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Brief Communication

A molecular case report

Functional assay of tyrosine kinase inhibitors in cells from a patient’s primary renal cell carcinoma

, , , , , , & show all
Pages 95-99 | Received 09 Nov 2012, Accepted 18 Nov 2012, Published online: 28 Nov 2012

References

  • Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344:1031 - 7; http://dx.doi.org/10.1056/NEJM200104053441401; PMID: 11287972
  • Tyner JW, Erickson H, Deininger MW, Willis SG, Eide CA, Levine RL, et al. High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients. Blood 2009; 113:1749 - 55; http://dx.doi.org/10.1182/blood-2008-04-152157; PMID: 19075190
  • Tyner JW, Fletcher LB, Wang EQ, Yang WF, Rutenberg-Schoenberg ML, Beadling C, et al. MET receptor sequence variants R970C and T992I lack transforming capacity. Cancer Res 2010; 70:6233 - 7; http://dx.doi.org/10.1158/0008-5472.CAN-10-0429; PMID: 20670955
  • Tyner JW, Yang WF, Bankhead A, Fan G, Fletcher LB, Bryant J, et al. Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening. Cancer Res 2012; http://dx.doi.org/10.1158/0008-5472.CAN-12-1906; PMID: 23087056
  • Suwaki N, Vanhecke E, Atkins KM, Graf M, Swabey K, Huang P, et al. A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma. Sci Transl Med 2011; 3:85ra47; http://dx.doi.org/10.1126/scitranslmed.3002004; PMID: 21632985
  • Sternberg CN, Davis ID, Mardiak J, Szczylik C, Lee E, Wagstaff J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010; 28:1061 - 8; http://dx.doi.org/10.1200/JCO.2009.23.9764; PMID: 20100962
  • Garnett MJ, Edelman EJ, Heidorn SJ, Greenman CD, Dastur A, Lau KW, et al. Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature 2012; 483:570 - 5; http://dx.doi.org/10.1038/nature11005; PMID: 22460902
  • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646 - 74; http://dx.doi.org/10.1016/j.cell.2011.02.013; PMID: 21376230
  • Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 2012; 21:309 - 22; http://dx.doi.org/10.1016/j.ccr.2012.02.022; PMID: 22439926
  • Jaganathan S, Yue P, Paladino DC, Bogdanovic J, Huo Q, Turkson J. A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells. PLoS One 2011; 6:e19605; http://dx.doi.org/10.1371/journal.pone.0019605; PMID: 21573184
  • Dancey JE. Epidermal growth factor receptor and epidermal growth factor receptor therapies in renal cell carcinoma: do we need a better mouse trap?. J Clin Oncol 2004; 22:2975 - 7; http://dx.doi.org/10.1200/JCO.2004.04.934; PMID: 15210735
  • An J, Rettig MB. Epidermal growth factor receptor inhibition sensitizes renal cell carcinoma cells to the cytotoxic effects of bortezomib. Mol Cancer Ther 2007; 6:61 - 9; http://dx.doi.org/10.1158/1535-7163.MCT-06-0255; PMID: 17237266
  • Akbulut T, Regner KR, Roman RJ, Avner ED, Falck JR, Park F. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism. Am J Physiol Renal Physiol 2009; 297:F662 - 70; http://dx.doi.org/10.1152/ajprenal.00146.2009; PMID: 19570883
  • Suzuki T, Fujii A, Ochi H, Nakamura H. Ubiquitination and downregulation of ErbB2 and estrogen receptor-alpha by kinase inhibitor MP-412 in human breast cancer cells. J Cell Biochem 2011; 112:2279 - 86; http://dx.doi.org/10.1002/jcb.23147; PMID: 21503962
  • Kulesz-Martin MF, McLimans WF. Steady-state cultures of human skin. Exp Cell Biol 1982; 50:195 - 206; PMID: 6749572
  • Rheinwald JG, Jorgensen JL, Hahn WC, Terpstra AJ, O’Connell TM, Plummer KK. Mesosecrin: a secreted glycoprotein produced in abundance by human mesothelial, endothelial, and kidney epithelial cells in culture. J Cell Biol 1987; 104:263 - 75; http://dx.doi.org/10.1083/jcb.104.2.263; PMID: 3543023
  • Rheinwald JG, O’Connell TM. Intermediate filament proteins as distinguishing markers of cell type and differentiated state in cultured human urinary tract epithelia. Ann N Y Acad Sci 1985; 455:259 - 67; http://dx.doi.org/10.1111/j.1749-6632.1985.tb50416.x; PMID: 3866508
  • Casalone R, Granata Casalone P, Minelli E, Portentoso P, Righi R, Meroni E, et al. Significance of the clonal and sporadic chromosome abnormalities in non-neoplastic renal tissue. Hum Genet 1992; 90:71 - 8; http://dx.doi.org/10.1007/BF00210747; PMID: 1427791
  • van den Berg E, van der Hout AH, Oosterhuis JW, Störkel S, Dijkhuizen T, Dam A, et al. Cytogenetic analysis of epithelial renal-cell tumors: relationship with a new histopathological classification. Int J Cancer 1993; 55:223 - 7; http://dx.doi.org/10.1002/ijc.2910550210; PMID: 8370620