A plasma membrane-targeted cytosolic domain of STIM1 selectively activates ARC channels, an arachidonate-regulated store-independent Orai channel

References

• Ji W, Xu P, Li Z, Lu J, Liu L, Zhan Y, et al. Functional stoichiometry of the unitary calcium-release-activated calcium channel. Proc Natl Acad Sci USA 2008; 105:13668 - 73; http://dx.doi.org/10.1073/pnas.0806499105; PMID: 18757751
   PubMed Web of Science ®Google Scholar
• Mignen O, Thompson JL, Shuttleworth TJ. Orai1 subunit stoichiometry of the mammalian CRAC channel pore. J Physiol 2008; 586:419 - 25; http://dx.doi.org/10.1113/jphysiol.2007.147249; PMID: 18006576
   PubMed Web of Science ®Google Scholar
• Penna A, Demuro A, Yeromin AV, Zhang SL, Safrina O, Parker I, et al. The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Nature 2008; 456:116 - 20; http://dx.doi.org/10.1038/nature07338; PMID: 18820677
   PubMed Web of Science ®Google Scholar
• Mignen O, Thompson JL, Shuttleworth TJ. Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels. J Physiol 2008; 586:185 - 95; http://dx.doi.org/10.1113/jphysiol.2007.146258; PMID: 17991693
   PubMed Web of Science ®Google Scholar
• Mignen O, Thompson JL, Shuttleworth TJ. The molecular architecture of the arachidonate-regulated Ca2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits. J Physiol 2009; 587:4181 - 97; http://dx.doi.org/10.1113/jphysiol.2009.174193; PMID: 19622606
   PubMed Web of Science ®Google Scholar
• Liou J, Kim ML, Heo WD, Jones JT, Myers JW, Ferrell JE Jr., et al. STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx. Curr Biol 2005; 15:1235 - 41; http://dx.doi.org/10.1016/j.cub.2005.05.055; PMID: 16005298
   PubMed Web of Science ®Google Scholar
• Zhang SL, Yu Y, Roos J, Kozak JA, Deerinck TJ, Ellisman MH, et al. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature 2005; 437:902 - 5; http://dx.doi.org/10.1038/nature04147; PMID: 16208375
   PubMed Web of Science ®Google Scholar
• Wu MM, Buchanan J, Luik RM, Lewis RS. Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane. J Cell Biol 2006; 174:803 - 13; http://dx.doi.org/10.1083/jcb.200604014; PMID: 16966422
   PubMed Web of Science ®Google Scholar
• Baba Y, Hayashi K, Fujii Y, Mizushima A, Watarai H, Wakamori M, et al. Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum. Proc Natl Acad Sci USA 2006; 103:16704 - 9; http://dx.doi.org/10.1073/pnas.0608358103; PMID: 17075073
   PubMed Web of Science ®Google Scholar
• Mercer JC, Dehaven WI, Smyth JT, Wedel B, Boyles RR, Bird GS, et al. Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J Biol Chem 2006; 281:24979 - 90; http://dx.doi.org/10.1074/jbc.M604589200; PMID: 16807233
   PubMed Web of Science ®Google Scholar
• Liou J, Fivaz M, Inoue T, Meyer T. Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion. Proc Natl Acad Sci USA 2007; 104:9301 - 6; http://dx.doi.org/10.1073/pnas.0702866104; PMID: 17517596
   PubMed Web of Science ®Google Scholar
• Luik RM, Wang B, Prakriya M, Wu MM, Lewis RS. Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation. Nature 2008; 454:538 - 42; http://dx.doi.org/10.1038/nature07065; PMID: 18596693
   PubMed Web of Science ®Google Scholar
• Park CY, Hoover PJ, Mullins FM, Bachhawat P, Covington ED, Raunser S, et al. STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell 2009; 136:876 - 90; http://dx.doi.org/10.1016/j.cell.2009.02.014; PMID: 19249086
   PubMed Web of Science ®Google Scholar
• Yuan JP, Zeng W, Dorwart MR, Choi YJ, Worley PF, Muallem S. SOAR and the polybasic STIM1 domains gate and regulate Orai channels. Nat Cell Biol 2009; 11:337 - 43; http://dx.doi.org/10.1038/ncb1842; PMID: 19182790
   PubMed Web of Science ®Google Scholar
• Mignen O, Thompson JL, Shuttleworth TJ. STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane. J Physiol 2007; 579:703 - 15; http://dx.doi.org/10.1113/jphysiol.2006.122432; PMID: 17158173
   PubMed Web of Science ®Google Scholar
• Manji SS, Parker NJ, Williams RT, van Stekelenburg L, Pearson RB, Dziadek M, et al. STIM1: a novel phosphoprotein located at the cell surface. Biochim Biophys Acta 2000; 1481:147 - 55; http://dx.doi.org/10.1016/S0167-4838(00)00105-9; PMID: 11004585
   PubMed Web of Science ®Google Scholar
• Stathopulos PB, Li GY, Plevin MJ, Ames JB, Ikura M. Stored Ca2+ depletion-induced oligomerization of stromal interaction molecule 1 (STIM1) via the EF-SAM region: An initiation mechanism for capacitive Ca2+ entry. J Biol Chem 2006; 281:35855 - 62; http://dx.doi.org/10.1074/jbc.M608247200; PMID: 17020874
   PubMed Web of Science ®Google Scholar
• Zheng L, Stathopulos PB, Schindl R, Li GY, Romanin C, Ikura M. Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry. Proc Natl Acad Sci USA 2011; 108:1337 - 42; http://dx.doi.org/10.1073/pnas.1015125108; PMID: 21217057
   PubMed Web of Science ®Google Scholar
• Hauser CT, Tsien RY. A hexahistidine-Zn2+-dye label reveals STIM1 surface exposure. Proc Natl Acad Sci USA 2007; 104:3693 - 7; http://dx.doi.org/10.1073/pnas.0611713104; PMID: 17360414
   PubMed Web of Science ®Google Scholar
• Muik M, Fahrner M, Derler I, Schindl R, Bergsmann J, Frischauf I, et al. A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels. J Biol Chem 2009; 284:8421 - 6; http://dx.doi.org/10.1074/jbc.C800229200; PMID: 19189966
   PubMed Web of Science ®Google Scholar
• Covington ED, Wu MM, Lewis RS. Essential role for the CRAC activation domain in store-dependent oligomerization of STIM1. Mol Biol Cell 2010; 21:1897 - 907; http://dx.doi.org/10.1091/mbc.E10-02-0145; PMID: 20375143
   PubMed Web of Science ®Google Scholar
• Huang GN, Zeng W, Kim JY, Yuan JP, Han L, Muallem S, et al. STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat Cell Biol 2006; 8:1003 - 10; http://dx.doi.org/10.1038/ncb1454; PMID: 16906149
   PubMed Web of Science ®Google Scholar
• Muik M, Frischauf I, Derler I, Fahrner M, Bergsmann J, Eder P, et al. Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. J Biol Chem 2008; 283:8014 - 22; http://dx.doi.org/10.1074/jbc.M708898200; PMID: 18187424
   PubMed Web of Science ®Google Scholar
• Zhang SL, Kozak JA, Jiang W, Yeromin AV, Chen J, Yu Y, et al. Store-dependent and -independent modes regulating Ca2+ release-activated Ca2+ channel activity of human Orai1 and Orai3. J Biol Chem 2008; 283:17662 - 71; http://dx.doi.org/10.1074/jbc.M801536200; PMID: 18420579
   PubMed Web of Science ®Google Scholar
• Kawasaki T, Lange I, Feske S. A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels. Biochem Biophys Res Commun 2009; 385:49 - 54; http://dx.doi.org/10.1016/j.bbrc.2009.05.020; PMID: 19433061
   PubMed Web of Science ®Google Scholar
• Li Z, Lu J, Xu P, Xie X, Chen L, Xu T. Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation. J Biol Chem 2007; 282:29448 - 56; http://dx.doi.org/10.1074/jbc.M703573200; PMID: 17702753
   PubMed Web of Science ®Google Scholar
• Wang Y, Deng X, Zhou Y, Hendron E, Mancarella S, Ritchie MF, et al. STIM protein coupling in the activation of Orai channels. Proc Natl Acad Sci USA 2009; 106:7391 - 6; http://dx.doi.org/10.1073/pnas.0900293106; PMID: 19376967
   PubMed Web of Science ®Google Scholar
• Koegl M, Zlatkine P, Ley SC, Courtneidge SA, Magee AI. Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif. Biochem J 1994; 303:749 - 53; PMID: 7980442
   PubMed Web of Science ®Google Scholar
• Kwong J, Lublin DM. Amino-terminal palmitate or polybasic domain can provide required second signal to myristate for membrane binding of p56lck. Biochem Biophys Res Commun 1995; 207:868 - 76; http://dx.doi.org/10.1006/bbrc.1995.1266; PMID: 7864883
   PubMed Web of Science ®Google Scholar
• Bijlmakers MJ, Isobe-Nakamura M, Ruddock LJ, Marsh M. Intrinsic signals in the unique domain target p56(lck) to the plasma membrane independently of CD4. J Cell Biol 1997; 137:1029 - 40; http://dx.doi.org/10.1083/jcb.137.5.1029; PMID: 9166404
   PubMed Web of Science ®Google Scholar
• Zlatkine P, Mehul B, Magee AI. Retargeting of cytosolic proteins to the plasma membrane by the Lck protein tyrosine kinase dual acylation motif. J Cell Sci 1997; 110:673 - 9; PMID: 9092949
   PubMed Web of Science ®Google Scholar
• McCabe JB, Berthiaume LG. Functional roles for fatty acylated amino-terminal domains in subcellular localization. Mol Biol Cell 1999; 10:3771 - 86; PMID: 10564270
   PubMed Web of Science ®Google Scholar
• Yasuda K, Kosugi A, Hayashi F, Saitoh S, Nagafuku M, Mori Y, et al. Serine 6 of Lck tyrosine kinase: a critical site for Lck myristoylation, membrane localization, and function in T lymphocytes. J Immunol 2000; 165:3226 - 31; PMID: 10975838
   PubMed Web of Science ®Google Scholar
• Hancock JF, Paterson H, Marshall CJ. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane. Cell 1990; 63:133 - 9; http://dx.doi.org/10.1016/0092-8674(90)90294-O; PMID: 2208277
   PubMed Web of Science ®Google Scholar
• Roy MO, Leventis R, Silvius JR. Mutational and biochemical analysis of plasma membrane targeting mediated by the farnesylated, polybasic carboxy terminus of K-ras4B. Biochemistry 2000; 39:8298 - 307; http://dx.doi.org/10.1021/bi000512q; PMID: 10889039
   PubMed Web of Science ®Google Scholar
• Mignen O, Shuttleworth TJ. I(ARC), a novel arachidonate-regulated, noncapacitative Ca(2+) entry channel. J Biol Chem 2000; 275:9114 - 9; http://dx.doi.org/10.1074/jbc.275.13.9114; PMID: 10734044
   PubMed Web of Science ®Google Scholar
• Williams RT, Senior PV, Van Stekelenburg L, Layton JE, Smith PJ, Dziadek MA. Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation. Biochim Biophys Acta 2002; 1596:131 - 7; http://dx.doi.org/10.1016/S0167-4838(02)00211-X; PMID: 11983428
   PubMed Web of Science ®Google Scholar
• Spassova MA, Soboloff J, He LP, Xu W, Dziadek MA, Gill DL. STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels. Proc Natl Acad Sci USA 2006; 103:4040 - 5; http://dx.doi.org/10.1073/pnas.0510050103; PMID: 16537481
   PubMed Web of Science ®Google Scholar
• Hewavitharana T, Deng X, Wang Y, Ritchie MF, Girish GV, Soboloff J, et al. Location and function of STIM1 in the activation of Ca2+ entry signals. J Biol Chem 2008; 283:26252 - 62; http://dx.doi.org/10.1074/jbc.M802239200; PMID: 18635545
   PubMed Web of Science ®Google Scholar
• Soboloff J, Spassova MA, Hewavitharana T, He LP, Xu W, Johnstone LS, et al. STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ Entry. Curr Biol 2006; 16:1465 - 70; http://dx.doi.org/10.1016/j.cub.2006.05.051; PMID: 16860747
   PubMed Web of Science ®Google Scholar
• Stathopulos PB, Zheng L, Li GY, Plevin MJ, Ikura M. Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry. Cell 2008; 135:110 - 22; http://dx.doi.org/10.1016/j.cell.2008.08.006; PMID: 18854159
   PubMed Web of Science ®Google Scholar
• Thompson JL, Shuttleworth TJ. Orai channel-dependent activation of phospholipase C-δ: a novel mechanism for the effects of calcium entry on calcium oscillations. J Physiol 2011; 589:5057 - 69; http://dx.doi.org/10.1113/jphysiol.2011.214437; PMID: 21878525
   PubMed Web of Science ®Google Scholar