780
Views
45
CrossRef citations to date
0
Altmetric
Perspective

Long antisense non-coding RNAs and their role in transcription and oncogenesis

&
Pages 2544-2547 | Published online: 01 Jul 2010

References

  • Finocchiaro G, Carro MS, Francois S, Parise P, DiNinni V, Muller H. Localizing hotspots of antisense transcription. Nucleic Acids Res 2007; 35:1488 - 1500
  • He Y, Vogelstein B, Velculescu VE, Papadopoulos N, Kinzler KW. The antisense transcriptomes of human cells. Science 2008; 322:1855 - 1857
  • Osato N, Suzuki Y, Ikeo K, Gojobori T. Transcriptional interferences in cis natural antisense transcripts of humans and mice. Genetics 2007; 176:1299 - 1306
  • Yelin R, Dahary D, Sorek R, Levanon EY, Goldstein O, Shoshan A, et al. Widespread occurrence of antisense transcription in the human genome. Nat Biotechnol 2003; 21:379 - 386
  • Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, et al. Antisense transcription in the mammalian transcriptome. Science 2005; 309:1564 - 1566
  • Rosok O, Sioud M. Systematic identification of sense-antisense transcripts in mammalian cells. Nat Biotechnol 2004; 22:104 - 108
  • Conley AB, Miller WJ, Jordan IK. Human cis natural antisense transcripts initiated by transposable elements. Trends Genet 2008; 24:53 - 56
  • Furuno M, Pang KC, Ninomiya N, Fukuda S, Frith MC, Bult C, et al. Clusters of internally primed transcripts reveal novel long noncoding RNAs. PLoS Genet 2006; 2:37
  • Kiyosawa H, Mise N, Iwase S, Hayashizaki Y, Abe K. Disclosing hidden transcripts: mouse natural sense-antisense transcripts tend to be poly(A) negative and nuclear localized. Genome Res 2005; 15:463 - 474
  • Khalil AM, Guttman M, Huarte M, Garber M, Raj A, Rivea Morales D, et al. Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci USA 2009; 106:11667 - 11672
  • Kapranov P, Cheng J, Dike S, Nix DA, Duttagupta R, Willingham AT, et al. RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science 2007; 316:1484 - 1488
  • Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, et al. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 2009; 458:223 - 227
  • Cheng J, Kapranov P, Drenkow J, Dike S, Brubaker S, Patel S, et al. Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. Science 2005; 308:1149 - 1154
  • Babak T, Blencowe BJ, Hughes TR. A systematic search for new mammalian noncoding RNAs indicates little conserved intergenic transcription. BMC Genomics 2005; 6:104
  • Taft RJ, Pheasant M, Mattick JS. The relationship between non-protein-coding DNA and eukaryotic complexity. Bioessays 2007; 29:288 - 299
  • Stolt P, Zillig W. Antisense RNA mediates transcriptional processing in an archaebacterium, indicating a novel kind of RNase activity. Mol Microbiol 1993; 7:875 - 882
  • Knee R, Murphy PR. Regulation of gene expression by natural antisense RNA transcripts. Neurochem Int 1997; 31:379 - 392
  • Izant JG, Weintraub H. Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA. Science 1985; 229:345 - 352
  • Tsanev R, Sendov B. An epigenetic mechanism for carcinogenesis. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol 1971; 76:299 - 319
  • Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature 2004; 429:457 - 463
  • Kouzarides T. Chromatin modifications and their function. Cell 2007; 128:693 - 705
  • Morris KV. Non-coding RNAs, epigenetic memory and the passage of information to progeny. RNA Biol 2009; 6:242 - 247
  • Matzke MA, Primig M, Trnovsky J, Matzke AJ. Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants. EMBO J 1989; 8:643 - 649
  • Morris KV, Chan SW, Jacobsen SE, Looney DJ. Small interfering RNA-induced transcriptional gene silencing in human cells. Science 2004; 305:1289 - 1292
  • Hawkins PG, Morris KV. RNA and transcriptional modulation of gene expression. Cell Cycle 2008; 7:602 - 607
  • Morris KV. RNA-directed transcriptional gene silencing and activation in human cells. Oligonucleotides 2009; 19:299 - 306
  • Weinberg MS, Villeneuve LM, Ehsani A, Amarzguioui M, Aagaard L, Chen ZX, et al. The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. RNA 2006; 12:256 - 262
  • Latos PA, Barlow DP. Regulation of imprinted expression by macro non-coding RNAs. RNA Biol 2009; 6:100 - 106
  • Zaratiegui M, Irvine DV, Martienssen RA. Noncoding RNAs and gene silencing. Cell 2007; 128:763 - 776
  • Lee JT. Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome. Genes Dev 2009; 23:1831 - 1842
  • Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP, et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature 2008; 451:202 - 206
  • Morris KV, Santoso S, Turner AM, Pastori C, Hawkins PG. Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet 2008; 4:1000258
  • Morris KV. Long antisense non-coding RNAs function to direct epigenetic complexes that regulate transcription in human cells. Epigenetics 2009; 4:296 - 301
  • Camblong J, Iglesias N, Fickentscher C, Dieppois G, Stutz F. Antisense RNA stabilization induces transcriptional gene silencing via histone deacetylation in S. cerevisiae. Cell 2007; 131:706 - 717
  • Camblong J, Beyrouthy N, Guffanti E, Schlaepfer G, Steinmetz LM, Stutz F. Trans-acting antisense RNAs mediate transcriptional gene cosuppression in S. cerevisiae. Genes Dev 2009; 23:1534 - 1545
  • Guell M, van Noort V, Yus E, Chen WH, Leigh-Bell J, Michalodimitrakis K, et al. Transcriptome complexity in a genome-reduced bacterium. Science 2009; 326:1268 - 1271
  • Swiezewski S, Liu F, Magusin A, Dean C. Cold-induced silencing by long antisense transcripts of an Arabidopsis Polycomb target. Nature 2009; 462:799 - 802
  • Mahmoudi S, Henriksson S, Corcoran M, Mendez-Vidal C, Wiman KG, Farnebo M. Wrap53, a natural p53 antisense transcript required for p53 induction upon DNA damage. Mol Cell 2009; 33:462 - 471
  • Celano P, Berchtold CM, Kizer DL, Weeraratna A, Nelkin BD, Baylin SB, et al. Characterization of an endogenous RNA transcript with homology to the antisense strand of the human c-myc gene. J Biol Chem 1992; 267:15092 - 15096
  • Li K, Blum Y, Verma A, Liu Z, Pramanik K, Leigh NR, et al. A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo. Blood 2010; 115:133 - 139
  • Ebralidze AK, Guibal FC, Steidl U, Zhang P, Lee S, Bartholdy B, et al. PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element. Genes Dev 2008; 22:2085 - 2092
  • Cortez CC, Jones PA. Chromatin, cancer and drug therapies. Mutat Res 2008; 647:44 - 51
  • Khraiwesh B, Arif MA, Seumel GI, Ossowski S, Weigel D, Reski R, et al. Transcriptional control of gene expression by microRNAs. Cell 2010; 140:111 - 122
  • Taft RJ, Glazov EA, Cloonan N, Simons C, Stephen S, Faulkner GJ, et al. Tiny RNAs associated with transcription start sites in animals. Nat Genet 2009; 41:572 - 578
  • Taft RJ, Kaplan CD, Simons C, Mattick JS. Evolution, biogenesis and function of promoter-associated RNAs. Cell Cycle 2009; 8:2332 - 2338
  • Tomkins GM, Gelehrter TD, Granner D, Martin DJr, Samuels HH, Thompson EB. Control of specific gene expression in higher organisms. Expression of mammalian genes may be controlled by repressors acting on the translation of messenger RNA. Science 1969; 166:1474 - 1480
  • Chiba M, Kiyosawa H, Hiraiwa N, Ohkohchi N, Yasue H. Existence of Pink1 antisense RNAs in mouse and their localization. Cytogenet Genome Res 2009; 126:259 - 270
  • Chiba M, Kubo M, Miura T, Sato T, Rezaeian AH, Kiyosawa H, et al. Localization of sense and antisense transcripts of Prdx2 gene in mouse tissues. Cytogenet Genome Res 2008; 121:222 - 231
  • Spicer DB, Sonenshein GE. An antisense promoter of the murine c-myc gene is localized within intron 2. Mol Cell Biol 1992; 12:1324 - 1329
  • Han J, Kim D, Morris KV. Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells. Proc Natl Acad Sci USA 2007; 104:12422 - 12427

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.