RAF associates with phosphorylated nuclear BubR1 during endoreduplication induced by JAK inhibition

References

• Yamaoka K, Saharinen P, Pesu M, Holt VE 3rd, Silvennoinen O, O'Shea JJ. The Janus kinases (JAKs). Genome Biol 2004; 5:253
   PubMed Web of Science ®Google Scholar
• Benekli M, Baer MR, Baumann H, Wetzler M. Signal transducer and activator of transcription proteins in leukemias. Blood 2003; 101:2940 - 2944
   PubMed Web of Science ®Google Scholar
• Reiterer G, Yen A. Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication. Cancer Res 2006; 66:9083 - 9089
   PubMed Web of Science ®Google Scholar
• David M, Petricoin E 3rd, Benjamin C, Pine R, Weber MJ, Larner AC. Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins. Science 1995; 269:1721 - 1723
   PubMed Web of Science ®Google Scholar
• Caraglia M, Vitale G, Marra M, Budillon A, Tagliaferri P, Abbruzzese A. Alpha-interferon and its effects on signalling pathways within cells. Curr Protein Pept Sci 2004; 5:475 - 485
   PubMed Web of Science ®Google Scholar
• Pircher TJ, Petersen H, Gustafsson JA, Haldosen LA. Extracellular signal-regulated kinase (ERK) interacts with signal transducer and activator of transcription (STAT) 5a. Mol Endocrinol 1999; 13:555 - 565
   PubMed Web of Science ®Google Scholar
• Jain N, Zhang T, Fong SL, Lim CP, Cao X. Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK). Oncogene 1998; 17:3157 - 3167
   PubMed Web of Science ®Google Scholar
• Sengupta TK, Talbot ES, Scherle PA, Ivashkiv LB. Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases. Proc Natl Acad Sci USA 1998; 95:11107 - 11112
   PubMed Web of Science ®Google Scholar
• Loucks FA, Le SS, Zimmermann AK, Ryan KR, Barth H, Aktories K, et al. Rho family GTPase inhibition reveals opposing effects of mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and Janus kinase/signal transducer and activator of transcription signaling cascades on neuronal survival. J Neurochem 2006; 97:957 - 967
   PubMed Web of Science ®Google Scholar
• Stokoe D, Macdonald SG, Cadwallader K, Symons M, Hancock JF. Activation of Raf as a result of recruitment to the plasma membrane. Science 1994; 264:1463 - 1467
   PubMed Web of Science ®Google Scholar
• Muslin AJ, Tanner JW, Allen PM, Shaw AS. Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine. Cell 1996; 84:889 - 897
   PubMed Web of Science ®Google Scholar
• Davis RJ. MAPKs: new JNK expands the group. Trends Biochem Sci 1994; 19:470 - 473
   PubMed Web of Science ®Google Scholar
• Laird AD, Taylor SJ, Oberst M, Shalloway D. Raf-1 is activated during mitosis. J Biol Chem 1995; 270:26742 - 26745
   PubMed Web of Science ®Google Scholar
• Wang S, Ghosh RN, Chellappan SP. Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation. Mol Cell Biol 1998; 18:7487 - 7498
   PubMed Web of Science ®Google Scholar
• Eves EM, Shapiro P, Naik K, Klein UR, Trakul N, Rosner MR. Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. Mol Cell 2006; 23:561 - 574
   PubMed Web of Science ®Google Scholar
• Greene LM, Campiani G, Lawler M, Williams DC, Zisterer DM. BubR1 is required for a sustained mitotic spindle checkpoint arrest in human cancer cells treated with tubulin-targeting pyrrolo-1,5-benzoxapines. Mol Pharm 2008; 73:419 - 430
   PubMed Web of Science ®Google Scholar
• Taylor SS, Hussein D, Wang Y, Elderkin S, Morrow CJ. Kinetochore localization and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells. J Cell Sci 2001; 114:4385 - 4395
   PubMed Web of Science ®Google Scholar
• Choi E, Choe H, Min J, Choi JY, Kim J, Lee H. BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis. EMBO J 2009; 28:2077 - 2089
   PubMed Web of Science ®Google Scholar
• Oikawa T, Okuda M, Ma Z, Goorha R, Tsujimoti H, Inokuma H, et al. Transcriptional control of BubR1 by p53 and suppression of centrosome amplification by BubR1. Mol Cell Biol 2005; 25:4046 - 4061
   PubMed Web of Science ®Google Scholar
• Matsumura S, Toyoshima F, Nishida E. Polo-like kinase 1 facilitates chromosome alignment during prommetaphase through BubR1. J Biol Chem 2007; 282:15217 - 15227
   PubMed Web of Science ®Google Scholar
• Morrow CJ, Tighe A, Johnson VL, Scott MIF, Ditchfield C, Taylor SS. Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/C Cdc20. J Cell Sci 2005; 118:3639 - 3652
   PubMed Web of Science ®Google Scholar
• Wang Q, Liu T, Fang Y, Xie S, Huang X, Mahmood R, et al. BubR1 deficiency results in abnormal megakaryopoiesis. Blood 2004; 103:1278 - 1285
   PubMed Web of Science ®Google Scholar
• Cha H, Shapiro P. Tyrosine-phosphorylated extracellular signal—regulated kinase associates with the Golgi complex during G2/M phase of the cell cycle: evidence for regulation of Golgi structure. J Cell Biol 2001; 153:1355 - 1367
   PubMed Web of Science ®Google Scholar
• Smith J, Buncaciu RP, Reiterer G, Coder D, George T, Asaly M, et al. Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells. Exp Cell Res 2009; 315:2241 - 2248
   PubMed Web of Science ®Google Scholar
• Yang YL, Duan Q, Guo TB, Wang XX, Ruan Q, Xu GT, et al. BubR1 deficiency results in enhanced activation of MEK and ERKs upon microtubule stresses. Cell Prolif 2007; 40:397 - 410
   PubMed Web of Science ®Google Scholar
• Jorquera R, Tanguay RM. Fumarylacetoacetate, the metabolite accumulating in hereditary tyrosinemia, activates the ERK pathway and induces mitotic abnormalities and genomic instability. Hum Mol Genet 2001; 15:1741 - 1752
   Web of Science ®Google Scholar
• Prochownik EV. Functional and physical communication between oncoproteins and tumor suppressors. Cell Mol Life Sci 2005; 62:2438 - 2459
   PubMed Web of Science ®Google Scholar