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Parole terms for a killer

Directing the caspase3/CAD induced DNA strand breaks to coordinate changes in gene expression

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Pages 3012-3017 | Published online: 01 Aug 2010

References

  • Jung D, Alt FW. Unraveling V(D)J recombination; insights into gene regulation. Cell 2004; 116:299 - 311
  • Li W, Ma H. Double-stranded DNA breaks and gene functions in recombination and meiosis. Cell Res 2006; 16:402 - 412
  • Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, Glass CK, et al. A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science 2006; 312:1798 - 1802
  • Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, et al. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell 2009; 139:1069 - 1083
  • Larsen BD, Rampalli S, Burns LE, Brunette S, Dilworth FJ, Megeney LA. Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks. Proc Natl Acad Sci USA 2010; 107:4230 - 4235
  • Fischer U, Janicke RU, Schulze-Osthoff K. Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ 2003; 10:76 - 100
  • Widlak P, Garrard WT. Roles of the major apoptotic nuclease-DNA fragmentation factor-in biology and disease. Cell Mol Life Sci 2009; 66:263 - 274
  • Samejima K, Earnshaw WC. Trashing the genome: the role of nucleases during apoptosis. Nat Rev Mol Cell Biol 2005; 6:677 - 688
  • Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, Walk SF, et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 2009; 461:282 - 286
  • Radic M, Marion T, Monestier M. Nucleosomes are exposed at the cell surface in apoptosis. J Immunol 2004; 172:6692 - 6700
  • McCarty JS, Toh SY, Li P. Study of DFF45 in its role of chaperone and inhibitor: Two independent inhibitory domains of DFF40 nuclease activity. Biochem Biophys Res Commun 1999; 264:176 - 180
  • Sakahira H, Nagata S. Co-translational folding of caspase-activated DNase with Hsp70, Hsp40 and inhibitor of caspase-activated DNase. J Biol Chem 2002; 277:3364 - 3370
  • Lechardeur D, Xu M, Lukacs GL. Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells. J Cell Biol 2004; 167:851 - 862
  • Korn C, Scholz SR, Gimadutdinow O, Lurz R, Pingoud A, Meiss G. Interaction of DNA fragmentation factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state. J Biol Chem 2005; 280:6005 - 6015
  • Reh S, Korn C, Gimadutdinow O, Meiss G. Structural basis for stable DNA complex formation by the caspase-activated DNase. J Biol Chem 2005; 280:41707 - 41715
  • Woo EJ, Kim YG, Kim MS, Han WD, Shin S, Robinson H, et al. Structural mechanism for inactivation and activation of CAD/DFF40 in the apoptotic pathway. Mol Cell 2004; 14:531 - 539
  • Abdul-Ghani M, Megeney LA. Rehabilitation of a contract killer: caspase-3 directs stem cell differentiation. Cell Stem Cell 2008; 2:515 - 516
  • Fernando P, Megeney LA. Is caspase-dependent apoptosis only cell differentiation taken to the extreme?. FASEB J 2007; 21:8 - 17
  • Zeuner A, Eramo A, Testa U, Felli N, Pelosi E, Mariani G, et al. Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1. Cell Death Differ 2003; 10:905 - 913
  • Fujita J, Crane AM, Souza MK, Dejosez M, Kyba M, Flavell RA, et al. Caspase activity mediates the differentiation of embryonic stem cells. Cell Stem Cell 2008; 2:595 - 601
  • Fernando P, Brunette S, Megeney LA. Neural stem cell differentiation is dependent upon endogenous caspase 3 activity. FASEB J 2005; 19:1671 - 1673
  • Fernando P, Kelly JF, Balazsi K, Slack RS, Megeney LA. Caspase 3 activity is required for skeletal muscle differentiation. Proc Natl Acad Sci USA 2002; 99:11025 - 11030
  • Kanuka H, Kuranaga E, Takemoto K, Hiratou T, Okano H, Miura M. Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development. EMBO J 2005; 24:3793 - 3806
  • Cheung WL, Ajiro K, Samejima K, Kloc M, Cheung P, Mizzen CA, et al. Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 2003; 113:507 - 517
  • Ahn SH, Cheung WL, Hsu JY, Diaz RL, Smith MM, Allis CD. Sterile 20 kinase phosphorylates histone H2B at serine 10 during hydrogen peroxide-induced apoptosis in S. cerevisiae. Cell 2005; 120:25 - 36
  • Graves JD, Gotoh Y, Draves KE, Ambrose D, Han DK, Wright M, et al. Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1. EMBO J 1998; 17:2224 - 2234
  • Zeng Q, Hong W. The emerging role of the hippo pathway in cell contact inhibition, organ size control and cancer development in mammals. Cancer Cell 2008; 13:188 - 192
  • Sun Y, Wang T, Su Y, Yin Y, Xu S, Ma C, et al. The behavior of SATB1, a MAR-binding protein, in response to apoptosis stimulation. Cell Biol Int 2006; 30:244 - 247
  • Gotzmann J, Meissner M, Gerner C. The fate of the nuclear matrix-associated-region-binding protein SATB1 during apoptosis. Cell Death Differ 2000; 7:425 - 438
  • Tan JA, Sun Y, Song J, Chen Y, Krontiris TG, Durrin LK. SUMO conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavage. J Biol Chem 2008; 283:18124 - 18134
  • Liu QY, Ribecco-Lutkiewicz M, Carson C, Testolin L, Bergeron D, Kohwi-Shigematsu T, et al. Mapping the initial DNA breaks in apoptotic Jurkat cells using ligation-mediated PCR. Cell Death Differ 2003; 10:278 - 289
  • Widlak P, Kalinowska M, Parseghian MH, Lu X, Hansen JC, Garrard WT. The histone H1 C-terminal domain binds to the apoptotic nuclease, DNA fragmentation factor (DFF40/CAD) and stimulates DNA cleavage. Biochemistry 2005; 44:7871 - 7878
  • Ninios YP, Sekeri-Pataryas KE, Sourlingas TG. Histone H1 subtype preferences of DFF40 and possible nuclear localization of DFF40/45 in normal and trichostatin A-treated NB4 leukemic cells. Apoptosis 2010; 15:128 - 138
  • Izzo A, Kamieniarz K, Schneider R. The histone H1 family: specific members, specific functions?. Biol Chem 2008; 389:333 - 343
  • Lee H, Habas R, Abate-Shen C. MSX1 cooperates with histone H1b for inhibition of transcription and myogenesis. Science 2004; 304:1675 - 1678
  • Odelberg SJ, Kollhoff A, Keating MT. Dedifferentiation of mammalian myotubes induced by msx1. Cell 2000; 103:1099 - 1109
  • Hunter AL, Zhang J, Chen SC, Si X, Wong B, Ekhterae D, et al. Apoptosis repressor with caspase recruitment domain (ARC) inhibits myogenic differentiation. FEBS Lett 2007; 581:879 - 884
  • Murray TV, McMahon JM, Howley BA, Stanley A, Ritter T, Mohr A, et al. A non-apoptotic role for caspase-9 in muscle differentiation. J Cell Sci 2008; 121:3786 - 3793
  • Koto A, Kuranaga E, Miura M. Temporal regulation of Drosophila IAP1 determines caspase functions in sensory organ development. J Cell Biol 2009; 187:219 - 231
  • West JD, Ji C, Marnett LJ. Modulation of DNA fragmentation factor 40 nuclease activity by poly(ADP-ribose) polymerase-1. J Biol Chem 2005; 280:15141 - 15147
  • Farzaneh F, Shall S, Johnstone AP. The dynamic nature of DNA-strand breaks present in differentiating muscle cells and quiescent lymphocytes. FEBS Lett 1985; 189:62 - 66
  • Ahn JY, Liu X, Cheng D, Peng J, Chan PK, Wade PA, et al. Nucleophosmin/B23, a nuclear PI(3,4,5)P(3) receptor, mediates the antiapoptotic actions of NGF by inhibiting CAD. Mol Cell 2005; 18:435 - 445
  • Ahn JY, Liu X, Liu Z, Pereira L, Cheng D, Peng J, et al. Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. EMBO J 2006; 25:2083 - 2095
  • Ju BG, Rosenfeld MG. A breaking strategy for topoisomerase IIbeta/PARP-1-dependent regulated transcription. Cell Cycle 2006; 5:2557 - 2560
  • Durrieu F, Samejima K, Fortune JM, Kandels-Lewis S, Osheroff N, Earnshaw WC. DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution. Curr Biol 2000; 10:923 - 926
  • Popp C, Dean W, Feng S, Cokus SJ, Andrews S, Pellegrini M, et al. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010; 463:1101 - 1105
  • Bhutani N, Brady JJ, Damian M, Sacco A, Corbel SY, Blau HM. Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 2010; 463:1042 - 1047
  • Petersen-Mahrt SK, Harris RS, Neuberger MS. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 2002; 418:99 - 103
  • Jost JP, Oakeley EJ, Zhu B, Benjamin D, Thiry S, Siegmann M, et al. 5-Methylcytosine DNA glycosylase participates in the genome-wide loss of DNA methylation occurring during mouse myoblast differentiation. Nucleic Acids Res 2001; 29:4452 - 4461

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