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Cell Cycle Volume 12, 2013 - Issue 13
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Editorials: Cell Cycle Features

An unexpected role for PI4,5P2 in EGF receptor endosomal trafficking

Yue Sun University of Wisconsin-Madison School of Medicine and Public Health; Madison, WI USA
,
Andrew C. Hedman Program in Molecular and Cellular Pharmacology; University of Wisconsin-Madison School of Medicine and Public Health; Madison, WI USA
,
Xiaojun Tan Program in Molecular and Cellular Pharmacology; University of Wisconsin-Madison School of Medicine and Public Health; Madison, WI USA
&
Richard A. Anderson University of Wisconsin-Madison School of Medicine and Public Health; Madison, WI USA; Program in Molecular and Cellular Pharmacology; University of Wisconsin-Madison School of Medicine and Public Health; Madison, WI USACorrespondence[email protected]
Pages 1991-1992 | Received 27 May 2013, Accepted 31 May 2013, Published online: 10 Jun 2013

References

  • Arteaga CL. Epidermal growth factor receptor dependence in human tumors: more than just expression?. Oncologist 2002; 7:Suppl 4 31 - 9; http://dx.doi.org/10.1634/theoncologist.7-suppl_4-31; PMID: 12202786
  • Barbieri MA, Heath CM, Peters EM, Wells A, Davis JN, Stahl PD. Phosphatidylinositol-4-phosphate 5-kinase-1beta is essential for epidermal growth factor receptor-mediated endocytosis. J Biol Chem 2001; 276:47212 - 6; http://dx.doi.org/10.1074/jbc.C100490200; PMID: 11581249
  • Petiot A, Faure J, Stenmark H, Gruenberg J. PI3P signaling regulates receptor sorting but not transport in the endosomal pathway. J Cell Biol 2003; 162:971 - 9; http://dx.doi.org/10.1083/jcb.200303018; PMID: 12975344
  • Di Paolo G, De Camilli P. Phosphoinositides in cell regulation and membrane dynamics. Nature 2006; 443:651 - 7; http://dx.doi.org/10.1038/nature05185; PMID: 17035995
  • Sun Y, Hedman AC, Tan X, Schill NJ, Anderson RA. Endosomal Type Iγ PIP 5-Kinase Controls EGF Receptor Lysosomal Sorting. Dev Cell 2013; 25:144 - 55; http://dx.doi.org/10.1016/j.devcel.2013.03.010; PMID: 23602387
  • Doughman RL, Firestone AJ, Anderson RA. Phosphatidylinositol phosphate kinases put PI4,5P(2) in its place. J Membr Biol 2003; 194:77 - 89; http://dx.doi.org/10.1007/s00232-003-2027-7; PMID: 14502432
  • Sun Y, Thapa N, Hedman AC, Anderson RA. Phosphatidylinositol 4,5-bisphosphate: Targeted production and signaling. Bioessays 2013; 35:513 - 22; http://dx.doi.org/10.1002/bies.201200171; PMID: 23575577
  • Seshacharyulu P, Ponnusamy MP, Haridas D, Jain M, Ganti AK, Batra SK. Targeting the EGFR signaling pathway in cancer therapy. Expert Opin Ther Targets 2012; 16:15 - 31; http://dx.doi.org/10.1517/14728222.2011.648617; PMID: 22239438

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