MicroRNAs and DNA damage response

References

• Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116:281 - 97; http://dx.doi.org/10.1016/S0092-8674(04)00045-5; PMID: 14744438
   PubMed Web of Science ®Google Scholar
• Carthew RW, Sontheimer EJ. Origins and Mechanisms of miRNAs and siRNAs. Cell 2009; 136:642 - 55; http://dx.doi.org/10.1016/j.cell.2009.01.035; PMID: 19239886
   PubMed Web of Science ®Google Scholar
• Pothof J, Verkaik NS, van IJcken W, Wiemer EA, Ta VT, van der Horst GT, et al. MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response. EMBO J 2009; 28:2090 - 9; http://dx.doi.org/10.1038/emboj.2009.156; PMID: 19536137
   PubMed Web of Science ®Google Scholar
• Wei W, Ba Z, Gao M, Wu Y, Ma Y, Amiard S, et al. A role for small RNAs in DNA double-strand break repair. Cell 2012; 149:101 - 12; http://dx.doi.org/10.1016/j.cell.2012.03.002; PMID: 22445173
   PubMed Web of Science ®Google Scholar
• Wang Y, Huang JW, Calses P, Kemp CJ, Taniguchi T. MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition. Cancer Res 2012; 72:4037 - 46; http://dx.doi.org/10.1158/0008-5472.CAN-12-0103; PMID: 22761336
   PubMed Web of Science ®Google Scholar
• Wang Y, Huang JW, Li M, Cavenee WK, Mitchell PS, Zhou X, et al. MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression. Mol Cancer Res 2011; 9:1100 - 11; http://dx.doi.org/10.1158/1541-7786.MCR-11-0007; PMID: 21693595
   PubMed Web of Science ®Google Scholar
• Lal A, Pan Y, Navarro F, Dykxhoorn DM, Moreau L, Meire E, et al. miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells. Nat Struct Mol Biol 2009; 16:492 - 8; http://dx.doi.org/10.1038/nsmb.1589; PMID: 19377482
   PubMed Web of Science ®Google Scholar
• Moskwa P, Buffa FM, Pan Y, Panchakshari R, Gottipati P, Muschel RJ, et al. miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell 2011; 41:210 - 20; http://dx.doi.org/10.1016/j.molcel.2010.12.005; PMID: 21195000
   PubMed Web of Science ®Google Scholar
• Landau DA, Slack FJ. MicroRNAs in mutagenesis, genomic instability, and DNA repair. Semin Oncol 2011; 38:743 - 51; http://dx.doi.org/10.1053/j.seminoncol.2011.08.003; PMID: 22082760
   PubMed Web of Science ®Google Scholar
• Hu H, Gatti RA. MicroRNAs: new players in the DNA damage response. J Mol Cell Biol 2011; 3:151 - 8; http://dx.doi.org/10.1093/jmcb/mjq042; PMID: 21183529
   PubMed Web of Science ®Google Scholar
• Zhang X, Lu X. Posttranscriptional regulation of miRNAs in the DNA damage response. RNA Biol 2011; 8:960 - 3; http://dx.doi.org/10.4161/rna.8.6.17337; PMID: 21941125
   PubMed Web of Science ®Google Scholar
• Ciccia A, Elledge SJ. The DNA damage response: making it safe to play with knives. Mol Cell 2010; 40:179 - 204; http://dx.doi.org/10.1016/j.molcel.2010.09.019; PMID: 20965415
   PubMed Web of Science ®Google Scholar
• Lempiäinen H, Halazonetis TD. Emerging common themes in regulation of PIKKs and PI3Ks. EMBO J 2009; 28:3067 - 73; http://dx.doi.org/10.1038/emboj.2009.281; PMID: 19779456
   PubMed Web of Science ®Google Scholar
• Bensimon A, Aebersold R, Shiloh Y. Beyond ATM: the protein kinase landscape of the DNA damage response. FEBS Lett 2011; 585:1625 - 39; http://dx.doi.org/10.1016/j.febslet.2011.05.013; PMID: 21570395
   PubMed Web of Science ®Google Scholar
• Zou L. Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response. Genes Dev 2007; 21:879 - 85; http://dx.doi.org/10.1101/gad.1550307; PMID: 17437994
   PubMed Web of Science ®Google Scholar
• MacDougall CA, Byun TS, Van C, Yee MC, Cimprich KA. The structural determinants of checkpoint activation. Genes Dev 2007; 21:898 - 903; http://dx.doi.org/10.1101/gad.1522607; PMID: 17437996
   PubMed Web of Science ®Google Scholar
• Kühne M, Riballo E, Rief N, Rothkamm K, Jeggo PA, Löbrich M. A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Res 2004; 64:500 - 8; http://dx.doi.org/10.1158/0008-5472.CAN-03-2384; PMID: 14744762
   PubMed Web of Science ®Google Scholar
• Cimprich KA, Cortez D. ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol 2008; 9:616 - 27; http://dx.doi.org/10.1038/nrm2450; PMID: 18594563
   PubMed Web of Science ®Google Scholar
• Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005; 434:917 - 21; http://dx.doi.org/10.1038/nature03445; PMID: 15829967
   PubMed Web of Science ®Google Scholar
• Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 2005; 434:913 - 7; http://dx.doi.org/10.1038/nature03443; PMID: 15829966
   PubMed Web of Science ®Google Scholar
• Dhillon KK, Swisher EM, Taniguchi T. Secondary mutations of BRCA1/2 and drug resistance. Cancer Sci 2011; 102:663 - 9; http://dx.doi.org/10.1111/j.1349-7006.2010.01840.x; PMID: 21205087
   PubMed Web of Science ®Google Scholar
• Helleday T, Petermann E, Lundin C, Hodgson B, Sharma RA. DNA repair pathways as targets for cancer therapy. Nat Rev Cancer 2008; 8:193 - 204; http://dx.doi.org/10.1038/nrc2342; PMID: 18256616
   PubMed Web of Science ®Google Scholar
• Borchert GM, Lanier W, Davidson BL. RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol 2006; 13:1097 - 101; http://dx.doi.org/10.1038/nsmb1167; PMID: 17099701
   PubMed Web of Science ®Google Scholar
• Lund E, Güttinger S, Calado A, Dahlberg JE, Kutay U. Nuclear export of microRNA precursors. Science 2004; 303:95 - 8; http://dx.doi.org/10.1126/science.1090599; PMID: 14631048
   PubMed Web of Science ®Google Scholar
• Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, et al. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 2005; 436:740 - 4; http://dx.doi.org/10.1038/nature03868; PMID: 15973356
   PubMed Web of Science ®Google Scholar
• Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 2005; 123:631 - 40; http://dx.doi.org/10.1016/j.cell.2005.10.022; PMID: 16271387
   PubMed Web of Science ®Google Scholar
• Khvorova A, Reynolds A, Jayasena SD. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003; 115:209 - 16; http://dx.doi.org/10.1016/S0092-8674(03)00801-8; PMID: 14567918
   PubMed Web of Science ®Google Scholar
• Schwarz DS, Hutvágner G, Du T, Xu Z, Aronin N, Zamore PD. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003; 115:199 - 208; http://dx.doi.org/10.1016/S0092-8674(03)00759-1; PMID: 14567917
   PubMed Web of Science ®Google Scholar
• Lytle JR, Yario TA, Steitz JA. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR. Proc Natl Acad Sci USA 2007; 104:9667 - 72; http://dx.doi.org/10.1073/pnas.0703820104; PMID: 17535905
   PubMed Web of Science ®Google Scholar
• Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 2008; 455:1124 - 8; http://dx.doi.org/10.1038/nature07299; PMID: 18806776
   PubMed Web of Science ®Google Scholar
• Pillai RS, Bhattacharyya SN, Filipowicz W. Repression of protein synthesis by miRNAs: how many mechanisms?. Trends Cell Biol 2007; 17:118 - 26; http://dx.doi.org/10.1016/j.tcb.2006.12.007; PMID: 17197185
   PubMed Web of Science ®Google Scholar
• Zisoulis DG, Kai ZS, Chang RK, Pasquinelli AE. Autoregulation of microRNA biogenesis by let-7 and Argonaute. Nature 2012; 486:541 - 4; PMID: 22722835
   PubMed Web of Science ®Google Scholar
• Babiarz JE, Ruby JG, Wang Y, Bartel DP, Blelloch R. Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev 2008; 22:2773 - 85; http://dx.doi.org/10.1101/gad.1705308; PMID: 18923076
   PubMed Web of Science ®Google Scholar
• Havens MA, Reich AA, Duelli DM, Hastings ML. Biogenesis of mammalian microRNAs by a non-canonical processing pathway. Nucleic Acids Res 2012; 40:4626 - 40; http://dx.doi.org/10.1093/nar/gks026; PMID: 22270084
   PubMed Web of Science ®Google Scholar
• Yang JS, Maurin T, Robine N, Rasmussen KD, Jeffrey KL, Chandwani R, et al. Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc Natl Acad Sci USA 2010; 107:15163 - 8; http://dx.doi.org/10.1073/pnas.1006432107; PMID: 20699384
   PubMed Web of Science ®Google Scholar
• Cheloufi S, Dos Santos CO, Chong MM, Hannon GJ. A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature 2010; 465:584 - 9; http://dx.doi.org/10.1038/nature09092; PMID: 20424607
   PubMed Web of Science ®Google Scholar
• Cifuentes D, Xue H, Taylor DW, Patnode H, Mishima Y, Cheloufi S, et al. A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science 2010; 328:1694 - 8; http://dx.doi.org/10.1126/science.1190809; PMID: 20448148
   PubMed Web of Science ®Google Scholar
• Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K, et al. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol 2007; 9:604 - 11; http://dx.doi.org/10.1038/ncb1577; PMID: 17435748
   PubMed Web of Science ®Google Scholar
• Davis BN, Hilyard AC, Lagna G, Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008; 454:56 - 61; http://dx.doi.org/10.1038/nature07086; PMID: 18548003
   PubMed Web of Science ®Google Scholar
• Davis BN, Hilyard AC, Nguyen PH, Lagna G, Hata A. Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha. Mol Cell 2010; 39:373 - 84; http://dx.doi.org/10.1016/j.molcel.2010.07.011; PMID: 20705240
   PubMed Web of Science ®Google Scholar
• Yu B, Bi L, Zheng B, Ji L, Chevalier D, Agarwal M, et al. The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis. Proc Natl Acad Sci USA 2008; 105:10073 - 8; http://dx.doi.org/10.1073/pnas.0804218105; PMID: 18632581
   PubMed Web of Science ®Google Scholar
• Kawahara Y, Mieda-Sato A. TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Proc Natl Acad Sci USA 2012; 109:3347 - 52; http://dx.doi.org/10.1073/pnas.1112427109; PMID: 22323604
   PubMed Web of Science ®Google Scholar
• Wu H, Sun S, Tu K, Gao Y, Xie B, Krainer AR, et al. A splicing-independent function of SF2/ASF in microRNA processing. Mol Cell 2010; 38:67 - 77; http://dx.doi.org/10.1016/j.molcel.2010.02.021; PMID: 20385090
   PubMed Web of Science ®Google Scholar
• Sakamoto S, Aoki K, Higuchi T, Todaka H, Morisawa K, Tamaki N, et al. The NF90-NF45 complex functions as a negative regulator in the microRNA processing pathway. Mol Cell Biol 2009; 29:3754 - 69; http://dx.doi.org/10.1128/MCB.01836-08; PMID: 19398578
   PubMed Web of Science ®Google Scholar
• Suzuki HI, Yamagata K, Sugimoto K, Iwamoto T, Kato S, Miyazono K. Modulation of microRNA processing by p53. Nature 2009; 460:529 - 33; http://dx.doi.org/10.1038/nature08199; PMID: 19626115
   PubMed Web of Science ®Google Scholar
• Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, et al. Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell 2009; 36:340 - 7; http://dx.doi.org/10.1016/j.molcel.2009.08.017; PMID: 19854141
   PubMed Web of Science ®Google Scholar
• Suzuki HI, Arase M, Matsuyama H, Choi YL, Ueno T, Mano H, et al. MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation. Mol Cell 2011; 44:424 - 36; http://dx.doi.org/10.1016/j.molcel.2011.09.012; PMID: 22055188
   PubMed Web of Science ®Google Scholar
• Cai Y, Yu X, Hu S, Yu J. A brief review on the mechanisms of miRNA regulation. Genomics Proteomics Bioinformatics 2009; 7:147 - 54; http://dx.doi.org/10.1016/S1672-0229(08)60044-3; PMID: 20172487
   PubMedGoogle Scholar
• Kawahara Y, Megraw M, Kreider E, Iizasa H, Valente L, Hatzigeorgiou AG, et al. Frequency and fate of microRNA editing in human brain. Nucleic Acids Res 2008; 36:5270 - 80; http://dx.doi.org/10.1093/nar/gkn479; PMID: 18684997
   PubMed Web of Science ®Google Scholar
• Luciano DJ, Mirsky H, Vendetti NJ, Maas S. RNA editing of a miRNA precursor. RNA 2004; 10:1174 - 7; http://dx.doi.org/10.1261/rna.7350304; PMID: 15272117
   PubMed Web of Science ®Google Scholar
• Yang W, Chendrimada TP, Wang Q, Higuchi M, Seeburg PH, Shiekhattar R, et al. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol 2006; 13:13 - 21; http://dx.doi.org/10.1038/nsmb1041; PMID: 16369484
   PubMed Web of Science ®Google Scholar
• Kawahara Y, Zinshteyn B, Sethupathy P, Iizasa H, Hatzigeorgiou AG, Nishikura K. Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science 2007; 315:1137 - 40; http://dx.doi.org/10.1126/science.1138050; PMID: 17322061
   PubMed Web of Science ®Google Scholar
• Newman MA, Mani V, Hammond SM. Deep sequencing of microRNA precursors reveals extensive 3′ end modification. RNA 2011; 17:1795 - 803; http://dx.doi.org/10.1261/rna.2713611; PMID: 21849429
   PubMed Web of Science ®Google Scholar
• Heo I, Joo C, Cho J, Ha M, Han J, Kim VN. Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 2008; 32:276 - 84; http://dx.doi.org/10.1016/j.molcel.2008.09.014; PMID: 18951094
   PubMed Web of Science ®Google Scholar
• Heo I, Joo C, Kim YK, Ha M, Yoon MJ, Cho J, et al. TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell 2009; 138:696 - 708; http://dx.doi.org/10.1016/j.cell.2009.08.002; PMID: 19703396
   PubMed Web of Science ®Google Scholar
• Paroo Z, Ye X, Chen S, Liu Q. Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling. Cell 2009; 139:112 - 22; http://dx.doi.org/10.1016/j.cell.2009.06.044; PMID: 19804757
   PubMed Web of Science ®Google Scholar
• Tang X, Zhang Y, Tucker L, Ramratnam B. Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization. Nucleic Acids Res 2010; 38:6610 - 9; http://dx.doi.org/10.1093/nar/gkq547; PMID: 20554852
   PubMed Web of Science ®Google Scholar
• Chatterjee S, Grosshans H. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 2009; 461:546 - 9; http://dx.doi.org/10.1038/nature08349; PMID: 19734881
   PubMed Web of Science ®Google Scholar
• Das SK, Sokhi UK, Bhutia SK, Azab B, Su ZZ, Sarkar D, et al. Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells. Proc Natl Acad Sci USA 2010; 107:11948 - 53; http://dx.doi.org/10.1073/pnas.0914143107; PMID: 20547861
   PubMed Web of Science ®Google Scholar
• Pawlicki JM, Steitz JA. Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function. Trends Cell Biol 2010; 20:52 - 61; http://dx.doi.org/10.1016/j.tcb.2009.10.004; PMID: 20004579
   PubMed Web of Science ®Google Scholar
• Wagner-Ecker M, Schwager C, Wirkner U, Abdollahi A, Huber PE. MicroRNA expression after ionizing radiation in human endothelial cells. Radiat Oncol 2010; 5:25; http://dx.doi.org/10.1186/1748-717X-5-25; PMID: 20346162
   PubMed Web of Science ®Google Scholar
• Cha HJ, Seong KM, Bae S, Jung JH, Kim CS, Yang KH, et al. Identification of specific microRNAs responding to low and high dose gamma-irradiation in the human lymphoblast line IM9. Oncol Rep 2009; 22:863 - 8; PMID: 19724866
   PubMed Web of Science ®Google Scholar
• Cha HJ, Shin S, Yoo H, Lee EM, Bae S, Yang KH, et al. Identification of ionizing radiation-responsive microRNAs in the IM9 human B lymphoblastic cell line. Int J Oncol 2009; 34:1661 - 8; PMID: 19424585
   PubMed Web of Science ®Google Scholar
• Nikiforova MN, Gandhi M, Kelly L, Nikiforov YE. MicroRNA dysregulation in human thyroid cells following exposure to ionizing radiation. Thyroid 2011; 21:261 - 6; http://dx.doi.org/10.1089/thy.2010.0376; PMID: 21323591
   PubMed Web of Science ®Google Scholar
• Zhang X, Wan G, Berger FG, He X, Lu X. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol Cell 2011; 41:371 - 83; http://dx.doi.org/10.1016/j.molcel.2011.01.020; PMID: 21329876
   PubMed Web of Science ®Google Scholar
• Shin S, Cha HJ, Lee EM, Lee SJ, Seo SK, Jin HO, et al. Alteration of miRNA profiles by ionizing radiation in A549 human non-small cell lung cancer cells. Int J Oncol 2009; 35:81 - 6; PMID: 19513554
   PubMed Web of Science ®Google Scholar
• Shin S, Cha HJ, Lee EM, Jung JH, Lee SJ, Park IC, et al. MicroRNAs are significantly influenced by p53 and radiation in HCT116 human colon carcinoma cells. Int J Oncol 2009; 34:1645 - 52; PMID: 19424583
   PubMed Web of Science ®Google Scholar
• Niemoeller OM, Niyazi M, Corradini S, Zehentmayr F, Li M, Lauber K, et al. MicroRNA expression profiles in human cancer cells after ionizing radiation. Radiat Oncol 2011; 6:29; http://dx.doi.org/10.1186/1748-717X-6-29; PMID: 21453501
   PubMed Web of Science ®Google Scholar
• Weidhaas JB, Babar I, Nallur SM, Trang P, Roush S, Boehm M, et al. MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy. Cancer Res 2007; 67:11111 - 6; http://dx.doi.org/10.1158/0008-5472.CAN-07-2858; PMID: 18056433
   PubMed Web of Science ®Google Scholar
• Li G, Luna C, Qiu J, Epstein DL, Gonzalez P. Alterations in microRNA expression in stress-induced cellular senescence. Mech Ageing Dev 2009; 130:731 - 41; http://dx.doi.org/10.1016/j.mad.2009.09.002; PMID: 19782699
   PubMed Web of Science ®Google Scholar
• Simone NL, Soule BP, Ly D, Saleh AD, Savage JE, Degraff W, et al. Ionizing radiation-induced oxidative stress alters miRNA expression. PLoS One 2009; 4:e6377; http://dx.doi.org/10.1371/journal.pone.0006377; PMID: 19633716
   PubMed Web of Science ®Google Scholar
• Hummel R, Wang T, Watson DI, Michael MZ, Van der Hoek M, Haier J, et al. Chemotherapy-induced modification of microRNA expression in esophageal cancer. Oncol Rep 2011; 26:1011 - 7; PMID: 21743970
   PubMed Web of Science ®Google Scholar
• Wan G, Mathur R, Hu X, Zhang X, Lu X. miRNA response to DNA damage. Trends Biochem Sci 2011; 36:478 - 84; http://dx.doi.org/10.1016/j.tibs.2011.06.002; PMID: 21741842
   PubMed Web of Science ®Google Scholar
• Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, et al. The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature 2009; 459:1010 - 4; http://dx.doi.org/10.1038/nature08025; PMID: 19458619
   PubMed Web of Science ®Google Scholar
• Chehab NH, Malikzay A, Appel M, Halazonetis TD. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes Dev 2000; 14:278 - 88; PMID: 10673500
   PubMed Web of Science ®Google Scholar
• Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, et al. DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 2000; 287:1824 - 7; http://dx.doi.org/10.1126/science.287.5459.1824; PMID: 10710310
   PubMed Web of Science ®Google Scholar
• He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, et al. A microRNA component of the p53 tumour suppressor network. Nature 2007; 447:1130 - 4; http://dx.doi.org/10.1038/nature05939; PMID: 17554337
   PubMed Web of Science ®Google Scholar
• Huang Y, Guerrero-Preston R, Ratovitski EA. Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation. Cell Cycle 2012; 11:1247 - 59; http://dx.doi.org/10.4161/cc.11.6.19670; PMID: 22356768
   PubMed Web of Science ®Google Scholar
• Huang Y, Chuang AY, Ratovitski EA. Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure. Cell Cycle 2011; 10:3938 - 47; http://dx.doi.org/10.4161/cc.10.22.18107; PMID: 22071691
   PubMed Web of Science ®Google Scholar
• Huang Y, Chuang A, Hao H, Talbot C, Sen T, Trink B, et al. Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells. Cell Death Differ 2011; 18:1220 - 30; http://dx.doi.org/10.1038/cdd.2010.188; PMID: 21274007
   PubMed Web of Science ®Google Scholar
• Kawai S, Amano A. BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex. J Cell Biol 2012; 197:201 - 8; http://dx.doi.org/10.1083/jcb.201110008; PMID: 22492723
   PubMed Web of Science ®Google Scholar
• Chaudhry MA, Sachdeva H, Omaruddin RA. Radiation-induced micro-RNA modulation in glioblastoma cells differing in DNA-repair pathways. DNA Cell Biol 2010; 29:553 - 61; http://dx.doi.org/10.1089/dna.2009.0978; PMID: 20380575
   PubMed Web of Science ®Google Scholar
• Tamminga J, Kathiria P, Koturbash I, Kovalchuk O. DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation. Cell Cycle 2008; 7:3731 - 6; http://dx.doi.org/10.4161/cc.7.23.7186; PMID: 19029807
   PubMed Web of Science ®Google Scholar
• Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S. MAPK pathways in radiation responses. Oncogene 2003; 22:5885 - 96; http://dx.doi.org/10.1038/sj.onc.1206701; PMID: 12947395
   PubMed Web of Science ®Google Scholar
• Zeng Y, Sankala H, Zhang X, Graves PR. Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies. Biochem J 2008; 413:429 - 36; http://dx.doi.org/10.1042/BJ20080599; PMID: 18476811
   PubMed Web of Science ®Google Scholar
• Rüdel S, Wang Y, Lenobel R, Körner R, Hsiao HH, Urlaub H, et al. Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Res 2011; 39:2330 - 43; http://dx.doi.org/10.1093/nar/gkq1032; PMID: 21071408
   PubMed Web of Science ®Google Scholar
• Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, et al. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007; 316:1160 - 6; http://dx.doi.org/10.1126/science.1140321; PMID: 17525332
   PubMed Web of Science ®Google Scholar
• Zhang X, Wan G, Mlotshwa S, Vance V, Berger FG, Chen H, et al. Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway. Cancer Res 2010; 70:7176 - 86; http://dx.doi.org/10.1158/0008-5472.CAN-10-0697; PMID: 20668064
   PubMed Web of Science ®Google Scholar
• de Oliveira PE, Zhang L, Wang Z, Lazo JS. Hypoxia-mediated regulation of Cdc25A phosphatase by p21 and miR-21. Cell Cycle 2009; 8:3157 - 64; http://dx.doi.org/10.4161/cc.8.19.9704; PMID: 19738433
   PubMed Web of Science ®Google Scholar
• Bommer GT, Gerin I, Feng Y, Kaczorowski AJ, Kuick R, Love RE, et al. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 2007; 17:1298 - 307; http://dx.doi.org/10.1016/j.cub.2007.06.068; PMID: 17656095
   PubMed Web of Science ®Google Scholar
• Cannell IG, Kong YW, Johnston SJ, Chen ML, Collins HM, Dobbyn HC, et al. p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication. Proc Natl Acad Sci USA 2010; 107:5375 - 80; http://dx.doi.org/10.1073/pnas.0910015107; PMID: 20212154
   PubMed Web of Science ®Google Scholar
• Dong Q, Meng P, Wang T, Qin W, Qin W, Wang F, et al. MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2. PLoS One 2010; 5:e10147; http://dx.doi.org/10.1371/journal.pone.0010147; PMID: 20418948
   PubMed Web of Science ®Google Scholar
• Legesse-Miller A, Elemento O, Pfau SJ, Forman JJ, Tavazoie S, Coller HA. let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts. J Biol Chem 2009; 284:6605 - 9; http://dx.doi.org/10.1074/jbc.C900002200; PMID: 19126550
   PubMed Web of Science ®Google Scholar
• Schultz J, Lorenz P, Gross G, Ibrahim S, Kunz M. MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res 2008; 18:549 - 57; http://dx.doi.org/10.1038/cr.2008.45; PMID: 18379589
   PubMed Web of Science ®Google Scholar
• Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O’Day E, et al. miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to “seedless” 3’UTR microRNA recognition elements. Mol Cell 2009; 35:610 - 25; http://dx.doi.org/10.1016/j.molcel.2009.08.020; PMID: 19748357
   PubMed Web of Science ®Google Scholar
• Li B, Shi XB, Nori D, Chao CK, Chen AM, Valicenti R, et al. Down-regulation of microRNA 106b is involved in p21-mediated cell cycle arrest in response to radiation in prostate cancer cells. Prostate 2011; 71:567 - 74; http://dx.doi.org/10.1002/pros.21272; PMID: 20878953
   PubMed Web of Science ®Google Scholar
• Pickering MT, Stadler BM, Kowalik TF. miR-17 and miR-20a temper an E2F1-induced G1 checkpoint to regulate cell cycle progression. Oncogene 2009; 28:140 - 5; http://dx.doi.org/10.1038/onc.2008.372; PMID: 18836483
   PubMed Web of Science ®Google Scholar
• Cloonan N, Brown MK, Steptoe AL, Wani S, Chan WL, Forrest AR, et al. The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition. Genome Biol 2008; 9:R127; http://dx.doi.org/10.1186/gb-2008-9-8-r127; PMID: 18700987
   PubMed Web of Science ®Google Scholar
• Ng WL, Yan D, Zhang X, Mo YY, Wang Y. Over-expression of miR-100 is responsible for the low-expression of ATM in the human glioma cell line: M059J. DNA Repair (Amst) 2010; 9:1170 - 5; http://dx.doi.org/10.1016/j.dnarep.2010.08.007; PMID: 20869334
   PubMed Web of Science ®Google Scholar
• Hu H, Du L, Nagabayashi G, Seeger RC, Gatti RA. ATM is down-regulated by N-Myc-regulated microRNA-421. Proc Natl Acad Sci USA 2010; 107:1506 - 11; http://dx.doi.org/10.1073/pnas.0907763107; PMID: 20080624
   PubMed Web of Science ®Google Scholar
• Yan D, Ng WL, Zhang X, Wang P, Zhang Z, Mo YY, et al. Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS One 2010; 5:e11397; http://dx.doi.org/10.1371/journal.pone.0011397; PMID: 20617180
   PubMed Web of Science ®Google Scholar
• Garcia AI, Buisson M, Bertrand P, Rimokh R, Rouleau E, Lopez BS, et al. Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. EMBO Mol Med 2011; 3:279 - 90; http://dx.doi.org/10.1002/emmm.201100136; PMID: 21472990
   PubMed Web of Science ®Google Scholar
• Valeri N, Gasparini P, Fabbri M, Braconi C, Veronese A, Lovat F, et al. Modulation of mismatch repair and genomic stability by miR-155. Proc Natl Acad Sci USA 2010; 107:6982 - 7; http://dx.doi.org/10.1073/pnas.1002472107; PMID: 20351277
   PubMed Web of Science ®Google Scholar
• Mao G, Lee S, Ortega J, Gu L, Li GM. Modulation of microRNA processing by mismatch repair protein MutLα. Cell Res 2012; 22:973 - 85; http://dx.doi.org/10.1038/cr.2012.18; PMID: 22290424
   PubMed Web of Science ®Google Scholar
• Martello G, Rosato A, Ferrari F, Manfrin A, Cordenonsi M, Dupont S, et al. A MicroRNA targeting dicer for metastasis control. Cell 2010; 141:1195 - 207; http://dx.doi.org/10.1016/j.cell.2010.05.017; PMID: 20603000
   PubMed Web of Science ®Google Scholar
• Forman JJ, Legesse-Miller A, Coller HA. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc Natl Acad Sci USA 2008; 105:14879 - 84; http://dx.doi.org/10.1073/pnas.0803230105; PMID: 18812516
   PubMed Web of Science ®Google Scholar
• Jakymiw A, Patel RS, Deming N, Bhattacharyya I, Shah P, Lamont RJ, et al. Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells. Genes Chromosomes Cancer 2010; 49:549 - 59; http://dx.doi.org/10.1002/gcc.20765; PMID: 20232482
   PubMed Web of Science ®Google Scholar
• Tokumaru S, Suzuki M, Yamada H, Nagino M, Takahashi T. let-7 regulates Dicer expression and constitutes a negative feedback loop. Carcinogenesis 2008; 29:2073 - 7; http://dx.doi.org/10.1093/carcin/bgn187; PMID: 18700235
   PubMed Web of Science ®Google Scholar
• Glorian V, Maillot G, Polès S, Iacovoni JS, Favre G, Vagner S. HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis. Cell Death Differ 2011; 18:1692 - 701; http://dx.doi.org/10.1038/cdd.2011.35; PMID: 21527938
   PubMed Web of Science ®Google Scholar
• Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, et al. Site-specific DICER and DROSHA RNA products control the DNA-damage response. Nature 2012; 488:231 - 5; http://dx.doi.org/10.1038/nature11179; PMID: 22722852
   PubMed Web of Science ®Google Scholar
• Josson S, Sung SY, Lao K, Chung LW, Johnstone PA. Radiation modulation of microRNA in prostate cancer cell lines. Prostate 2008; 68:1599 - 606; http://dx.doi.org/10.1002/pros.20827; PMID: 18668526
   PubMed Web of Science ®Google Scholar
• Akao Y, Noguchi S, Iio A, Kojima K, Takagi T, Naoe T. Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells. Cancer Lett 2011; 300:197 - 204; http://dx.doi.org/10.1016/j.canlet.2010.10.006; PMID: 21067862
   PubMed Web of Science ®Google Scholar
• Yu Y, Wang Y, Ren X, Tsuyada A, Li A, Liu LJ, et al. Context-dependent bidirectional regulation of the MutS homolog 2 by transforming growth factor β contributes to chemoresistance in breast cancer cells. Mol Cancer Res 2010; 8:1633 - 42; http://dx.doi.org/10.1158/1541-7786.MCR-10-0362; PMID: 21047769
   PubMed Web of Science ®Google Scholar
• Valeri N, Gasparini P, Braconi C, Paone A, Lovat F, Fabbri M, et al. MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2). Proc Natl Acad Sci USA 2010; 107:21098 - 103; http://dx.doi.org/10.1073/pnas.1015541107; PMID: 21078976
   PubMed Web of Science ®Google Scholar
• Zhang J, Sun Q, Zhang Z, Ge S, Han ZG, Chen WT. Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. Oncogene 2012; In press http://dx.doi.org/10.1038/onc.2012.28; PMID: 22330136
   PubMed Web of Science ®Google Scholar
• Hicks JK, Chute CL, Paulsen MT, Ragland RL, Howlett NG, Guéranger Q, et al. Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links. Mol Cell Biol 2010; 30:1217 - 30; http://dx.doi.org/10.1128/MCB.00993-09; PMID: 20028736
   PubMed Web of Science ®Google Scholar
• Ando Y, Maida Y, Morinaga A, Burroughs AM, Kimura R, Chiba J, et al. Two-step cleavage of hairpin RNA with 5′ overhangs by human DICER. BMC Mol Biol 2011; 12:6; http://dx.doi.org/10.1186/1471-2199-12-6; PMID: 21306637
   PubMed Web of Science ®Google Scholar
• Ebert MS, Sharp PA. MicroRNA sponges: progress and possibilities. RNA 2010; 16:2043 - 50; http://dx.doi.org/10.1261/rna.2414110; PMID: 20855538
   PubMed Web of Science ®Google Scholar
• Choi WY, Giraldez AJ, Schier AF. Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science 2007; 318:271 - 4; http://dx.doi.org/10.1126/science.1147535; PMID: 17761850
   PubMed Web of Science ®Google Scholar
• Esquela-Kerscher A, Trang P, Wiggins JF, Patrawala L, Cheng A, Ford L, et al. The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle 2008; 7:759 - 64; http://dx.doi.org/10.4161/cc.7.6.5834; PMID: 18344688
   PubMed Web of Science ®Google Scholar
• Kota J, Chivukula RR, O’Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009; 137:1005 - 17; http://dx.doi.org/10.1016/j.cell.2009.04.021; PMID: 19524505
   PubMed Web of Science ®Google Scholar
• Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 2004; 117:927 - 39; http://dx.doi.org/10.1016/j.cell.2004.06.006; PMID: 15210113
   PubMed Web of Science ®Google Scholar
• Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG, et al. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat Biotechnol 2010; 28:341 - 7; http://dx.doi.org/10.1038/nbt.1618; PMID: 20351690
   PubMed Web of Science ®Google Scholar
• Takeshita F, Minakuchi Y, Nagahara S, Honma K, Sasaki H, Hirai K, et al. Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci USA 2005; 102:12177 - 82; http://dx.doi.org/10.1073/pnas.0501753102; PMID: 16091473
   PubMed Web of Science ®Google Scholar
• Melo SA, Kalluri R. Molecular pathways: microRNAs as cancer therapeutics. Clin Cancer Res 2012; 18:4234 - 9; http://dx.doi.org/10.1158/1078-0432.CCR-11-2010; PMID: 22711704
   PubMed Web of Science ®Google Scholar
• Bader AG, Brown D, Stoudemire J, Lammers P. Developing therapeutic microRNAs for cancer. Gene Ther 2011; 18:1121 - 6; http://dx.doi.org/10.1038/gt.2011.79; PMID: 21633392
   PubMed Web of Science ®Google Scholar
• Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, et al. Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat Nanotechnol 2012; 7:389 - 93; http://dx.doi.org/10.1038/nnano.2012.73; PMID: 22659608
   PubMed Web of Science ®Google Scholar
• Arima H, Yoshimatsu A, Ikeda H, Ohyama A, Motoyama K, Higashi T, et al. Folate-PEG-appended dendrimer conjugate with α-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier. Mol Pharm 2012; 9:2591 - 604; http://dx.doi.org/10.1021/mp300188f; PMID: 22873579
   PubMed Web of Science ®Google Scholar
• Pothof J, Verkaik NS, Hoeijmakers JH, van Gent DC. MicroRNA responses and stress granule formation modulate the DNA damage response. Cell Cycle 2009; 8:3462 - 8; http://dx.doi.org/10.4161/cc.8.21.9835; PMID: 19823042
   PubMed Web of Science ®Google Scholar
• Chen X, Liang H, Zhang J, Zen K, Zhang CY. Secreted microRNAs: a new form of intercellular communication. Trends Cell Biol 2012; 22:125 - 32; http://dx.doi.org/10.1016/j.tcb.2011.12.001; PMID: 22260888
   PubMed Web of Science ®Google Scholar
• Cui W, Ma J, Wang Y, Biswal S. Plasma miRNA as biomarkers for assessment of total-body radiation exposure dosimetry. PLoS One 2011; 6:e22988; http://dx.doi.org/10.1371/journal.pone.0022988; PMID: 21857976
   PubMed Web of Science ®Google Scholar
• Templin T, Paul S, Amundson SA, Young EF, Barker CA, Wolden SL, et al. Radiation-induced micro-RNA expression changes in peripheral blood cells of radiotherapy patients. Int J Radiat Oncol Biol Phys 2011; 80:549 - 57; http://dx.doi.org/10.1016/j.ijrobp.2010.12.061; PMID: 21420249
   PubMed Web of Science ®Google Scholar
• Templin T, Amundson SA, Brenner DJ, Smilenov LB. Whole mouse blood microRNA as biomarkers for exposure to γ-rays and (56)Fe ion. Int J Radiat Biol 2011; 87:653 - 62; http://dx.doi.org/10.3109/09553002.2010.549537; PMID: 21271940
   PubMed Web of Science ®Google Scholar
• Crosby ME, Kulshreshtha R, Ivan M, Glazer PM. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res 2009; 69:1221 - 9; http://dx.doi.org/10.1158/0008-5472.CAN-08-2516; PMID: 19141645
   PubMed Web of Science ®Google Scholar
• Zhang S, Chen H, Zhao X, Cao J, Tong J, Lu J, et al. REV3L 3′UTR 460 T>C polymorphism in microRNA target sites contributes to lung cancer susceptibility. Oncogene 2012; in press http://dx.doi.org/10.1038/onc.2012.32
   Web of Science ®Google Scholar
• Tsai YS, Lin CS, Chiang SL, Lee CH, Lee KW, Ko YC. Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG. Toxicol Sci 2011; 123:480 - 90; http://dx.doi.org/10.1093/toxsci/kfr182; PMID: 21750350
   PubMed Web of Science ®Google Scholar
• Le MT, Teh C, Shyh-Chang N, Xie H, Zhou B, Korzh V, et al. MicroRNA-125b is a novel negative regulator of p53. Genes Dev 2009; 23:862 - 76; http://dx.doi.org/10.1101/gad.1767609; PMID: 19293287
   PubMed Web of Science ®Google Scholar
• Hu W, Chan CS, Wu R, Zhang C, Sun Y, Song JS, et al. Negative regulation of tumor suppressor p53 by microRNA miR-504. Mol Cell 2010; 38:689 - 99; http://dx.doi.org/10.1016/j.molcel.2010.05.027; PMID: 20542001
   PubMed Web of Science ®Google Scholar
• Kumar M, Lu Z, Takwi AA, Chen W, Callander NS, Ramos KS, et al. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene 2011; 30:843 - 53; http://dx.doi.org/10.1038/onc.2010.457; PMID: 20935678
   PubMed Web of Science ®Google Scholar
• Butz H, Likó I, Czirják S, Igaz P, Khan MM, Zivkovic V, et al. Down-regulation of Wee1 kinase by a specific subset of microRNA in human sporadic pituitary adenomas. J Clin Endocrinol Metab 2010; 95:E181 - 91; http://dx.doi.org/10.1210/jc.2010-0581; PMID: 20668041
   PubMed Web of Science ®Google Scholar
• He JF, Luo YM, Wan XH, Jiang D. Biogenesis of MiRNA-195 and its role in biogenesis, the cell cycle, and apoptosis. J Biochem Mol Toxicol 2011; 25:404 - 8; http://dx.doi.org/10.1002/jbt.20396; PMID: 22190509
   PubMed Web of Science ®Google Scholar
• Sarkar S, Dey BK, Dutta A. MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A. Mol Biol Cell 2010; 21:2138 - 49; http://dx.doi.org/10.1091/mbc.E10-01-0062; PMID: 20462953
   PubMed Web of Science ®Google Scholar
• Yang X, Feng M, Jiang X, Wu Z, Li Z, Aau M, et al. miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A. Genes Dev 2009; 23:2388 - 93; http://dx.doi.org/10.1101/gad.1819009; PMID: 19833767
   PubMed Web of Science ®Google Scholar
• Kim HH, Kuwano Y, Srikantan S, Lee EK, Martindale JL, Gorospe M. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev 2009; 23:1743 - 8; http://dx.doi.org/10.1101/gad.1812509; PMID: 19574298
   PubMed Web of Science ®Google Scholar
• Sachdeva M, Zhu S, Wu F, Wu H, Walia V, Kumar S, et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 2009; 106:3207 - 12; http://dx.doi.org/10.1073/pnas.0808042106; PMID: 19202062
   PubMed Web of Science ®Google Scholar
• Wong P, Iwasaki M, Somervaille TC, Ficara F, Carico C, Arnold C, et al. The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression. Cancer Res 2010; 70:3833 - 42; http://dx.doi.org/10.1158/0008-5472.CAN-09-3268; PMID: 20406979
   PubMed Web of Science ®Google Scholar
• le Sage C, Nagel R, Egan DA, Schrier M, Mesman E, Mangiola A, et al. Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J 2007; 26:3699 - 708; http://dx.doi.org/10.1038/sj.emboj.7601790; PMID: 17627278
   PubMed Web of Science ®Google Scholar
• Tian RQ, Wang XH, Hou LJ, Jia WH, Yang Q, Li YX, et al. MicroRNA-372 is down-regulated and targets cyclin-dependent kinase 2 (CDK2) and cyclin A1 in human cervical cancer, which may contribute to tumorigenesis. J Biol Chem 2011; 286:25556 - 63; http://dx.doi.org/10.1074/jbc.M111.221564; PMID: 21646351
   PubMed Web of Science ®Google Scholar
• Afanasyeva EA, Mestdagh P, Kumps C, Vandesompele J, Ehemann V, Theissen J, et al. MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. Cell Death Differ 2011; 18:974 - 84; http://dx.doi.org/10.1038/cdd.2010.164; PMID: 21233845
   PubMed Web of Science ®Google Scholar
• Lin SL, Chang DC, Ying SY, Leu D, Wu DT. MicroRNA miR-302 inhibits the tumorigenecity of human pluripotent stem cells by coordinate suppression of the CDK2 and CDK4/6 cell cycle pathways. Cancer Res 2010; 70:9473 - 82; http://dx.doi.org/10.1158/0008-5472.CAN-10-2746; PMID: 21062975
   PubMed Web of Science ®Google Scholar