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Review

Adult primary pulmonary primitive neuroectodermal tumor

Molecular features and translational opportunities

, , , &
Pages 75-80 | Received 16 Aug 2012, Accepted 22 Oct 2012, Published online: 31 Oct 2012

References

  • Stout AP. A tumor of the ulnar nerve. Proc NY Pathol Soc 1918; 18:2-12.
  • Ewing J. Classics in oncology. Diffuse endothelioma of bone. James Ewing. Proceedings of the New York Pathological Society, 1921. CA Cancer J Clin 1972; 22:95 - 8; http://dx.doi.org/10.3322/canjclin.22.2.95; PMID: 4622125
  • Askin FB, Rosai J, Sibley RK, Dehner LP, McAlister WH. Malignant small cell tumor of the thoracopulmonary region in childhood: a distinctive clinicopathologic entity of uncertain histogenesis. Cancer 1979; 43:2438 - 51; http://dx.doi.org/10.1002/1097-0142(197906)43:6<2438::AID-CNCR2820430640>3.0.CO;2-9; PMID: 222426
  • Scurr M, Judson I. How to treat the Ewing’s family of sarcomas in adult patients. Oncologist 2006; 11:65 - 72; http://dx.doi.org/10.1634/theoncologist.11-1-65; PMID: 16401715
  • Kumar V, Fausto N, Abbas A. Robbins & Cotran Pathologic Basis of Disease Seventh Edition, 2004.
  • Zhang WD, Xie CM, Mo YX, Li JY. [CT and MRI features of peripheral primitive neuroectodermal tumor]. Ai Zheng 2007; 26:643 - 6; PMID: 17562273
  • de Alava E, Gerald WL. Molecular biology of the Ewing’s sarcoma/primitive neuroectodermal tumor family. J Clin Oncol 2000; 18:204 - 13; PMID: 10623711
  • Kolb EA, Kushner BH, Gorlick R, Laverdiere C, Healey JH, LaQuaglia MP, et al. Long-term event-free survival after intensive chemotherapy for Ewing’s family of tumors in children and young adults. J Clin Oncol 2003; 21:3423 - 30; http://dx.doi.org/10.1200/JCO.2003.10.033; PMID: 12972518
  • Jürgens H, Bier V, Harms D, Beck J, Brandeis W, Etspüler G, et al. Malignant peripheral neuroectodermal tumors. A retrospective analysis of 42 patients. Cancer 1988; 61:349 - 57; http://dx.doi.org/10.1002/1097-0142(19880115)61:2<349::AID-CNCR2820610226>3.0.CO;2-0; PMID: 3334970
  • Riggi N, Stamenkovic I. The Biology of Ewing sarcoma. Cancer Lett 2007; 254:1 - 10; http://dx.doi.org/10.1016/j.canlet.2006.12.009; PMID: 17250957
  • Ohno T, Ouchida M, Lee L, Gatalica Z, Rao VN, Reddy ES. The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains. Oncogene 1994; 9:3087 - 97; PMID: 8084618
  • Plougastel B, Zucman J, Peter M, Thomas G, Delattre O. Genomic structure of the EWS gene and its relationship to EWSR1, a site of tumor-associated chromosome translocation. Genomics 1993; 18:609 - 15; http://dx.doi.org/10.1016/S0888-7543(05)80363-5; PMID: 8307570
  • Tan AY, Manley JL. The TET family of proteins: functions and roles in disease. J Mol Cell Biol 2009; 1:82 - 92; http://dx.doi.org/10.1093/jmcb/mjp025; PMID: 19783543
  • Bertolotti A, Lutz Y, Heard DJ, Chambon P, Tora L. hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II. EMBO J 1996; 15:5022 - 31; PMID: 8890175
  • Arvand A, Denny CT. Biology of EWS/ETS fusions in Ewing’s family tumors. Oncogene 2001; 20:5747 - 54; http://dx.doi.org/10.1038/sj.onc.1204598; PMID: 11607824
  • Petermann R, Mossier BM, Aryee DN, Khazak V, Golemis EA, Kovar H. Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II. Oncogene 1998; 17:603 - 10; http://dx.doi.org/10.1038/sj.onc.1201964; PMID: 9704926
  • Prasad DDK, Rao VN, Reddy ES, Reddy P. Structure and expression of human Fli-1 gene. Cancer Res 1992; 52:5833 - 7; PMID: 1394211
  • Ben-David Y, Giddens EB, Letwin K, Bernstein A. Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Genes Dev 1991; 5:908 - 18; http://dx.doi.org/10.1101/gad.5.6.908; PMID: 2044959
  • Blair DG, Athanasiou M. Ets and retroviruses - transduction and activation of members of the Ets oncogene family in viral oncogenesis. Oncogene 2000; 19:6472 - 81; http://dx.doi.org/10.1038/sj.onc.1204046; PMID: 11175363
  • Rao VN, Ohno T, Prasad DD, Bhattacharya G, Reddy ES. Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein. Oncogene 1993; 8:2167 - 73; PMID: 8336942
  • Truong AH, Ben-David Y. The role of Fli-1 in normal cell function and malignant transformation. Oncogene 2000; 19:6482 - 9; http://dx.doi.org/10.1038/sj.onc.1204042; PMID: 11175364
  • Pereira R, Quang CT, Lesault I, Dolznig H, Beug H, Ghysdael J. FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts. Oncogene 1999; 18:1597 - 608; http://dx.doi.org/10.1038/sj.onc.1202534; PMID: 10102630
  • Turc-Carel C, Aurias A, Mugneret F, Lizard S, Sidaner I, Volk C, et al. Chromosomes in Ewing’s sarcoma. I. An evaluation of 85 cases of remarkable consistency of t(11;22)(q24;q12). Cancer Genet Cytogenet 1988; 32:229 - 38; http://dx.doi.org/10.1016/0165-4608(88)90285-3; PMID: 3163261
  • Delattre O, Zucman J, Melot T, Garau XS, Zucker JM, Lenoir GM, et al. The Ewing family of tumors--a subgroup of small-round-cell tumors defined by specific chimeric transcripts. N Engl J Med 1994; 331:294 - 9; http://dx.doi.org/10.1056/NEJM199408043310503; PMID: 8022439
  • Maire G, Brown CW, Bayani J, Pereira C, Gravel DH, Bell JC, et al. Complex rearrangement of chromosomes 19, 21, and 22 in Ewing sarcoma involving a novel reciprocal inversion-insertion mechanism of EWS-ERG fusion gene formation: a case analysis and literature review. Cancer Genet Cytogenet 2008; 181:81 - 92; http://dx.doi.org/10.1016/j.cancergencyto.2007.11.002; PMID: 18295659
  • Jedlicka P. Ewing Sarcoma, an enigmatic malignancy of likely progenitor cell origin, driven by transcription factor oncogenic fusions. Int J Clin Exp Pathol 2010; 3:338 - 47; PMID: 20490326
  • Downing JR, Head DR, Parham DM, Douglass EC, Hulshof MG, Link MP, et al. Detection of the (11;22)(q24;q12) translocation of Ewing’s sarcoma and peripheral neuroectodermal tumor by reverse transcription polymerase chain reaction. Am J Pathol 1993; 143:1294 - 300; PMID: 8238248
  • Ordonez JL, Osuna D, Herrero D. Enrique de Alava, Madoz-Gurpide J. Advances in Ewing’s Sarcoma Research: Where are you now and what lies ahead?. Cancer Res 2009; 69:7140 - 50; http://dx.doi.org/10.1158/0008-5472.CAN-08-4041; PMID: 19738075
  • Petermann R, Mossier BM, Aryee DN, Khazak V, Golemis EA, Kovar H. Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II. Oncogene 1998; 17:603 - 10; http://dx.doi.org/10.1038/sj.onc.1201964; PMID: 9704926
  • May WA, Gishizky ML, Lessnick SL, Lunsford LB, Lewis BC, Delattre O, et al. Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proc Natl Acad Sci USA 1993; 90:5752 - 6; http://dx.doi.org/10.1073/pnas.90.12.5752; PMID: 8516324
  • Ladanyi M. The emerging molecular genetics of sarcoma translocations. Diagn Mol Pathol 1995; 4:162 - 73; http://dx.doi.org/10.1097/00019606-199509000-00003; PMID: 7493135
  • Lin PP, Brody RI, Hamelin AC, Bradner JE, Healey JH, Ladanyi M. Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing’s sarcoma. Cancer Res 1999; 59:1428 - 32; PMID: 10197607
  • Hattinger CM, Rumpler S, Strehl S, Ambros IM, Zoubek A, Pötschger U, et al. Prognostic impact of deletions at 1p36 and numerical aberrations in Ewing tumors. Genes Chromosomes Cancer 1999; 24:243 - 54; http://dx.doi.org/10.1002/(SICI)1098-2264(199903)24:3<243::AID-GCC10>3.0.CO;2-A; PMID: 10451705
  • Uren A, Toretsky JA. Ewing’s sarcoma oncoprotein EWS-FLI1: the perfect target without a therapeutic agent. Future Oncol 2005; 1:521 - 8; http://dx.doi.org/10.2217/14796694.1.4.521; PMID: 16556028
  • Mateo-Lozano S, Gokhale PC, Soldatenkov VA, Dritschilo A, Tirado OM, Notario V. Combined transcriptional and translational targeting of EWS/FLI-1 in Ewing’s sarcoma. Clin Cancer Res 2006; 12:6781 - 90; http://dx.doi.org/10.1158/1078-0432.CCR-06-0609; PMID: 17121899
  • Takigami I, Ohno T, Kitade Y, Hara A, Nagano A, Kawai G, et al. Synthetic siRNA targeting the breakpoint of EWS/Fli-1 inhibits growth of Ewing sarcoma xenografts in a mouse model. Int J Cancer 2011; 128:216 - 26; http://dx.doi.org/10.1002/ijc.25564; PMID: 20648560

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