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Research Paper

Oncogenic but non-essential role of N-myc downstream regulated gene 1 in the progression of esophageal squamous cell carcinoma

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Pages 164-174 | Received 24 Aug 2012, Accepted 18 Nov 2012, Published online: 28 Nov 2012

Reference List

  • Lam AK. Molecular biology of esophageal squamous cell carcinoma. Crit Rev Oncol Hematol 2000; 33:71 - 90; http://dx.doi.org/10.1016/S1040-8428(99)00054-2; PMID: 10737369
  • Sohda M, Mochida Y, Kato H, Miyazaki T, Nakajima M, Fukuchi M, et al. Overexpression of Cap43 is associated with malignant status of esophageal cancer. Anticancer Res 2009; 29:965 - 70; PMID: 19414333
  • Kovacevic Z, Richardson DR. The metastasis suppressor, Ndrg-1: a new ally in the fight against cancer. Carcinogenesis 2006; 27:2355 - 66; http://dx.doi.org/10.1093/carcin/bgl146; PMID: 16920733
  • Stein S, Thomas EK, Herzog B, Westfall MD, Rocheleau JV, Jackson RS 2nd, et al. NDRG1 is necessary for p53-dependent apoptosis. J Biol Chem 2004; 279:48930 - 40; http://dx.doi.org/10.1074/jbc.M400386200; PMID: 15377670
  • Cangul H. Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers. BMC Genet 2004; 5:27; http://dx.doi.org/10.1186/1471-2156-5-27; PMID: 15341671
  • Le NT, Richardson DR. Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation. Blood 2004; 104:2967 - 75; http://dx.doi.org/10.1182/blood-2004-05-1866; PMID: 15251988
  • Salnikow K, Kluz T, Costa M, Piquemal D, Demidenko ZN, Xie K, et al. The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia. Mol Cell Biol 2002; 22:1734 - 41; http://dx.doi.org/10.1128/MCB.22.6.1734-1741.2002; PMID: 11865053
  • Zhang P, Tchou-Wong KM, Costa M. Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter. Cancer Res 2007; 67:9125 - 33; http://dx.doi.org/10.1158/0008-5472.CAN-07-1525; PMID: 17909017
  • Bandyopadhyay S, Pai SK, Hirota S, Hosobe S, Tsukada T, Miura K, et al. PTEN up-regulates the tumor metastasis suppressor gene Drg-1 in prostate and breast cancer. Cancer Res 2004; 64:7655 - 60; http://dx.doi.org/10.1158/0008-5472.CAN-04-1623; PMID: 15520163
  • Li J, Kretzner L. The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc. Mol Cell Biochem 2003; 250:91 - 105; http://dx.doi.org/10.1023/A:1024918328162; PMID: 12962147
  • Zhang J, Chen S, Zhang W, Zhang J, Liu X, Shi H, et al. Human differentiation-related gene NDRG1 is a Myc downstream-regulated gene that is repressed by Myc on the core promoter region. Gene 2008; 417:5 - 12; http://dx.doi.org/10.1016/j.gene.2008.03.002; PMID: 18455888
  • Masuda K, Ono M, Okamoto M, Morikawa W, Otsubo M, Migita T, et al. Downregulation of Cap43 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells. Int J Cancer 2003; 105:803 - 10; http://dx.doi.org/10.1002/ijc.11152; PMID: 12767066
  • Guan RJ, Ford HL, Fu Y, Li Y, Shaw LM, Pardee AB. Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer. Cancer Res 2000; 60:749 - 55; PMID: 10676663
  • Bandyopadhyay S, Pai SK, Hirota S, Hosobe S, Takano Y, Saito K, et al. Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression. Oncogene 2004; 23:5675 - 81; http://dx.doi.org/10.1038/sj.onc.1207734; PMID: 15184886
  • Bandyopadhyay S, Pai SK, Gross SC, Hirota S, Hosobe S, Miura K, et al. The Drg-1 gene suppresses tumor metastasis in prostate cancer. Cancer Res 2003; 63:1731 - 6; PMID: 12702552
  • Maruyama Y, Ono M, Kawahara A, Yokoyama T, Basaki Y, Kage M, et al. Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis. Cancer Res 2006; 66:6233 - 42; http://dx.doi.org/10.1158/0008-5472.CAN-06-0183; PMID: 16778198
  • Dang C, Gottschling M, Manning K, O’Currain E, Schneider S, Sterry W, et al. Identification of dysregulated genes in cutaneous squamous cell carcinoma. Oncol Rep 2006; 16:513 - 9; PMID: 16865251
  • Gómez-Casero E, Navarro M, Rodríguez-Puebla ML, Larcher F, Paramio JM, Conti CJ, et al. Regulation of the differentiation-related gene Drg-1 during mouse skin carcinogenesis. Mol Carcinog 2001; 32:100 - 9; http://dx.doi.org/10.1002/mc.1069; PMID: 11746822
  • Chang JT, Wang HM, Chang KW, Chen WH, Wen MC, Hsu YM, et al. Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): overexpression of NPM, CDK1 and NDRG1 and underexpression of CHES1. Int J Cancer 2005; 114:942 - 9; http://dx.doi.org/10.1002/ijc.20663; PMID: 15645429
  • Nishio S, Ushijima K, Tsuda N, Takemoto S, Kawano K, Yamaguchi T, et al. Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma. Cancer Lett 2008; 264:36 - 43; http://dx.doi.org/10.1016/j.canlet.2008.01.020; PMID: 18281151
  • Nishie A, Masuda K, Otsubo M, Migita T, Tsuneyoshi M, Kohno K, et al. High expression of the Cap43 gene in infiltrating macrophages of human renal cell carcinomas. Clin Cancer Res 2001; 7:2145 - 51; PMID: 11448934
  • Wang Z, Wang F, Wang WQ, Gao Q, Wei WL, Yang Y, et al. Correlation of N-myc downstream-regulated gene 1 overexpression with progressive growth of colorectal neoplasm. World J Gastroenterol 2004; 10:550 - 4; PMID: 14966915
  • Sibold S, Roh V, Keogh A, Studer P, Tiffon C, Angst E, et al. Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma. FEBS Lett 2007; 581:989 - 94; http://dx.doi.org/10.1016/j.febslet.2007.01.080; PMID: 17316623
  • Chua MS, Sun H, Cheung ST, Mason V, Higgins J, Ross DT, et al. Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma. Mod Pathol 2007; 20:76 - 83; http://dx.doi.org/10.1038/modpathol.3800711; PMID: 17170744
  • Yan X, Chua MS, Sun H, So S. N-Myc down-regulated gene 1 mediates proliferation, invasion, and apoptosis of hepatocellular carcinoma cells. Cancer Lett 2008; 262:133 - 42; http://dx.doi.org/10.1016/j.canlet.2007.12.010; PMID: 18207320
  • Motwani M, Sirotnak FM, She Y, Commes T, Schwartz GK. Drg1, a novel target for modulating sensitivity to CPT-11 in colon cancer cells. Cancer Res 2002; 62:3950 - 5; PMID: 12124325
  • Shah MA, Kemeny N, Hummer A, Drobnjak M, Motwani M, Cordon-Cardo C, et al. Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes. Clin Cancer Res 2005; 11:3296 - 302; http://dx.doi.org/10.1158/1078-0432.CCR-04-2417; PMID: 15867226
  • Chen B, Nelson DM, Sadovsky Y. N-myc down-regulated gene 1 modulates the response of term human trophoblasts to hypoxic injury. J Biol Chem 2006; 281:2764 - 72; http://dx.doi.org/10.1074/jbc.M507330200; PMID: 16314423
  • Shimada Y, Imamura M, Wagata T, Yamaguchi N, Tobe T. Characterization of 21 newly established esophageal cancer cell lines. Cancer 1992; 69:277 - 84; http://dx.doi.org/10.1002/1097-0142(19920115)69:2<277::AID-CNCR2820690202>3.0.CO;2-C; PMID: 1728357
  • Wiznerowicz M, Trono D. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J Virol 2003; 77:8957 - 61; http://dx.doi.org/10.1128/JVI.77.16.8957-8951.2003; PMID: 12885912
  • Tiscornia G, Singer O, Verma IM. Production and purification of lentiviral vectors. Nat Protoc 2006; 1:241 - 5; http://dx.doi.org/10.1038/nprot.2006.37; PMID: 17406239
  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25:402 - 8; http://dx.doi.org/10.1006/meth.2001.1262; PMID: 11846609
  • Nagata J, Kijima H, Hatanaka H, Tokunaga T, Kamochi J, Abe Y, et al. Angiopoietin-1 and vascular endothelial growth factor expression in human esophageal cancer. Int J Mol Med 2002; 10:423 - 6; PMID: 12239588
  • Kantak SS, Kramer RH. E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells. J Biol Chem 1998; 273:16953 - 61; http://dx.doi.org/10.1074/jbc.273.27.16953; PMID: 9642258
  • Liang CC, Park AY, Guan JL. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2007; 2:329 - 33; http://dx.doi.org/10.1038/nprot.2007.30; PMID: 17406593
  • Leaner VD, Donninger H, Ellis CA, Clark GJ, Birrer MJ. p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells. Mol Cell Biol 2005; 25:3324 - 37; http://dx.doi.org/10.1128/MCB.25.8.3324-3337.2005; PMID: 15798216
  • Wang B, Khachigian LM, Esau L, Birrer MJ, Zhao X, Parker MI, et al. A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer. Mol Cancer Res 2009; 7:755 - 64; http://dx.doi.org/10.1158/1541-7786.MCR-08-0472; PMID: 19435811
  • Loges S, Clausen H, Reichelt U, Bubenheim M, Erbersdobler A, Schurr P, et al. Determination of microvessel density by quantitative real-time PCR in esophageal cancer: correlation with histologic methods, angiogenic growth factor expression, and lymph node metastasis. Clin Cancer Res 2007; 13:76 - 80; http://dx.doi.org/10.1158/1078-0432.CCR-06-1324; PMID: 17200341
  • Matsumoto S, Yamada Y, Narikiyo M, Ueno M, Tamaki H, Miki K, et al. Prognostic significance of platelet-derived growth factor-BB expression in human esophageal squamous cell carcinomas. Anticancer Res 2007; 27:4B 2409 - 14; PMID: 17695532
  • Krzystek-Korpacka M, Matusiewicz M, Diakowska D, Grabowski K, Blachut K, Konieczny D, et al. Elevation of circulating interleukin-8 is related to lymph node and distant metastases in esophageal squamous cell carcinomas--implication for clinical evaluation of cancer patient. Cytokine 2008; 41:232 - 9; http://dx.doi.org/10.1016/j.cyto.2007.11.011; PMID: 18182303
  • Strieter RM, Belperio JA, Phillips RJ, Keane MP. CXC chemokines in angiogenesis of cancer. Semin Cancer Biol 2004; 14:195 - 200; http://dx.doi.org/10.1016/j.semcancer.2003.10.006; PMID: 15246055
  • Oka M, Yamamoto K, Takahashi M, Hakozaki M, Abe T, Iizuka N, et al. Relationship between serum levels of interleukin 6, various disease parameters and malnutrition in patients with esophageal squamous cell carcinoma. Cancer Res 1996; 56:2776 - 80; PMID: 8665513
  • Okuda T, Higashi Y, Kokame K, Tanaka C, Kondoh H, Miyata T. Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves. Mol Cell Biol 2004; 24:3949 - 56; http://dx.doi.org/10.1128/MCB.24.9.3949-3956.2004; PMID: 15082788
  • Okuda T, Kokame K, Miyata T. Differential expression patterns of NDRG family proteins in the central nervous system. J Histochem Cytochem 2008; 56:175 - 82; http://dx.doi.org/10.1369/jhc.7A7323.2007; PMID: 17998568
  • Haustermans K, Hofland I, Van de Pavert L, Geboes K, Varia M, Raleigh J, et al. Diffusion limited hypoxia estimated by vascular image analysis: comparison with pimonidazole staining in human tumors. Radiother Oncol 2000; 55:325 - 33; http://dx.doi.org/10.1016/S0167-8140(00)00206-1; PMID: 10869747
  • Harris AL. Hypoxia--a key regulatory factor in tumour growth. Nat Rev Cancer 2002; 2:38 - 47; http://dx.doi.org/10.1038/nrc704; PMID: 11902584
  • Li B, Li YY, Tsao SW, Cheung AL. Targeting NF-kappaB signaling pathway suppresses tumor growth, angiogenesis, and metastasis of human esophageal cancer. Mol Cancer Ther 2009; 8:2635 - 44; http://dx.doi.org/10.1158/1535-7163.MCT-09-0162; PMID: 19723887
  • Izzo JG, Wu X, Wu TT, Huang P, Lee JS, Liao Z, et al. Therapy-induced expression of NF-kappaB portends poor prognosis in patients with localized esophageal cancer undergoing preoperative chemoradiation. Dis Esophagus 2009; 22:127 - 32; http://dx.doi.org/10.1111/j.1442-2050.2008.00884.x; PMID: 19021681