Context-dependent regulation of Musashi-mediated mRNA translation and cell cycle regulation.

References

• Nishimoto Y, Okano H. New insight into cancer therapeutics: Induction of differentiation by regulating the Musashi/Numb/Notch pathway. Cell Res 2010; 20:1083 - 1085
   PubMed Web of Science ®Google Scholar
• Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T. Function of RNA-binding protein Musashi-1 in stem cells. Exp Cell Res 2005; 306:349 - 356
   PubMed Web of Science ®Google Scholar
• Nakamura M, Okano H, Blendy JA, Montell C. Musashi, neural RNA-binding protein required for Drosophila adult external sensory organ development. Neuron 1994; 13:67 - 81
   PubMed Web of Science ®Google Scholar
• Sakakibara S, Nakamura Y, Yoshida T, Shibata S, Koike M, Takano H, et al. RNA-binding protein Musashi family: Roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation. Proc Natl Acad Sci USA 2002; 99:15194 - 15199
   PubMed Web of Science ®Google Scholar
• Asai R, Okano H, Yasugi S. Correlation between Musashi-1 and c-hairy-1 expression and cell proliferation activity in the developing intestine and stomach of both chicken and mouse. Dev Growth Differ 2005; 47:501 - 510
   PubMed Web of Science ®Google Scholar
• Wang XY, Yin Y, Yuan H, Sakamaki T, Okano H, Glazer RI. Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathways. Mol Cell Biol 2008; 28:3589 - 3599
   PubMed Web of Science ®Google Scholar
• Kharas MG, Lengner CJ, Al-Shahrour F, Bullinger L, Ball B, Zaidi S, et al. Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nat Med 2010; 16:903 - 908
   PubMed Web of Science ®Google Scholar
• Hope KJ, Cellot S, Ting SB, MacRae T, Mayotte N, Iscove NN, et al. An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell 7:101 - 113
   PubMed Web of Science ®Google Scholar
• Hemmati HD, Nakano I, Lazareff JA, Masterman-Smith M, Geschwind DH, Bronner-Fraser M, et al. Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci USA 2003; 100:15178 - 15183
   PubMed Web of Science ®Google Scholar
• Kanemura Y, Mori K, Sakakibara S, Fujikawa H, Hayashi H, Nakano A, et al. Musashi1, an evolutionarily conserved neural RNA-binding protein, is a versatile marker of human glioma cells in determining their cellular origin, malignancy and proliferative activity. Differentiation 2001; 68:141 - 152
   PubMed Web of Science ®Google Scholar
• Toda M, Iizuka Y, Yu W, Imai T, Ikeda E, Yoshida K, et al. Expression of the neural RNA-binding protein Musashi1 in human gliomas. Glia 2001; 34:1 - 7
   PubMed Web of Science ®Google Scholar
• Yokota N, Mainprize TG, Taylor MD, Kohata T, Loreto M, Ueda S, Dura W, et al. Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization. Oncogene 2004; 23:3444 - 3453
   PubMed Web of Science ®Google Scholar
• Clarke RB, Spence K, Anderson E, Howell A, Okano H, Potten CS. A putative human breast stem cell population is enriched for steroid receptor-positive cells. Dev Biol 2005; 277:443 - 456
   PubMed Web of Science ®Google Scholar
• Clarke RB, Anderson E, Howell A, Potten CS. Regulation of human breast epithelial stem cells. Cell Prolif 2003; 36:45 - 58
   PubMed Web of Science ®Google Scholar
• Kayahara T, Sawada M, Takaishi S, Fukui H, Seno H, Fukuzawa H, et al. Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine. FEBS Lett 2003; 535:131 - 135
   PubMed Web of Science ®Google Scholar
• Sanchez-Diaz PC, Burton TL, Burns SC, Hung JY, Penalva LO. Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy. BMC cancer 2008; 8:280
   PubMed Web of Science ®Google Scholar
• Sureban SM, May R, George RJ, Dieckgraefe BK, McLeod HL, Ramalingam S, et al. Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo. Gastroenterology 2008; 134:1448 - 1458
   PubMed Web of Science ®Google Scholar
• Ito T, Kwon HY, Zimdahl B, Congdon KL, Blum J, Lento WE, et al. Regulation of myeloid leukaemia by the cell-fate determinant Musashi. Nature 2010; 466:765 - 768
   PubMed Web of Science ®Google Scholar
• Bobryshev YV, Freeman AK, Botelho NK, Tran D, Levert-Mignon AJ, Lord RV. Expression of the putative stem cell marker Musashi-1 in Barrett's esophagus and esophageal adenocarcinoma. Dis Esophagus 2010; 23:580 - 589
   PubMed Web of Science ®Google Scholar
• Arumugam K, Wang Y, Hardy LL, MacNicol MC, MacNicol AM. Enforcing temporal control of maternal mRNA translation during oocyte cell cycle progression. EMBO J 2010; 29:387 - 397
   PubMed Web of Science ®Google Scholar
• Charlesworth A, Wilczynska A, Thampi P, Cox LL, MacNicol AM. Musashi regulates the temporal order of mRNA translation during Xenopus oocyte maturation. EMBO J 2006; 25:2792 - 2801
   PubMed Web of Science ®Google Scholar
• Imai T, Tokunaga A, Yoshida T, Hashimoto M, Mikoshiba K, Weinmaster G, et al. The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA. Mol Cell Biol 2001; 21:3888 - 3900
   PubMed Web of Science ®Google Scholar
• Miyanoiri Y, Kobayashi H, Imai T, Watanabe M, Nagata T, Uesugi S, et al. Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials and backbone dynamics. J Biol Chem 2003; 278:41309 - 41315
   PubMed Web of Science ®Google Scholar
• de Sousa Abreu R, Sanchez-Diaz PC, Vogel C, Burns SC, Ko D, Burton TL, et al. Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes. J Biol Chem 2009; 284:12125 - 12135
   PubMed Web of Science ®Google Scholar
• Battelli C, Nikopoulos GN, Mitchell JG, Verdi JM. The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21(WAF-1). Mol Cell Neurosci 2006; 31:85 - 96
   PubMed Web of Science ®Google Scholar
• Wakamatsu Y, Maynard TM, Jones SU, Weston JA. NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1. Neuron 1999; 23:71 - 81
   PubMed Web of Science ®Google Scholar
• Kabos P, Kabosova A, Neuman T. Blocking HES1 expression initiates GABAergic differentiation and induces the expression of p21(CIP1/WAF1) in human neural stem cells. J Biol Chem 2002; 277:8763 - 8766
   PubMed Web of Science ®Google Scholar
• MacNicol MC, MacNicol AM. Developmental timing of mRNA translation—integration of distinct regulatory elements. Mol Reprod Dev 2010; 77:662 - 669
   PubMed Web of Science ®Google Scholar
• Kawahara H, Imai T, Imataka H, Tsujimoto M, Matsumoto K, Okano H. Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP. J Cell Biol 2008; 181:639 - 653
   PubMed Web of Science ®Google Scholar
• Okano H, Imai T, Okabe M. Musashi: A translational regulator of cell fate. J Cell Sci 2002; 115:1355 - 1359
   PubMed Web of Science ®Google Scholar
• Sakakibara S, Okano H. Expression of neural RNA-binding proteins in the postnatal CNS: implications of their roles in neuronal and glial cell development. J Neurosci 1997; 17:8300 - 8312
   PubMed Web of Science ®Google Scholar
• Ratti A, Fallini C, Cova L, Fantozzi R, Calzarossa C, Zennaro E, et al. A role for the ELAV RNA-binding proteins in neural stem cells: stabilization of Msi1 mRNA. J Cell Sci 2006; 119:1442 - 1452
   PubMed Web of Science ®Google Scholar
• Kuwako K, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, et al. Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Neuron 2010; 67:407 - 421
   PubMed Web of Science ®Google Scholar
• Richter JD. CPEB: A life in translation. Trends Biochem Sci 2007; 32:279 - 285
   PubMed Web of Science ®Google Scholar
• Nakamura Y, Sakakibara S, Miyata T, Ogawa M, Shimazaki T, Weiss S, et al. The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells. J Neurosci 2000; 20:283 - 293
   PubMed Web of Science ®Google Scholar
• Cao QL, Howard RM, Dennison JB, Whittemore SR. Differentiation of engrafted neuronal-restricted precursor cells is inhibited in the traumatically injured spinal cord. Experimental neurology 2002; 177:349 - 359
   PubMed Web of Science ®Google Scholar