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Oncogenic transcription factors as master regulators of chromatin topology

A new role for ERG in prostate cancer

, &
Pages 3380-3383 | Published online: 23 Aug 2012

References

  • Osborne CS, Chakalova L, Brown KE, Carter D, Horton A, Debrand E, et al. Active genes dynamically colocalize to shared sites of ongoing transcription. Nat Genet 2004; 36:1065 - 71; http://dx.doi.org/10.1038/ng1423; PMID: 15361872
  • Sexton T, Schober H, Fraser P, Gasser SM. Gene regulation through nuclear organization. Nat Struct Mol Biol 2007; 14:1049 - 55; http://dx.doi.org/10.1038/nsmb1324; PMID: 17984967
  • Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 2009; 326:289 - 93; http://dx.doi.org/10.1126/science.1181369; PMID: 19815776
  • Dixon JR, Selvaraj S, Yue F, Kim A, Li Y, Shen Y, et al. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 2012; 485:376 - 80; http://dx.doi.org/10.1038/nature11082; PMID: 22495300
  • Zhang Y, McCord RP, Ho YJ, Lajoie BR, Hildebrand DG, Simon AC, et al. Spatial organization of the mouse genome and its role in recurrent chromosomal translocations. Cell 2012; 148:908 - 21; http://dx.doi.org/10.1016/j.cell.2012.02.002; PMID: 22341456
  • Sexton T, Yaffe E, Kenigsberg E, Bantignies F, Leblanc B, Hoichman M, et al. Three-dimensional folding and functional organization principles of the Drosophila genome. Cell 2012; 148:458 - 72; http://dx.doi.org/10.1016/j.cell.2012.01.010; PMID: 22265598
  • Duan Z, Andronescu M, Schutz K, McIlwain S, Kim YJ, Lee C, et al. A three-dimensional model of the yeast genome. Nature 2010; 465:363 - 7; http://dx.doi.org/10.1038/nature08973; PMID: 20436457
  • De S, Michor F. DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes. Nat Biotechnol 2011; 29:1103 - 8; http://dx.doi.org/10.1038/nbt.2030; PMID: 22101487
  • Fudenberg G, Getz G, Meyerson M, Mirny LA. High order chromatin architecture shapes the landscape of chromosomal alterations in cancer. Nat Biotechnol 2011; 29:1109 - 13; http://dx.doi.org/10.1038/nbt.2049; PMID: 22101486
  • Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, et al. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod Pathol 2008; 21:1156 - 67; http://dx.doi.org/10.1038/modpathol.2008.111; PMID: 18567993
  • Koh CM, Bieberich CJ, Dang CV, Nelson WG, Yegnasubramanian S, De Marzo AM. MYC and Prostate Cancer. Genes Cancer 2010; 1:617 - 28; http://dx.doi.org/10.1177/1947601910379132; PMID: 21779461
  • Perner S, Mosquera JM, Demichelis F, Hofer MD, Paris PL, Simko J, et al. TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion. Am J Surg Pathol 2007; 31:882 - 8; http://dx.doi.org/10.1097/01.pas.0000213424.38503.aa; PMID: 17527075
  • Delattre O, Zucman J, Melot T, Garau XS, Zucker JM, Lenoir GM, et al. The Ewing family of tumors--a subgroup of small-round-cell tumors defined by specific chimeric transcripts. N Engl J Med 1994; 331:294 - 9; http://dx.doi.org/10.1056/NEJM199408043310503; PMID: 8022439
  • Dalla-Favera R, Bregni M, Erikson J, Patterson D, Gallo RC, Croce CM. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc Natl Acad Sci U S A 1982; 79:7824 - 7; http://dx.doi.org/10.1073/pnas.79.24.7824; PMID: 6961453
  • Klezovitch O, Risk M, Coleman I, Lucas JM, Null M, True LD, et al. A causal role for ERG in neoplastic transformation of prostate epithelium. Proc Natl Acad Sci U S A 2008; 105:2105 - 10; http://dx.doi.org/10.1073/pnas.0711711105; PMID: 18245377
  • Rickman DS, Chen YB, Banerjee S, Pan Y, Yu J, Vuong T, et al. ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression. Neoplasia 2010; 12:1031 - 40; PMID: 21170267
  • Tomlins SA, Laxman B, Varambally S, Cao X, Yu J, Helgeson BE, et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 2008; 10:177 - 88; http://dx.doi.org/10.1593/neo.07822; PMID: 18283340
  • Koh CM, Iwata T, Zheng Q, Bethel C, Yegnasubramanian S, De Marzo AM. Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms. Oncotarget 2011; 2:669 - 83; PMID: 21941025
  • Yu J, Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell 2010; 17:443 - 54; http://dx.doi.org/10.1016/j.ccr.2010.03.018; PMID: 20478527
  • Rickman DS, Soong TD, Moss B, Mosquera JM, Dlabal J, Terry S, et al. Oncogene-mediated alterations in chromatin conformation. Proc Natl Acad Sci U S A 2012; 109:9083 - 8; http://dx.doi.org/10.1073/pnas.1112570109; PMID: 22615383
  • Brenner JC, Ateeq B, Li Y, Yocum AK, Cao Q, Asangani IA, et al. Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell 2011; 19:664 - 78; http://dx.doi.org/10.1016/j.ccr.2011.04.010; PMID: 21575865
  • Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, Sivachenko AY, et al. The genomic complexity of primary human prostate cancer. Nature 2011; 470:214 - 20; http://dx.doi.org/10.1038/nature09744; PMID: 21307934
  • Rausch T, Jones DT, Zapatka M, Stütz AM, Zichner T, Weischenfeldt J, et al. Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell 2012; 148:59 - 71; http://dx.doi.org/10.1016/j.cell.2011.12.013; PMID: 22265402
  • Marti-Renom MA, Mirny LA. Bridging the resolution gap in structural modeling of 3D genome organization. PLoS Comput Biol 2011; 7:e1002125; http://dx.doi.org/10.1371/journal.pcbi.1002125; PMID: 21779160
  • Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR, Mudie LJ, et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 2011; 144:27 - 40; http://dx.doi.org/10.1016/j.cell.2010.11.055; PMID: 21215367
  • Hollenhorst PC, Shah AA, Hopkins C, Graves BJ. Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev 2007; 21:1882 - 94; http://dx.doi.org/10.1101/gad.1561707; PMID: 17652178
  • Dominguez-Sola D, Ying CY, Grandori C, Ruggiero L, Chen B, Li M, et al. Non-transcriptional control of DNA replication by c-Myc. Nature 2007; 448:445 - 51; http://dx.doi.org/10.1038/nature05953; PMID: 17597761

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