662
Views
10
CrossRef citations to date
0
Altmetric
Article Addendum

Munc13-4*rab27 complex tethers secretory lysosomes at the plasma membrane

, , , , &
Pages 64-67 | Published online: 01 Jan 2012

References

  • Griffiths GM, Tsun A, Stinchcome JC. The immunological synapse: a focal point for endocytosis and exocytosis. J Cell Biol 2010; 189:399 - 406; http://dx.doi.org/10.1083/jcb.201002027; PMID: 20439993
  • Jenkins MR, Tsun A, Stinchcombe JC, Griffiths GM. The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse. Immunity 2009; 31:621 - 31; http://dx.doi.org/10.1016/j.immuni.2009.08.024; PMID: 19833087
  • Higashio H, Nishimura N, Ishizaki H, Miyoshi J, Orita S, Sakane A, et al. Doc2α and munc13-4 regulate Ca2+ dependent secretory lysosome exocytosis in mast cells. J Immunol 2008; 180:4774 - 84; PMID: 18354201
  • Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, et al. Close membrane-membrane proximity induced by Ca2+-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol 2006; 13:209 - 17; http://dx.doi.org/10.1038/nsmb1056; PMID: 16491093
  • Stinchcombe JC, Majorovits E, Bossi G, Fuller S, Griffiths GM. Centrosome polarization delivers secretory granules to the immunological synapse. Nature 2006; 443:462 - 5; http://dx.doi.org/10.1038/nature05071; PMID: 17006514
  • Pachlopnik Schmid J, Cote M, Menager MM, Burgess A, Nehme N, Menasche G, et al. Inherited defects in lymphocyte cytotoxic activity. Immunol Rev 2010; 235:10 - 23; PMID: 20536552
  • Feldmann J, Callebaut I, Raposo G, Certain S, Bacq D, Dumont C, et al. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of Familial Hemophagocytic Lymphohistiocytosis (FHL3). Cell 2003; 115:461 - 73; http://dx.doi.org/10.1016/S0092-8674(03)00855-9; PMID: 14622600
  • Neeft M, Wieffer M, de Jong AS, Negroiu G, Metz CH, van Loon A, et al. Munc13-4 is and effector of rab27a and controls secretion of lysosomes in haematopoietic cells. Mol Biol Cell 2005; 16:731 - 41; http://dx.doi.org/10.1091/mbc.E04-10-0923; PMID: 15548590
  • Ménager MM, Menasche M, Ramoa M, Knapnougel P, Ho CH, Garfa M, et al. Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol 2007; 8:257 - 67; http://dx.doi.org/10.1038/ni1431; PMID: 17237785
  • Wood SM, Meeths M, Chiang SCC, Bechensteen AG, Boelens JJ, Heilmann C, et al. Different NK cell activating receptors preferentially recruit rab27a or munc13-4 to perforin containing granules for cytotoxicity. Blood 2009; 114:4117 - 27; http://dx.doi.org/10.1182/blood-2009-06-225359; PMID: 19704116
  • Elstak ED, Neeft M, Nehme NT, Voortman J, Cheung M, Goodarzifard M, et al. Munc13-4 rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane. Blood 2011; 118:1570 - 8; http://dx.doi.org/10.1182/blood-2011-02-339523; PMID: 21693760
  • Lu J, Machius M, Dulubova I, Dai H, Südhof TC, Tomchick DR, et al. Structural basis for a munc13-1 homodimer to munc13-1/RIM heterodimer switch. PLoS Biol 2006; 4:e192; http://dx.doi.org/10.1371/journal.pbio.0040192; PMID: 16732694
  • Elstak E, de Jong A, van der Sluijs P. A platform for complementation and characterization of familial haemophagocytic lymphohistiocytosis 3 mutations. J Immunol Methods 2011; 365:58 - 66; http://dx.doi.org/10.1016/j.jim.2010.12.009; PMID: 21182842
  • Johnson JL, Hong H, Monfregola J, Kiosses WB, Catz SD. Munc13-4 restricts motility of rab27a expressing vesicles to facilitate lipopolysaccharide-induced priming of exocytosis in neutrophils. J Biol Chem 2011; 286:5647 - 56; http://dx.doi.org/10.1074/jbc.M110.184762; PMID: 21148308
  • Liu D, Meckel T, Long EO. Distinct role of rab27a in granule movement at the plasma membrane and in the cytosol of NK cells. PLoS ONE 2010; 5:e12870; http://dx.doi.org/10.1371/journal.pone.0012870; PMID: 20877725
  • Ménasché G, Menager MM, Lefebre JM, Deutsch E, Althman R, Klambert N, et al. A newly identified isoform of slp2-a associates with rab27a in cytotoxic T cells and participates to cytotoxic T cell degranulation. Blood 2008; 112:5052 - 62; http://dx.doi.org/10.1182/blood-2008-02-141069; PMID: 18812475
  • Holt O, Kanno E, Bossi G, Booth S, Daniele T, Santoro A, et al. Slp1 and slp2-a localize to the plasma membrane of CTL and contribute to secretion at the immunological synapse. Traffic 2008; 9:446 - 57; http://dx.doi.org/10.1111/j.1600-0854.2008.00714.x; PMID: 18266782
  • Betz A, Okamoto M, Benseler F, Brose N. Direct interaction of the rat unc-13 homologue munc13-1 with the N terminus of syntaxin. J Biol Chem 1997; 272:2520 - 6; http://dx.doi.org/10.1074/jbc.272.4.2520; PMID: 8999968
  • Khodthong C, Kabachinski G, James DJ, Martin TFJ. Munc13 homology domain-1 caps/unc31 mediates SNARE binding required for priming vesicle exocytosis. Cell Metab 2011; 14:254 - 63; http://dx.doi.org/10.1016/j.cmet.2011.07.002; PMID: 21803295
  • Ma C, Li W, Xu Y, Rizo J. Munc13 mediates the transition from the closed syntaxin-munc18 complex to the SNARE complex. Nat Struct Mol Biol 2011; 18:542 - 9; http://dx.doi.org/10.1038/nsmb.2047; PMID: 21499244
  • Pei J, Ma C, Rizo J, Grishin NV. Remote homology between munc13 MUN domain and vesicle tethering complexes. J Mol Biol 2009; 391:509 - 17; http://dx.doi.org/10.1016/j.jmb.2009.06.054; PMID: 19563813
  • Hughson FM, Reinisch K. Structure and mechanism in membrane trafficking. Curr Opin Cell Biol 2010; 22:454 - 60; http://dx.doi.org/10.1016/j.ceb.2010.03.011; PMID: 20418086
  • Shin OH, Lu J, Rhee JS, Tomchick DR, Pang ZP, Wojcik SM, et al. Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat Struct Mol Biol 2010; 17:280 - 8; http://dx.doi.org/10.1038/nsmb.1758; PMID: 20154707