1,169
Views
70
CrossRef citations to date
0
Altmetric
Mini Review

Mitogen-activated protein kinases and Wnt/β-catenin signaling

molecular conversations among signaling pathways

&
Pages 46-49 | Received 28 Nov 2008, Accepted 01 Dec 2008, Published online: 01 Feb 2009

References

  • Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK and p38 protein kinases. Science 2002; 298:1911 - 1912
  • Dong C, Davis RJ, Flavell RA. MAP kinases in the immune response. Annu Rev Immunol 2002; 20:55 - 72
  • Logan CY, Nusse R. The Wnt signalling pathway in development and disease. Annu Rev Cell Dev Biol 2004; 20:781 - 810
  • Moon RT, Bowerman B, Boutros M, Perrimon N. The promise and perils of Wnt signalling through beta-catenin. Science 2002; 296:1644 - 1646
  • Moon RT, Kohn AD, De Ferrari GV, Kaykas A. WNT and beta-catenin signalling: diseases and therapies. Nat Rev Genet 2004; 5:691 - 701
  • Polakis P. The many ways of Wnt in cancer. Curr Opin Genet Dev 2007; 17:45 - 51
  • Bhanot P, Brink M, Samos CH, Hsieh JC, Wang Y, Macke JP, Andrew D, Nathans J, Nusse R. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 1996; 382:225 - 230
  • Liu T, DeCostanzo AJ, Liu X, Wang Hy, Hallagan S, Moon RT, Malbon CC. G protein signalling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway. Science 2001; 292:1718 - 1722
  • Liu T, Liu X, Wang H, Moon RT, Malbon CC. Activation of rat frizzled-1 promotes Wnt signalling and differentiation of mouse F9 teratocarcinoma cells via pathways that require Galpha(q) and Galpha(o) function. J Biol Chem 1999; 274:33539 - 33544
  • Bikkavilli RK, Feigin ME, Malbon CC. Galphao mediates WNT-JNK signalling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells. J Cell Sci 2008; 121:234 - 245
  • Habas R, Dawid IB, He X. Coactivation of Rac and Rho by Wnt/Frizzled signalling is required for vertebrate gastrulation. Genes Dev 2003; 17:295 - 309
  • Mlodzik M. Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?. Trends Genet 2002; 18:564 - 571
  • Ma L, Wang HY. Mitogen-activated protein kinase p38 regulates the Wnt/cyclic GMP/Ca2+ non-canonical pathway. J Biol Chem 2007; 282:28980 - 28990
  • Ma L, Wang HY. Suppression of cyclic GMP-dependent protein kinase is essential to the Wnt/cGMP/Ca2+ pathway. J Biol Chem 2006; 281:30990 - 31001
  • Behrens J, von Kries JP, Kühl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996; 382:638 - 642
  • Molenaar M, van de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, Korinek V, Roose J, Destrée O, Clevers H. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 1996; 86:391 - 399
  • Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996; 87:159 - 170
  • Rubinfeld B, Robbins P, El-Gamil M, Albert I, Porfiri E, Polakis P. Stabilization of beta-catenin by genetic defects in melanoma cell lines. Science 1997; 275:1790 - 1792
  • Chan EF, Gat U, McNiff JM, Fuchs E. A common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet 1999; 21:410 - 413
  • Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW. Activation of beta-catenin-Tcf signalling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275:1787 - 1790
  • Sparks AB, Morin PJ, Vogelstein B, Kinzler KW. Mutational analysis of the APC/betacatenin/Tcf pathway in colorectal cancer. Cancer Res 1998; 58:1130 - 1134
  • Martin-Blanco E. p38 MAPK signalling cascades: ancient roles and new functions. BioEssays 2000; 22:637 - 645
  • Bikkavilli RK, Feigin ME, Malbon CC. p38 mitogen-activated protein kinase regulates canonical Wnt-{beta}-catenin signalling by inactivation of GSK3{beta}. J Cell Sci 2008; 121:3598 - 3607
  • Chang J, Sonoyama W, Wang Z, Jin Q, Zhang C, Krebsbach PH, Giannobile W, Shi S, Wang CY. Noncanonical Wnt-4 signalling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK. J Biol Chem 2007; 282:30938 - 30948
  • Caverzasio J, Manen D. Essential role of Wnt3a-mediated activation of mitogen-activated protein kinase p38 for the stimulation of alkaline phosphatase activity and matrix mineralization in C3H10T1/2 mesenchymal cells. Endocrinology 2007; 148:5323 - 5330
  • Thornton TM, Pedraza-Alva G, Deng B, Wood CD, Aronshtam A, Clements JL, Sabio G, Davis RJ, Matthews DE, Doble B, Rincon M. Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation. Science 2008; 320:667 - 670
  • Shi CS, Huang NN, Harrison K, Han SB, Kehrl JH. The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signalling in B lymphocytes. Mol Cell Biol 2006; 26:6511 - 6521
  • Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP, Li L. Nuclear Dvl, c-Jun, beta-catenin and TCF form a complex leading to stabilization of beta-catenin-TCF interaction. J Cell Biol 2008; 180:1087 - 1100
  • Nateri AS, Spencer-Dene B, Behrens A. Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development. Nature 2005; 437:281 - 285
  • Rivat C, Le Floch N, Sabbah M, Teyrol I, Redeuilh G, Bruyneel E, Mareel M, Matrisian LM, Crawford HC, Gespach C, Attoub S. Synergistic cooperation between the AP-1 and LEF-1 transcription factors in activation of the matrilysin promoter by the src oncogene: implications in cellular invasion. FASEB J 2003; 17:1721 - 1723
  • Yoon S, Seger R. The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 2006; 24:21 - 44
  • Kim SE, Choi KY. EGF receptor is involved in WNT3a-mediated proliferation and motility of NIH3T3 cells via ERK pathway activation. Cell Signal 2007; 19:1554 - 1564
  • Yun MS, Kim SE, Jeon SH, Lee JS, Choi KY. Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation. J Cell Sci 2005; 118:313 - 322
  • Lee YN, Gao Y, Wang HY. Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2 and -3. Cell Signal 2008; 20:443 - 452
  • Etheridge SL, Ray S, Li S, Hamblet NS, Lijam N, Tsang M, Greer J, Kardos N, Wang J, Sussman DJ, Chen P, Wynshaw-Boris A. Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea and neural tube development. PLoS Genet 2008; 4