Downregulation of Cdc6 and pre-replication complexes in response to methionine stress in breast cancer cells

References

• Kroemer G, Pouyssegur J. Tumor cell metabolism: cancer’s Achilles’ heel. Cancer Cell 2008; 13:472 - 82; http://dx.doi.org/10.1016/j.ccr.2008.05.005; PMID: 18538731
   PubMed Web of Science ®Google Scholar
• Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646 - 74; http://dx.doi.org/10.1016/j.cell.2011.02.013; PMID: 21376230
   PubMed Web of Science ®Google Scholar
• Hsu PP, Sabatini DM. Cancer cell metabolism: Warburg and beyond. Cell 2008; 134:703 - 7; http://dx.doi.org/10.1016/j.cell.2008.08.021; PMID: 18775299
   PubMed Web of Science ®Google Scholar
• Ward PS, Thompson CB. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 2012; 21:297 - 308; http://dx.doi.org/10.1016/j.ccr.2012.02.014; PMID: 22439925
   PubMed Web of Science ®Google Scholar
• Cellarier E, Durando X, Vasson MP, Farges MC, Demiden A, Maurizis JC, et al. Methionine dependency and cancer treatment. Cancer Treat Rev 2003; 29:489 - 99; http://dx.doi.org/10.1016/S0305-7372(03)00118-X; PMID: 14585259
   PubMed Web of Science ®Google Scholar
• Halpern BC, Clark BR, Hardy DN, Halpern RM, Smith RA. The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture. Proc Natl Acad Sci USA 1974; 71:1133 - 6; http://dx.doi.org/10.1073/pnas.71.4.1133; PMID: 4524624
   PubMed Web of Science ®Google Scholar
• Mecham JO, Rowitch D, Wallace CD, Stern PH, Hoffman RM. The metabolic defect of methionine dependence occurs frequently in human tumor cell lines. Biochem Biophys Res Commun 1983; 117:429 - 34; http://dx.doi.org/10.1016/0006-291X(83)91218-4; PMID: 6661235
   PubMed Web of Science ®Google Scholar
• Stern PH, Wallace CD, Hoffman RM. Altered methionine metabolism occurs in all members of a set of diverse human tumor cell lines. J Cell Physiol 1984; 119:29 - 34; http://dx.doi.org/10.1002/jcp.1041190106; PMID: 6707100
   PubMed Web of Science ®Google Scholar
• Hoffman RM, Erbe RW. High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine. Proc Natl Acad Sci USA 1976; 73:1523 - 7; http://dx.doi.org/10.1073/pnas.73.5.1523; PMID: 179090
   PubMed Web of Science ®Google Scholar
• Lu S, Epner DE. Molecular mechanisms of cell cycle block by methionine restriction in human prostate cancer cells. Nutr Cancer 2000; 38:123 - 30; http://dx.doi.org/10.1207/S15327914NC381_17; PMID: 11341037
   PubMed Web of Science ®Google Scholar
• Kokkinakis DM, Liu X, Chada S, Ahmed MM, Shareef MM, Singha UK, et al. Modulation of gene expression in human central nervous system tumors under methionine deprivation-induced stress. Cancer Res 2004; 64:7513 - 25; http://dx.doi.org/10.1158/0008-5472.CAN-04-0592; PMID: 15492278
   PubMed Web of Science ®Google Scholar
• Breillout F, Hadida F, Echinard-Garin P, Lascaux V, Poupon MF. Decreased rat rhabdomyosarcoma pulmonary metastases in response to a low methionine diet. Anticancer Res 1987; 7:4B 861 - 7; PMID: 3674775
   PubMed Web of Science ®Google Scholar
• Guo H, Lishko VK, Herrera H, Groce A, Kubota T, Hoffman RM. Therapeutic tumor-specific cell cycle block induced by methionine starvation in vivo. Cancer Res 1993; 53:5676 - 9; PMID: 8242623
   PubMed Web of Science ®Google Scholar
• Tisdale MJ, Jack GW, Eridani S. Differential sensitivity of normal and leukaemic haemopoietic cells to methionine deprivation by L-methioninase. Leuk Res 1983; 7:269 - 77; http://dx.doi.org/10.1016/0145-2126(83)90017-6; PMID: 6855269
   PubMed Web of Science ®Google Scholar
• Pirotte B, Goldman S, Massager N, David P, Wikler D, Vandesteene A, et al. Comparison of 18F-FDG and 11C-methionine for PET-guided stereotactic brain biopsy of gliomas. J Nucl Med 2004; 45:1293 - 8; PMID: 15299051
   PubMed Web of Science ®Google Scholar
• Attia RR, Gardner LA, Mahrous E, Taxman DJ, Legros L, Rowe S, et al. Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis. J Biol Chem 2008; 283:30788 - 95; http://dx.doi.org/10.1074/jbc.M804159200; PMID: 18753136
   PubMed Web of Science ®Google Scholar
• Jani TS, Gobejishvili L, Hote PT, Barve AS, Joshi-Barve S, Kharebava G, et al. Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells. Cell Res 2009; 19:358 - 69; http://dx.doi.org/10.1038/cr.2008.314; PMID: 19048023
   PubMed Web of Science ®Google Scholar
• Kaiser P, Su NY, Yen JL, Ouni I, Flick K. The yeast ubiquitin ligase SCFMet30: connecting environmental and intracellular conditions to cell division. Cell Div 2006; 1:16; http://dx.doi.org/10.1186/1747-1028-1-16; PMID: 16895602
   PubMed Web of Science ®Google Scholar
• Su NY, Flick K, Kaiser P. The F-box protein Met30 is required for multiple steps in the budding yeast cell cycle. Mol Cell Biol 2005; 25:3875 - 85; http://dx.doi.org/10.1128/MCB.25.10.3875-3885.2005; PMID: 15870262
   PubMed Web of Science ®Google Scholar
• Thomas D, Surdin-Kerjan Y. Metabolism of sulfur amino acids in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 1997; 61:503 - 32; PMID: 9409150
   PubMed Web of Science ®Google Scholar
• Hoffman RM, Jacobsen SJ, Erbe RW. Reversion to methionine independence by malignant rat and SV40-transformed human fibroblasts. Biochem Biophys Res Commun 1978; 82:228 - 34; http://dx.doi.org/10.1016/0006-291X(78)90600-9; PMID: 208554
   PubMed Web of Science ®Google Scholar
• Hoffman RM, Jacobsen SJ, Erbe RW. Reversion to methionine independence in simian virus 40-transformed human and malignant rat fibroblasts is associated with altered ploidy and altered properties of transformation. Proc Natl Acad Sci USA 1979; 76:1313 - 7; http://dx.doi.org/10.1073/pnas.76.3.1313; PMID: 220612
   PubMed Web of Science ®Google Scholar
• Sengupta S, Peterson TR, Sabatini DM. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol Cell 2010; 40:310 - 22; http://dx.doi.org/10.1016/j.molcel.2010.09.026; PMID: 20965424
   PubMed Web of Science ®Google Scholar
• Zoncu R, Efeyan A, Sabatini DM. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 2011; 12:21 - 35; http://dx.doi.org/10.1038/nrm3025; PMID: 21157483
   PubMed Web of Science ®Google Scholar
• Goodrich DW, Wang NP, Qian YW, Lee EY, Lee WH. The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell 1991; 67:293 - 302; http://dx.doi.org/10.1016/0092-8674(91)90181-W; PMID: 1655277
   PubMed Web of Science ®Google Scholar
• Fry DW, Harvey PJ, Keller PR, Elliott WL, Meade M, Trachet E, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther 2004; 3:1427 - 38; PMID: 15542782
   PubMed Web of Science ®Google Scholar
• Bell SP, Dutta A. DNA replication in eukaryotic cells. Annu Rev Biochem 2002; 71:333 - 74; http://dx.doi.org/10.1146/annurev.biochem.71.110601.135425; PMID: 12045100
   PubMed Web of Science ®Google Scholar
• Petersen BO, Wagener C, Marinoni F, Kramer ER, Melixetian M, Lazzerini Denchi E, et al. Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1. Genes Dev 2000; 14:2330 - 43; http://dx.doi.org/10.1101/gad.832500; PMID: 10995389
   PubMed Web of Science ®Google Scholar
• Zhang W, Braun A, Bauman Z, Olteanu H, Madzelan P, Banerjee R. Expression profiling of homocysteine junction enzymes in the NCI60 panel of human cancer cell lines. Cancer Res 2005; 65:1554 - 60; http://dx.doi.org/10.1158/0008-5472.CAN-04-1554; PMID: 15735045
   PubMed Web of Science ®Google Scholar
• Lunn CL, Chrivia JC, Baldassare JJ. Activation of Cdk2/Cyclin E complexes is dependent on the origin of replication licensing factor Cdc6 in mammalian cells. Cell Cycle 2010; 9:4533 - 41; http://dx.doi.org/10.4161/cc.9.22.13789; PMID: 21088490
   PubMed Web of Science ®Google Scholar
• Sotillo E, Garriga J, Padgaonkar A, Kurimchak A, Cook JG, Graña X. Coordinated activation of the origin licensing factor CDC6 and CDK2 in resting human fibroblasts expressing SV40 small T antigen and cyclin E. J Biol Chem 2009; 284:14126 - 35; http://dx.doi.org/10.1074/jbc.M900687200; PMID: 19321444
   PubMed Web of Science ®Google Scholar
• Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P. Cdk2 knockout mice are viable. Curr Biol 2003; 13:1775 - 85; http://dx.doi.org/10.1016/j.cub.2003.09.024; PMID: 14561402
   PubMed Web of Science ®Google Scholar
• Tvegård T, Soltani H, Skjølberg HC, Krohn M, Nilssen EA, Kearsey SE, et al. A novel checkpoint mechanism regulating the G1/S transition. Genes Dev 2007; 21:649 - 54; http://dx.doi.org/10.1101/gad.421807; PMID: 17369398
   PubMed Web of Science ®Google Scholar
• Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, et al. New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 1990; 82:1107 - 12; http://dx.doi.org/10.1093/jnci/82.13.1107; PMID: 2359136
   PubMed Web of Science ®Google Scholar
• Keck JM, Summers MK, Tedesco D, Ekholm-Reed S, Chuang LC, Jackson PK, et al. Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). J Cell Biol 2007; 178:371 - 85; http://dx.doi.org/10.1083/jcb.200703202; PMID: 17664332
   PubMed Web of Science ®Google Scholar
• Méndez J, Stillman B. Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis. Mol Cell Biol 2000; 20:8602 - 12; http://dx.doi.org/10.1128/MCB.20.22.8602-8612.2000; PMID: 11046155
   PubMed Web of Science ®Google Scholar
• Pumiglia KM, Decker SJ. Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway. Proc Natl Acad Sci USA 1997; 94:448 - 52; http://dx.doi.org/10.1073/pnas.94.2.448; PMID: 9012803
   PubMed Web of Science ®Google Scholar