Ubiquitin receptor binding and signaling in primary human leukocytes

References

• Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem 1998; 67:425 - 479
   PubMed Web of Science ®Google Scholar
• Majetschak M. Extracellular ubiquitin: immune modulator and endogenous opponent of damage-associated molecular pattern molecules. J Leukoc Biol 2010; In press
   PubMed Web of Science ®Google Scholar
• Saini V, Marchese A, Majetschak M. CXC chemokine receptor 4 is a cell surface receptor for extracellular ubiquitin. J Biol Chem 2010; 285:15566 - 15576
   PubMed Web of Science ®Google Scholar
• Gupta SK, Pillarisetti K. Cutting edge: CXCR4-Lo: molecular cloning and functional expression of a novel human CXCR4 splice variant. J Immunol 1999; 163:2368 - 2372
   PubMed Web of Science ®Google Scholar
• Duchesneau P, Gallagher E, Walcheck B, Waddell TK. Upregulation of leukocyte CXCR4 expression by sulfatide: an L-selectin-dependent pathway on CD4+ T cells. Eur J Immunol 2007; 37:2949 - 2960
   PubMed Web of Science ®Google Scholar
• Busillo JM, Benovic JL. Regulation of CXCR4 signaling. Biochim Biophys Acta 2007; 1768:952 - 963
   PubMed Web of Science ®Google Scholar
• Murphy PM, Baggiolini M, Charo IF, Hebert CA, Horuk R, Matsushima K, et al. International union of pharmacology. Nomenclature for chemokine receptors. Pharmacol Rev 2000; 52:145 - 176
   PubMed Web of Science ®Google Scholar
• Bernhagen J, Krohn R, Lue H, Gregory JL, Zernecke A, Koenen RR, et al. MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nat Med 2007; 13:587 - 596
   PubMed Web of Science ®Google Scholar
• Balabanian K, Lagane B, Infantino S, Chow KY, Harriague J, Moepps B, et al. The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem 2005; 280:35760 - 35766
   PubMed Web of Science ®Google Scholar
• Bosier B, Muccioli GG, Hermans E, Lambert DM. Functionally selective cannabinoid receptor signalling: therapeutic implications and opportunities. Biochem Pharmacol 2010; 80:1 - 12
   PubMed Web of Science ®Google Scholar
• Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ. beta-arrestin-biased agonism at the beta2-adrenergic receptor. J Biol Chem 2008; 283:5669 - 5676
   PubMed Web of Science ®Google Scholar
• Rajagopal S, Rajagopal K, Lefkowitz RJ. Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nat Rev Drug Discov 2010; 9:373 - 386
   PubMed Web of Science ®Google Scholar
• Sachpatzidis A, Benton BK, Manfredi JP, Wang H, Hamilton A, Dohlman HG, et al. Identification of allosteric peptide agonists of CXCR4. J Biol Chem 2003; 278:896 - 907
   PubMed Web of Science ®Google Scholar
• Majetschak M, Krehmeier U, Bardenheuer M, Denz C, Quintel M, Voggenreiter G, et al. Extracellular ubiquitin inhibits the TNFalpha response to endotoxin in peripheral blood mononuclear cells and regulates endotoxin hyporesponsiveness in critical illness. Blood 2003; 101:1882 - 1890
   PubMed Web of Science ®Google Scholar
• Garcia-Covarrubias L, Manning EW 3rd, Sorell LT, Pham SM, Majetschak M. Ubiquitin enhances the Th2 cytokine response and attenuates ischemiareperfusion injury in the lung. Crit Care Med 2008; 36:979 - 982
   PubMed Web of Science ®Google Scholar
• Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N. CXCL12 (SDF-1alpha) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells. J Exp Med 2008; 205:2643 - 2655
   PubMed Web of Science ®Google Scholar
• Zheng H, Dai T, Zhou B, Zhu J, Huang H, Wang M, et al. SDF-1alpha/CXCR4 decreases endothelial progenitor cells apoptosis under serum deprivation by PI3K/Akt/eNOS pathway. Atherosclerosis 2008; 201:36 - 42
   PubMed Web of Science ®Google Scholar
• Shyu WC, Lin SZ, Yen PS, Su CY, Chen DC, Wang HJ, et al. Stromal cell-derived factor-1alpha promotes neuroprotection, angiogenesis and mobilization/homing of bone marrow-derived cells in stroke rats. J Pharmacol Exp Ther 2008; 324:834 - 849
   PubMed Web of Science ®Google Scholar
• Hu X, Dai S, Wu WJ, Tan W, Zhu X, Mu J, et al. Stromal cell derived factor-1alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1alpha CXCR4 axis. Circulation 2007; 116:654 - 663
   PubMed Web of Science ®Google Scholar
• Majetschak M, Cohn SM, Nelson JA, Burton EH, Obertacke U, Proctor KG. Effects of exogenous ubiquitin in lethal endotoxemia. Surgery 2004; 135:536 - 543
   PubMed Web of Science ®Google Scholar
• Majetschak M, Cohn SM, Obertacke U, Proctor KG. Therapeutic potential of exogenous ubiquitin during resuscitation from severe trauma. J Trauma 2004; 56:991 - 999
   PubMed Web of Science ®Google Scholar
• Earle SA, Proctor KG, Patel MB, Majetschak M. Ubiquitin reduces fluid shifts after traumatic brain injury. Surgery 2005; 138:431 - 438
   PubMed Web of Science ®Google Scholar
• Griebenow M, Casalis P, Woiciechowsky C, Majetschak M, Thomale UW. Ubiquitin reduces contusion volume after controlled cortical impact injury in rats. J Neurotrauma 2007; 24:1529 - 1535
   PubMed Web of Science ®Google Scholar
• Earle SA, El-Haddad A, Patel MB, Ruiz P, Pham SM, Majetschak M. Prolongation of skin graft survival by exogenous ubiquitin. Transplantation 2006; 82:1544 - 1546
   PubMed Web of Science ®Google Scholar
• Ahn HC, Yoo KY, Hwang IK, Cho JH, Lee CH, Choi JH, et al. Ischemia-related changes in naive and mutant forms of ubiquitin and neuroprotective effects of ubiquitin in the hippocampus following experimental transient ischemic damage. Exp Neurol 2009; 220:120 - 132
   PubMed Web of Science ®Google Scholar
• Singh M, Roginskaya M, Dalal S, Menon B, Kaverina E, Boluyt MO, et al. Extracellular ubiquitin inhibits beta-AR-stimulated apoptosis in cardiac myocytes: role of GSK-3beta and mitochondrial pathways. Cardiovasc Res 2010; 86:20 - 28
   PubMed Web of Science ®Google Scholar
• Ozkaynak E, Finley D, Varshavsky A. The yeast ubiquitin gene: head-to-tail repeats encoding a polyubiquitin precursor protein. Nature 1984; 312:663 - 666
   PubMed Web of Science ®Google Scholar