Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin

References

• Bell SP, Dutta A. DNA replication in eukaryotic cells. Annu Rev Biochem 2002; 71:333 - 374
   PubMed Web of Science ®Google Scholar
• Bell SP, Stillman B. ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature 1992; 357:128 - 134
   PubMed Web of Science ®Google Scholar
• Cocker JH, Piatti S, Santocanale C, Nasmyth K, Diffley JFX. An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast. Nature 1996; 379:180 - 182
   PubMed Web of Science ®Google Scholar
• Tanaka S, Diffley JF. Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 2002; 4:198 - 207
   PubMed Web of Science ®Google Scholar
• Blow JJ, Hodgson B. Replication licensing—defining the proliferative state?. Trends Cell Biol 2002; 12:72 - 78
   PubMed Web of Science ®Google Scholar
• Perkins G, Diffley JFX. Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders. Molecular Cell 1998; 2:23 - 32
   PubMed Web of Science ®Google Scholar
• Ballabeni A, Melixetian M, Zamponi R, Masiero L, Marinoni F, Helin K. Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis. EMBO J 2004; 23:3122 - 3132
   PubMed Web of Science ®Google Scholar
• Lutzmann M, Maiorano D, Mechali M. A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus. EMBO J 2006; 25:5764 - 5774
   PubMed Web of Science ®Google Scholar
• Saxena S, Yuan P, Dhar SK, Senga T, Takeda D, Robinson H, et al. A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. Mol Cell 2004; 15:245 - 258
   PubMed Web of Science ®Google Scholar
• Carrozza MJ, Utley RT, Workman JL, Cote J. The diverse functions of histone acetyltransferase complexes. Trends Genet 2003; 19:321 - 329
   PubMed Web of Science ®Google Scholar
• Yang XJ, Seto E. HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention. Oncogene 2007; 26:5310 - 5318
   PubMed Web of Science ®Google Scholar
• Vogelauer M, Rubbi L, Lucas I, Brewer BJ, Grunstein M. Histone acetylation regulates the time of replication origin firing. Mol Cell 2002; 10:1223 - 1233
   PubMed Web of Science ®Google Scholar
• Aggarwal BD, Calvi BR. Chromatin regulates origin activity in Drosophila follicle cells. Nature 2004; 430:372 - 376
   PubMed Web of Science ®Google Scholar
• Goren A, Tabib A, Hecht M, Cedar H. DNA replication timing of the human beta-globin domain is controlled by histone modification at the origin. Genes Dev 2008; 22:1319 - 1324
   PubMed Web of Science ®Google Scholar
• Miotto B, Struhl K. HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1. Genes Dev 2008; 22:2633 - 2638
   PubMed Web of Science ®Google Scholar
• Miotto B, Struhl K. HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin. Mol Cell 2010; 37:57 - 66
   PubMed Web of Science ®Google Scholar
• Glozak MA, Seto E. Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1. J Biol Chem 2009; 284:11446 - 11453
   PubMed Web of Science ®Google Scholar
• Gao L, Cueto MA, Asselbergs F, Atadja P. Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family. J Biol Chem 2002; 277:25748 - 25755
   PubMed Web of Science ®Google Scholar
• Villagra A, Cheng F, Wang HW, Suarez I, Glozak M, Maurin M, et al. The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance. Nat Immunol 2009; 10:92 - 100
   PubMed Web of Science ®Google Scholar
• Vaziri C, Saxena S, Jeon Y, Lee C, Murata K, Machida Y, et al. A p53-dependent checkpoint pathway prevents rereplication. Mol Cell 2003; 11:997 - 1008
   PubMed Web of Science ®Google Scholar
• Iizuka M, Matsui T, Takisawa H, Smith MM. Regulation of replication licensing by acetyltransferase Hbo1. Mol Cell Biol 2006; 26:1098 - 1108
   PubMed Web of Science ®Google Scholar
• Wohlschlegel JA, Dwyer BT, Dhar SK, Cvetic C, Walter JC, Dutta A. Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. Science 2000; 290:2309 - 2312
   PubMed Web of Science ®Google Scholar
• Arias EE, Walter JC. Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts. Genes Dev 2005; 19:114 - 126
   PubMed Web of Science ®Google Scholar
• Tumbar T, Sudlow G, Belmont AS. Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain. J Cell Biol 1999; 145:1341 - 1354
   PubMed Web of Science ®Google Scholar
• Alexandrow MG, Hamlin JL. Chromatin decondensation in S-phase involves recruitment of Cdk2 by Cdc45 and histone H1 phosphorylation. J Cell Biol 2005; 168:875 - 886
   PubMed Web of Science ®Google Scholar
• Li G, Sudlow G, Belmont AS. Interphase cell cycle dynamics of a late-replicating, heterochromatic homogeneously staining region: Precise choreography of condensation/decondensation and nuclear positioning. J Cell Biol 1998; 140:975 - 989
   PubMed Web of Science ®Google Scholar
• Ye Q, Hu YF, Zhong H, Nye AC, Belmont AS, Li R. BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. J Cell Biol 2001; 155:911 - 921
   PubMed Web of Science ®Google Scholar
• Nye AC, Rajendran RR, Stenoien DL, Mancini MA, Katzenellenbogen BS, Belmont AS. Alteration of largescale chromatin structure by estrogen receptor. Mol Cell Biol 2002; 22:3437 - 3449
   PubMed Web of Science ®Google Scholar
• Verschure PJ, van der Kraan I, de Leeuw W, van der Vlag J, Carpenter AE, Belmont AS, et al. In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation. Mol Cell Biol 2005; 25:4552 - 4564
   PubMed Web of Science ®Google Scholar
• Lu MJ, Dadd CA, Mizzen CA, Perry CA, McLachlan DR, Annunziato AT, et al. Generation and characterization of novel antibodies highly selective for phosphorylated linker histone H1 in Tetrahymena and HeLa cells. Chromosoma 1994; 103:111 - 121
   PubMed Web of Science ®Google Scholar
• Teer JK, Dutta A. Human Cdt1 lacking the evolutionarily conserved region that interacts with MCM2-7 is capable of inducing re-replication. J Biol Chem 2008; 283:6817 - 6825
   PubMed Web of Science ®Google Scholar
• Mukherjee P, Cao TV, Winter SL, Alexandrow MG. Mammalian MCM loading in late-G(1) coincides with Rb hyperphosphorylation and the transition to posttranscriptional control of progression into S-phase. PLoS ONE 2009; 4:e5462
   PubMed Web of Science ®Google Scholar
• Yanagi K, Mizuno T, You Z, Hanaoka F. Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity. J Biol Chem 2002; 277:40871 - 40880
   PubMed Web of Science ®Google Scholar
• Doyon Y, Cayrou C, Ullah M, Landry AJ, Cote V, Selleck W, et al. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation. Mol Cell 2006; 21:51 - 64
   PubMed Web of Science ®Google Scholar
• Yin Y, Yu VC, Zhu G, Chang DC. SET8 plays a role in controlling G1/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail. Cell Cycle 2008; 7:1423 - 1432
   PubMed Web of Science ®Google Scholar
• Djeliova V, Russev G, Anachkova B. DNase I sensitive site in the core region of the human beta-globin origin of replication. J Cell Biochem 2002; 87:279 - 283
   PubMed Web of Science ®Google Scholar
• Zimmermann K, Holtz M, Phi-van L. The chromatin structure of the lysozyme GAS41 origin of DNA replication changes during the cell cycle. Biol Res 2007; 40:185 - 192
   PubMed Web of Science ®Google Scholar
• Pemov A, Bavykin S, Hamlin JL. Attachment to the nuclear matrix mediates specific alterations in chromatin structure. Proc Natl Acad Sci USA 1998; 95:14757 - 14762
   PubMed Web of Science ®Google Scholar
• Cook JG, Chasse DA, Nevins JR. The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells. J Biol Chem 2004; 279:9625 - 9633
   PubMed Web of Science ®Google Scholar
• Shogren-Knaak M, Ishii H, Sun JM, Pazin MJ, Davie JR, Peterson CL. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 2006; 311:844 - 847
   PubMed Web of Science ®Google Scholar
• Strahl BD, Allis CD. The language of covalent histone modification. Nature 2000; 403:41 - 45
   PubMed Web of Science ®Google Scholar
• Sugimoto N, Kitabayashi I, Osano S, Tatsumi Y, Yugawa T, Narisawa-Saito M, et al. Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. Mol Biol Cell 2008; 19:1007 - 1021
   PubMed Web of Science ®Google Scholar
• Hakimi MA, Bochar DA, Schmiesing JA, Dong Y, Barak OG, Speicher DW, et al. A chromatin remodelling complex that loads cohesin onto human chromosomes. Nature 2002; 418:994 - 998
   PubMed Web of Science ®Google Scholar
• Arentson E, Faloon P, Seo J, Moon E, Studts JM, Fremont DH, et al. Oncogenic potential of the DNA replication licensing protein CDT1. Oncogene 2002; 21:1150 - 1158
   PubMed Web of Science ®Google Scholar
• Seo J, Chung YS, Sharma GG, Moon E, Burack WR, Pandita TK, et al. Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53. Oncogene 2005; 24:8176 - 8186
   PubMed Web of Science ®Google Scholar
• Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, et al. Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior. Cancer Res 2007; 67:10899 - 10909
   PubMed Web of Science ®Google Scholar
• Mukherjee P, Winter SL, Alexandrow MG. Cell cycle arrest by transforming growth factor beta1 near G1/S is mediated by acute abrogation of prereplication complex activation involving an Rb-MCM interaction. Mol Cell Biol 2010; 30:845 - 856
   PubMed Web of Science ®Google Scholar
• Mendez J, Stillman B. Chromatin association of human origin recognition complex, cdc6 and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis. Mol Cell Biol 2000; 20:8602 - 8612
   PubMed Web of Science ®Google Scholar
• Ladenburger EM, Keller C, Knippers R. Identification of a binding region for human origin recognition complex proteins 1 and 2 that coincides with an origin of DNA replication. Mol Cell Biol 2002; 22:1036 - 1048
   PubMed Web of Science ®Google Scholar
• Sibani S, Price GB, Zannis-Hadjopoulos M. Decreased origin usage and initiation of DNA replication in haploinsufficient HCT116 Ku80+/− cells. J Cell Sci 2005; 118:3247 - 3261
   PubMed Web of Science ®Google Scholar
• Birch JL, Tan BC, Panov KI, Panova TB, Andersen JS, Owen-Hughes TA, et al. FACT facilitates chromatin transcription by RNA polymerases I and III. EMBO J 2009; 28:854 - 865
   PubMed Web of Science ®Google Scholar