DVL as a scaffold protein capturing classical GPCRs

References

• Malaterre J, Ramsay RG, Mantamadiotis T. Wnt-Frizzled signalling and the many paths to neural development and adult brain homeostasis. Front Biosci 2007; 12:4 - 7
   Web of Science ®Google Scholar
• Luo J, Chen J, Deng ZL, Luo X, Song WX, Sharff KA, et al. Wnt signaling and human diseases: what are the therapeutic implications?. Lab Invest 2007; 87:97 - 103
   PubMed Web of Science ®Google Scholar
• Schulte G, Bryja V. The Frizzled family of unconventional G-protein-coupled receptors. Trends Pharmacol Sci 2007; 28:518 - 525
   PubMed Web of Science ®Google Scholar
• Shevtsov SP, Haq S, Force T. Activation of beta-catenin signaling pathways by classical G-protein-coupled receptors: mechanisms and consequences in cycling and non-cycling cells. Cell Cycle 2006; 5:2295 - 2300
   PubMed Web of Science ®Google Scholar
• Haq S, Michael A, Andreucci M, Bhattacharya K, Dotto P, Walters B, et al. Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth. Proc Natl Acad Sci USA 2003; 100:4610 - 4615
   PubMed Web of Science ®Google Scholar
• Yang M, Zhong WW, Srivastava N, Slavin A, Yang J, Hoey T, et al. G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway. Proc Natl Acad Sci USA 2005; 102:6027 - 6032
   PubMed Web of Science ®Google Scholar
• Castellone MD, Teramoto H, Williams BO, Druey KM, Gutkind JS. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. Science 2005; 310:1504 - 1510
   PubMed Web of Science ®Google Scholar
• Force T, Woulfe K, Koch WJ, Kerkela R. Molecular scaffolds regulate bidirectional crosstalk between Wnt and classical seven-transmembrane-domain receptor signaling pathways. Sci STKE 2007; 2007:41
   Google Scholar
• Turm H, Maoz M, Katz V, Yin YJ, Offermanns S, Bar-Shavit R. Protease-activated receptor-1 (PAR1) acts via a novel Galpha13-dishevelled axis to stabilize beta-catenin levels. J Biol Chem 2010; 285:15137 - 15148
   PubMed Web of Science ®Google Scholar
• Romero G, Sneddon WB, Yang Y, Wheeler D, Blair HC, Friedman PA. Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis. J Biol Chem 2010; 285:14756 - 14763
   PubMed Web of Science ®Google Scholar
• Fujino H, West KA, Regan JW. Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. J Biol Chem 2002; 277:2614 - 2619
   PubMed Web of Science ®Google Scholar
• Alessi DR, Cohen P. Mechanism of activation and function of protein kinase B. Curr Opin Genet Dev 1998; 8:55 - 62
   PubMed Web of Science ®Google Scholar
• Stambolic V, Mak TW, Woodgett JR. Modulation of cellular apoptotic potential: contributions to oncogenesis. Oncogene 1999; 18:6094 - 6103
   PubMed Web of Science ®Google Scholar
• Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes Dev 1999; 13:2905 - 2927
   PubMed Web of Science ®Google Scholar
• Guillermet-Guibert J, Bjorklof K, Salpekar A, Gonella C, Ramadani F, Bilancio A, et al. The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma. Proc Natl Acad Sci USA 2008; 105:8292 - 8297
   PubMed Web of Science ®Google Scholar
• Yin YJ, Salah Z, Maoz M, Ram SC, Ochayon S, Neufeld G, et al. Oncogenic transformation induces tumor angiogenesis: a role for PAR1 activation. FASEB J 2003; 17:163 - 174
   PubMed Web of Science ®Google Scholar
• Wang P, DeFea KA. Protease-activated receptor-2 simultaneously directs beta-arrestin-1-dependent inhibition and Galphaq-dependent activation of phosphatidylinositol 3-kinase. Biochemistry 2006; 45:9374 - 9385
   PubMed Web of Science ®Google Scholar
• Fukumoto S, Hsieh CM, Maemura K, Layne MD, Yet SF, Lee KH, et al. Akt participation in the Wnt signaling pathway through Dishevelled. J Biol Chem 2001; 276:17479 - 17483
   PubMed Web of Science ®Google Scholar
• Bryja V, Gradl D, Schambony A, Arenas E, Schulte G. Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc Natl Acad Sci USA 2007; 104:6690 - 6695
   PubMed Web of Science ®Google Scholar
• Bryja V, Schulte G, Arenas E. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell Signal 2007; 19:610 - 616
   PubMed Web of Science ®Google Scholar
• Bryja V, Schulte G, Rawal N, Grahn A, Arenas E. Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J Cell Sci 2007; 120:586 - 595
   PubMed Web of Science ®Google Scholar
• Cross JC, Baczyk D, Dobric N, Hemberger M, Hughes M, Simmons DG, et al. Genes, development and evolution of the placenta. Placenta 2003; 24:123 - 130
   PubMed Web of Science ®Google Scholar
• Aplin JD, Straszewski-Chavez SL, Kalionis B, Dunk C, Morrish D, Forbes K, et al. Trophoblast differentiation: progenitor cells, fusion and migration—a workshop report. Placenta 2006; 27:141 - 143
   Web of Science ®Google Scholar
• Even-Ram S, Uziely B, Cohen P, Grisaru-Granovsky S, Maoz M, Ginzburg Y, et al. Thrombin receptor overexpression in malignant and physiological invasion processes. Nat Med 1998; 4:909 - 914
   PubMed Web of Science ®Google Scholar
• Even-Ram SC, Grisaru-Granovsky S, Pruss D, Maoz M, Salah Z, Yong-Jun Y, et al. The pattern of expression of protease-activated receptors (PARs) during early trophoblast development. J Pathol 2003; 200:47 - 52
   PubMed Web of Science ®Google Scholar
• Grisaru-Granovsky S, Maoz M, Barzilay O, Yin YJ, Prus D, Bar-Shavit R. Protease activated receptor-1, PAR1, promotes placenta trophoblast invasion and beta-catenin stabilization. J Cell Physiol 2009; 218:512 - 521
   PubMed Web of Science ®Google Scholar
• Sonderegger S, Haslinger P, Sabri A, Leisser C, Otten JV, Fiala C, et al. Wingless (Wnt)-3A induces trophoblast migration and matrix metalloproteinase-2 secretion through canonical Wnt signaling and protein kinase B/AKT activation. Endocrinology 151:211 - 220
   PubMed Web of Science ®Google Scholar
• Dhanasekaran N, Dermott JM. Signaling by the G12 class of G proteins. Cell Signal 1996; 8:235 - 245
   PubMed Web of Science ®Google Scholar
• Simon MI, Strathmann MP, Gautam N. Diversity of G proteins in signal transduction. Science 1991; 252:802 - 808
   PubMed Web of Science ®Google Scholar
• Chan AM, Fleming TP, McGovern ES, Chedid M, Miki T, Aaronson SA. Expression cDNA cloning of a transforming gene encoding the wild-type Galpha12 gene product. Mol Cell Biol 1993; 13:762 - 768
   PubMed Web of Science ®Google Scholar
• Radhika V, Dhanasekaran N. Transforming G proteins. Oncogene 2001; 20:1607 - 1614
   PubMed Web of Science ®Google Scholar
• Jiang H, Wu D, Simon MI. The transforming activity of activated Galpha12. FEBS Lett 1993; 330:319 - 322
   PubMed Web of Science ®Google Scholar
• Vara Prasad MV, Shore SK, Dhanasekaran N. Activated mutant of Galpha13 induces Egr-1, c-fos and transformation in NIH 3T3 cells. Oncogene 1994; 9:2425 - 2429
   PubMed Web of Science ®Google Scholar
• Voyno-Yasenetskaya TA, Pace AM, Bourne HR. Mutant alpha subunits of G12 and G13 proteins induce neoplastic transformation of Rat-1 fibroblasts. Oncogene 1994; 9:2559 - 2565
   PubMed Web of Science ®Google Scholar
• Xu N, Voyno-Yasenetskaya T, Gutkind JS. Potent transforming activity of the G13alpha subunit defines a novel family of oncogenes. Biochem Biophys Res Commun 1994; 201:603 - 609
   PubMed Web of Science ®Google Scholar
• Kumar RN, Shore SK, Dhanasekaran N. Neoplastic transformation by the gep oncogene, Galpha12, involves signaling by STAT3. Oncogene 2006; 25:899 - 906
   PubMed Web of Science ®Google Scholar
• Parks GD, Lamb RA. Topology of eukaryotic type II membrane proteins: importance of N-terminal positively charged residues flanking the hydrophobic domain. Cell 1991; 64:777 - 787
   PubMed Web of Science ®Google Scholar
• Offermanns S, Mancino V, Revel JP, Simon MI. Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency. Science 1997; 275:533 - 536
   PubMed Web of Science ®Google Scholar
• Ruppel KM, Willison D, Kataoka H, Wang A, Zheng YW, Cornelissen I, et al. Essential role for Galpha13 in endothelial cells during embryonic development. Proc Natl Acad Sci USA 2005; 102:8281 - 8286
   PubMed Web of Science ®Google Scholar
• Gong H, Shen B, Flevaris P, Chow C, Lam SC, Voyno-Yasenetskaya TA, et al. G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin “outside-in” signaling. Science 2010; 327:340 - 343
   PubMed Web of Science ®Google Scholar
• Torres MA, Nelson WJ. Colocalization and redistribution of dishevelled and actin during Wnt-induced mesenchymal morphogenesis. J Cell Biol 2000; 149:1433 - 1442
   PubMed Web of Science ®Google Scholar