The Mek1 phosphorylation cascade plays a role in meiotic recombination of Schizosaccharomyces pombe

References

• Ciccia A, McDonald N, West SC. Structural and Functional Relationships of the XPF/MUS81 Family of Proteins. Annu Rev Biochem 2008; 77:259 - 287
   PubMed Web of Science ®Google Scholar
• Smith GR. Genetic analysis of meiotic recombination in Schizosaccharomyces pombe. Methods Mol Biol 2009; 557:65 - 76
   PubMedGoogle Scholar
• Huertas P. DNA resection in eukaryotes: Deciding how to fix the break. Nat Struct Mol Biol 2010; 17:11 - 16
   PubMed Web of Science ®Google Scholar
• Niu H, Wan L, Baumgartner B, Schaefer D, Loidl J, Hollingsworth NM. Partner choice during meiosis is regulated by Hop1-promoted dimerization of Mek1. Mol Biol Cell 2005; 16:5804 - 5818
   PubMed Web of Science ®Google Scholar
• Cartagena-Lirola H, Guerini I, Manfrini N, Lucchini G, Longhese MP. Roles of the S. cerevisiae Rad53 checkpoint kinase in signalling double-strand breaks during the meiotic cell cycle. Mol Cell Biol 2008; 28:4480 - 4493
   PubMed Web of Science ®Google Scholar
• Berchowitz LE, Hanlon SE, Lieb JD, Copenhaver GP. A positive but complex association between meiotic double-strand break hotspots and open chromatin in Saccharomyces cerevisiae. Genome Res 2009; 19:2245 - 2257
   PubMed Web of Science ®Google Scholar
• Joshi N, Barot A, Jamison C, Börner GV. Pch2 links chromosome axis remodeling at future crossover sites and crossover distribution during yeast meiosis. PLoS Genet 2009; 5:1000557
   PubMed Web of Science ®Google Scholar
• Lin FM, Lai YJ, Shen HJ, Cheng YH, Wang TF. Yeast axial-element protein, Red1, binds SUMO chains to promote meiotic interhomologue recombination and chromosome synapsis. EMBO J 2010; 29:586 - 596
   PubMed Web of Science ®Google Scholar
• Bailis JM, Roeder GS. Pachytene exit controlled by reversal of Mek1-dependent phosphorylation. Cell 2000; 101:211 - 221
   PubMed Web of Science ®Google Scholar
• Wan L, de los Santos T, Zhang C, Shokat K, Hollingsworth NM. Mek1 kinase activity functions downstream of RED1 in the regulation of meiotic double strand break repair in budding yeast. Mol Biol Cell 2004; 15:11 - 23
   PubMed Web of Science ®Google Scholar
• Niu H, Li X, Job E, Park C, Moazed D, Gygi SP, et al. Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis. Mol Cell Biol 2007; 27:5456 - 5467
   PubMed Web of Science ®Google Scholar
• Carballo JA, Johnson AL, Sedgwick SG, Cha RS. Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination. Cell 2008; 132:758 - 770
   PubMed Web of Science ®Google Scholar
• Cromie G, Smith GR. Egel R, Lankenau DH. Meiotic Recombination in Schizosaccharomyces pombe: A Paradigm for Genetic and Molecular Analysis. Recombination and Meiosis 2007; 3:Berlin Springer 196 - 230
   Google Scholar
• Cromie GA, Hyppa RW, Taylor AF, Zakharyevich K, Hunter N, Smith GR. Single Holliday junctions are intermediates of meiotic recombination. Cell 2006; 27:1167 - 1178
   Web of Science ®Google Scholar
• Latypov V, Rothenberg M, Lorenz A, Octobre G, Csutak O, Lehmann E, et al. The roles of Hop1 and Mek1 in meiotic chromosome pairing and recombination-partner choice in Schizosaccharomyces pombe. Mol Cell Biol 2010; 30:1570 - 1581
   PubMed Web of Science ®Google Scholar
• Rhind N, Russell P. Chk1 and Cds1: Linchpins of the DNA damage and replication checkpoint pathways. J Cell Sci 2000; 113:3889 - 3896
   PubMed Web of Science ®Google Scholar
• Branzei D, Foiani M. The Rad53 signal transduction pathway: Replication fork stabilization, DNA repair and adaptation. Exp Cell Res 2006; 312:2654 - 269
   PubMed Web of Science ®Google Scholar
• Chen Y, Poon RY. The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability. Front Biosci 2008; 13:5016 - 5029
   PubMed Web of Science ®Google Scholar
• Tanaka K, Russell P. Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1. Nat Cell Biol 2001; 3:966 - 972
   PubMed Web of Science ®Google Scholar
• Tanaka K, Russell P. Cds1 phosphorylation by Rad3-Rad26 kinase is mediated by forkhead-associated domain interaction with Mrc1. J Biol Chem 2004; 279:32079 - 32086
   PubMed Web of Science ®Google Scholar
• Xu YJ, Davenport M, Kelly TJ. Two-stage mechanism for activation of the DNA replication checkpoint kinase Cds1 in fission yeast. Genes Dev 2006; 20:990 - 1003
   PubMed Web of Science ®Google Scholar
• Ogino K, Masai H. Rad3-Cds1 mediates coupling of initiation of meiotic recombination with DNA replication. Mei4-dependent transcription as a potential target of meiotic checkpoint. J Biol Chem 2006; 281:1338 - 1344
   PubMed Web of Science ®Google Scholar
• Shimada M, Nabeshima K, Tougan T, Nojima H. The meiotic recombination checkpoint is regulated by checkpoint rad+ genes in fission yeast. EMBO J 2002; 21:2807 - 2818
   PubMed Web of Science ®Google Scholar
• Pérez-Hidalgo L, Moreno S, San-Segundo PA. Regulation of meiotic progression by the meiosis-specific checkpoint kinase Mek1 in fission yeast. J Cell Sci 2003; 116:259 - 271
   PubMed Web of Science ®Google Scholar
• Boddy MN, Lopez-Girona A, Shanahan P, Interthal H, Heyer WD, Russell P. Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1. Mol Cell Biol 2000; 20:8758 - 8766
   PubMed Web of Science ®Google Scholar
• Boddy MN, Gaillard PH, McDonald WH, Shanahan P, Yates JR 3rd, Russell P. Mus81-Eme1 are essential components of a Holliday junction resolvase. Cell 2001; 107:537 - 548
   PubMed Web of Science ®Google Scholar
• Smith GR, Boddy MN, Shanahan P, Russell P. Fission yeast Mus81. Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion. Genetics 2003; 65:2289 - 2293
   Google Scholar
• Holzen TM, Shah PP, Olivares HA, Bishop DK. Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatin. Genes Dev 2006; 20:2593 - 604
   PubMed Web of Science ®Google Scholar
• Nimonkar AV, Amitani I, Baskin RJ, Kowalczykowski SC. Single molecule imaging of Tid1/Rdh54, a Rad54 homolog that translocates on duplex DNA and can disrupt joint molecules. J Biol Che 2007; 282:30776 - 30784
   Google Scholar
• Catlett MG, Forsburg SL. Schizosaccharomyces pombe Rdh54 (TID1) acts with Rhp54 (RAD54) to repair meiotic double-strand breaks. Mol Biol Cell 2003; 14:4707 - 4720
   PubMed Web of Science ®Google Scholar
• Chi P, Kwon Y, Moses DN, Seong C, Sehorn MG, Singh AK, et al. Functional interactions of meiotic recombination factors Rdh54 and Dmc1. DNA Repair (Amst) 2009; 8:279 - 284
   PubMed Web of Science ®Google Scholar
• Kai M, Boddy MN, Russell P, Wang TS. Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress. Genes Dev 2005; 19:919 - 932
   PubMed Web of Science ®Google Scholar
• Cervantes MD, Farah JA, Smith GR. Meiotic DNA breaks associated with recombination in S. pombe. Mol Cell 2000; 5:883 - 888
   PubMed Web of Science ®Google Scholar
• Limbo O, Chahwan C, Yamada Y, de Bruin RA, Wittenberg C, Russell P. Ctp1 is a cell cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol Cell 2007; 28:134 - 146
   PubMed Web of Science ®Google Scholar
• Hartsuiker E, Mizuno K, Molnar M, Kohli J, Ohta K, Carr AM. Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions. Mol Cell Biol 2009; 29:1671 - 1681
   PubMed Web of Science ®Google Scholar
• Rothenberg M, Kohli J, Ludin K. Ctp1 and the MRN-complex are required for endonucleolytic Rec12 removal with release of a single class of oligonucleotides in fission yeast. PLoS Genet 2009; 5:1000722
   PubMed Web of Science ®Google Scholar
• Ahn J, Urist M, Prives C. The Chk2 protein kinase. DNA Repair (Amst) 2004; 3:1039 - 1047
   PubMed Web of Science ®Google Scholar
• Saito TT, Tougan T, Kasama T, Okuzaki D, Nojima H. Mcp7, a meiosis-specific coiled-coil protein of fission yeast, associates with Meu13 and is required for meiotic recombination. Nucleic Acids Res 2004; 32:3325 - 3339
   PubMed Web of Science ®Google Scholar
• Tanaka K, Kohda T, Yamashita A, Nonaka N, Yamamoto M. Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement. Curr Biol 2005; 15:1479 - 1486
   PubMed Web of Science ®Google Scholar
• Nabeshima K, Kakihara Y, Hiraoka Y, Nojima H. A novel meiosis-specific protein of fission yeast, Meu13p, promotes homologous pairing independently of homologous recombination. EMBO J 2001; 20:3871 - 3881
   PubMed Web of Science ®Google Scholar
• Yang S, Jeong JH, Brown AL, Lee CH, Pandolfi PP, Chung JH, et al. Promyelocytic leukemia activates Chk2 by mediating Chk2 autophosphorylation. J Biol Chem 2006; 281:26645 - 26654
   PubMed Web of Science ®Google Scholar
• Fiorani S, Mimun G, Caleca L, Piccini D, Pellicioli A. Characterization of the activation domain of the Rad53 checkpoint kinase. Cell Cycle 2008; 7:493 - 499
   PubMed Web of Science ®Google Scholar
• Cai Z, Chehab NH, Pavletich NP. Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase. Mol Cell 2009; 35:818 - 829
   PubMed Web of Science ®Google Scholar
• Raffa GD, Wohlschlegel J, Yates JR 3rd, Boddy MN. SUMO-binding motifs mediate the Rad60-dependent response to replicative stress and self-association. J Biol Chem 2006; 281:27973 - 27981
   PubMed Web of Science ®Google Scholar
• Miyabe I, Morishita T, Shinagawa H, Carr AM. Schizosaccharomyces pombe Cds1Chk2 regulates homologous recombination at stalled replication forks through the phosphorylation of recombination protein Rad60. J Cell Sci 2009; 122:3638 - 3643
   PubMed Web of Science ®Google Scholar
• de Bruin RA, Kalashnikova TI, Aslanian A, Wohlschlegel J, Chahwan C, Yates JR 3rd, et al. DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1. Proc Natl Acad Sci USA 2008; 105:11230 - 11235
   PubMed Web of Science ®Google Scholar
• Pérez-Hidalgo L, Moreno S, San-Segundo PA. The fission yeast meiotic checkpoint kinase Mek1 regulates nuclear localization of Cdc25 by phosphorylation. Cell Cycle 2008; 7:3720 - 3730
   PubMed Web of Science ®Google Scholar