Regulation of neuronal functions by the E3-ubiquitinligase Protein Associated with MYC (MYCBP2)

References

• Guo Q, Xie J, Dang CV, Liu AT, Bishop JM. Identification of a large Myc-binding protein that contains RCC1-like repeats. Proc Natl Acad Sci USA 1998; 95:9172 - 9177
   PubMed Web of Science ®Google Scholar
• Yang H, Scholich K, Poser S, Storm DR, Patel TB, Goldowitz D. Developmental expression of PAM (protein associated with MYC) in the rodent brain. Brain Res Dev Brain Res 2002; 136:35 - 42
   PubMedGoogle Scholar
• Ehnert C, Tegeder I, Pierre SC, Birod K, Nguyen HV, Schmidtko A, et al. Protein associated with Myc (PAM) is involved in spinal nociceptive processing. J Neurochem 2004; 88:948 - 957
   PubMed Web of Science ®Google Scholar
• Scholich K, Pierre SC, Patel TB. Protein associated with Myc (PAM) is a potent inhibitor of adenylyl cyclases. J Biol Chem 2001; 276:47583 - 47589
   PubMed Web of Science ®Google Scholar
• Pierre SC, Häusler J, Birod K, Geisslinger G, Scholich K. PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate. EMBO J 2004; 23:3031 - 3040
   PubMed Web of Science ®Google Scholar
• McCabe BD, Hom S, Aberle H, Fetter RD, Marques G, Haerry TE, et al. Highwire regulates presynaptic BMP signaling essential for synaptic growth. Neuron 2004; 41:891 - 905
   PubMed Web of Science ®Google Scholar
• Maeurer C, Holland S, Pierre S, Potstada W, Scholich K. Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM. Cell Signal 2009; 21:293 - 300
   PubMed Web of Science ®Google Scholar
• Han SWR, Santos TM, Polizzano C, Sabatini BL, Ramesh V. Pam (Protein associated with Myc) functions as an E3 Ubiquitin ligase and regulates TSC/mTOR signaling. Cell Signal 2008; 20:1084 - 1091
   PubMed Web of Science ®Google Scholar
• Nakata KAB, Grill B, Goncharov A, Huang X, Chisholm AD, Jin Y. Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development. Cell 2005; 120:407 - 420
   PubMed Web of Science ®Google Scholar
• Pierre S, Eschenhagen T, Geisslinger G, Scholich K. Capturing adenylyl cyclases as potential drug targets. Nat Rev Drug Discov 2009; 8:321 - 335
   PubMed Web of Science ®Google Scholar
• Ji RRST, Jin SX, Schmoll R, Woolf CJ. p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 2002; 36:57 - 68
   PubMed Web of Science ®Google Scholar
• Kumar S, Boehm J, Lee JC. p38 MAP kinases: key signaling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov 2003; 2:717 - 726
   PubMed Web of Science ®Google Scholar
• Huang CC, You JL, Wu MY, Hsu KS. Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3,5-dihydroxyphenylglycene-induced long term depression. J Biol Chem 2004; 279:12286 - 12292
   PubMedGoogle Scholar
• Mace G, Miaczynska M, Zerial M, Nebreda A R. Phosphorylation of EEA1 by p38 MAP kinase regulates mu opioid receptor endocytosis. EMBO J 2005; 24:3235 - 3246
   PubMed Web of Science ®Google Scholar
• Zwang Y, Yarden Y. p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy. EMBO J 2006; 25:4195 - 4206
   PubMed Web of Science ®Google Scholar
• Frey MR, Dise RS, Edelblum KL, Polk D B. p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration. EMBO J 25:5683 - 5692
   PubMed Web of Science ®Google Scholar
• Tong J, Taylor P, Peterman SM, Prakash A, Moran MF. Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041. Mol Cell Proteomics 2009; 8:2131 - 2144
   PubMed Web of Science ®Google Scholar
• Park EC, Glodowski DR, Rongo C. The ubiquitin ligase RPM-1 and the p38 MAPK PMK-3 regulate AMPA receptor trafficking. PLoS One 2009; 4:4284
   Web of Science ®Google Scholar
• Goswami C. Structural and functional regulation of growth cone, filopodia and synaptic sites by TRPV1. Commun Integr Biol 2010; 3:614 - 618
   PubMedGoogle Scholar
• Goswami C, Schmidt H, Hucho F. TRPV1 at nerve endings regulates growth cone morphology and movement through cytoskeleton reorganization. FEBS J 2007; 274:760 - 772
   PubMed Web of Science ®Google Scholar
• Grill BBW, Brown HM, Ackley BD, Quadroni M, Jin Y. C. elegans RPM-1 regulates axon termination and synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1. Neuron 2007; 55:587 - 601
   PubMed Web of Science ®Google Scholar
• Zhen M, Huang X, Bamber B, Jin Y. Regulation of presynaptic terminal organization by C. elegans RPM-1, a putative guanine nucleotide exchanger with a RING-H2 finger domain. Neuron 2000; 26:331 - 343
   PubMed Web of Science ®Google Scholar
• Schaefer AM, Hadwiger GD, Nonet ML. rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in C. elegans. Neuron 2000; 26:345 - 356
   PubMed Web of Science ®Google Scholar
• Bloom AJMB, Sanes JR, DiAntonio A. The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons. Genes Dev 2007; 21:2593 - 2606
   PubMed Web of Science ®Google Scholar
• Holland S, Coste O, Zhang DD, Pierre SC, Geisslinger G, Scholich K. The ubiquitin ligase MYCBP2 regulates transient receptor potential vanilloid receptor 1 (TRPV1) internalization through inhibition of p38 MAPK signaling. J Biol Chem 2011; 286:3671 - 3680
   Google Scholar
• Burgess RWPK, Johnson MJ, Roix JJ, Welsh IC, O'Brien TP. Evidence for a conserved function in synapse formation reveals Phr1 as a candidate gene for respiratory failure in newborn mice. Mol Cell Biol 2004; 24:1096 - 1105
   PubMedGoogle Scholar
• Wan HIDA, Fetter RD, Bergstrom K, Strauss R, Goodman CS. Highwire regulates synaptic growth in Drosophila. Neuron 2000; 26:313 - 329
   PubMed Web of Science ®Google Scholar
• D'Souza J, Hendricks M, Le Guyader S, Subburaju S, Grunewald B, Scholich K, Jesuthasan S. Formation of the retinotectal projection requires Esrom, an ortholog of PAM (protein associated with Myc). Development 2005; 132:247 - 256
   PubMed Web of Science ®Google Scholar