1,160
Views
22
CrossRef citations to date
0
Altmetric
Report

Nek9 regulates spindle organization and cell cycle progression during mouse oocyte meiosis and its location in early embryo mitosis

, , , , , , , , , , & show all
Pages 4366-4377 | Published online: 16 Nov 2012

References

  • Niikura Y, Niikura T, Tilly JL. Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment. Aging (Albany NY) 2009; 1:971 - 8; PMID: 20157580
  • Niikura Y, Niikura T, Wang N, Satirapod C, Tilly JL. Systemic signals in aged males exert potent rejuvenating effects on the ovarian follicle reserve in mammalian females. Aging (Albany NY) 2010; 2:999 - 1003; PMID: 21212462
  • Homer H, Gui L, Carroll J. A spindle assembly checkpoint protein functions in prophase I arrest and prometaphase progression. Science 2009; 326:991 - 4; http://dx.doi.org/10.1126/science.1175326; PMID: 19965510
  • Fry AM. The Nek2 protein kinase: a novel regulator of centrosome structure. Oncogene 2002; 21:6184 - 94; http://dx.doi.org/10.1038/sj.onc.1205711; PMID: 12214248
  • Carabatsos MJ, Combelles CM, Messinger SM, Albertini DF. Sorting and reorganization of centrosomes during oocyte maturation in the mouse. Microsc Res Tech 2000; 49:435 - 44; http://dx.doi.org/10.1002/(SICI)1097-0029(20000601)49:5<435::AID-JEMT5>3.0.CO;2-H; PMID: 10842370
  • Ma W, Koch JA, Viveiros MM. Protein kinase C delta (PKCdelta) interacts with microtubule organizing center (MTOC)-associated proteins and participates in meiotic spindle organization. Dev Biol 2008; 320:414 - 25; http://dx.doi.org/10.1016/j.ydbio.2008.05.550; PMID: 18602096
  • Schuh M, Ellenberg J. Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes. Cell 2007; 130:484 - 98; http://dx.doi.org/10.1016/j.cell.2007.06.025; PMID: 17693257
  • Dumont J, Petri S, Pellegrin F, Terret ME, Bohnsack MT, Rassinier P, et al. A centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytes. J Cell Biol 2007; 176:295 - 305; http://dx.doi.org/10.1083/jcb.200605199; PMID: 17261848
  • Nigg EA. Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell Biol 2001; 2:21 - 32; http://dx.doi.org/10.1038/35048096; PMID: 11413462
  • McMillin DW, Delmore J, Negri J, Ooi M, Klippel S, Miduturu CV, et al. Microenvironmental influence on pre-clinical activity of polo-like kinase inhibition in multiple myeloma: implications for clinical translation. PLoS One 2011; 6:e20226; http://dx.doi.org/10.1371/journal.pone.0020226; PMID: 21750699
  • Luo J, Liu X. Polo-like kinase 1, on the rise from cell cycle regulation to prostate cancer development. Protein Cell 2012; 3:182 - 97; http://dx.doi.org/10.1007/s13238-012-2020-y; PMID: 22447658
  • van der Waal MS, Hengeveld RC, van der Horst A, Lens SM. Cell division control by the Chromosomal Passenger Complex. Exp Cell Res 2012; 318:1407 - 20; http://dx.doi.org/10.1016/j.yexcr.2012.03.015; PMID: 22472345
  • Hégarat N, Smith E, Nayak G, Takeda S, Eyers PA, Hochegger H. Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics. J Cell Biol 2011; 195:1103 - 13; http://dx.doi.org/10.1083/jcb.201105058; PMID: 22184196
  • Salaun P, Rannou Y, Prigent C. Cdk1, Plks, Auroras, and Neks: the mitotic bodyguards. Adv Exp Med Biol 2008; 617:41 - 56; http://dx.doi.org/10.1007/978-0-387-69080-3_4; PMID: 18497029
  • Osmani SA, Ye XS. Cell cycle regulation in Aspergillus by two protein kinases. Biochem J 1996; 317:633 - 41; PMID: 8760343
  • O’Connell MJ, Krien MJ, Hunter T. Never say never. The NIMA-related protein kinases in mitotic control. Trends Cell Biol 2003; 13:221 - 8; http://dx.doi.org/10.1016/S0962-8924(03)00056-4; PMID: 12742165
  • Rapley J, Nicolàs M, Groen A, Regué L, Bertran MT, Caelles C, et al. The NIMA-family kinase Nek6 phosphorylates the kinesin Eg5 at a novel site necessary for mitotic spindle formation. J Cell Sci 2008; 121:3912 - 21; http://dx.doi.org/10.1242/jcs.035360; PMID: 19001501
  • Wu L, Osmani SA, Mirabito PM. A role for NIMA in the nuclear localization of cyclin B in Aspergillus nidulans. J Cell Biol 1998; 141:1575 - 87; http://dx.doi.org/10.1083/jcb.141.7.1575; PMID: 9647650
  • Quarmby LM, Mahjoub MR. Caught Nek-ing: cilia and centrioles. J Cell Sci 2005; 118:5161 - 9; http://dx.doi.org/10.1242/jcs.02681; PMID: 16280549
  • O’regan L, Blot J, Fry AM. Mitotic regulation by NIMA-related kinases. Cell Div 2007; 2:25; http://dx.doi.org/10.1186/1747-1028-2-25; PMID: 17727698
  • Bowers AJ, Boylan JF. Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors. Gene 2004; 328:135 - 42; http://dx.doi.org/10.1016/j.gene.2003.12.002; PMID: 15019993
  • Roig J, Mikhailov A, Belham C, Avruch J. Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression. Genes Dev 2002; 16:1640 - 58; http://dx.doi.org/10.1101/gad.972202; PMID: 12101123
  • Roig J, Groen A, Caldwell J, Avruch J. Active Nercc1 protein kinase concentrates at centrosomes early in mitosis and is necessary for proper spindle assembly. Mol Biol Cell 2005; 16:4827 - 40; http://dx.doi.org/10.1091/mbc.E05-04-0315; PMID: 16079175
  • Belham C, Roig J, Caldwell JA, Aoyama Y, Kemp BE, Comb M, et al. A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases. J Biol Chem 2003; 278:34897 - 909; http://dx.doi.org/10.1074/jbc.M303663200; PMID: 12840024
  • O’Regan L, Fry AM. The Nek6 and Nek7 protein kinases are required for robust mitotic spindle formation and cytokinesis. Mol Cell Biol 2009; 29:3975 - 90; http://dx.doi.org/10.1128/MCB.01867-08; PMID: 19414596
  • Bertran MT, Sdelci S, Regué L, Avruch J, Caelles C, Roig J. Nek9 is a Plk1-activated kinase that controls early centrosome separation through Nek6/7 and Eg5. EMBO J 2011; 30:2634 - 47; http://dx.doi.org/10.1038/emboj.2011.179; PMID: 21642957
  • Sonn S, Oh GT, Rhee K. Nek2 and its substrate, centrobin/Nip2, are required for proper meiotic spindle formation of the mouse oocytes. Zygote 2011; 19:15 - 20; http://dx.doi.org/10.1017/S0967199410000183; PMID: 20569513
  • Meng XQ, Fan HY, Zhong ZS, Zhang G, Li YL, Chen DY, et al. Localization of gamma-tubulin in mouse eggs during meiotic maturation, fertilization, and early embryonic development. J Reprod Dev 2004; 50:97 - 105; http://dx.doi.org/10.1262/jrd.50.97; PMID: 15007207
  • Xiong B, Sun SC, Lin SL, Li M, Xu BZ, OuYang YC, et al. Involvement of Polo-like kinase 1 in MEK1/2-regulated spindle formation during mouse oocyte meiosis. Cell Cycle 2008; 7:1804 - 9; http://dx.doi.org/10.4161/cc.7.12.6019; PMID: 18583944
  • Yan LY, Huang JC, Zhu ZY, Lei ZL, Shi LH, Nan CL, et al. NuMA distribution and microtubule configuration in rabbit oocytes and cloned embryos. Reproduction 2006; 132:869 - 76; http://dx.doi.org/10.1530/rep.1.01224; PMID: 17127747
  • Ou XH, Li S, Xu BZ, Wang ZB, Quan S, Li M, et al. p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation. Cell Cycle 2010; 9:4130 - 43; http://dx.doi.org/10.4161/cc.9.20.13389; PMID: 20948319
  • Zhang CH, Wang ZB, Quan S, Huang X, Tong JS, Ma JY, et al. GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte. Cell Cycle 2011; 10:1861 - 70; http://dx.doi.org/10.4161/cc.10.11.15797; PMID: 21552007
  • Nigg EA. Polo-like kinases: positive regulators of cell division from start to finish. Curr Opin Cell Biol 1998; 10:776 - 83; http://dx.doi.org/10.1016/S0955-0674(98)80121-X; PMID: 9914175
  • Tong C, Fan HY, Lian L, Li SW, Chen DY, Schatten H, et al. Polo-like kinase-1 is a pivotal regulator of microtubule assembly during mouse oocyte meiotic maturation, fertilization, and early embryonic mitosis. Biol Reprod 2002; 67:546 - 54; http://dx.doi.org/10.1095/biolreprod67.2.546; PMID: 12135894
  • Kim S, Lee K, Rhee K. NEK7 is a centrosomal kinase critical for microtubule nucleation. Biochem Biophys Res Commun 2007; 360:56 - 62; http://dx.doi.org/10.1016/j.bbrc.2007.05.206; PMID: 17586473
  • Yin MJ, Shao L, Voehringer D, Smeal T, Jallal B. The serine/threonine kinase Nek6 is required for cell cycle progression through mitosis. J Biol Chem 2003; 278:52454 - 60; http://dx.doi.org/10.1074/jbc.M308080200; PMID: 14563848
  • Wiese C, Zheng Y. Microtubule nucleation: gamma-tubulin and beyond. J Cell Sci 2006; 119:4143 - 53; http://dx.doi.org/10.1242/jcs.03226; PMID: 17038541
  • Ma W, Baumann C, Viveiros MM. NEDD1 is crucial for meiotic spindle stability and accurate chromosome segregation in mammalian oocytes. Dev Biol 2010; 339:439 - 50; http://dx.doi.org/10.1016/j.ydbio.2010.01.009; PMID: 20079731
  • Haren L, Remy MH, Bazin I, Callebaut I, Wright M, Merdes A. NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. J Cell Biol 2006; 172:505 - 15; http://dx.doi.org/10.1083/jcb.200510028; PMID: 16461362
  • Haren L, Stearns T, Lüders J. Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components. PLoS One 2009; 4:e5976; http://dx.doi.org/10.1371/journal.pone.0005976; PMID: 19543530
  • Sdelci S, Schütz M, Pinyol R, Bertran MT, Regué L, Caelles C, et al. Nek9 phosphorylation of NEDD1/GCP-WD contributes to Plk1 control of γ-tubulin recruitment to the mitotic centrosome. Curr Biol 2012; 22:1516 - 23; http://dx.doi.org/10.1016/j.cub.2012.06.027; PMID: 22818914
  • Kalab P, Heald R. The RanGTP gradient - a GPS for the mitotic spindle. J Cell Sci 2008; 121:1577 - 86; http://dx.doi.org/10.1242/jcs.005959; PMID: 18469014
  • Clarke PR, Zhang C. Spatial and temporal coordination of mitosis by Ran GTPase. Nat Rev Mol Cell Biol 2008; 9:464 - 77; http://dx.doi.org/10.1038/nrm2410; PMID: 18478030
  • Kaláb P, Solc P, Motlík J. The role of RanGTP gradient in vertebrate oocyte maturation. Results Probl Cell Differ 2011; 53:235 - 67; http://dx.doi.org/10.1007/978-3-642-19065-0_12; PMID: 21630149
  • Wei L, Liang XW, Zhang QH, Li M, Yuan J, Li S, et al. BubR1 is a spindle assembly checkpoint protein regulating meiotic cell cycle progression of mouse oocyte. Cell Cycle 2010; 9:1112 - 21; http://dx.doi.org/10.4161/cc.9.6.10957; PMID: 20237433
  • Li M, Li S, Yuan J, Wang ZB, Sun SC, Schatten H, et al. Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis. PLoS One 2009; 4:e7701; http://dx.doi.org/10.1371/journal.pone.0007701; PMID: 19888327
  • Althoff F, Karess RE, Lehner CF. Spindle checkpoint-independent inhibition of mitotic chromosome segregation by Drosophila Mps1. Mol Biol Cell 2012; 23:2275 - 91; http://dx.doi.org/10.1091/mbc.E12-02-0117; PMID: 22553353
  • Hached K, Xie SZ, Buffin E, Cladière D, Rachez C, Sacras M, et al. Mps1 at kinetochores is essential for female mouse meiosis I. Development 2011; 138:2261 - 71; http://dx.doi.org/10.1242/dev.061317; PMID: 21558374
  • Homer HA. Mad2 and spindle assembly checkpoint function during meiosis I in mammalian oocytes. Histol Histopathol 2006; 21:873 - 86; PMID: 16691540
  • Bannon JH, O’Donovan DS, Kennelly SM, Mc Gee MM. The peptidyl prolyl isomerase cyclophilin A localizes at the centrosome and the midbody and is required for cytokinesis. Cell Cycle 2012; 11:1340 - 53; http://dx.doi.org/10.4161/cc.19711; PMID: 22421161
  • Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA. The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis. Cell Cycle 2009; 8:2385 - 98; http://dx.doi.org/10.4161/cc.8.15.9082; PMID: 19556893
  • Vazquez-Martin A, Oliveras-Ferraros C, Cufí S, Menendez JA. Polo-like kinase 1 regulates activation of AMP-activated protein kinase (AMPK) at the mitotic apparatus. Cell Cycle 2011; 10:1295 - 302; http://dx.doi.org/10.4161/cc.10.8.15342; PMID: 21474997
  • Vazquez-Martin A, Cufí S, Oliveras-Ferraros C, Menendez JA. Polo-like kinase 1 directs the AMPK-mediated activation of myosin regulatory light chain at the cytokinetic cleavage furrow independently of energy balance. Cell Cycle 2012; 11:2422 - 6; http://dx.doi.org/10.4161/cc.20438; PMID: 22672936
  • Li J, Wang J, Hou W, Jing Z, Tian C, Han Y, et al. Phosphorylation of Ataxin-10 by polo-like kinase 1 is required for cytokinesis. Cell Cycle 2011; 10:2946 - 58; http://dx.doi.org/10.4161/cc.10.17.15922; PMID: 21857149
  • Wei Y, Multi S, Yang CR, Ma J, Zhang QH, Wang ZB, et al. Spindle assembly checkpoint regulates mitotic cell cycle progression during preimplantation embryo development. PLoS One 2011; 6:e21557; http://dx.doi.org/10.1371/journal.pone.0021557; PMID: 21720555
  • Sun SC, Wei L, Li M, Lin SL, Xu BZ, Liang XW, et al. Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse oocyte meiotic maturation. Cell Cycle 2009; 8:3365 - 72; http://dx.doi.org/10.4161/cc.8.20.9855; PMID: 19806029
  • Verlhac MH, Lefebvre C, Guillaud P, Rassinier P, Maro B. Asymmetric division in mouse oocytes: with or without Mos. Curr Biol 2000; 10:1303 - 6; http://dx.doi.org/10.1016/S0960-9822(00)00753-3; PMID: 11069114

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.