Need an ESCRT for autophagosomal maturation?

References

• Reggiori F, Klionsky DJ. Autophagy in the eukaryotic cell. Eukaryot Cell 2002; 1:11 - 21; http://dx.doi.org/10.1128/EC.01.1.11-21.2002; PMID: 12455967
   PubMed Web of Science ®Google Scholar
• Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun 2004; 313:453 - 8; http://dx.doi.org/10.1016/j.bbrc.2003.07.023; PMID: 14684184
   PubMed Web of Science ®Google Scholar
• Hayashi-Nishino M, Fujita N, Noda T, Yamaguchi A, Yoshimori T, Yamamoto A. A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation. Nat Cell Biol 2009; 11:1433 - 7; http://dx.doi.org/10.1038/ncb1991; PMID: 19898463
   PubMed Web of Science ®Google Scholar
• Ylä-Anttila P, Vihinen H, Jokitalo E, Eskelinen EL. 3D tomography reveals connections between the phagophore and endoplasmic reticulum. Autophagy 2009; 5:1180 - 5; http://dx.doi.org/10.4161/auto.5.8.10274; PMID: 19855179
   PubMed Web of Science ®Google Scholar
• Hailey DW, Rambold AS, Satpute-Krishnan P, Mitra K, Sougrat R, Kim PK, et al. Mitochondria supply membranes for autophagosome biogenesis during starvation. Cell 2010; 141:656 - 67; http://dx.doi.org/10.1016/j.cell.2010.04.009; PMID: 20478256
   PubMed Web of Science ®Google Scholar
• Ravikumar B, Moreau K, Jahreiss L, Puri C, Rubinsztein DC. Plasma membrane contributes to the formation of pre-autophagosomal structures. Nat Cell Biol 2010; 12:747 - 57; http://dx.doi.org/10.1038/ncb2078; PMID: 20639872
   PubMed Web of Science ®Google Scholar
• Tooze SA, Yoshimori T. The origin of the autophagosomal membrane. Nat Cell Biol 2010; 12:831 - 5; http://dx.doi.org/10.1038/ncb0910-831; PMID: 20811355
   PubMed Web of Science ®Google Scholar
• Mizushima N. Autophagy: process and function. Genes Dev 2007; 21:2861 - 73; http://dx.doi.org/10.1101/gad.1599207; PMID: 18006683
   PubMed Web of Science ®Google Scholar
• Ichimura Y, Kirisako T, Takao T, Satomi Y, Shimonishi Y, Ishihara N, et al. A ubiquitin-like system mediates protein lipidation. Nature 2000; 408:488 - 92; http://dx.doi.org/10.1038/35044114; PMID: 11100732
   PubMed Web of Science ®Google Scholar
• Kirisako T, Ichimura Y, Okada H, Kabeya Y, Mizushima N, Yoshimori T, et al. The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 2000; 151:263 - 76; http://dx.doi.org/10.1083/jcb.151.2.263; PMID: 11038174
   PubMed Web of Science ®Google Scholar
• Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008; 4:151 - 75; PMID: 18188003
   PubMed Web of Science ®Google Scholar
• Gruenberg J, Stenmark H. The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol 2004; 5:317 - 23; http://dx.doi.org/10.1038/nrm1360; PMID: 15071556
   PubMed Web of Science ®Google Scholar
• Piper RC, Katzmann DJ. Biogenesis and function of multivesicular bodies. Annu Rev Cell Dev Biol 2007; 23:519 - 47; http://dx.doi.org/10.1146/annurev.cellbio.23.090506.123319; PMID: 17506697
   PubMed Web of Science ®Google Scholar
• Berg TO, Fengsrud M, Strømhaug PE, Berg T, Seglen PO. Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes. J Biol Chem 1998; 273:21883 - 92; http://dx.doi.org/10.1074/jbc.273.34.21883; PMID: 9705327
   PubMed Web of Science ®Google Scholar
• Gordon PB, Seglen PO. Prelysosomal convergence of autophagic and endocytic pathways. Biochem Biophys Res Commun 1988; 151:40 - 7; http://dx.doi.org/10.1016/0006-291X(88)90556-6; PMID: 3126737
   PubMed Web of Science ®Google Scholar
• Bache KG, Brech A, Mehlum A, Stenmark H. Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes. J Cell Biol 2003; 162:435 - 42; http://dx.doi.org/10.1083/jcb.200302131; PMID: 12900395
   PubMed Web of Science ®Google Scholar
• Katzmann DJ, Stefan CJ, Babst M, Emr SD. Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J Cell Biol 2003; 162:413 - 23; http://dx.doi.org/10.1083/jcb.200302136; PMID: 12900393
   PubMed Web of Science ®Google Scholar
• Lu Q, Hope LW, Brasch M, Reinhard C, Cohen SN. TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc Natl Acad Sci U S A 2003; 100:7626 - 31; http://dx.doi.org/10.1073/pnas.0932599100; PMID: 12802020
   PubMed Web of Science ®Google Scholar
• Im YJ, Hurley JH. Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex. Dev Cell 2008; 14:902 - 13; http://dx.doi.org/10.1016/j.devcel.2008.04.004; PMID: 18539118
   PubMed Web of Science ®Google Scholar
• Wollert T, Hurley JH. Molecular mechanism of multivesicular body biogenesis by ESCRT complexes. Nature 2010; 464:864 - 9; http://dx.doi.org/10.1038/nature08849; PMID: 20305637
   PubMed Web of Science ®Google Scholar
• Babst M. A protein’s final ESCRT. Traffic 2005; 6:2 - 9; http://dx.doi.org/10.1111/j.1600-0854.2004.00246.x; PMID: 15569240
   PubMed Web of Science ®Google Scholar
• Hurley JH, Emr SD. The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu Rev Biophys Biomol Struct 2006; 35:277 - 98; http://dx.doi.org/10.1146/annurev.biophys.35.040405.102126; PMID: 16689637
   PubMedGoogle Scholar
• Stefani F, Zhang L, Taylor S, Donovan J, Rollinson S, Doyotte A, et al. UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting. Curr Biol 2011; 21:1245 - 50; http://dx.doi.org/10.1016/j.cub.2011.06.028; PMID: 21757351
   PubMed Web of Science ®Google Scholar
• Slagsvold T, Pattni K, Malerød L, Stenmark H. Endosomal and non-endosomal functions of ESCRT proteins. Trends Cell Biol 2006; 16:317 - 26; http://dx.doi.org/10.1016/j.tcb.2006.04.004; PMID: 16716591
   PubMed Web of Science ®Google Scholar
• Djeddi A, Michelet X, Culetto E, Alberti A, Barois N, Legouis R. Induction of autophagy in ESCRT mutants is an adaptive response for cell survival in C. elegans. J Cell Sci 2012; 125:685 - 94; http://dx.doi.org/10.1242/jcs.091702; PMID: 22389403
   PubMed Web of Science ®Google Scholar
• Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, et al. Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease. J Cell Biol 2007; 179:485 - 500; http://dx.doi.org/10.1083/jcb.200702115; PMID: 17984323
   PubMed Web of Science ®Google Scholar
• Lee JA, Beigneux A, Ahmad ST, Young SG, Gao FB. ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr Biol 2007; 17:1561 - 7; http://dx.doi.org/10.1016/j.cub.2007.07.029; PMID: 17683935
   PubMed Web of Science ®Google Scholar
• Rusten TE, Filimonenko M, Rodahl LM, Stenmark H, Simonsen A. ESCRTing autophagic clearance of aggregating proteins. Autophagy 2008; 4:233 - 6; PMID: 18204305
   PubMed Web of Science ®Google Scholar
• Tamai K, Tanaka N, Nara A, Yamamoto A, Nakagawa I, Yoshimori T, et al. Role of Hrs in maturation of autophagosomes in mammalian cells. Biochem Biophys Res Commun 2007; 360:721 - 7; http://dx.doi.org/10.1016/j.bbrc.2007.06.105; PMID: 17624298
   PubMed Web of Science ®Google Scholar
• Parkinson N, Ince PG, Smith MO, Highley R, Skibinski G, Andersen PM, et al, MRC Proteomics in ALS Study, FReJA Consortium. ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). Neurology 2006; 67:1074 - 7; http://dx.doi.org/10.1212/01.wnl.0000231510.89311.8b; PMID: 16807408
   PubMed Web of Science ®Google Scholar
• Skibinski G, Parkinson NJ, Brown JM, Chakrabarti L, Lloyd SL, Hummerich H, et al. Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. Nat Genet 2005; 37:806 - 8; http://dx.doi.org/10.1038/ng1609; PMID: 16041373
   PubMed Web of Science ®Google Scholar
• Talbot K, Ansorge O. Recent advances in the genetics of amyotrophic lateral sclerosis and frontotemporal dementia: common pathways in neurodegenerative disease. Hum Mol Genet 2006; 15:Spec No 2 R182 - 7; http://dx.doi.org/10.1093/hmg/ddl202; PMID: 16987882
   PubMed Web of Science ®Google Scholar
• Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, et al. ESCRTs and Fab1 regulate distinct steps of autophagy. Curr Biol 2007; 17:1817 - 25; http://dx.doi.org/10.1016/j.cub.2007.09.032; PMID: 17935992
   PubMed Web of Science ®Google Scholar
• Alberti A, Michelet X, Djeddi A, Legouis R. The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans. Autophagy 2010; 6:622 - 33; http://dx.doi.org/10.4161/auto.6.5.12252; PMID: 20523114
   PubMed Web of Science ®Google Scholar
• Michelet X, Alberti A, Benkemoun L, Roudier N, Lefebvre C, Legouis R. The ESCRT-III protein CeVPS-32 is enriched in domains distinct from CeVPS-27 and CeVPS-23 at the endosomal membrane of epithelial cells. Biol Cell 2009; 101:599 - 615; http://dx.doi.org/10.1042/BC20090025; PMID: 19432559
   PubMed Web of Science ®Google Scholar
• Michelet X, Djeddi A, Legouis R. Developmental and cellular functions of the ESCRT machinery in pluricellular organisms. Biol Cell 2010; 102:191 - 202; http://dx.doi.org/10.1042/BC20090145; PMID: 20059450
   PubMed Web of Science ®Google Scholar
• Roudier N, Lefebvre C, Legouis R. CeVPS-27 is an endosomal protein required for the molting and the endocytic trafficking of the low-density lipoprotein receptor-related protein 1 in Caenorhabditis elegans. Traffic 2005; 6:695 - 705; http://dx.doi.org/10.1111/j.1600-0854.2005.00309.x; PMID: 15998324
   PubMed Web of Science ®Google Scholar
• Eskelinen EL. Fine structure of the autophagosome. Methods Mol Biol 2008; 445:11 - 28; http://dx.doi.org/10.1007/978-1-59745-157-4_2; PMID: 18425441
   PubMedGoogle Scholar
• Liou W, Geuze HJ, Geelen MJ, Slot JW. The autophagic and endocytic pathways converge at the nascent autophagic vacuoles. J Cell Biol 1997; 136:61 - 70; http://dx.doi.org/10.1083/jcb.136.1.61; PMID: 9008703
   PubMed Web of Science ®Google Scholar
• Tooze J, Hollinshead M, Ludwig T, Howell K, Hoflack B, Kern H. In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome. J Cell Biol 1990; 111:329 - 45; http://dx.doi.org/10.1083/jcb.111.2.329; PMID: 2166050
   PubMed Web of Science ®Google Scholar
• Fader CM, Sanchez DG, Mestre MB, Colombo MI. TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways. Biochim Biophys Acta 2009; 1793:1901-16.
   Google Scholar
• Dunn WA Jr.. Studies on the mechanisms of autophagy: maturation of the autophagic vacuole. J Cell Biol 1990; 110:1935 - 45; http://dx.doi.org/10.1083/jcb.110.6.1935; PMID: 2161853
   PubMed Web of Science ®Google Scholar
• Moreau K, Ravikumar B, Renna M, Puri C, Rubinsztein DC. Autophagosome precursor maturation requires homotypic fusion. Cell 2011; 146:303 - 17; http://dx.doi.org/10.1016/j.cell.2011.06.023; PMID: 21784250
   PubMed Web of Science ®Google Scholar
• Nair U, Jotwani A, Geng J, Gammoh N, Richerson D, Yen WL, et al. SNARE proteins are required for macroautophagy. Cell 2011; 146:290 - 302; http://dx.doi.org/10.1016/j.cell.2011.06.022; PMID: 21784249
   PubMed Web of Science ®Google Scholar
• Sahu R, Kaushik S, Clement CC, Cannizzo ES, Scharf B, Follenzi A, et al. Microautophagy of cytosolic proteins by late endosomes. Dev Cell 2011; 20:131 - 9; http://dx.doi.org/10.1016/j.devcel.2010.12.003; PMID: 21238931
   PubMed Web of Science ®Google Scholar
• Dobrowolski R, De Robertis EM. Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles. Nat Rev Mol Cell Biol 2012; 13:53 - 60; PMID: 22108513
   PubMed Web of Science ®Google Scholar
• Lemmon SK, Traub LM. Sorting in the endosomal system in yeast and animal cells. Curr Opin Cell Biol 2000; 12:457 - 66; http://dx.doi.org/10.1016/S0955-0674(00)00117-4; PMID: 10873832
   PubMed Web of Science ®Google Scholar
• Bruns C, McCaffery JM, Curwin AJ, Duran JM, Malhotra V. Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion. J Cell Biol 2011; 195:979 - 92; http://dx.doi.org/10.1083/jcb.201106098; PMID: 22144692
   PubMed Web of Science ®Google Scholar
• Shimobayashi M, Takematsu H, Eiho K, Yamane Y, Kozutsumi Y. Identification of Ypk1 as a novel selective substrate for nitrogen starvation-triggered proteolysis requiring autophagy system and endosomal sorting complex required for transport (ESCRT) machinery components. J Biol Chem 2010; 285:36984 - 94; http://dx.doi.org/10.1074/jbc.M110.119180; PMID: 20855891
   PubMed Web of Science ®Google Scholar