532
Views
16
CrossRef citations to date
0
Altmetric
Article Addendum

Death or secretion? The demise of a plausible assumption about CSF-tau in Alzheimer Disease?

&
Pages 623-626 | Published online: 01 Nov 2012

References

  • Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, et al. Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J Biol Chem 2012; 287:3842 - 9; http://dx.doi.org/10.1074/jbc.M111.277061; PMID: 22057275
  • Delacourte A, David JP, Sergeant N, Buée L, Wattez A, Vermersch P, et al. The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer’s disease. Neurology 1999; 52:1158 - 65; http://dx.doi.org/10.1212/WNL.52.6.1158; PMID: 10214737
  • Lee VM, Goedert M, Trojanowski JQ. Neurodegenerative tauopathies. Annu Rev Neurosci 2001; 24:1121 - 59; http://dx.doi.org/10.1146/annurev.neuro.24.1.1121; PMID: 11520930
  • Goedert M, Jakes R. Mutations causing neurodegenerative tauopathies. Biochim Biophys Acta 2005; 1739:240 - 50; http://dx.doi.org/10.1016/j.bbadis.2004.08.007; PMID: 15615642
  • Caceres A, Kosik KS. Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons. Nature 1990; 343:461 - 3; http://dx.doi.org/10.1038/343461a0; PMID: 2105469
  • Hall GF. The biology and pathobiology of tau protein. In: The Cytoskeleton and Human Disease. Kavallaris M (ed), Springer Verlag, 2012; In press.
  • Lee G, Thangavel R, Sharma VM, Litersky JM, Bhaskar K, Fang SM, et al. Phosphorylation of tau by fyn: implications for Alzheimer’s disease. J Neurosci 2004; 24:2304 - 12; http://dx.doi.org/10.1523/JNEUROSCI.4162-03.2004; PMID: 14999081
  • Park SY, Ferreira A. The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration. J Neurosci 2005; 25:5365 - 75; http://dx.doi.org/10.1523/JNEUROSCI.1125-05.2005; PMID: 15930385
  • Amadoro G, Ciotti MT, Costanzi M, Cestari V, Calissano P, Canu N. NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation. Proc Natl Acad Sci U S A 2006; 103:2892 - 7; http://dx.doi.org/10.1073/pnas.0511065103; PMID: 16477009
  • Calissano P, Matrone C, Amadoro G. Apoptosis and in vitro Alzheimer disease neuronal models. Commun Integr Biol 2009; 2:163 - 9; PMID: 19513272
  • Ittner LM, Ke YD, Delerue F, Bi M, Gladbach A, van Eersel J, et al. Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer’s disease mouse models. Cell 2010; 142:387 - 97; http://dx.doi.org/10.1016/j.cell.2010.06.036; PMID: 20655099
  • King ME, Kan HM, Baas PW, Erisir A, Glabe CG, Bloom GS. Tau-dependent microtubule disassembly initiated by prefibrillar beta-amyloid. J Cell Biol 2006; 175:541 - 6; http://dx.doi.org/10.1083/jcb.200605187; PMID: 17101697
  • Rapoport M, Dawson HN, Binder LI, Vitek MP, Ferreira A. Tau is essential to beta -amyloid-induced neurotoxicity. Proc Natl Acad Sci U S A 2002; 99:6364 - 9; http://dx.doi.org/10.1073/pnas.092136199; PMID: 11959919
  • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991; 82:239 - 59; http://dx.doi.org/10.1007/BF00308809; PMID: 1759558
  • Su JH, Deng G, Cotman CW. Transneuronal degeneration in the spread of Alzheimer’s disease pathology: immunohistochemical evidence for the transmission of tau hyperphosphorylation. Neurobiol Dis 1997; 4:365 - 75; http://dx.doi.org/10.1006/nbdi.1997.0164; PMID: 9440125
  • Armstrong RA, Cairns NJ, Lantos PL. What does the study of the spatial patterns of pathological lesions tell us about the pathogenesis of neurodegenerative disorders?. Neuropathology 2001; 21:1 - 12; http://dx.doi.org/10.1046/j.1440-1789.2001.00373.x; PMID: 11304036
  • Frost B, Jacks RL, Diamond MI. Propagation of tau misfolding from the outside to the inside of a cell. J Biol Chem 2009; 284:12845 - 52; http://dx.doi.org/10.1074/jbc.M808759200; PMID: 19282288
  • Kim W, Lee S, Hall GF. Secretion of human tau fragments resembling CSF-tau in Alzheimer’s disease is modulated by the presence of the exon 2 insert. FEBS Lett 2010; 584:3085 - 8; http://dx.doi.org/10.1016/j.febslet.2010.05.042; PMID: 20553717
  • Kim W, Lee S, Jung C, Ahmed A, Lee G, Hall GF. Interneuronal transfer of human tau between Lamprey central neurons in situ. J Alzheimers Dis 2010; 19:647 - 64; PMID: 20110609
  • Guo JL, Lee VM. Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles. J Biol Chem 2011; 286:15317 - 31; http://dx.doi.org/10.1074/jbc.M110.209296; PMID: 21372138
  • Hall GF, Lee S, Yao J. Neurofibrillary degeneration can be arrested in an in vivo cellular model of human tauopathy by application of a compound which inhibits tau filament formation in vitro. J Mol Neurosci 2002; 19:253 - 60; http://dx.doi.org/10.1385/JMN:19:3:251; PMID: 12540050
  • Lee S, Kim W, Li Z, Hall GF. Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model. In: Animal Models of Alzheimer's Disease. J Alz Dis 2011; In press (Hindawi ISBN: 978-953-307-797-0).
  • Aguzzi A, Rajendran L. The transcellular spread of cytosolic amyloids, prions, and prionoids. Neuron 2009; 64:783 - 90; http://dx.doi.org/10.1016/j.neuron.2009.12.016; PMID: 20064386
  • Novak P, Prcina M, Kontsekova E. Tauons and prions: infamous cousins?. J Alzheimers Dis 2011; 26:413 - 30; PMID: 21694453
  • Hall GF. What is the common link between protein aggregation and interneuronal lesion propagation in neurodegenerative disease? In: Neurodegenerative Diseases - Processes, Prevention, Protection and Monitoring. Chang R (ed), 2011; pp 1-17.
  • Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol 2009; 11:909 - 13; http://dx.doi.org/10.1038/ncb1901; PMID: 19503072
  • Liu L, Drouet V, Wu JW, Witter MP, Small SA, Clelland C, et al. Trans-synaptic spread of tau pathology in vivo. PLoS One 2012; 7:e31302; http://dx.doi.org/10.1371/journal.pone.0031302; PMID: 22312444
  • de Calignon A, Polydoro M, Suárez-Calvet M, William C, Adamowicz DH, Kopeikina KJ, et al. Propagation of tau pathology in a model of early Alzheimer’s disease. Neuron 2012; 73:685 - 97; http://dx.doi.org/10.1016/j.neuron.2011.11.033; PMID: 22365544
  • Gómez-Ramos A, Díaz-Hernández M, Rubio A, Miras-Portugal MT, Avila J. Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells. Mol Cell Neurosci 2008; 37:673 - 81; http://dx.doi.org/10.1016/j.mcn.2007.12.010; PMID: 18272392
  • Hall GF, Patuto BA. Is tau ready for admission to the prion club?. Prion 2012; 6:223 - 33; http://dx.doi.org/10.4161/pri.19912; PMID: 22561167
  • Hall GF, Hasan SK. Tau secretion, tau toxicity and the biogenesis of CSF-tau – implications for how we view AD. In review
  • Seppälä TT, Koivisto AM, Hartikainen P, Helisalmi S, Soininen H, Herukka S-K. Longitudinal changes of CSF biomarkers in Alzheimer’s disease. J Alzheimers Dis 2011; 25:583 - 94; PMID: 21460434
  • Johnson GV, Seubert P, Cox TM, Motter R, Brown JP, Galasko D. The tau protein in human cerebrospinal fluid in Alzheimer’s disease consists of proteolytically derived fragments. J Neurochem 1997; 68:430 - 3; http://dx.doi.org/10.1046/j.1471-4159.1997.68010430.x; PMID: 8978756
  • Sjögren M, Rosengren L, Minthon L, Davidsson P, Blennow K, Wallin A. Cytoskeleton proteins in CSF distinguish frontotemporal dementia from AD. Neurology 2000; 54:1960 - 4; http://dx.doi.org/10.1212/WNL.54.10.1960; PMID: 10822437
  • van Harten AC, Kester MI, Visser PJ, Blankenstein MA, Pijnenburg YA, van der Flier WM, et al. Tau and p-tau as CSF biomarkers in dementia: a meta-analysis. Clin Chem Lab Med 2011; 49:353 - 66; http://dx.doi.org/10.1515/cclm.2011.086; PMID: 21342021
  • Yamada K, Cirrito JR, Stewart FR, Jiang H, Finn MB, Holmes BB, et al. In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. J Neurosci 2011; 31:13110 - 7; http://dx.doi.org/10.1523/JNEUROSCI.2569-11.2011; PMID: 21917794
  • Barten DM, Cadelina GW, Hoque N, DeCarr LB, Guss VL, Yang L, et al. Tau transgenic mice as models for cerebrospinal fluid tau biomarkers. J Alzheimers Dis 2011; 24:Suppl 2 127 - 41; PMID: 21422517
  • Arai H, Terajima M, Miura M, Higuchi S, Muramatsu T, Machida N, et al. Tau in cerebrospinal fluid: a potential diagnostic marker in Alzheimer’s disease. Ann Neurol 1995; 38:649 - 52; http://dx.doi.org/10.1002/ana.410380414; PMID: 7574462
  • Tato RE, Frank A, Hernanz A. Tau protein concentrations in cerebrospinal fluid of patients with dementia of the Alzheimer type. J Neurol Neurosurg Psychiatry 1995; 59:280 - 3; http://dx.doi.org/10.1136/jnnp.59.3.280; PMID: 7545739
  • Bancher C, Brunner C, Lassmann H, Budka H, Jellinger K, Wiche G, et al. Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer’s disease. Brain Res 1989; 477:90 - 9; http://dx.doi.org/10.1016/0006-8993(89)91396-6; PMID: 2495152
  • Braak E, Braak H, Mandelkow EM. A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol 1994; 87:554 - 67; http://dx.doi.org/10.1007/BF00293315; PMID: 7522386
  • Morsch R, Simon W, Coleman PD. Neurons may live for decades with neurofibrillary tangles. J Neuropathol Exp Neurol 1999; 58:188 - 97; http://dx.doi.org/10.1097/00005072-199902000-00008; PMID: 10029101
  • Hesse C, Rosengren L, Andreasen N, Davidsson P, Vanderstichele H, Vanmechelen E, et al. Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke. Neurosci Lett 2001; 297:187 - 90; http://dx.doi.org/10.1016/S0304-3940(00)01697-9; PMID: 11137759
  • Palmio J, Suhonen J, Keränen T, Hulkkonen J, Peltola J, Pirttilä T. Cerebrospinal fluid tau as a marker of neuronal damage after epileptic seizure. Seizure 2009; 18:474 - 7; http://dx.doi.org/10.1016/j.seizure.2009.04.006; PMID: 19428269
  • Siman R, McIntosh TK, Soltesz KM, Chen Z, Neumar RW, Roberts VL. Proteins released from degenerating neurons are surrogate markers for acute brain damage. Neurobiol Dis 2004; 16:311 - 20; http://dx.doi.org/10.1016/j.nbd.2004.03.016; PMID: 15193288
  • Nickel W. Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells. Traffic 2005; 6:607 - 14; http://dx.doi.org/10.1111/j.1600-0854.2005.00302.x; PMID: 15998317
  • Chen C, Shi Q, Zhang BY, Wang GR, Zhou W, Gao C, et al. The prepared tau exon-specific antibodies revealed distinct profiles of tau in CSF of the patients with Creutzfeldt-Jakob disease. PLoS One 2010; 5:e11886; http://dx.doi.org/10.1371/journal.pone.0011886; PMID: 20686702
  • Tosun D, Schuff N, Truran-Sacrey D, Shaw LM, Trojanowski JQ, Aisen P, et al, Alzheimer’s Disease Neuroimaging Initiative. Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study. Neurobiol Aging 2010; 31:1340 - 54; http://dx.doi.org/10.1016/j.neurobiolaging.2010.04.030; PMID: 20570401
  • Solé-Padullés C, Lladó A, Bartrés-Faz D, Fortea J, Sánchez-Valle R, Bosch B, et al. Association between cerebrospinal fluid tau and brain atrophy is not related to clinical severity in the Alzheimer’s disease continuum. Psychiatry Res 2011; 192:140 - 6; http://dx.doi.org/10.1016/j.pscychresns.2010.12.001; PMID: 21546220
  • Snow J. On the Mode of Communication of Cholera. 2nd ed, London, J. Churchill, 1855, pp 162.