Dual channel STED nanoscopy of lytic granules on actin filaments in natural killer cells

References

• Orange JS. Formation and function of the lytic NK-cell immunological synapse. Nat Rev Immunol 2008; 8:713 - 25; http://dx.doi.org/10.1038/nri2381; PMID: 19172692
   PubMed Web of Science ®Google Scholar
• Orange JS, Harris KE, Andzelm MM, Valter MM, Geha RS, Strominger JL. The mature activating natural killer cell immunologic synapse is formed in distinct stages. Proc Natl Acad Sci U S A 2003; 100:14151 - 6; http://dx.doi.org/10.1073/pnas.1835830100; PMID: 14612578
   PubMed Web of Science ®Google Scholar
• Andzelm MM, Chen X, Krzewski K, Orange JS, Strominger JL. Myosin IIA is required for cytolytic granule exocytosis in human NK cells. J Exp Med 2007; 204:2285 - 91; http://dx.doi.org/10.1084/jem.20071143; PMID: 17875677
   PubMed Web of Science ®Google Scholar
• Sanborn KB, Rak GD, Maru SY, Demers K, Difeo A, Martignetti JA, et al. Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse. J Immunol 2009; 182:6969 - 84; http://dx.doi.org/10.4049/jimmunol.0804337; PMID: 19454694
   PubMed Web of Science ®Google Scholar
• Rak GD, Mace EM, Banerjee PP, Svitkina T, Orange JS. Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. PLoS Biol 2011; 9:e1001151; http://dx.doi.org/10.1371/journal.pbio.1001151; PMID: 21931536
   PubMed Web of Science ®Google Scholar
• Brown AC, Oddos S, Dobbie IM, Alakoskela JM, Parton RM, Eissmann P, et al. Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. PLoS Biol 2011; 9:e1001152; http://dx.doi.org/10.1371/journal.pbio.1001152; PMID: 21931537
   PubMed Web of Science ®Google Scholar
• Schermelleh L, Heintzmann R, Leonhardt H. A guide to super-resolution fluorescence microscopy. J Cell Biol 2010; 190:165 - 75; http://dx.doi.org/10.1083/jcb.201002018; PMID: 20643879
   PubMed Web of Science ®Google Scholar
• Hell SW. Far-field optical nanoscopy. Science 2007; 316:1153 - 8; http://dx.doi.org/10.1126/science.1137395; PMID: 17525330
   PubMed Web of Science ®Google Scholar
• Orange JS, Ramesh N, Remold-O’Donnell E, Sasahara Y, Koopman L, Byrne M, et al. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses. Proc Natl Acad Sci U S A 2002; 99:11351 - 6; http://dx.doi.org/10.1073/pnas.162376099; PMID: 12177428
   PubMed Web of Science ®Google Scholar
• Wulfing C, Purtic B, Klem J, Schatzle JD. Stepwise cytoskeletal polarization as a series of checkpoints in innate but not adaptive cytolytic killing. Proc Natl Acad Sci U S A 2003; 100:7767 - 72; http://dx.doi.org/10.1073/pnas.1336920100; PMID: 12802007
   PubMed Web of Science ®Google Scholar
• Valitutti S, Dessing M, Aktories K, Gallati H, Lanzavecchia A. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J Exp Med 1995; 181:577 - 84; http://dx.doi.org/10.1084/jem.181.2.577; PMID: 7836913
   PubMed Web of Science ®Google Scholar
• Wülfing C, Sjaastad MD, Davis MM. Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels. Proc Natl Acad Sci U S A 1998; 95:6302 - 7; http://dx.doi.org/10.1073/pnas.95.11.6302; PMID: 9600960
   PubMed Web of Science ®Google Scholar
• Stinchcombe JC, Bossi G, Booth S, Griffiths GM. The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity 2001; 15:751 - 61; http://dx.doi.org/10.1016/S1074-7613(01)00234-5; PMID: 11728337
   PubMed Web of Science ®Google Scholar
• Stinchcombe JC, Majorovits E, Bossi G, Fuller S, Griffiths GM. Centrosome polarization delivers secretory granules to the immunological synapse. Nature 2006; 443:462 - 5; http://dx.doi.org/10.1038/nature05071; PMID: 17006514
   PubMed Web of Science ®Google Scholar