 62; PMID: 10873087
  • Köstler WJ, Schwab B, Singer CF, Neumann R, Rücklinger E, Brodowicz T, et al. Monitoring of serum Her-2/neu predicts response and progression-free survival to trastuzumab-based treatment in patients with metastatic breast cancer. Clin Cancer Res 2004; 10:1618 - 24; http://dx.doi.org/10.1158/1078-0432.CCR-0385-3; PMID: 15014012
  • Ali SM, Carney WP, Esteva FJ, Fornier M, Harris L, Köstler WJ, et al, Serum HER-2/neu Study Group. Serum HER-2/neu and relative resistance to trastuzumab-based therapy in patients with metastatic breast cancer. Cancer 2008; 113:1294 - 301; http://dx.doi.org/10.1002/cncr.23689; PMID: 18661530
  • Molina R, Jo J, Filella X, Bruix J, Castells A, Hague M, et al. Serum levels of C-erbB-2 (HER-2/neu) in patients with malignant and non-malignant diseases. Tumour Biol 1997; 18:188 - 96; http://dx.doi.org/10.1159/000218029; PMID: 9143415
  • Kashiwaba M, Hayakawa Y, Takiyama I, Inaba R, Itoh N, Saito K. Nihon Gekagakkaizasshi 2005; 106:587
  • Smith I, Procter M, Gelber RD, Guillaume S, Feyereislova A, Dowsett M, et al, HERA study team. 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial. Lancet 2007; 369:29 - 36; http://dx.doi.org/10.1016/S0140-6736(07)60028-2; PMID: 17208639
  • Buzdar AU, Valero V, Ibrahim NK, Francis D, Broglio KR, Theriault RL, et al. Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: an update of the initial randomized study population and data of additional patients treated with the same regimen. Clin Cancer Res 2007; 13:228 - 33; http://dx.doi.org/10.1158/1078-0432.CCR-06-1345; PMID: 17200359
  • Valero V, Forbes J, Pegram MD, Pienkowski T, Eiermann W, von Minckwitz G, et al. Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): two highly active therapeutic regimens. J Clin Oncol 2011; 29:149 - 56; http://dx.doi.org/10.1200/JCO.2010.28.6450; PMID: 21115860
  • Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344:783 - 92; http://dx.doi.org/10.1056/NEJM200103153441101; PMID: 11248153
  • Scaltriti M, Rojo F, Ocaña A, Anido J, Guzman M, Cortes J, et al. Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer. J Natl Cancer Inst 2007; 99:628 - 38; http://dx.doi.org/10.1093/jnci/djk134; PMID: 17440164
  • Molina MA, Codony-Servat J, Albanell J, Rojo F, Arribas J, Baselga J. Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells. Cancer Res 2001; 61:4744 - 9; PMID: 11406546
  • Leary AF, Hanna WM, van de Vijver MJ, Penault-Llorca F, Rüschoff J, Osamura RY, et al. Value and limitations of measuring HER-2 extracellular domain in the serum of breast cancer patients. J Clin Oncol 2009; 27:1694 - 705; http://dx.doi.org/10.1200/JCO.2008.17.3989; PMID: 19255333

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