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Research Paper

Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma

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Pages 436-442 | Received 23 Oct 2013, Accepted 22 Dec 2013, Published online: 21 Jan 2014

References

  • Fanucchi M, Khuri FR. Chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck. Semin Oncol 2004; 31:809 - 15; http://dx.doi.org/10.1053/j.seminoncol.2004.09.014; PMID: 15599859
  • Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002; 2:48 - 58; http://dx.doi.org/10.1038/nrc706; PMID: 11902585
  • Colevas AD. Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 2006; 24:2644 - 52; http://dx.doi.org/10.1200/JCO.2005.05.3348; PMID: 16763278
  • Kamazawa S, Kigawa J, Minagawa Y, Itamochi H, Shimada M, Takahashi M, Sato S, Akeshima R, Terakawa N. Cellular efflux pump and interaction between cisplatin and paclitaxel in ovarian cancer cells. Oncology 2000; 59:329 - 35; http://dx.doi.org/10.1159/000012191; PMID: 11096346
  • Lagas JS, Vlaming ML, van Tellingen O, Wagenaar E, Jansen RS, Rosing H, Beijnen JH, Schinkel AH. Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics. Clin Cancer Res 2006; 12:6125 - 32; http://dx.doi.org/10.1158/1078-0432.CCR-06-1352; PMID: 17062689
  • Duan Z, Brakora KA, Seiden MV. Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells. Mol Cancer Ther 2004; 3:833 - 8; PMID: 15252144
  • Pratt S, Shepard RL, Kandasamy RA, Johnston PA, Perry W 3rd, Dantzig AH. The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites. Mol Cancer Ther 2005; 4:855 - 63; http://dx.doi.org/10.1158/1535-7163.MCT-04-0291; PMID: 15897250
  • Guminski AD, Balleine RL, Chiew YE, Webster LR, Tapner M, Farrell GC, Harnett PR, Defazio A. MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma. Gynecol Oncol 2006; 100:239 - 46; http://dx.doi.org/10.1016/j.ygyno.2005.08.046; PMID: 16213010
  • Weaver DA, Crawford EL, Warner KA, Elkhairi F, Khuder SA, Willey JC. ABCC5, ERCC2, XPA and XRCC1 transcript abundance levels correlate with cisplatin chemoresistance in non-small cell lung cancer cell lines. Mol Cancer 2005; 4:18; http://dx.doi.org/10.1186/1476-4598-4-18; PMID: 15882455
  • Song IS, Savaraj N, Siddik ZH, Liu P, Wei Y, Wu CJ, Kuo MT. Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells. Mol Cancer Ther 2004; 3:1543 - 9; PMID: 15634647
  • Nakayama K, Kanzaki A, Ogawa K, Miyazaki K, Neamati N, Takebayashi Y. Copper-transporting P-type adenosine triphophatase (ATP7B) as a cisplatin-based chemoresistance marker in ovarian carcinoma: comparative analysis with expression of MDR1, MRP, LRP and BCRP. Int J Cancer 2002; 101:488 - 95; http://dx.doi.org/10.1002/ijc.10608; PMID: 12216079
  • Theile D, Ketabi-Kiyanvash N, Herold-Mende C, Dyckhoff G, Efferth T, Bertholet V, Haefeli WE, Weiss J. Evaluation of drug transporters’ significance for multidrug resistance in head and neck squamous cell carcinoma. Head Neck 2011; 33:959 - 68; http://dx.doi.org/10.1002/hed.21559; PMID: 20737486
  • Scotto KW. Transcriptional regulation of ABC drug transporters. Oncogene 2003; 22:7496 - 511; http://dx.doi.org/10.1038/sj.onc.1206950; PMID: 14576854
  • Blumberg B, Sabbagh W Jr., Juguilon H, Bolado J Jr., van Meter CM, Ong ES, Evans RM. SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev 1998; 12:3195 - 205; http://dx.doi.org/10.1101/gad.12.20.3195; PMID: 9784494
  • Synold TW, Dussault I, Forman BM. The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med 2001; 7:584 - 90; http://dx.doi.org/10.1038/87912; PMID: 11329060
  • Beijnen JH, Schellens JH. Drug interactions in oncology. Lancet Oncol 2004; 5:489 - 96; http://dx.doi.org/10.1016/S1470-2045(04)01528-1; PMID: 15288238
  • Desai PB, Nallani SC, Sane RS, Moore LB, Goodwin BJ, Buckley DJ, Buckley AR. Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen. Drug Metab Dispos 2002; 30:608 - 12; http://dx.doi.org/10.1124/dmd.30.5.608; PMID: 11950795
  • Huang R, Murry DJ, Kolwankar D, Hall SD, Foster DR. Vincristine transcriptional regulation of efflux drug transporters in carcinoma cell lines. Biochem Pharmacol 2006; 71:1695 - 704; http://dx.doi.org/10.1016/j.bcp.2006.03.009; PMID: 16620787
  • Hille S, Rein DT, Riffelmann M, Neumann R, Sartorius J, Pfützner A, Kurbacher CM, Schöndorf T, Breidenbach M. Anticancer drugs induce mdr1 gene expression in recurrent ovarian cancer. Anticancer Drugs 2006; 17:1041 - 4; http://dx.doi.org/10.1097/01.cad.0000231480.07654.b5; PMID: 17001177
  • Schöndorf T, Neumann R, Benz C, Becker M, Riffelmann M, Göhring UJ, Sartorius J, von König CH, Breidenbach M, Valter MM, et al. Cisplatin, doxorubicin and paclitaxel induce mdr1 gene transcription in ovarian cancer cell lines. Recent Results Cancer Res 2003; 161:111 - 6; http://dx.doi.org/10.1007/978-3-642-19022-3_10; PMID: 12528803
  • Su GM, Davey MW, Davey RA. Induction of broad drug resistance in small cell lung cancer cells and its reversal by paclitaxel. Int J Cancer 1998; 76:702 - 8; http://dx.doi.org/10.1002/(SICI)1097-0215(19980529)76:5<702::AID-IJC15>3.0.CO;2-5; PMID: 9610729
  • Muller C, Laval F, Soues S, Birck C, Charcosset JY. High cell density-dependent resistance and P-glycoprotein-mediated multidrug resistance in mitoxantrone-selected Chinese hamster cells. Biochem Pharmacol 1992; 43:2091 - 102; http://dx.doi.org/10.1016/0006-2952(92)90166-G; PMID: 1376119
  • Slapak CA, Daniel JC, Levy SB. Sequential emergence of distinct resistance phenotypes in murine erythroleukemia cells under adriamycin selection: decreased anthracycline uptake precedes increased P-glycoprotein expression. Cancer Res 1990; 50:7895 - 901; PMID: 1979251
  • Slapak CA, Fracasso PM, Martell RL, Toppmeyer DL, Lecerf JM, Levy SB. Overexpression of the multidrug resistance-associated protein (MRP) gene in vincristine but not doxorubicin-selected multidrug-resistant murine erythroleukemia cells. Cancer Res 1994; 54:5607 - 13; PMID: 7923205
  • Diaz LA Jr., Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, Allen B, Bozic I, Reiter JG, Nowak MA, et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 2012; 486:537 - 40; PMID: 22722843
  • Blagosklonny MV. STI-571 must select for drug-resistant cells but ‘no cell breathes fire out of its nostrils like a dragon’. Leukemia 2002; 16:570 - 2; http://dx.doi.org/10.1038/sj.leu.2402409; PMID: 11960334
  • Zuo C, Zhang H, Spencer HJ, Vural E, Suen JY, Schichman SA, Smoller BR, Kokoska MS, Fan CY. Increased microsatellite instability and epigenetic inactivation of the hMLH1 gene in head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg 2009; 141:484 - 90; http://dx.doi.org/10.1016/j.otohns.2009.07.007; PMID: 19786217
  • Bennett KL, Romigh T, Eng C. AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma. PLoS One 2009; 4:e6931; http://dx.doi.org/10.1371/journal.pone.0006931; PMID: 19742317
  • Masuyama H, Suwaki N, Tateishi Y, Nakatsukasa H, Segawa T, Hiramatsu Y. The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion. Mol Endocrinol 2005; 19:1170 - 80; http://dx.doi.org/10.1210/me.2004-0434; PMID: 15650019
  • Masuyama H, Nakatsukasa H, Takamoto N, Hiramatsu Y. Down-regulation of pregnane X receptor contributes to cell growth inhibition and apoptosis by anticancer agents in endometrial cancer cells. Mol Pharmacol 2007; 72:1045 - 53; http://dx.doi.org/10.1124/mol.107.037937; PMID: 17636047
  • Rigalli JP, Reuter T, Herold-Mende C, Dyckhoff G, Haefeli WE, Weiss J, Theile D. Minor role of pregnane-x-receptor for acquired multidrug resistance in head and neck squamous cell carcinoma in vitro. Cancer Chemother Pharmacol 2013; 71:1335 - 43; http://dx.doi.org/10.1007/s00280-013-2133-x; PMID: 23479137
  • Braakhuis BJ, van Dongen GA, Bagnay M, van Walsum M, Snow GB. Preclinical chemotherapy on human head and neck cancer xenografts grown in athymic nude mice. Head Neck 1989; 11:511 - 5; http://dx.doi.org/10.1002/hed.2880110607; PMID: 2584006
  • Rottenberg S, Borst P. Drug resistance in the mouse cancer clinic. Drug Resist Updat 2012; 15:81 - 9; http://dx.doi.org/10.1016/j.drup.2012.01.001; PMID: 22335919
  • Freier K, Hofele C, Knoepfle K, Gross M, Devens F, Dyckhoff G, Plinkert P, Lichter P, Herold-Mende C. Cytogenetic characterization of head and neck squamous cell carcinoma cell lines as model systems for the functional analyses of tumor-associated genes. J Oral Pathol Med 2010; 39:382 - 9; PMID: 20149059
  • Ninck S, Reisser C, Dyckhoff G, Helmke B, Bauer H, Herold-Mende C. Expression profiles of angiogenic growth factors in squamous cell carcinomas of the head and neck. Int J Cancer 2003; 106:34 - 44; http://dx.doi.org/10.1002/ijc.11188; PMID: 12794754
  • Fujita K, Sano D, Kimura M, Yamashita Y, Kawakami M, Ishiguro Y, Nishimura G, Matsuda H, Tsukuda M. Anti-tumor effects of bevacizumab in combination with paclitaxel on head and neck squamous cell carcinoma. Oncol Rep 2007; 18:47 - 51; PMID: 17549344
  • Nozawa H, Tadakuma T, Ono T, Sato M, Hiroi S, Masumoto K, Sato Y. Small interfering RNA targeting epidermal growth factor receptor enhances chemosensitivity to cisplatin, 5-fluorouracil and docetaxel in head and neck squamous cell carcinoma. Cancer Sci 2006; 97:1115 - 24; http://dx.doi.org/10.1111/j.1349-7006.2006.00287.x; PMID: 16984384
  • Stoeltzing O, Liu W, Reinmuth N, Fan F, Parry GC, Parikh AA, McCarty MF, Bucana CD, Mazar AP, Ellis LM. Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. Int J Cancer 2003; 104:496 - 503; http://dx.doi.org/10.1002/ijc.10958; PMID: 12584749
  • Jung C, Kim C. Segmenting clustered nuclei using H-minima transform-based marker extraction and contour parameterization. IEEE Trans Biomed Eng 2010; 57:2600 - 4; http://dx.doi.org/10.1109/TBME.2010.2060336; PMID: 20656653
  • Beucher S. The watershed transformation applied to image segmentation. Scanning Microsc Int 1992; 6:299 - 314
  • Ruifrok AC, Johnston DA. Quantification of histochemical staining by color deconvolution. Anal Quant Cytol Histol 2001; 23:291 - 9; PMID: 11531144
  • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3:RESEARCH0034; http://dx.doi.org/10.1186/gb-2002-3-7-research0034; PMID: 12184808
  • Albermann N, Schmitz-Winnenthal FH, Z’graggen K, Volk C, Hoffmann MM, Haefeli WE, Weiss J. Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver. Biochem Pharmacol 2005; 70:949 - 58; http://dx.doi.org/10.1016/j.bcp.2005.06.018; PMID: 16054595

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